Best Sinus Medicine for Fever of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 7, 2025

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Sinus medicine for fever is a popular remedy for those who suffer from sinusitis and colds. These medicines are designed to relieve the symptoms of fever, headaches, and nasal congestion caused by sinus infection. Some common ingredients in these medicines include acetaminophen, ibuprofen, and pseudoephedrine. These medications come in various forms, including tablets, capsules, and liquids. It is important to follow the dosage instructions carefully to avoid any potential side effects. Sinus medicine for fever can provide fast relief from uncomfortable symptoms and help to improve overall health and well-being.

At a Glance: Our Top Picks

Advil Sinus Congestion and Pain Tablets Cover #TOP 1
Advil Sinus Congestion and Pain Tablets
ftb score rating icon 9.8
Advil Sinus Congestion and Pain, Sinus Relief Medicine - 20 Coated Tablets Cover #TOP 2
Advil Sinus Congestion and Pain, Sinus Relief Medicine - 20 Coated Tablets
ftb score rating icon 9.7
Tylenol Cold + Flu Severe Caplets Cover #TOP 3
Tylenol Cold + Flu Severe Caplets
ftb score rating icon 9.5

Top 10 Sinus Medicine for Fever

Advil Sinus Congestion and Pain Tablets

305730199117
Advil Sinus Congestion and Pain Tablets Cover
Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 10 Coated Tablets

Advil Sinus Relief Medicine is a pain reliever and fever reducer with ibuprofen and phenylephrine HCl. It comes in a package of 10 coated tablets, making it easy to carry around and use whenever you need it. The ibuprofen helps to temporarily relieve fever, minor body aches and headache. The phenylephrine HCl tablets provide relief from sinus pressure, nasal congestion, and nasal swelling. This daytime or nighttime sinus medicine is suitable for adults and children aged 12 years and older. Take one of these sinus decongestant tablets every 4 hours as needed for symptoms.

What We Like
Relieves sinus pressure
Temporarily reduces fever
Easy to carry and use
#TOP 2

Advil Sinus Congestion and Pain, Sinus Relief Medicine - 20 Coated Tablets

305730199216
Multi
Advil Sinus Congestion and Pain, Sinus Relief Medicine - 20 Coated Tablets Cover
Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 20 Coated Tablets

Advil Sinus Congestion and Pain is a pain reliever and fever reducer medicine that also provides sinus pressure relief, nasal congestion relief, and nasal swelling relief. Each package comes with 20 coated tablets that are portable and easy to carry around. This sinus medicine is suitable for adults and children who are 12 years and older. It contains ibuprofen 200mg and Phenylephrine HCl 10 mg, and you can take one of these tablets every 4 hours as needed for symptoms.

What We Like
Provides relief for sinus pressure, nasal congestion, and swelling.
Coated tablets are portable and easy to carry around.
Contains ibuprofen 200mg and Phenylephrine HCl 10 mg.
#TOP 3

Tylenol Cold + Flu Severe Caplets

30045055024
24 Count
Tylenol Cold + Flu Severe Caplets Cover
Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Tylenol Cold + Flu Severe Day & Night Caplets are formulated to provide multi-symptom relief for cold and flu symptoms. The 24-count combo pack includes 16 Daytime and 8 Nighttime caplets that help reduce fever, relieve headache, body aches, cough, sore throat, nasal congestion, chest congestion, runny nose, sneezing, sinus congestion, and pressure. Each caplet contains acetaminophen, a pain reliever and fever reducer, and other active ingredients such as a nasal decongestant, cough suppressant, antihistamine, and expectorant. This product is from the #1 doctor recommended pain relief brand.

What We Like
Provides multi-symptom relief for cold and flu symptoms
Includes Daytime and Nighttime caplets for any time of the day
Contains active ingredients such as acetaminophen, nasal decongestant, cough suppressant, antihistamine, and expectorant
#TOP 4

Advil Sinus Congestion and Pain Relief Medicine, 50 Count

305730199018
As Shown
Advil Sinus Congestion and Pain Relief Medicine, 50 Count Cover
Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 50 Coated Tablets

Advil Sinus Congestion and Pain Relief Medicine is a combination of ibuprofen and phenylephrine HCl that provides temporary relief from fever, minor body aches, headache, sinus pressure, nasal congestion, and nasal swelling. The coated tablets are portable and easy to carry, making it a perfect on-the-go solution. It is suitable for adults and children aged 12 years and older. This product comes with single dose packets and is HSA and FSA eligible.

What We Like
Provides temporary relief from multiple symptoms
Portable and easy to carry
Suitable for adults and children aged 12 years and older
#TOP 5

Mucinex Nightshift Sinus Caplets

Multi
Mucinex Nightshift Sinus Caplets Cover
Mucinex Nightshift Sinus, Maximum Strength Powerful MultiSymptom Night Relief, 20 Fast Release Caplets Pain Reliever/Fever Reducer, Cough Suppressant, Nasal Decongestant & Antihistamine

Mucinex Nightshift Sinus offers maximum strength relief for your nighttime symptoms. These fast-release caplets effectively tackle headaches, sore throats, sneezing, and nasal congestion, helping you to sleep better. As the #1 trusted cold and cough brand among doctors, you can feel confident using this product. Each caplet contains key ingredients like acetaminophen for pain relief and dextromethorphan to suppress coughs. Plus, it is FSA and HSA eligible, allowing you to save on out-of-pocket expenses. With Mucinex Nightshift Sinus, you can wake up feeling refreshed and ready for the day.

