Best B3 Vitamin B12 Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 20, 2026

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B3 Vitamin B12 Supplements are a great addition to any healthy lifestyle. These supplements provide the body with a much-needed dose of vitamin B12, which is essential for maintaining healthy nerve cells and red blood cells. B12 is also important for DNA synthesis and energy production. These supplements are easy to take and can be added to any daily routine. They are especially beneficial for those who follow a vegan or vegetarian diet as B12 is primarily found in animal-based foods. Overall, B3 Vitamin B12 Supplements are a convenient and effective way to ensure the body receives the necessary nutrients for optimal health.

At a Glance: Our Top Picks

Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply Cover #TOP 1
Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply
ftb score rating icon 9.9
Nature’s Bounty Vitamin B12 2500 mcg Tablets Cover #TOP 2
Nature’s Bounty Vitamin B12 2500 mcg Tablets
ftb score rating icon 9.8
Nature's Bounty Vitamin B12, 1000mcg, 200 Ct Cover #TOP 3
Nature's Bounty Vitamin B12, 1000mcg, 200 Ct
ftb score rating icon 9.6

Top 10 B3 Vitamin B12 Supplements

Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply

3217
Pink
Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply Cover
Nature Made Vitamin B12 1000 mcg, Easy to Take Vitamin B12 Sublingual Tablets for Energy Metabolism Support, 150 Sugar Free Fast Dissolve Tablets, 150 Day Supply

Nature Made Vitamin B12 Sublingual Lozenges provide energy metabolism support, improve brain cell function, and promote proper red blood cell formation. The 1000 mcg lozenges have a great-tasting flavor, are easy to take, and are sugar-free. This 150-day supply is perfect for vegetarians and vegans who may not consume enough B12 from their diet alone. Made in the USA with quality ingredients, these lozenges are USP Verified and the number one pharmacist recommended vitamin and supplement brand.

What We Like
Quick-dissolving sublingual tablets
Pleasant cherry flavor
Reasonable price
Reliable energy boost
Trusted quality brand

Nature’s Bounty Vitamin B12 2500 mcg Tablets

58911
Green
Nature’s Bounty Vitamin B12 2500 mcg Tablets Cover
Nature’s Bounty Vitamin B12 2500 mcg, Cellular Energy Support, for Energy Metabolism, Heart & Nervous System Health, 75 Quick Dissolve Tablets

Nature’s Bounty Vitamin B12 2500 mcg Tablets are designed to help support your body’s energy metabolism, heart and nervous system health. With 75 quick dissolve tablets, this supplement is an easy and convenient way to ensure that your body gets the Vitamin B12 that it needs. Nature's Bounty is committed to quality and safety and this supplement is gluten-free, sugar-free, and contains no artificial flavors or sweeteners, making it suitable for vegetarians.

What We Like
Quick-dissolving tablets
Pleasant cherry flavor
Boosts energy and immunity
Vegetarian-friendly formula
High-quality and affordable

Nature's Bounty Vitamin B12, 1000mcg, 200 Ct

Nature's Bounty Vitamin B12, 1000mcg, 200 Ct Cover
Nature's Bounty Vitamin B12 1000 mcg Supplements, Supports Energy Metabolism, 200 Ct

Nature's Bounty B12 Tablets are a product of nearly 50 years of dedication to quality, consistency, and scientific research to make vitamins and nutritional supplements of unrivaled excellence. These tablets support cellular energy health by aiding in the conversion of food into cellular energy. They also support cardiovascular health and help maintain healthy nerves. The tablets are easy to swallow as they are coated, making them more convenient for users.

