Best Chondroitin & Glucosamine Combination Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 8, 2025

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Chondroitin and Glucosamine Combination Supplements are a popular choice for those seeking relief from joint pain and stiffness. These supplements are made up of two key ingredients: chondroitin sulfate and glucosamine hydrochloride. Chondroitin helps to reduce inflammation in the joints, while glucosamine helps to rebuild cartilage and reduce joint pain. Together, they work to improve joint mobility and flexibility. These supplements are available in a variety of forms, including capsules, tablets, and powders. They are generally safe for most people to take, but it is always recommended to speak with a healthcare professional before starting any new supplement regimen.

At a Glance: Our Top Picks

Joint Support Supplement with Glucosamine, Chondroitin, MSM, Turmeric and Boswellia - 90 Capsules Cover #TOP 1
Joint Support Supplement with Glucosamine, Chondroitin, MSM, Turmeric and Boswellia - 90 Capsules
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Nature Made Joint Support Supplement Cover #TOP 2
Nature Made Joint Support Supplement
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Doctor's Best Glucosamine Chondroitin Msm Capsules Cover #TOP 3
Doctor's Best Glucosamine Chondroitin Msm Capsules
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Top 10 Chondroitin & Glucosamine Combination Supplements

Joint Support Supplement with Glucosamine, Chondroitin, MSM, Turmeric and Boswellia - 90 Capsules

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Joint Support Supplement with Glucosamine, Chondroitin, MSM, Turmeric and Boswellia - 90 Capsules Cover
Glucosamine Chondroitin MSM and Turmeric Supplement - Joint Support Supplement for Women & Men with Boswellia & Glucosamine Sulfate 1500 mg. Used for Cartilage & Joint Health & Flexibility 90 Capsules

Support your healthy joint function, reduce joint discomfort, and maintain cartilage health with this joint support supplement. The expert formula includes Glucosamine, Chondroitin, MSM, Turmeric, and Boswellia, which work together to provide a solid foundation for joint health and function. The supplement also supports an active lifestyle by increasing joint mobility and reducing discomfort. The capsules are made with globally-sourced, non-GMO, gluten-free, dairy-free, sugar-free, and soy-free ingredients, and come in a convenient flip-top bottle for on-the-go nutrition.

What We Like
Reduces joint discomfort and promotes comfortable movement
Supports cartilage health and joint flexibility
Formulated to support an active lifestyle

Nature Made Joint Support Supplement

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Nature Made Joint Support Supplement Cover
Nature Made Glucosamine Chondroitin Complex with MSM, Dietary Supplement for Joint Support, 120 Caplets, 60 Day Supply

The Nature Made Glucosamine Chondroitin Complex with MSM is a dietary supplement designed to support your joint cartilage, allowing your joints to move smoothly. Each bottle contains 120 caplets, giving you a 60-day supply. To ensure the product's quality, customers must be present during delivery to avoid any damage caused by sunlight or heat. The supplement is gluten-free, contains no synthetic dyes, or artificial flavors. Adults should take two of these caplets daily with water and a meal.

What We Like
Gluten-free
Contains no synthetic dyes or artificial flavors
Designed to support joint cartilage and smooth joint movement
#TOP 3

Doctor's Best Glucosamine Chondroitin Msm Capsules

DRB-00081
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Doctor's Best Glucosamine Chondroitin Msm with OptiMSM Capsules, Supports Healthy Joint Structure, Function & Comfort, Non-GMO, Gluten Free, Soy Free, 240 Count (Pack of 1)

Doctor's Best Joint Support is a dietary supplement that combines glucosamine, chondroitin, and MSM to support healthy joint structure, function, and comfort. Glucosamine helps prevent joint tissue breakdown and associated symptoms such as pain, stiffness, and weakness. Chondroitin absorbs fluid in the bones to keep joints healthy. MSM provides dietary sulfur, which strengthens joint tissues and helps with elasticity. This powerful combination of proven, purified ingredients can improve joint flexibility and protect joint tissue. Doctor's Best Joint Support can also support overall health for hair, skin, and nails.

