Best Liquid Antidiarrheal Medications of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 4, 2025

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Liquid antidiarrheal medications are a popular over-the-counter solution for those suffering from diarrhea. These medications work by slowing down the movement of the intestines, reducing the frequency of bowel movements and allowing the body to absorb more water and nutrients. Some common active ingredients found in these medications include loperamide and bismuth subsalicylate. It is important to follow the dosage instructions carefully, as overuse of these medications can lead to constipation and other side effects. It is also important to stay hydrated and seek medical attention if diarrhea persists for more than a few days.

At a Glance: Our Top Picks

Imodium A-D Liquid Oral Anti-Diarrheal Medicine Cover #TOP 1
Imodium A-D Liquid Oral Anti-Diarrheal Medicine
ftb score rating icon 9.9
Pepto Bismol Liquid Cover #TOP 2
Pepto Bismol Liquid
ftb score rating icon 9.8
Imodium A-D Children's Liquid Anti-Diarrheal Medicine Cover #TOP 3
Imodium A-D Children's Liquid Anti-Diarrheal Medicine
ftb score rating icon 9.6

Top 10 Liquid Antidiarrheal Medications

#TOP 1

Imodium A-D Liquid Oral Anti-Diarrheal Medicine

300450134080
8 Fl Oz (Pack of 1)
Imodium A-D Liquid Oral Anti-Diarrheal Medicine Cover
Imodium A-D Liquid Anti-Diarrheal Medicine, Loperamide Hydrochloride, Mint, 8 fl. oz

Imodium A-D liquid oral anti-diarrheal medicine comes in an 8-fluid ounce bottle with mint flavor, designed to work with your body to restore its natural rhythm and balance. Its proven formula helps control symptoms of diarrhea for fast, effective relief. It contains 1 mg of loperamide HCl in every 7.5 milliliters to help control symptoms of diarrhea due to acute, active and Traveler's diarrhea. It is easy to take, and it works faster than the leading prescription medication containing diphenoxylate and atropine.

What We Like
Works fast for effective relief
Proven formula helps control symptoms of diarrhea
Easy-to-take liquid formula with a refreshing mint flavor
#TOP 2

Pepto Bismol Liquid

1299292831
Pepto Bismol Liquid Cover
Pepto Bismol Liquid for Nausea, Heartburn, Indigestion, Upset Stomach, and Diarrhea - Fast Relief for 5 Symptoms, Original Flavor, 2x12 oz

Pepto Bismol Relief is a trusted brand that has been providing fast relief for upset stomachs for over 100 years. Its coating action helps to calm the stomach and soothe the digestive system, effectively relieving symptoms such as nausea, heartburn, indigestion, upset stomach, and diarrhea. With Pepto Bismol Relief, you can experience relief from these uncomfortable symptoms, allowing you to get back to your day without interruption. As the #1 pharmacist recommended brand for upset stomachs, you can trust Pepto Bismol Relief to provide high-quality relief that you can count on.

What We Like
Fast relief for 5 symptoms
Trusted brand for over 100 years
Coats and soothes the stomach
#TOP 3

Imodium A-D Children's Liquid Anti-Diarrheal Medicine

300450134448
4 Fl Oz (Pack of 1)
Imodium A-D Children's Liquid Anti-Diarrheal Medicine Cover
Imodium A-D Children's Liquid Anti-Diarrheal Medicine, Loperamide Hydrochloride, Mint, 4 fl. oz

Imodium Children's Liquid is a 4-fluid ounce bottle of anti-diarrheal medicine designed specifically for kids ages 6 and older. With its refreshing mint flavor, this oral medicine helps control and treat diarrhea symptoms, allowing your child to get back to their normal activities. The formula works with your child's body to slow down their system and restore their natural rhythm and balance. Each dose contains 1 milligram of loperamide hydrochloride, providing fast and effective relief. Imodium Children's Liquid is the #1 doctor-recommended brand and is proven to work faster than prescription anti-diarrhea medications. Its easy-to-take liquid formula makes it convenient for children to use.

