Best L-Lysine Supplement Tablets of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 13, 2026

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L-Lysine Supplement Tablets are a popular choice for individuals looking to support their immune system and maintain healthy skin and tissue. These tablets contain a high potency dose of L-Lysine, an essential amino acid that the body cannot produce on its own. L-Lysine is known for its ability to support the production of collagen, which is important for maintaining healthy skin, bones, and muscles. Additionally, L-Lysine has been shown to support the immune system, especially during times of stress. These supplement tablets are easy to take and can be incorporated into a daily routine to support overall health and wellness.

At a Glance: Our Top Picks

NOW Supplements L-Lysine Hydrochloride 100 Tablets Cover #TOP 1
NOW Supplements L-Lysine Hydrochloride 100 Tablets
ftb score rating icon 9.8
Nature Made L-Lysine 1000mg Supplement Cover #TOP 2
Nature Made L-Lysine 1000mg Supplement
ftb score rating icon 9.7
Quantum Health SuperLysine+ Advanced Formula Immune Support Supplement|180 Tablets Cover #TOP 3
Quantum Health SuperLysine+ Advanced Formula Immune Support Supplement|180 Tablets
ftb score rating icon 9.5

Top 10 L-Lysine Supplement Tablets

NOW Supplements L-Lysine Hydrochloride 100 Tablets

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Cream
NOW Supplements L-Lysine Hydrochloride 100 Tablets Cover
NOW Foods Supplements, (L-Lysine Hydrochloride) 1,000 mg, Double Strength, Amino Acid, 100 Tablets

Looking for a vegan-friendly L-Lysine supplement? NOW Supplements L-Lysine Hydrochloride provides you with a double-strength essential amino acid that supports collagen synthesis and is required for the maintenance of structural proteins such as collagen and elastin. With certifications such as non-GMO, nut-free, soy-free, and kosher, this product provides you with the necessary daily dose of Lysine. This GMP quality assured product is manufactured in the USA by a family-owned and operated company since 1968.

What We Like
Immune system support
Cold sore prevention
Clearer, healthier skin
Easy on stomach
High potency and value
#TOP 2

Nature Made L-Lysine 1000mg Supplement

Nature Made L-Lysine 1000mg Supplement Cover
Nature Made L-Lysine 1000 mg, Dietary Supplement, 60 Tablets, 60 Day Supply

Nature Made L-Lysine 1000mg Supplement is a dietary supplement that helps the body synthesize protein with just one convenient dose per day. This supplement provides 1000mg of one of the nine essential amino acids. L-Lysine is necessary for certain bodily functions and manufacturing body proteins. It aids in calcium absorption and collagen formation. Carnitine, an important energy-producing compound, is synthesized from lysine. Carnitine may help the body utilize fat more efficiently, and therefore may streamline the process of energy production. Adults take one tablet daily with water and a meal. Nature Made supplements are quality you can trust.

What We Like
Cold sore prevention
Immune system support
High-quality ingredients
Good value for money
No unpleasant aftertaste

Quantum Health SuperLysine+ Advanced Formula Immune Support Supplement|180 Tablets

F-SL180
Speckled Sand
Quantum Health SuperLysine+ Advanced Formula Immune Support Supplement|180 Tablets Cover
Quantum Health SuperLysine+ Advanced Formula Immune Support Supplement Lysine 1500 mg, Vitamin C Echinacea Licorice Bee Propolis & Odorless Garlic Daily Wellness Blend for Women & Men - 180 Tablets

Quantum Health SuperLysine+ Advanced Formula Immune Support Supplement is a powerful immune booster with ingredients like Vitamin C, Echinacea, Licorice, Propolis, and Odorless Garlic. It promotes collagen growth, supports lip health, and provides antioxidant support. The specially coated tablets are easy to swallow, and each bottle contains a full 60-day supply. It's an award-winning lysine power formula from a trusted leader in the natural products industry.

