Best Omega-3 CoQ10 Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 10, 2025

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Omega-3 CoQ10 supplements are a popular health supplement that combines two powerful ingredients for optimal health benefits. Omega-3 fatty acids are essential for maintaining a healthy heart and brain function, while CoQ10 is necessary for energy production and overall cellular health. These supplements are often recommended for individuals who suffer from high blood pressure, high cholesterol, or cardiovascular disease. They are also beneficial for athletes and active individuals looking to improve their athletic performance and recovery. Omega-3 CoQ10 supplements are available in various forms, including softgels, capsules, and liquids, and can be found at most health food stores and online retailers.

At a Glance: Our Top Picks

Nordic Naturals Ultimate Omega + CoQ10, Lemon Cover #TOP 1
Nordic Naturals Ultimate Omega + CoQ10, Lemon
ftb score rating icon 9.9
THORNE Omega-3 with CoQ10 Cover #TOP 2
THORNE Omega-3 with CoQ10
ftb score rating icon 9.8
Clean Nutra CardioGuard Supplement Cover #TOP 3
Clean Nutra CardioGuard Supplement
ftb score rating icon 9.6

Top 10 Omega-3 CoQ10 Supplements

#TOP 1

Nordic Naturals Ultimate Omega + CoQ10, Lemon

RUS-01892
Blue
Nordic Naturals Ultimate Omega + CoQ10, Lemon Cover
Nordic Naturals Ultimate Omega + CoQ10, Lemon - 120 Soft Gels - 1280 mg Omega-3 + 100 mg CoQ10 - Heart Health, Cellular Energy, Antioxidant Support - Non-GMO - 60 Servings

Try Nordic Naturals Ultimate Omega + CoQ10 for cardiovascular health, normal cellular energy levels, and antioxidant support. It combines high-potency, concentrated fish oil and Coenzyme Q10 to combat aging and maintain natural CoQ10 levels. With the triglyceride molecular form, it ensures better absorption, better taste, and no fishy burps. You can trust the purity of this non-GMO, gluten and dairy-free product which has been third-party tested. This product is recommended for people with cardiovascular concerns, performance athletes, and anyone over the age of 40.

What We Like
Combines high-potency, concentrated fish oil and Coenzyme Q10 for cardiovascular health, normal cellular energy levels, and antioxidant support.
Helps maintain natural CoQ10 levels, which have been shown to decrease with age, combating aging.
Triglyceride molecular form ensures better absorption, better taste, and no fishy burps.
Non-GMO, gluten and dairy-free product which has been third-party tested, ensuring purity.
Recommended for people with cardiovascular concerns, performance athletes, and anyone over the age of 40.
#TOP 2

THORNE Omega-3 with CoQ10

SP616
THORNE Omega-3 with CoQ10 Cover
THORNE Omega-3 with CoQ10 - Omega-3 Fatty Acids Supplement with CoQ10 - EPA and DHA - 90 Gelcaps

THORNE Omega-3 CoQ10 Gelcaps offer a dual action formula combining heart-healthy essential fatty acids with Coenzyme Q10. These gelcaps support cardiovascular health by promoting healthy blood vessel function and maintaining cholesterol levels. They also help in maintaining healthy brain function and cellular energy production. Made from pure fish oil sourced sustainably, these gelcaps undergo molecular distillation to remove contaminants. Enjoy the benefits of two great products in one convenient gelcap with THORNE Omega-3 CoQ10 Gelcaps.

