Best Liquid Sinus Medicine of 2025

Children's Sudafed PE Nasal Decongestant provides a non-drowsy formula that helps relieve nasal congestion and sinus pressure in children aged 4-11 due to common cold and hay fever. The alcohol-free and sugar-free formula includes phenylephrine HCl as a nasal decongestant, and the kid-friendly berry flavor makes it suitable for children. This medicine is available in a 4-fluid ounce bottle.

Mucinex Sinus-Max Max Strength Pressure, Pain & Cough Liquid Gels provide maximum strength relief for cough, stuffy nose, chest & nasal congestion, headache and minor aches and pains. It is the #1 trusted cold & cough brand that doctors recommend. This medicine contains Acetaminophen that relieves minor aches, pains and headache; Dextromethorphan HBr that helps relieve cough; Guaifenesin that thins and loosens mucus and relieves chest congestion; Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure. It is suitable for people aged 12+ years.

Zicam Congestion Relief Spray provides quick relief from nasal congestion and sinus pressure for up to 12 hours, making it ideal for those suffering from cold or allergy symptoms. Its unique no-drip formula ensures that the spray stays in your nose, preventing any unpleasant aftertaste that often comes with other nasal sprays. You can also explore their AllClear nasal swabs for an easy and mess-free way to tackle discomfort. Zicam offers a range of products designed not only for congestion relief but also for homeopathic cold shortening and allergy relief, giving you multiple options for your health needs.

Mucinex is a trusted brand of sinus medicine that doctors and pharmacists recommend. It offers maximum strength relief for severe congestion and pain. This pack includes two 6 Fl Oz bottles of Mucinex Maximum Strength Sinus-Max Severe Congestion & Pain and Nightshift Sinus Liquid.

Zicam Sinus Relief Spray is a fast-acting nasal decongestant spray that provides up to 12 hours of relief from nasal congestion and sinus pressure caused by cold and allergy symptoms. With the added benefits of cooling menthol and eucalyptus, this no-drip liquid nasal spray offers a convenient and mess-free solution. Unlike many saline nasal sprays, Zicam's formulation ensures it won't drip down your throat, providing relief without any unpleasant aftertaste. For those seeking safe and effective relief on-the-go, Zicam also offers AllClear nasal swabs that are quick and easy to use. In addition to its congestion relief products, Zicam provides a range of homeopathic cold shortening and allergy relief options. Breathe more easily with Zicam Sinus Relief Spray, and experience the satisfaction of fast-acting relief.

Dr. Christopher Sinus Plus is a 2 oz liquid designed to provide relief for sinus congestion and discomfort. Made by Christopher's Original Formulas, this product is formulated with natural ingredients to help soothe and clear the sinuses. With a package dimension of 7.1"L x 2.5"W x 2.2"H, it is compact and easy to carry. The country of origin is the United States, ensuring high quality. The Sinus Plus liquid is suitable for those seeking a natural remedy for sinus issues. It can help to alleviate congestion, reduce inflammation, and promote sinus health. With Dr. Christopher Sinus Plus, you can find relief and breathe easier.

Kids Relief Sinus Oral Liquid is a safe and natural homeopathic medicine that helps relieve symptoms associated with sinus congestion in children ages 0-12. The liquid comes in a great tasting raspberry flavor and is easy to measure with the included dropper. The medicine is manufactured using all-natural active ingredients and is free of gluten, dye, sugar, and drug interactions. The child-proof cap adds an extra layer of safety. Mothers have trusted Kids Relief products since 1993.

Zicam Intense Sinus Relief is a fast-acting nasal decongestant spray that provides up to 12 hours of relief from nasal congestion and sinus pressure caused by cold and allergy symptoms. It contains cooling menthol and eucalyptus and is a no-drip formula that won't leave an unpleasant aftertaste like many saline nasal sprays. Zicam also offers a range of products for homeopathic cold shortening and allergy relief, including convenient and mess-free nasal swabs. Satisfaction is guaranteed.