What We Like
Immune system support
Prevents cold sores
Reduces canker sores
Odorless or minimal garlic smell
Easy to swallow tablets

Solgar L-Lysine 1000mg Tablets, 250 ct

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Solgar L-Lysine 1000mg Tablets, 250 ct Cover
Solgar L-Lysine 1000 mg, 250 Tablets - Enhanced Absorption and Assimilation - Promotes Integrity of Skin and Lips - Collagen Support - Amino Acids - Non-GMO, Vegan, Gluten Free - 250 Servings

The Solgar L-Lysine 1000mg Tablets are an easy-to-take dietary supplement that promotes the integrity of skin and lips, and supports collagen production. The tablets contain Free Form L-Lysine for optimal absorption and assimilation, and are suitable for vegans, non-GMO, and certified gluten-free. L-Lysine is an essential amino acid that helps to maintain healthy skin tissue. This supplement is ideal for adults looking to support a healthy complexion and skin tissue.

What We Like
Effective immune support
Easy to absorb
High potency dosage
Long-lasting value bottle
Allergen-free formula

NOW L-Lysine Amino Acid 500mg, 250 Tablets

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NOW L-Lysine Amino Acid 500mg, 250 Tablets Cover
NOW Supplements, L-Lysine (L-Lysine Hydrochloride) 500 mg, Amino Acid, 250 Tablets

Get your essential amino acid L-Lysine from NOW Supplements, which cannot be produced by your body and must be obtained through your diet or supplementation. It supports the production of protein, hormones, enzymes, antibodies, and carnitine, as well as collagen which forms connective tissue such as skin, tendon, and bone. In addition, L-Lysine plays a crucial role in calcium absorption. This product is non-GMO, dairy-free, egg-free, gluten-free, nut-free, soy-free, vegan/vegetarian, and has been quality assured by GMP. It is packaged in the USA by a family owned and operated company since 1968.

What We Like
Cold sore prevention
Faster healing for mouth sores
Helps chapped and cracked lips
Easy-to-swallow 500mg size
No side effects noticed
#TOP 6

Best Naturals L-Lysine 1000mg - 180 Tablets

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Best Naturals L-Lysine 1000mg - 180 Tablets Cover
Best Naturals L-Lysine 1000mg 180 Tablets - Double Strength Lysine for stronger immune health & cold sores

Best Naturals L-Lysine is a double-strength supplement that promotes stronger immune health and helps with cold sores. The product is third-party lab tested for purity and quality, and each tablet contains 1000mg of L-Lysine HCL. It is non-GMO, gluten-free, and contains no artificial color, flavor, or sweetener, preservatives, sugar, milk, corn, soy, egg, lactose, gluten, wheat, yeast, fish or sodium. This product is proudly made in USA, in a GMP compliant and FDA registered facility.

What We Like
Fast cold sore relief
Easy daily supplement
Large bottle, good value
No taste
Gentle on stomach
#TOP 7

Amazon Elements Lysine Complex with Vitamin C

Amazon Elements
B075DKYD8R
Amazon Elements Lysine Complex with Vitamin C Cover
Amazon Elements Lysine Complex, with Vitamin C, Vegetarian, Immune Support, 195 Tablets (Packaging may vary)

The Amazon Elements Lysine Complex with Vitamin C is a dietary supplement designed to support your immune health. Each serving contains 1500mg L-Lysine and 100mg Vitamin C, as well as echinacea and other harvested ingredients to promote overall wellness. The supplement is vegetarian, gluten-free, and free from artificial colors, flavors, and chemical preservatives. The tablets are made in a GMP facility in the USA and come in a 195 count bottle, providing a 2-month supply. Customers can reorder using Alexa voice shopping.

What We Like
Contains 1500mg L-Lysine and 100mg Vitamin C per serving
Includes echinacea and other harvested ingredients to promote overall wellness
Vegetarian, gluten-free, and free from artificial colors, flavors, and chemical preservatives
#TOP 8

Bronson L-Lysine Extra Strength 1000 MG

1193-100
Bronson L-Lysine Extra Strength 1000 MG Cover
Bronson L-Lysine Extra Strength 1000 MG per Tablet High Potency, Immune Support & Supports Collagen Synthesis, Non-GMO, 100 Vegetarian Tablets

Bronson L-Lysine Extra Strength provides extra strength vegetarian tablets with 1000 MG of high-quality L-Lysine, which helps to support a healthy immune system and promote collagen synthesis. It is laboratory tested GMO-Free, Gluten-Free and Soy-Free. The product is manufactured in-house by trained professionals in a state-of-the-art facility in Hauppauge, New York, and subject to rigorous cGMP Certified New York Facility regulations to ensure purity, potency, and integrity. Bronson Vitamins have been trusted since 1960 by top medical professionals.