What We Like
Heart-healthy essential fatty acids
Supports cardiovascular health
Helps maintain brain function
#TOP 3

Clean Nutra CardioGuard Supplement

COQ10
White
Clean Nutra CardioGuard Supplement Cover
Clean Nutraceuticals COQ10 Red Yeast Rice Omega 3 Magnesium Complex Niacin Zinc Vitamin K2 D3 - Heart Support Vitamins for Women & Men w/Vitamin B3, Coenzyme Q10-60 Ct

Clean Nutra CardioGuard is an all-in-one supplement that combines Coenzyme Q10, Red Yeast Rice, Omega 3, Magnesium Complex, Niacin, Zinc, Vitamin K2 and Vitamin D3. It offers more potent dosages than regular CoQ10 and red yeast rice supplements. The formula is made in the USA with trusted ingredients and doesn't contain any preservatives or fillers.

What We Like
Offers 8 full-dose products in one complex
Contains more potent dosages than regular CoQ10 and red yeast rice supplements
Made in the USA with trusted ingredients and doesn't contain any preservatives or fillers
#TOP 4

Qunol Plus Ubiquinol CoQ10 200mg with Omega 3 Fish Oil

11969SEG90B
Qunol Plus Ubiquinol CoQ10 200mg with Omega 3 Fish Oil Cover
Qunol Plus Ubiquinol + Omega 3, Ubiquinol CoQ10 200mg with 250mg Omega-3 Fish Oil, Extra Strength, Antioxidant for Heart Health, Natural Supplement for Energy Production, (Bovine Version), 90 Count

Qunol Plus Ubiquinol CoQ10 200mg with Omega 3 Fish Oil is a powerful heart health supplement that contains Ubiquinol, the active form of CoQ10, and Omega-3, an essential fatty acid. With a single daily dose, users can enjoy the benefits of these two doctor-recommended heart nutrients. Ubiquinol helps fight excess free radicals, protect cells against damage, and plays an important role in the production of 95% of the energy used by organs. Omega-3 is essential for the body since it does not produce it and most people do not get the recommended daily levels of Omega-3 from their diets alone.

What We Like
Contains Ubiquinol, the active form of CoQ10
Includes Omega-3, an essential fatty acid
Helps fight excess free radicals and protects cells against damage
Plays an important role in the production of 95% of the energy used by organs
Gluten-free

ZEBORA CoQ10-200mg-Softgels

ZBFMQ10-J200MG120
ZEBORA CoQ10-200mg-Softgels Cover
CoQ10-200mg-Softgels with PQQ, BioPerine & Omega-3, 120 Servings Coenzyme Q10(Ubiquinone) Supplement for High-Absorption, Powerful-Antioxidant, Support Heart & Energy-Production

ZEBORA CoQ10-200mg-Softgels provides enhanced CoQ10 and PQQ for heart function and energy production, blended with Black Pepper Extract and Sunflower Lecithin for better absorption and bioavailability, and combined with Omega-3s for heart health, better sleep, and brain function. It is also beneficial for statin drug users, as it helps replenish lost CoQ10. The product is high quality, third-party tested, and manufactured in a cGMP-certified facility.

What We Like
Easy to swallow
Reasonably priced
Effective dosage
Small gelcap size
Includes omega-3 fish oil
#TOP 6

NOW CoQ10 60mg with Omega 3 Fish Oil Softgels

3166
Red/Brown
NOW CoQ10 60mg with Omega 3 Fish Oil Softgels Cover
NOW Foods Supplements, CoQ10 60 mg with Omega 3 Fish Oil, Cardiovascular Health*, 120 Softgels

The NOW CoQ10 60mg with Omega 3 Fish Oil Softgels combines two complementary ingredients that support cardiovascular health, heart function and cellular energy production. The softgels contain no titanium dioxide and are Halal, Kosher, Dairy Free, Egg Free and Made without Gluten. The product is GMP Quality Assured with NPA A-rated GMP certification, ensuring a high quality manufacturing process. The softgels are packaged in the USA by a family owned company since 1968, and may arrive warm during summer months, but they are shipped in accordance with manufacturers' recommendations.

