Best Alpha Lipoic Acid Supplements of 2025

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Elisa Drew
Last Updated: Jan 16, 2025

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Alpha Lipoic Acid Supplements are a popular type of dietary supplement that are known for their potential health benefits. These supplements are often taken by individuals looking to support their overall health and well-being, as they are believed to have antioxidant properties that can help protect cells from damage caused by free radicals. In addition, Alpha Lipoic Acid Supplements are also thought to support healthy blood sugar levels and improve nerve function. They are available in various forms, including capsules, tablets, and powders, and can be found at most health food stores and online retailers.

At a Glance: Our Top Picks

Nutricost Alpha Lipoic Acid: 240 Capsules Cover #TOP 1
Nutricost Alpha Lipoic Acid: 240 Capsules
ftb score rating icon 9.8
NOW Supplements Alpha Lipoic Acid Cover #TOP 2
NOW Supplements Alpha Lipoic Acid
ftb score rating icon 9.7
NUTRAHARMONY Alpha Lipoic Acid 600mg Cover #TOP 3
NUTRAHARMONY Alpha Lipoic Acid 600mg
ftb score rating icon 9.5

Top 10 Alpha Lipoic Acid Supplements

#TOP 1

Nutricost Alpha Lipoic Acid: 240 Capsules

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Nutricost Alpha Lipoic Acid: 240 Capsules Cover
Nutricost Alpha Lipoic Acid 600mg Per Serving, 240 Capsules - Gluten Free, Vegetarian Capsules, Soy Free & Non-GMO

Nutricost Alpha Lipoic Acid is a potent supplement that provides 600mg of Alpha Lipoic Acid per serving. It is Non-GMO, Gluten Free, Soy Free, Vegetarian Friendly, and 3rd Party Tested. It is designed to help with inflammation management and is suitable for adults. It comes in a 240 count bottle.

What We Like
High potency per capsule
Easy to swallow
Affordable pricing
Supports overall well-being
What We Don't Like
Mild stomach discomfort
Limited ingredient transparency
#TOP 2

NOW Supplements Alpha Lipoic Acid

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NOW Supplements Alpha Lipoic Acid Cover
NOW Foods Supplements, Alpha Lipoic Acid 600 mg with Grape Seed Extract & Bioperine®, Extra Strength, 120 Veg Capsules

NOW Supplements Alpha Lipoic Acid 600 mg with Grape Seed Extract & Bioperine® is a vegan-based, extra strength supplement that helps support heart health and metabolism management. It is certified Kosher, Dairy Free, Egg Free, Gluten Free, Nut Free, and Soy Free, and is packaged in the USA by a family owned and operated company since 1968. Customers have reported positive results with nerve pain, diabetes, and lower back nerve damage.

What We Like
Effective for restless legs
Reduces lower back pain
Improves alcohol tolerance
Fast delivery
Positive health benefits
What We Don't Like
Small bottle size
Initial unpleasant urine smell
#TOP 3

NUTRAHARMONY Alpha Lipoic Acid 600mg

NUTRAHARMONY Alpha Lipoic Acid 600mg Cover
Alpha Lipoic Acid 600mg - ALA Supplement Antioxidant for Nerve, Energy & Metabolism Support - Extra Strength with Benfotiamine, Vitamins B1 & B12 - Lab Tested, NON-GMO & Vegan - 120 Capsules, 2 Month

NUTRAHARMONY ALA Supplement offers a powerful 600mg of alpha-lipoic acid to enhance your body's antioxidant defenses and support overall health. This supplement features a unique blend that includes Benfotiamine along with vitamins B1 and B12, which promotes nerve health and boosts energy metabolism. By maintaining thiamine levels, it helps ensure your nerves, muscles, and heart function properly. Additionally, this antioxidant-rich formula aids in enhancing your energy, focus, and mood, providing valuable support for cognitive functions. With its high-quality ingredients, you can trust this product to deliver significant health benefits.

What We Like
Effective for numbness and tingling
Cost-effective compared to doctor’s office
High-quality ingredients
Convenient capsule size
Well-regarded brand
What We Don't Like
Misleading dosage information
Two pills needed for full dosage
#TOP 4

Alpha Lipoic Acid 600mg by Horbaach

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Alpha Lipoic Acid 600mg by Horbaach Cover
Horbäach Alpha Lipoic Acid 600mg | 240 Capsules | with Biotin Optimizer | Non-GMO and Gluten Free Supplement

Alpha Lipoic Acid 600mg by Horbaach is a scientifically formulated supplement that contains 600 mg of ALA and 999 mcg of Biotin per serving. It is Non-GMO and Gluten Free, and is backed by Horbaach's commitment to purity and potency. Customers have found it to be helpful for neuropathy and toe pain, and have noted its powerful antioxidant properties.