What We Like
Provides 1000 MG of high-quality L-Lysine per vegetarian tablet
Helps to support a healthy immune system and promote collagen synthesis
Laboratory tested GMO-Free, Gluten-Free and Soy-Free
Manufactured in-house by trained professionals in a state-of-the-art facility in Hauppauge, New York
Subject to rigorous cGMP Certified New York Facility regulations to ensure purity, potency, and integrity
#TOP 9

Lyranda Lysine Cold Sore Chewables

Lyranda
Lyranda Lysine Cold Sore Chewables Cover
Lyranda® - Lysine Cold Sore Treatment - Chewable L-Lysine Tablets - Faster Absorption and Better Hygiene

The Lyranda Lysine Chewables offer a simple way to support your immune system and help manage cold sores. These chewable tablets are easy to take on the go, making it convenient to get your 1000mg dose anytime without hassle. Because they are chewable, they absorb faster than creams or capsules, helping you see quicker results. Plus, they are made from high-quality, non-GMO ingredients and are free from gluten and lactose, so you can feel good about what you’re putting in your body. This product is designed to be both effective and easy to use, fitting smoothly into your daily routine.

What We Like
Fast absorption
Easy chewable tablets
Supports immune health
Gluten- and lactose-free
#TOP 10

Best Naturals L-Lysine 500 mg 250 Tablets

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Best Naturals L-Lysine 500 mg 250 Tablets Cover
Best Naturals L-Lysine 500 mg 250 Tablets

Best Naturals L-Lysine is a non-GMO and gluten-free dietary supplement that comes with 250 tablets per bottle. Each tablet contains 500 mg of L-Lysine HCL, which is 3rd party lab tested for purity and quality. This product is proudly made in the USA in a GMP compliant, FDA registered facility. Best Naturals L-Lysine does not contain any artificial color, flavor, or sweetener, preservatives, sugar, milk, corn, soy, egg, lactose, gluten, wheat, yeast, fish, or sodium. L-Lysine is an essential amino acid that can help support a healthy immune system, promote calcium absorption, and assist in collagen formation. Taking Best Naturals L-Lysine can be beneficial for individuals who are looking to support their overall well-being and maintain a healthy lifestyle.

What We Like
Non-GMO
Gluten-free
3rd party lab tested
Made in USA
No artificial additives
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is L lysine tablets good for?

Lysine is one of the essential amino acids, which are those that the body cannot make and that people need to obtain from dietary sources. Possible health benefits of lysine and lysine supplements include improving cold sores, reducing blood pressure, and preventing the symptoms of lysine deficiency.

2. What is the best form of L lysine to take?

Best Lysine Supplements. Best Powder: BulkSupplements Lysine Powder.Best Capsule: NOW Foods Lysine Capsule.Most Unique Formula: Quantum Health Super Lysine+Best For Vegans: Superior Labs L-Lysine.

3. What does L lysine do to viruses?

We found that lysine and its ester derivative can efficiently block infection of both viruses in vitro. Furthermore, the arginine ester derivative caused a significant boost in virus infection.

4. How much L lysine should you take a day?

The recommended dosage of L lysine is 500mg 2-3 times daily. In conjunction with taking Lysine, you should avoid a diet high in Arginine containing foods such as chocolate, nuts and dairy.

Editor's Notes

During our l-lysine supplement tablet research, we found 24 l-lysine supplement tablet products and shortlisted 10 quality products. We collected and analyzed 360,153 customer reviews through our big data system to write the l-lysine supplement tablets list. We found that most customers choose l-lysine supplement tablets with an average price of $13.86.

The l-lysine supplement tablets are available for purchase. We have researched hundreds of brands and picked the top brands of l-lysine supplement tablets, including NOW Foods, Nature Made, Quantum, Solgar, Best Naturals. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.