What We Like
Improves joint flexibility
Supports overall health
Clinically-studied ingredients
#TOP 4

Double Wood Glucosamine Chondroitin Triple Strength

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Glucosamine Chondroitin Triple Strength (1,500mg Glucosamine Sulfate, 1,200mg Chondroitin) 180 Tablets, Two Month Supply (Joint Support Supplement) Gluten Free, Non-GMO by Double Wood

Double Wood Joint Support combines Glucosamine and Chondroitin to provide potential relief for your hips and knees, promoting healthier joints. This supplement features a researched dosage of 1500mg of Glucosamine Sulfate and 1200mg of Chondroitin Sulfate, which may enhance joint health. For pet owners, the tablets can easily be dissolved in water or mixed into dog food, allowing you to support your furry friend’s joint health as well. With its triple strength formula, you can feel confident that you are using a well-studied option for joint support.

What We Like
Supports joint health
Pet-friendly option
Triple strength formula
Easy to consume
#TOP 5

VitaBreeze Glucosamine, Chondroitin, MSM and Turmeric Supplement

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VitaBreeze Glucosamine, Chondroitin, MSM and Turmeric Supplement Cover
VitaBreeze Glucosamine Chondroitin, MSM & Turmeric Dietary Supplement - 248 Capsules

VitaBreeze's Glucosamine, Chondroitin, MSM and Turmeric supplement is a triple strength formula with premium ingredients, including turmeric, that work together to support your body. The small, easy-to-swallow capsules are free of GMOs, binders, fillers, and preservatives. Tested for purity and potency, this supplement is manufactured in an inspected facility following strict GMP guidelines. Take two capsules twice daily to receive a dose of 1500mg Glucosamine sulfate, 1000mg Chondroitin sulfate, 600mg MSM, and 300mg Turmeric.

What We Like
Premium ingredients, including turmeric
Small, easy-to-swallow capsules
No GMOs, binders, fillers, or preservatives
Tested for purity and potency
#TOP 6

Clean Nutraceuticals Joint Support Supplement

Glucosamine Chondroitin MSM
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Clean Nutraceuticals Joint Support Supplement Cover
Clean Nutraceuticals Glucosamine Chondroitin MSM Turmeric Hyaluronic Acid Boswellia Collagen Tart Cherry - Joint Support Supplement Omega 3 Pills Ginger Quercetin Capsules - 120 Count USA

Clean Nutraceuticals Joint Support is an all-in-one supplement designed to enhance your joint health. It combines Glucosamine Sulfate for cartilage repair, Chondroitin Sulfate for improved flexibility, and MSM for effective pain relief. Additionally, it features powerful antioxidant ingredients like Turmeric, Ginger, and Boswellia, which can help reduce inflammation and discomfort in your joints. This supplement is particularly beneficial for those experiencing age-related joint issues. You may start feeling relief quickly, but for optimal long-term results, consistency is key.

What We Like
Comprehensive joint health support
Reduces inflammation and pain
Improves joint flexibility
Contains essential vitamins
#TOP 7

NOW Glucosamine & Chondroitin with MSM, 300 Capsules

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Now Glucosamine & Chondroitin with MSM, 300 Capsules, Joint Health Supplement

NOW Joint Health Supplement is a superior combination of Glucosamine, Chondroitin, and MSM that promotes normal joint mobility and comfort. MSM is a naturally occurring sulfur compound that supports the production of healthy joint structures. This supplement is convenient to take with suggested usage of 3 capsules daily. NOW Joint Health Supplement is better for you because it is not manufactured with common allergens such as wheat, gluten, soy, corn, milk, egg, tree nut, or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens, NOW Joint Health Supplement is a reliable choice for your joint health needs.

What We Like
Superior combination
Promotes normal joint mobility and comfort
Naturally occurring sulfur compound
#TOP 8

Nature's Bounty Joint Health Supplement, 110 Capsules

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Nature's Bounty Joint Health Supplement, 110 Capsules Cover
Nature's Bounty Glucosamine Chondroitin Pills and Dietary Supplement, Support Joint Health, 110 Capsules

Support your joint health with Nature's Bounty Glucosamine Chondroitin Pills and Dietary Supplement. This supplement nourishes your joints and helps maintain healthy cartilage. It contains Vitamin C and Manganese, which work together to support the structural framework of your joints. Plus, it is Non-GMO so you can feel good about what you're putting in your body. Choose this Chondroitin Supplement to keep your joints healthy and strong.