What We Like
Fast relief
Refreshing mint flavor
Easy-to-take liquid formula
#TOP 4

Amazon Basic Care Anti-Diarrheal Medicine

Amazon Basic Care
W912
Green
8 Fl Oz (Pack of 1)
Amazon Basic Care Anti-Diarrheal Medicine Cover
Amazon Basic Care Loperamide Hydrochloride Oral Solution, 1 mg per 7.5 ml, Anti-Diarrheal Medicine, Anti-Diarrhea Medicine For Kids and Adults 12 Years and Over, Mint, 8 fl oz (Pack of 1)

Amazon Basic Care Anti-Diarrheal Medicine is an effective medication for controlling diarrhea symptoms, including Travelers' Diarrhea. It contains Loperamide Hydrochloride 1 mg per 7.5 mL, and has a gluten-free mint flavor. A convenient dosage cup is included. Diarrhea can cause dehydration, but this medication helps to control diarrhea symptoms.

What We Like
Controls diarrhea symptoms including Travelers' Diarrhea
Mint flavor and gluten-free
Comes with a convenient dosage cup
#TOP 5

Foster & Thrive Stomach Relief Liquid

Foster & Thrive
GU1-527
Foster & Thrive Stomach Relief Liquid Cover
Foster & Thrive Stomach Relief Liquid for Nausea, Heartburn, Indigestion, Upset Stomach, and Diarrhea - Fast Relief for 5 Symptoms, Antidiarrheal, Bismuth Subsalicylate 525 mg, Original, 8 oz

Foster & Thrive Relief offers a comprehensive solution for various digestive issues. It effectively addresses five common symptoms: nausea, heartburn, indigestion, upset stomach, and diarrhea, allowing you to feel better quickly. With a strong dose of 525mg of Bismuth Subsalicylate, it works to soothe your digestive system and restore balance. This fast-acting liquid starts to relieve discomfort almost immediately, making it a reliable choice for those unexpected tummy troubles. Whether you’ve overindulged or are dealing with traveler’s tummy, this versatile formula provides the relief you need to get back on track.

What We Like
Rapid relief for multiple symptoms
Strong Bismuth Subsalicylate dose
Fast-acting liquid formula
Versatile for various digestive issues
Trusted by many households
#TOP 6

GoodSense Anti-Diarrheal Medicine

LP64526
Mint
4 Fl Oz (Pack of 1)
GoodSense Anti-Diarrheal Medicine Cover
GoodSense Anti-Diarrheal Medicine, Loperamide Hydrochloride Oral Solution, 1 mg per 7.5 mL, Mint Flavor, 4 Fluid Ounces

GoodSense Anti-Diarrheal Medicine is an effective solution to control symptoms of diarrhea including travelers' diarrhea. It contains Loperamide Hydrochloride 1 mg per 7.5 mL, an active ingredient that helps control diarrhea. The medicine is gluten-free and mint flavored, and comes with a convenient dosage cup. Diarrhea can cause dehydration, and this medicine can help control the symptoms of diarrhea and prevent dehydration.

What We Like
Contains active ingredient Loperamide Hydrochloride
Mint-flavored and gluten-free
Controls symptoms of diarrhea including travelers' diarrhea
#TOP 7

A+Health Loperamide Hcl 2 Mg Softgels

Amazon Basic Care
LOP24
A+Health Loperamide Hcl 2 Mg Softgels Cover
Amazon Basic Care Loperamide Hcl 2 Mg Softgels, Anti-Diarrheal, Made in USA, 24 Count (Pack of 1)

A+Health Loperamide Softgels are an effective solution for controlling diarrhea. These softgels contain Loperamide Hcl 2mg, which is the active ingredient found in Imodium A-D. They are specially designed to help control the symptoms of diarrhea, including Travelers' Diarrhea. Made in the USA using ingredients from various countries, these liquid-filled capsules are easy to swallow, making them suitable for people who have difficulty swallowing. The softgels are suitable for adults and children 12 years and older, with each pack containing 24 softgels. The directions recommend taking 2 softgels after the first loose stool, followed by 1 softgel after each subsequent loose stool, with a maximum of 4 softgels in 24 hours. Stay hydrated by drinking plenty of clear fluids along with the softgels to alleviate diarrhea effectively.

