Best Vitamin B3 (Niacin) Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 10, 2026

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Vitamin B3, also known as niacin, is an essential nutrient that plays a key role in maintaining a healthy metabolism and nervous system. However, some people may not get enough of this important vitamin through their regular diet alone. This is where niacin supplements come in. These supplements can help ensure that individuals are getting enough B3 to support their overall health and wellbeing. Niacin supplements come in various forms, such as capsules, tablets, and powders, and can be found at most health food stores and online retailers. It is always recommended to consult with a healthcare professional before starting any new supplement regimen.

At a Glance: Our Top Picks

TRU NIAGEN Cover #TOP 1
TRU NIAGEN
ftb score rating icon 9.8
Nutricost Niacinamide 500mg Capsules Cover #TOP 2
Nutricost Niacinamide 500mg Capsules
ftb score rating icon 9.7
Nature’s Bounty Niacin 500mg Capsules Cover #TOP 3
Nature’s Bounty Niacin 500mg Capsules
ftb score rating icon 9.5

Top 10 Vitamin B3 (Niacin) Supplements

#TOP 1

TRU NIAGEN

PHTNB001-30-300NSFS
Opaque White
300mg (30 Servings)
TRU NIAGEN Cover
TRU NIAGEN Patented NAD Supplement for Brain Function, Anti Aging & Cell Regeneration, 300mg Niagen, 30 Servings | Supports Cellular Energy, Muscle | Nicotinamide Riboside (NR) Take 1 Daily | 1 Bottle

TRU NIAGEN NAD+ Supplement is a highly efficacious and safe dietary supplement that supports cellular energy metabolism, repair, and vitality. It embodies 20+ years of scientific innovation and is backed by numerous patents and scientific studies. By boosting levels of NAD+ (nicotinamide adenine dinucleotide) in your body, TRU NIAGEN helps to support the optimal functioning of your cells and promotes healthy aging of the heart, brain, and muscles. It also provides comprehensive cellular defense, helping you stay healthy as you age. Thousands of customers have reported overall improvements in their general health and well-being after using TRU NIAGEN. With consistent daily use, TRU NIAGEN is clinically proven to elevate NAD+ levels, making it a scientifically proven and efficient way to support your body's systems and functions as you age.

What We Like
Highly efficacious
Safe
Boosts levels of NAD
#TOP 2

Nutricost Niacinamide 500mg Capsules

NC-B3NIACNMD
Nutricost Niacinamide 500mg Capsules Cover
Nutricost Niacinamide (Vitamin B3) 500mg, 240 Capsules - Non-GMO, Gluten Free, Flush Free Vitamin B3

Nutricost Niacinamide 500mg Capsules provide 240 capsules per bottle, each with 500mg of high-quality vitamin B3 (niacinamide). The product offers the benefits of vitamin B3 without the "niacin flush" effect. It is non-GMO, gluten-free, soy-free, and made in a GMP compliant, FDA registered facility. Nutricost Niacinamide may have a white or blue lid. This product is a great choice for those looking for a vitamin B3 supplement.

What We Like
240 capsules per bottle
500mg of vitamin B3 per capsule
No "niacin flush" effect
Non-GMO, gluten-free, soy-free
Made in a GMP compliant, FDA registered facility
#TOP 3

Nature’s Bounty Niacin 500mg Capsules

Nature’s Bounty Niacin 500mg Capsules Cover
Nature's Bounty Niacin 500mg Flush Free, Cellular Energy Support, Supports Nervous System Health, 120 Capsules

If you're looking for a supplement that offers cellular energy support and supports nervous system health, Nature’s Bounty Niacin 500mg Capsules could be a good option for you. Niacin helps convert food to cellular energy, which fuels your body. The flush-free formula uses Inositol Hexanicotinate, which is less likely to cause skin flushing, and is gluten-free with no artificial flavors or colors. Each pack contains 120 capsules, adults should take one to two capsules daily with a meal. Aside from the product's excellent value, the brand has 50 years of dedication to quality, consistency, and scientific research.