What We Like
Combines two complementary ingredients that support cardiovascular health
Contains no titanium dioxide and is Halal, Kosher, Dairy Free, Egg Free and Made without Gluten
GMP Quality Assured with NPA A-rated GMP certification, ensuring high quality manufacturing process
Softgels are packaged in the USA by a family owned company since 1968
#TOP 7

Qunol Plus Ubiquinol CoQ10 100mg with Omega 3 Fish Oil, 90 Count

898440001226
90 Count
Qunol Plus Ubiquinol CoQ10 100mg with Omega 3 Fish Oil, 90 Count Cover
Qunol Plus Ubiquinol with Omega-3 Fish Oil - Antioxidant Supplement for Heart Health and Energy Production, Active Form of CoQ10, 90 Count

The Qunol Plus Ubiquinol CoQ10 supplement is a powerful antioxidant that helps support cellular energy production with its active form of CoQ10, Ubiquinol. It also contains an essential fatty acid, omega-3, which provides a range of health benefits. This supplement is doctor-recommended and contains 100 mg of ubiquinol and 250 mg of omega-3, giving you the benefits of both nutrients with a single daily dose. Ubiquinol helps neutralize free radicals, protect cells against damage, and is essential for cellular energy production. Omega-3 is considered essential because most people do not get recommended daily levels from their diets alone.

What We Like
Contains both ubiquinol and omega-3, benefiting heart and vascular health with a single daily dose
Ubiquinol is a powerful antioxidant that helps neutralize free radicals and protect cells against damage
Essential for cellular energy production
#TOP 8

NatureBell CoQ10 (Ubiquinone) 400mg with Omega 3 Fatty Acids, 240 Capsules

CQ200C
NatureBell CoQ10 (Ubiquinone) 400mg with Omega 3 Fatty Acids, 240 Capsules Cover
NatureBell CoQ10 400mg with Omega 3 Fatty Acids, 240 Capsules | Stable High Absorption Form – Antioxidant Support for Heart & Energy Health – Extra Strength Coenzyme Q10 Supplement

NatureBell CoQ10 400mg with Omega 3 is a high-potency supplement that combines the power of CoQ10 and Omega-3 fatty acids to support heart health, boost energy levels, and provide antioxidant protection. CoQ10 and Omega-3 work together to maintain a healthy heart and overall wellness, while also promoting optimal energy and vitality. CoQ10 serves as a powerful antioxidant that neutralizes harmful free radicals, and Omega-3 fatty acids offer complementary support for a healthy immune system. With 240 easy-to-swallow capsules, this premium quality supplement ensures a lasting supply for your health needs.

What We Like
Increased energy levels
Improved cognitive function
Great value for cost
Recommended by healthcare professionals
Good for supplement cycling
#TOP 9

CoQ10 100mg with Omega 3 by DEAL SUPPLEMENT

BA-DS-COQ240
CoQ10 100mg with Omega 3 by DEAL SUPPLEMENT Cover
CoQ10 100mg, 240 Capsules – with Omega 3 Fatty Acid 100mg – Bioavailable Coenzyme Q10 Supplements – Heart, Energy, & Brain Health Antioxidant Support – Non-GMO

CoQ10 Omega 3 by DEAL offers a unique combination of 100mg Ubiquinone CoQ10 and 100mg Omega 3 Fatty Acids, providing essential support for your heart, brain, and energy levels. This supplement helps combat age-related decline by replenishing natural CoQ10 levels, promoting healthy aging. With a convenient 240-capsule supply, you can easily incorporate it into your daily routine. The non-GMO ingredients are third-party lab tested, ensuring quality and safety. Enjoy the benefits of improved vitality and overall well-being with this powerful antioxidant support.