What We Like
Controls diarrhea
Easy to swallow
Made in the USA
#TOP 8

Pepto Bismol Original Liquid 5 Symptom Relief

E316
Color May Vary
8 Fl Oz (Pack of 1)
Pepto Bismol Original Liquid 5 Symptom Relief Cover
Pepto Bismol Original Liquid 5 Symptom Medicine - Including Upset Stomach and Diarrhea Relief 8 oz (Packaging May Vary)

Pepto Bismol Liquid is designed to relieve five common stomach issues: nausea, heartburn, indigestion, upset stomach, and diarrhea. Its unique coating action works quickly to calm and soothe your digestive system, providing fast relief when you need it most. With over 100 years of trusted performance, this product is the #1 choice among pharmacists for treating upset stomachs. As part of the Procter & Gamble family, Pepto Bismol adheres to high-quality standards, ensuring you receive a reliable solution for your stomach discomfort.

What We Like
Effective multi-symptom relief
Fast-acting coating action
Trusted brand for over 100 years
Pharmacist recommended
#TOP 9

Pepto Bismol 5 Symptom Relief

149010000
4 Fl Oz (Pack of 1)
Pepto Bismol 5 Symptom Relief Cover
Pepto Bismol, 5 Symptom Digestive Relief, Original, 4 fl oz

Pepto Bismol Stomach Relief is designed to tackle five common stomach issues: nausea, heartburn, indigestion, upset stomach, and diarrhea. Its unique coating action helps calm your stomach and soothes your digestive system, providing quick relief just like Pepto Bismol Liquid. With a century of trusted service, you can rely on Pepto Bismol for effective treatment of upset stomachs. As the #1 recommended brand by pharmacists, you can feel confident in its quality and effectiveness for your digestive discomfort.

What We Like
Effective for multiple symptoms
Fast-acting relief
Trusted for over 100 years
Pharmacist recommended
#TOP 10

Kaopectate Multi-Symptom Relief

20053076197079CS
New Version
Kaopectate Multi-Symptom Relief Cover
Kaopectate Multi-Symptom Anti-diarrheal and Upset Stomach Reliever, 28 Count

Kaopectate Relief is a trusted antidiarrheal medication that provides calm, soothing relief for a variety of stomach discomforts. Whether you're dealing with diarrhea, upset stomach, nausea, indigestion, or gas, Kaopectate Relief has you covered. Its convenient caplets offer on-the-go relief, allowing you to find comfort wherever you are. With its targeted formula, Kaopectate Relief targets the source of your symptoms, providing quick and temporary relief from seven types of stomach discomfort. Formulated with Bismuth subsalicylate, a proven antacid ingredient, Kaopectate Relief is a reliable solution for relieving temporary stomach and gastrointestinal discomfort. Try Kaopectate Relief and experience the benefits of its trusted formula for yourself.

What We Like
Calm and soothes upset stomach
Convenient on-the-go relief
Targets the source of symptoms
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What liquid medicine is good for diarrhea?

Two types of meds relieve diarrhea in different ways: Loperamide (Imodium) slows the movement of food through your intestines, which lets your body absorb more liquid. Bismuth subsalicylate (Kaopectate, Pepto-Bismol) balances out how fluid moves through your digestive tract.

2. Does Imodium come in liquid form?

IMODIUM® A-D Anti-Diarrheal Oral Solution (liquid) is the fastest single ingredient OTC medicine to help stop diarrhea, allowing you to get back to doing the things you love. With 1mg of Loperamide HCl per 7.5 mL, this product helps control the symptoms of diarrhea, including Travelers' Diarrhea.

3. Can you buy liquid Imodium over-the-counter?

You can buy loperamide from pharmacies and supermarkets or you can get it on prescription. Loperamide is available to buy without a prescription for: anyone aged 12 and older with short-term diarrhoea.

4. Is Imodium good for liquid diarrhea?

Imodium is often the go-to treatment for diarrhea and traveler's diarrhea. Loperamide, the active ingredient in Imodium, relieves diarrhea symptoms by slowing the digestive system back down to its normal rhythm.

Editor's Notes

During our liquid antidiarrheal medication research, we found 24 liquid antidiarrheal medication products and shortlisted 10 quality products. We collected and analyzed 139,217 customer reviews through our big data system to write the liquid antidiarrheal medications list. We found that most customers choose liquid antidiarrheal medications with an average price of $7.02.

The liquid antidiarrheal medications are available for purchase. We have researched hundreds of brands and picked the top brands of liquid antidiarrheal medications, including TENA, Pepto Bismol, Foster & Thrive, GoodSense, Kaopectate. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.