What We Like
Energy boost
Easy to take
Good value
No unpleasant aftertaste
High-quality supplement

Thorne Vitamin B12 Capsules

B125
Thorne Vitamin B12 Capsules Cover
THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Healthy Sleep & Methylation* - Gluten, Dairy & Soy-Free - 60 Servings

Thorne B12 is a vitamin B12 supplement that comes in capsule form. It contains Methyl-B12, a form of vitamin B12 that is easily absorbed by the body. Thorne B12 supports heart health and nerve function, helps maintain normal circadian rhythms to support restful sleep, and supports the body's healthy methylation processes. The supplement is gluten-free, soy-free, and dairy-free. Thorne is a trusted brand, chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of U.S. Olympic Teams. With Thorne B12, you can improve your heart and nerve health, sleep better, and support your body's natural processes.

What We Like
Energy boost
Supports B12 levels
No stomach upset
Methylated form
Physician recommended
#TOP 5

Nature Made Vitamin B12 1000 mcg Softgels

2916
150 Count
Nature Made Vitamin B12 1000 mcg Softgels Cover
Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, B12 Vitamins 1000 mcg, 150 Softgels, 150 Day Supply

Nature Made B12 Softgels is a dietary supplement that helps support energy metabolism, brain cell function, and red blood cell formation. With 1000 mcg of Vitamin B12 per softgel, this supplement can help break down food into energy that your body can use all day long. It also supports the production of neurotransmitters needed for mood health. For vegetarians and vegans who may not consume enough B12 from diet alone, this supplement is especially important. Simply take one softgel daily with water and a meal. Nature Made B12 Softgels are gluten-free, have no synthetic dyes, and no artificial flavors. As a USP verified product and #1 Pharmacist Recommended Vitamin and Supplement Brand, you can trust the quality and effectiveness of Nature Made B12 Softgels.

What We Like
Noticeable energy boost
Easy to swallow
No aftertaste or smell
High-quality ingredients
Long-lasting supply

Nature Made Maximum Strength Vitamin B12 5000 mcg Softgels

2886
No Artificial Color
Nature Made Maximum Strength Vitamin B12 5000 mcg Softgels Cover
Nature Made Maximum Strength Vitamin B12 5000 mcg, Dietary Supplement for Energy Metabolism Support, 60 Softgels, 60 Day Supply

Nature Made Maximum Strength Vitamin B12 5000 mcg Softgels is a dietary supplement that supports energy metabolism and brain cell function. It contains high-quality ingredients, is gluten-free and has no artificial flavors or preservatives. This supplement is essential for vegetarians and vegans who may not consume enough vitamin B12 from their diet alone. It is recommended to take one softgel daily with water and a meal for a 60-day supply.

What We Like
Easy to swallow
No taste
Small size
High vitamin quality
Affordable price

Pure Encapsulations B-Complex Plus Supplement

Pure Encapsulations B-Complex Plus Supplement Cover
Pure Encapsulations B-Complex Plus - B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* - with Vitamin B12 & More - 120 Capsules

The Pure Encapsulations B-Complex Plus Supplement is designed to support your nervous system, cognitive function, and cellular energy. It contains methylated folate and vitamin B12 to promote healthy nerve and blood cells, memory, and energy levels. The B vitamins in the supplement help convert carbohydrates into energy and support protein metabolism. The product is made with premium ingredients and tested for purity, and it is free from harmful additives such as gluten, artificial colors, flavors, and sweeteners.

What We Like
Clean, high-quality formulation
Supports energy and reduces fatigue
Gentle on stomach
Supports neurological and nerve health
No unnecessary fillers or allergens

Horbaach B12 Sublingual Methylcobalamin 5000mcg

CL1171
Horbaach B12 Sublingual Methylcobalamin 5000mcg Cover
Horbäach B12 Vitamin 5000 mcg | 120 Fast Dissolve Tablets | Sublingual Methylcobalamin | Vegetarian, Non-GMO & Gluten Free Supplement

Horbaach B12 Sublingual is a vitamin B12 supplement that comes in delicious natural berry flavor. Each fast dissolve tablet features a potent formula of 5000mcg vitamin B12 as methylcobalamin. The vegetarian formula is expertly crafted, backed by a commitment to purity and potency. The product is naturally free of gluten, yeast, milk, lactose, artificial flavoring, and non-GMO. The sublingual form of B12 ensures easy absorption by placing it under your tongue. This supplement can be beneficial for those who have a deficiency in vitamin B12, which can help improve energy levels, brain function, and support a healthy nervous system. The fast dissolve tablet is also convenient to take on-the-go, making it easy to maintain your daily B12 intake.