What We Like
Provides cellular energy support and supports nervous system health
Flush-free formula uses Inositol Hexanicotinate, which is less likely to cause skin flushing
Gluten-free with no artificial flavors or colors
Excellent value compared to other top brands
50 years of dedication to quality, consistency, and scientific research
#TOP 4

21st Century Niacinamide 500 mg Prolonged Release Tablets

22550
No Color
21st Century Niacinamide 500 mg Prolonged Release Tablets Cover
21st Century Niacinamide 500 mg Prolonged Release Tablets, 110 Count

The 21st Century Niacinamide 500 mg Prolonged Release Tablets are a great source of Vitamin B-3, which plays a key role in converting food into energy and maintaining normal nerve, skin, and digestive system function. The prolonged release feature allows for slow nutrient release over an extended period of time. The product is gluten-free and does not contain added sugar, salt, yeast, preservatives, artificial flavors or colors. The tablets are manufactured in a cGMP facility under the strictest quality standards for potency and purity.

What We Like
Good source of Vitamin B-3 without the flushing effect associated with niacin
Prolonged release feature allows for slow nutrient release over an extended period of time
Gluten-free and does not contain added sugar, salt, yeast, preservatives, artificial flavors or colors
#TOP 5

Nutricost Niacin 500mg Capsules - Non-GMO, Gluten Free

ZL08078
Nutricost Niacin 500mg Capsules - Non-GMO, Gluten Free Cover
Nutricost Niacin (Vitamin B3) 500mg, 240 Capsules - with Flushing, Non-GMO, Gluten Free

Get your daily dose of Vitamin B3 with Nutricost Niacin 500mg Capsules. Each capsule contains a potent 500mg of Niacin, which is essential for maintaining healthy skin, digestion, and nervous system. However, the product warns that it will likely cause a "Niacin Flush," which can be reduced by consuming it with food. The 240 immediate-release capsules are non-GMO, gluten-free, and 3rd party tested, ensuring their quality and safety. Moreover, they are made in a GMP compliant, FDA registered facility, which adds to their reliability and effectiveness.

What We Like
Potent 500mg of Niacin per capsule
240 immediate-release capsules per bottle
Non-GMO, gluten-free, and 3rd party tested
Made in a GMP compliant, FDA registered facility
#TOP 6

Thorne Niacinamide - 500mg Niacin - 180 Capsules

B131
Thorne Niacinamide - 500mg Niacin - 180 Capsules Cover
THORNE - Niacinamide - 500mg Niacin - Non-Flushing Form of Vitamin B3 - Support Joint Health, Skin Health & Restful Sleep* - Gluten-Free - 180 Capsules

Thorne Niacinamide is a non-flushing form of vitamin B3 that supports joint health, skin health, and restful sleep. This product is gluten-free and free from other major allergens including soy, dairy, shellfish, and fish. Thorne is committed to providing pure, science-backed products that have earned the trust of healthcare professionals and families around the world.

What We Like
Non-flushing form of vitamin B3
Supports restful sleep and joint health
Gluten-free and free from other major allergens
#TOP 7

Heliocare Advanced Skin Health Supplement

0481-08
Heliocare Advanced Skin Health Supplement Cover
Heliocare Advanced Niacin B3 Supplement: Fernblock PLE Extract 240mg Per Serving - Supports Skin Cell Health W/Antioxidant Rich Vitamin B3 Niacin 500 mg - 120 Vegan Capsules

Heliocare Advanced Nicotinamide B3 Supplement is a skin care dietary supplement that can be taken daily. The advanced formula includes Nicotinamide (vitamin B3) non-flush form to help improve the appearance of skin. The Fernblock PLE technology helps against the harmful effects of free radicals. It is a Vegan and gluten-free formula derived from nature with no artificial dyes or fillers. Adults may take 2 Heliocare Advanced capsules daily or as directed by your physician. Heliocare Advanced is not a replacement for topical sunscreen.