What We Like
Effective nighttime symptom relief
Trusted by healthcare professionals
FSA and HSA eligible
Fast-release formula
#TOP 6

Advil Allergy and Congestion Relief Tablets

305730196017
Advil Allergy and Congestion Relief Tablets Cover
Advil Allergy and Congestion Relief Tablets, Pain Reliever, Fever Reducer and Allergy Relief with Ibuprofen, Phenylephrine HCl and Chlorpheniramine Maleate 4 mg - 50 Coated Tablets

Advil Allergy and Congestion Relief Tablets are a combination of ibuprofen, phenylephrine HCl and chlorpheniramine maleate 4 mg that help to temporarily relieve fever, body aches, headache, sinus pressure, nasal congestion, runny nose and nasal swelling. These coated tablets are easily portable, making it convenient for you to carry wherever you go. Suitable for adults and children over 12 years old.

What We Like
Provides relief for multiple symptoms
Coated tablets for easy swallowing
Portable packaging for on-the-go relief

Tylenol Sinus + Headache Daytime Caplets

JJ-2320
Original
Tylenol Sinus + Headache Daytime Caplets Cover
Tylenol Sinus + Headache Daytime Non-Drowsy Relief Caplets, Acetaminophen 325mg, Nasal Decongestant for Sinus Pressure, Headache & Nasal Congestion Relief, 24 ct

Tylenol Sinus + Headache Daytime Caplets are formulated to temporarily relieve symptoms of nasal congestion, sinus headache, and pressure. Each caplet contains 325 mg of acetaminophen and 5 mg of phenylephrine HCl, which helps clear nasal passages. The non-drowsy formula promotes sinus drainage and decongests sinus openings and passages, providing effective daytime symptom relief. Suitable for adults and children ages 12 years and older, this sinus medicine is doctor-recommended.

What We Like
Temporarily relieves symptoms of nasal congestion, sinus headache, and pressure
Non-drowsy formula promotes sinus drainage and decongests sinus openings and passages
Contains 325 mg of acetaminophen and 5 mg of phenylephrine HCl, which helps clear nasal passages
#TOP 8

Sudafed PE Sinus Pressure + Pain Relief Non-Drowsy Decongestant, 24 Count

300450547248
Sudafed PE Sinus Pressure + Pain Relief Non-Drowsy Decongestant, 24 Count Cover
Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 24 ct

Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant contains 24 caplets that provide powerful relief of sinus pain, sinus pressure, nasal congestion, headaches, and fever. Each caplet contains 5mg phenylephrine HCl and 325mg acetaminophen, and can also relieve nasal congestion associated with hay fever, respiratory allergies, and the common cold. The non-drowsy decongestant promotes sinus drainage, reduces fever, and helps relieve headaches and minor aches and pain. This maximum strength formula is recommended by pharmacists for adults and children over 12 years old.

What We Like
Provides powerful relief of sinus pain, pressure, congestion, headaches, and fever
Contains phenylephrine HCl and acetaminophen
Relieves nasal congestion associated with hay fever, allergies, and the common cold
#TOP 9

Sudafed PE Head Congestion + Mucus Tablets

Sudafed PE Head Congestion + Mucus Tablets Cover
Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct

Sudafed Head Congestion Tablets is a non-drowsy sinus relief medicine that provides relief from sinus pain and pressure, nasal and chest congestion, and excess mucus. With its powerful formula containing phenylephrine HCl, acetaminophen, and guaifenesin, it effectively reduces congestion, relieves pain and fever, and helps to clear bronchial passageways. Whether you're suffering from hay fever, upper respiratory allergies, or the common cold, these tablets can provide temporary relief from symptoms. Say goodbye to sinus pressure, headaches, and minor aches and pains with Sudafed Head Congestion Tablets, the #1 pharmacist recommended brand among oral OTC decongestants.

What We Like
Non-drowsy relief
Clears bronchial passageways
Relieves sinus pressure and headaches
#TOP 10

AXIV Sinus Severe + Mucus Relief

AXIV
Turquoise Blue
AXIV Sinus Severe + Mucus Relief Cover
AXIV Sinus Severe + Mucus Relief, Non-Drowsy, Loosens Mucus, Maximum Strength Relief of Pain, Pressure, Congestion, & Headache Relief, 24 Softgels.

AXIV Sinus Relief offers fast and effective relief from various sinus and respiratory symptoms. This powerful formula helps you clear nasal congestion, alleviate sinus pressure, and ease headaches, allowing you to breathe easier. It promotes drainage and thins mucus, making it particularly useful for those suffering from colds or allergies. With easy-to-swallow softgels, you can conveniently take two every four hours as needed, ensuring you stay comfortable throughout the day without feeling drowsy. Experience the relief you deserve with this maximum strength solution.

What We Like
Fast-acting relief
Multi-symptom support
Convenient softgel dosage
Non-drowsy formula
Buying Guide Image
Editor's Notes

During our sinus medicine for fever research, we found 24 sinus medicine for fever products and shortlisted 10 quality products. We collected and analyzed 258,990 customer reviews through our big data system to write the sinus medicine for fever list. We found that most customers choose sinus medicine for fever with an average price of $11.07.

The sinus medicine for fever are available for purchase. We have researched hundreds of brands and picked the top brands of sinus medicine for fever, including Advil, Tylenol, Mucinex, TENA, AXIV. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.