What We Like
Good taste
Quick dissolution
Value for price
Positive health impact
Fast delivery

NUSAVA Vitamin B12 Liquid Drops

NUS-LIQVITB12-DRPS-2PK
2 Fl Oz (Pack of 2)
NUSAVA Vitamin B12 Liquid Drops Cover
(2 Pack) Vitamin B12 and B6 Liquid Drops, B12 Sublingual Vitamin B Complex - B 12 Vitamin 5000mcg - B12 Methylcobalamin for Energy, Brain, and Heart Support with 27,200 mcg, Raspberry, 80 Servings

NUSAVA B12 Drops provide a potent blend of Vitamin B12, B6, B1, Niacin, and Folic Acid to support your body functions. Experience brain support, energy metabolism, heart wellness, and immune support with each sublingual drop. Enjoy rapid absorption by placing the drops under your tongue for 30 seconds. This organic formula is free from fillers, vegan, non-GMO, and gluten-free. If you seek a 5-in-1 B12 complex, try NUSAVA B12 Drops for ultimate benefits.

What We Like
Easy to take
Quick absorption
Increased energy levels
Long-lasting bottle
Pleasant taste
#TOP 10

EZ Melts Dissolvable Vitamin B12 Supplements

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EZ Melts Dissolvable Vitamin B12 Supplements Cover
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 Sublingual Tablets (90 Servings)

Try EZ Melts Dissolvable Vitamin B12 Supplements to improve your overall well-being. With a bioactive form of B-12 vitamin, this vegan supplement supports healthy immune function, promotes mental clarity, and aids the body in breaking down food into energy. The cherry flavor taste is created using plant-derived ingredients, and the tablets dissolve in your mouth for easy absorption. Made in the USA with no artificial colors, flavors, or sweeteners and no pesky irritants like gluten or dairy, you can be confident in consistent quality.

What We Like
Supports healthy immune function and promotes mental clarity
Dissolves in your mouth for easy absorption
No artificial colors, flavors, or sweeteners
Made in the USA with no pesky irritants like gluten or dairy
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Can I take Vitamin B12 and B3 together?

Interactions between your drugs No interactions were found between niacin and Vitamin B12. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

2. Is Vitamin B12 and B3 the same?

Vitamin B3 and B12 are two types of vitamin B complexes. The key difference between vitamin B3 and B12 is that vitamin B3 is important in controlling cholesterol and triglyceride levels in our blood, whereas vitamin B12 is important as a cofactor in DNA synthesis for both fatty acid and amino acid metabolism.

3. What are B3 and B12 good for?

Vitamin B12 helps support normal blood production and vitamin B3 is involved in DNA repair and supports skin health. Vitamins B1, B2 and B6 help support the healthy functioning of the nervous system .

4. Do I need B3 and B12?

Vitamins B-3 and B-12 are members of the B-complex family of vitamins, which both collectively and individually are essential to keep your body functioning at optimal levels.

Editor's Notes

During our b3 vitamin b12 supplement research, we found 24 b3 vitamin b12 supplement products and shortlisted 10 quality products. We collected and analyzed 886,018 customer reviews through our big data system to write the b3 vitamin b12 supplements list. We found that most customers choose b3 vitamin b12 supplements with an average price of $18.07.

The b3 vitamin b12 supplements are available for purchase. We have researched hundreds of brands and picked the top brands of b3 vitamin b12 supplements, including Nature Made, Nature's Bounty, THORNE, Pure Encapsulations, NUSAVA. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.