What We Like
Advanced formula to help improve the appearance of skin
Antioxidant support with Fernblock PLE technology to help against the harmful effects of free radicals
Vegan and gluten-free formula derived from nature with no artificial dyes or fillers
#TOP 8

NOW Foods Niacinamide 500mg Capsules

NOW755
No Color
NOW Foods Niacinamide 500mg Capsules Cover
NOW Niacinamide 500mg,100 Capsules

NOW Niacinamide Capsules by NOW Foods offer a convenient way to support your health with vitamin B3, also known as niacinamide. Each capsule delivers a 500mg dose, helping you maintain healthy skin, improve energy metabolism, and support your nervous system. As a B complex vitamin, niacinamide plays an important role in converting food into energy, making it easier for you to stay active throughout the day. With a simple serving size of one capsule, you can easily include this supplement in your daily routine without hassle.

What We Like
High-dose niacinamide
B complex vitamin support
Easy one-capsule serving
Supports energy metabolism
#TOP 9

Nutricost Niacin 100mg Capsules

NTC-20084
Nutricost Niacin 100mg Capsules Cover
Nutricost Niacin (Vitamin B3) 100mg, 240 Capsules - with Flushing, Non-GMO, Gluten Free

Nutricost Niacin Capsules offer 100mg of Vitamin B3 per capsule. Be aware that it may cause a "Niacin Flush," especially on an empty stomach. Each bottle contains 240 immediate-release capsules. The product is Non-GMO, Gluten Free, and 3rd Party Tested. It is manufactured in a GMP Compliant, FDA Registered Facility. With these capsules, you can easily incorporate Vitamin B3 into your daily routine, supporting your overall health and well-being.

What We Like
100mg Vitamin B3 per capsule
240 immediate-release capsules
Non-GMO, Gluten Free
#TOP 10

Toniiq Liposomal NAD+ Resveratrol 1500mg

NAD supplement
Toniiq Liposomal NAD+ Resveratrol 1500mg Cover
Toniiq Liposomal NAD+ and Resveratrol Supplement - 1500mg Ultra High Strength NAD Supplement - Clinically Studied Ingredients with Patented RiaGev-WS™, Resveratrol, and Niacin - 60 Capsules

The Toniiq NAD+ Resveratrol supplement offers a powerful 1,500 mg blend per serving, including 500 mg of pure NAD+, which is among the highest doses you can find. This means you get a strong boost to support your body's natural energy and cell repair processes. Its unique formula combines NAD+ with Resveratrol, Niacin, and the patented RiaGev-WS, providing a well-rounded approach to enhancing your NAD+ levels. The RiaGev-WS ingredient is clinically proven in a rigorous trial to effectively increase NAD+. Plus, every batch is third-party tested for purity and quality, ensuring you get a safe and potent product.

What We Like
High NAD+ dose
Unique ingredient blend
Clinically proven formula
Third-party tested
Buying Guide Image

Vitamin B3 (Niacin) Supplements Buying Guide: What You Need to Know

What is Vitamin B3 (Niacin)?

Vitamin B3, also known as niacin, is an essential nutrient that plays a crucial role in maintaining good health. It is involved in many of the body's metabolic processes, including the production of energy, the synthesis of hormones, and the detoxification of harmful substances.

Why do we need Vitamin B3 (Niacin)?

The human body cannot produce vitamin B3 on its own, so it must be obtained from dietary sources or supplements. Good sources of niacin include meat, fish, poultry, eggs, and dairy products. However, some people may not get enough niacin from their diet, especially if they have certain medical conditions or follow a vegetarian or vegan diet. In these cases, taking a niacin supplement may be beneficial.

What are the benefits of Vitamin B3 (Niacin)?

Vitamin B3 has many potential health benefits, including:

  • Reducing cholesterol levels: Niacin has been shown to increase the levels of "good" cholesterol (HDL) in the blood, while decreasing the levels of "bad" cholesterol (LDL) and triglycerides. This can help prevent heart disease and stroke.