What We Like
Nourishes joints and helps maintain healthy cartilage
Supports the structural framework of joints
Contains Vitamin C and Manganese
Non-GMO
#TOP 9

NATURE TARGET Glucosamine Chondroitin Supplement

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NATURE TARGET Glucosamine Chondroitin Joint Support Supplement - Plus MSM, Collagen, Turmeric, Shellfish Free, Supports Joint, Knees, Cartilage, for Men & Women, 120 Caps

NATURE TARGET Joint Support is a comprehensive formula designed to promote joint health. It combines glucosamine and chondroitin to help repair and protect cartilage, ensuring your joints remain cushioned and supported. The addition of Collagen Type II provides essential components for joint comfort, acting as a natural cushion between bones. Moreover, the blend of MSM, Boswellia, and Turmeric enhances flexibility and reduces stiffness, keeping you active and ready for your day. With Vitamin D3 and K2, this supplement aids calcium absorption and directs it to your bones and joints, promoting overall strength and mobility.

What We Like
Shellfish-free ingredients
Supports joint flexibility
Promotes cartilage health
Enhances bone strength
#TOP 10

KIRKLAND Signature Glucosamine Chondroitin 220 Tablets

KIRKLAND
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KIRKLAND Signature Extra Strength Glucosamine 1500 mg Chondroitin 1200 mg 220 Tablets

KIRKLAND Signature Glucosamine Chondroitin is a dietary supplement that provides joint support and cartilage protection. With 1500 mg of Glucosamine HCI and 1200 mg of Chondroitin Sulfate, this supplement helps lubricate and cushion your joints, reducing discomfort and promoting flexibility. It also aids in protecting your cartilage, preventing further damage and promoting joint health. The product is free from preservatives, gluten, and lactose, making it suitable for individuals with dietary restrictions. Additionally, it is USP Verified, ensuring quality and effectiveness. KIRKLAND Signature Glucosamine Chondroitin is a convenient and reliable choice for maintaining joint health and mobility.

What We Like
Joint support
Cartilage protection
Lubricates and cushions joints
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Frequently Asked Questions (FAQs)

1. Should you take glucosamine and chondroitin together?

Taking glucosamine and chondroitin together may provide some pain relief for osteoarthritis. Glucosamine alone may not be as effective for pain relief unless combined with chondroitin.

2. Who should not take glucosamine & chondroitin?

Glucosamine and chondroitin supplements are not recommended for children, pregnant or nursing women, and women who could become pregnant. This is due to the limited knowledge of their effects on a developing child or baby.

3. What supplements should not be taken with glucosamine chondroitin?

If you are taking the anticoagulant warfarin (Jantoven), it is important to be cautious when using glucosamine and chondroitin. These supplements have the potential to increase the effects of warfarin, increasing the risk of bleeding.

4. Which is better for joints turmeric or glucosamine chondroitin?

Both turmeric and glucosamine chondroitin have their own benefits for joint health. Glucosamine chondroitin is more specifically focused on improving joint health, while turmeric is a more multi-purpose superfood. Both are generally safe for daily supplementation and can improve joint health and flexibility in their own ways.

5. What are the negative side effects of glucosamine chondroitin?

Some possible negative side effects of glucosamine chondroitin supplements include nausea, diarrhea, constipation, stomach pain, gas, bloating, hair loss, and puffy eyelids.

6. Is glucosamine and chondroitin hard on your kidneys?

Taking glucosamine for an extended period of time may lead to acute interstitial nephritis and renal toxicity in some cases. Patients with a history of glucosamine-related products have shown signs of renal failure and high levels of renal and hepatic toxicity.

7. Is Glucosamine Chondroitin hard on your liver?

Clinical trials have not linked glucosamine and chondroitin to liver injury or serum enzyme elevations. Reported cases of clinically apparent liver injury from these supplements are rare and have not been reported in prospective trials.

Editor's Notes

During our chondroitin & glucosamine combination supplement research, we found 24 chondroitin & glucosamine combination supplement products and shortlisted 10 quality products. We collected and analyzed 360,058 customer reviews through our big data system to write the chondroitin & glucosamine combination supplements list. We found that most customers choose chondroitin & glucosamine combination supplements with an average price of $20.93.

The chondroitin & glucosamine combination supplements are available for purchase. We have researched hundreds of brands and picked the top brands of chondroitin & glucosamine combination supplements, including Vimerson Health, Nature Made, Doctor's BEST, Double Wood Supplements, VitaBreeze. The seller of top 1 product has received honest feedback from 2,857 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.