What We Like
Improves memory
Increases energy levels
Affordable price
Easy to swallow
Contains Omega-3

Garden of Life Vegetarian Omega 3 6 9 Supplement

Garden of Life Vegetarian Omega 3 6 9 Supplement Cover
Garden of Life CoQ10 200mg, Vegetarian Omega 3 6 9 Supplement Raw Co Q 10 Chia Seed Oil, Whole Food Nutrition with Antioxidant Support, Coenzyme q10 Supplement for Heart Health, 60 Capsules

Garden of Life Vegetarian Omega 3 6 9 Supplement is a powerful antioxidant supplement that supports cardiovascular function and heart health. It is made from raw, vegan, gluten-free, dairy-free, and live probiotic ingredients, and provides support for cellular growth, energy production, physical performance, healthy aging, and digestive health. Customers have reported increased energy, improved cholesterol levels, and strengthened nails.

What We Like
Improves energy levels
Reduces LDL cholesterol
Improves heart and nail health
Suitable for vegetarians and fish-allergic individuals
Tested and shown to be clean by consumer lab reports
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is it OK to take omega-3 and CoQ10 together?

Yes, taking omega-3 and CoQ10 together can be beneficial. CoQ10 helps generate energy in your cells, and combining it with omega-3 from pure fish oil can enhance absorption and utilization of CoQ10.

2. Do I need CoQ10 and omega-3?

Both CoQ10 and omega-3 have their own benefits and can complement each other. It's not an either/or choice. However, it's always a good idea to consult with your doctor before taking any supplements to determine if they are suitable for you.

3. Is there any downside to taking CoQ10?

While most people tolerate CoQ10 well, some mild side effects may occur, such as stomach upset, loss of appetite, nausea, vomiting, diarrhea, and allergic skin rashes. It may also lower blood pressure, so it's important to monitor your blood pressure if you have low blood pressure.

4. What should you not mix omega-3 with?

Possible interactions to be aware of include anticoagulant and antiplatelet drugs, as well as certain herbs and supplements that reduce blood clotting. Taking fish oil supplements along with these medications or supplements may increase the risk of bleeding.

5. Which is better for the heart CoQ10 or omega-3?

There isn't much research comparing the specific cardiovascular benefits of CoQ10 and omega-3. Both supplements have shown promising results in various factors related to heart health, such as blood pressure, heart rate, cholesterol levels, and disease risk.

6. How do you know if you need CoQ10?

CoQ10 deficiency may present with neurological abnormalities such as seizures, intellectual disability, poor muscle tone, involuntary muscle contractions, progressive muscle stiffness, abnormal eye movements, and vision loss. If you suspect a deficiency, consult with a healthcare professional for proper evaluation and guidance.

7. When should I take CoQ10, morning or night?

There is no standard guideline for the best time to take CoQ10. However, it is generally recommended to take it in the morning with a meal due to its potential energizing effects. As with any supplement, individual responses may vary, so a later-in-the-day dose might work for some people.

8. Why don't doctors recommend CoQ10?

CoQ10 may interact with blood-thinning drugs, such as warfarin, potentially reducing their effectiveness and increasing the risk of blood clots. Therefore, doctors may exercise caution and closely monitor patients who are on blood-thinning medications.

9. What happens when you take CoQ10 everyday?

Taking CoQ10 daily has been linked to various health benefits, including improved aging, exercise performance, heart health, diabetes, fertility, and migraines. The recommended daily dosage typically ranges from 90-200 mg, but higher dosages of 300-600 mg may be necessary for certain conditions. It's important to consult with a healthcare professional for appropriate dosing recommendations.

Editor's Notes

During our omega-3 coq10 supplement research, we found 24 omega-3 coq10 supplement products and shortlisted 10 quality products. We collected and analyzed 80,973 customer reviews through our big data system to write the omega-3 coq10 supplements list. We found that most customers choose omega-3 coq10 supplements with an average price of $20.94.

The omega-3 coq10 supplements are available for purchase. We have researched hundreds of brands and picked the top brands of omega-3 coq10 supplements, including Nordic Naturals, THORNE, Clean Nutraceuticals, Qunol, ZEBORA. The seller of top 1 product has received honest feedback from 5,586 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.