  • Improving circulation: Niacin helps dilate blood vessels, which can improve blood flow and reduce the risk of blood clots.

  • Supporting the nervous system: Vitamin B3 is involved in the production of neurotransmitters, which are chemicals that transmit signals in the nervous system. It may help with conditions such as anxiety and depression.

  • Boosting energy levels: Niacin is involved in the production of energy from the food we eat, so taking a supplement may help improve energy levels.

  • Protecting against cognitive decline: Some studies have suggested that niacin may help protect against cognitive decline and Alzheimer's disease.

How to choose Vitamin B3 (Niacin) Supplements?

When choosing a niacin supplement, there are a few things to consider:

  • Dosage: The recommended daily allowance (RDA) for niacin varies depending on age and gender. Most adults need between 14 and 16 milligrams per day. It's important to choose a supplement that provides the right dosage for your needs.

  • Form: Niacin supplements are available in several different forms, including tablets, capsules, and liquids. The form you choose will depend on your personal preference and any other medications you are taking. For example, if you have difficulty swallowing pills, a liquid supplement may be a better option.

  • Timing: Niacin supplements can cause a temporary flushing sensation, which can be uncomfortable for some people. To minimize this side effect, it's best to take the supplement with food and avoid taking it at bedtime.

  • Quality: As with any supplement, it's important to choose a product that is high quality and has been manufactured to strict standards. Look for supplements that have been certified by a reputable organization, such as the United States Pharmacopeia (USP) or the National Sanitation Foundation (NSF).

Conclusion

Vitamin B3, or niacin, is an essential nutrient that plays a crucial role in many of the body's metabolic processes. While it can be obtained from dietary sources, some people may need to take a supplement to ensure they get enough. When choosing a niacin supplement, consider the dosage, form, timing, and quality of the product.

Frequently Asked Questions (FAQs)

1. What does vitamin B3 niacin do for the body?

Vitamin B3, also known as niacin, is essential for the body as it helps convert food into energy. It plays a role in maintaining a healthy nervous system, digestive system, and skin. While some people may take niacin as part of a multivitamin, most individuals can obtain sufficient amounts of niacin from their diet.

2. Is it safe to take B3 everyday?

Taking high doses of B3, beyond the recommended daily allowance (RDA), can be toxic and should only be done under a doctor's supervision. While very high doses of niacin have been studied for certain conditions, it is generally not recommended to exceed the RDA without medical guidance.

Niacin therapy has been associated with various serious side effects, including skin rashes, gastrointestinal problems, complications in managing pre-existing diabetes, and an increased risk of developing diabetes. Due to these potential risks, niacin may no longer be recommended for certain individuals.

4. How much niacin B3 should you take daily?

The recommended daily allowance (RDA) for niacin is measured in milligrams (mg) of niacin equivalents (NE). The RDA for adults is 16 mg NE for men, 14 mg NE for women, 18 mg NE for pregnant women, and 17 mg NE for lactating women. It's important to follow these guidelines and not exceed the recommended dosage unless advised by a healthcare professional.

5. What are the symptoms of a B3 deficiency?

A severe deficiency of vitamin B3 or niacin can lead to a condition called pellagra. Symptoms of pellagra include a dark, scaly rash on sun-exposed skin areas, redness of the tongue, constipation or diarrhea, and even depression and headache. It's important to ensure an adequate intake of niacin to prevent these deficiencies and associated symptoms.

Editor's Notes

During our vitamin b3 (niacin) supplement research, we found 24 vitamin b3 (niacin) supplement products and shortlisted 10 quality products. We collected and analyzed 302,391 customer reviews through our big data system to write the vitamin b3 (niacin) supplements list. We found that most customers choose vitamin b3 (niacin) supplements with an average price of $16.36.

The vitamin b3 (niacin) supplements are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b3 (niacin) supplements, including TRU NIAGEN, Nutricost, Nature's Bounty, 21st Century, THORNE. The seller of top 1 product has received honest feedback from 520 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.