What We Like
Third-party tested quality
Effective for energy levels
Great value for 600mg
Helpful for body pain
What We Don't Like
Labeling confusion on dosage
Possible acid reflux issue
#TOP 5

Thorne Alpha-Lipoic Acid - 300 mg - 60 Capsules

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Thorne Alpha-Lipoic Acid - 300 mg - 60 Capsules Cover
THORNE Alpha-Lipoic Acid - 300 mg - Supplement Liver Detox, Antioxidant Support, Nerve Health and Mental Sharpness - 60 Capsules

Thorne Alpha-Lipoic Acid is a dietary supplement that supports nerve health, helps maintain mental sharpness, and promotes liver health. It also has important nerve protective effects. This supplement is made from the purest sources worldwide and does not contain gluten, GMOs, artificial preservatives, or sweeteners. Thorne is a trusted brand by health professionals and U.S. Olympic teams. Thorne Alpha-Lipoic Acid can benefit you by protecting your nerves, improving mental clarity, supporting liver function, and promoting overall health.

What We Like
Supports liver detox
Boosts antioxidant levels
Improves energy
Easy to take capsules
Trusted brand quality
What We Don't Like
Peculiar taste
Urine odor changes
#TOP 6

Sundown Super Alpha Lipoic Acid 600 mg

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Sundown Super Alpha Lipoic Acid 600 mg Cover
Sundown Alpha Lipoic Acid 600mg, Supports Antioxidant Health, Dietary Supplement, 60 Capsules

Sundown Super Alpha Lipoic Acid 600 mg is a dietary supplement that helps support sugar metabolism, often called the universal antioxidant, and supports a healthy nervous system. It is Non-GMO, free of gluten, dairy, and artificial flavors, and comes in a 60 capsule bottle. Customers report that it helps reduce discomfort in feet within one week and is strong enough that you do not have to take it over and over through the day.

What We Like
Effective for neuropathy relief
High-quality product
Good daily supplement
Recommended by healthcare professionals
Fast delivery from Amazon
What We Don't Like
Large capsule size
Lingering bad taste
#TOP 7

Carlyle Alpha Lipoic Acid 600mg

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Carlyle Alpha Lipoic Acid 600mg Cover
Carlyle Alpha Lipoic Acid 600mg | Plus Biotin Optimizer | 90 Capsules | Non-GMO & Gluten Free Supplement

Carlyle Alpha Lipoic Acid is a premium supplement that combines the power of Alpha Lipoic Acid (ALA) and Biotin to support your overall health. ALA is known as the "universal antioxidant" and acts as a potent free radical scavenger, protecting your cells from oxidative stress. With 600mg of ALA and 999mg of Biotin per serving, this advanced formula provides optimal support for your body. The quick release capsules ensure fast absorption, allowing you to enjoy the benefits of these powerful ingredients. Carlyle is a trusted brand that is committed to providing high-quality supplements to help you live a healthy life. With Carlyle Alpha Lipoic Acid, you can naturally support your wellness journey.

What We Like
Easy to swallow
No aftertaste
Good for liver health
Affordable price
Fast shipping
What We Don't Like
May cause stomach upset
#TOP 8

Superior Labs Alpha Lipoic Acid - Pure Non-GMO ALA 600mg

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Superior Labs Alpha Lipoic Acid - Pure Non-GMO ALA 600mg Cover
Superior Labs Alpha Lipoic Acid - Pure Non-GMO ALA 600mg (4 Month Supply) 120 Servings - Zero Synthetic Additives - Supports Healthy Aging, Nerve Health, Tingling Feet, Hands & Overall Wellbeing

Superior Labs Alpha Lipoic Acid is a powerful anti-aging antioxidant that helps promote healthy nerve function, tingling hands, feet, limbs, and overall wellbeing. Each serving contains 600mg of pure ALA in a vegetable capsule for superior absorption. All products are produced in 3rd party certified NSF certified facilities and are free of synthetic additives, fillers, heavy metals, and adulterants. Customers have reported significant relief from chronic pain due to idiopathic peripheral neuropathy, as well as relief from nerve pain and sugar spikes after meals.

What We Like
Improved kidney/liver readings
High-quality formulation
Made in the USA
Informative packaging
Effective dosage of ALA
What We Don't Like
Less effective for some users
Mix of R and S type ALA
#TOP 9

Pure Encapsulations Alpha Lipoic Acid 600 mg

Pure Encapsulations Alpha Lipoic Acid 600 mg Cover
Pure Encapsulations Alpha Lipoic Acid 600 mg - ALA Supplement for Liver Support, Antioxidants, Nerve Health, Cardiovascular Health & Carbohydrate Support - Premium Alpha Lipoic Acid - 60 Capsules

Pure Encapsulations Alpha Lipoic Acid 600 mg is a dietary supplement that supports cellular energy, nervous system, and carbohydrate metabolism. It is made with premium ingredients that are tested for their potency and purity. It is also free from common allergens and unnecessary additives.

What We Like
Effective pain relief
Improves blood glucose levels
Trusted brand integrity
Good value for price
Supports nerve regeneration
What We Don't Like
Capsules are somewhat large
Urine odor may be surprising
#TOP 10

Vitamatic Alpha Lipoic Acid 600mg

Vitamatic Alpha Lipoic Acid 600mg Cover
Vitamatic Alpha Lipoic Acid (ALA) 600mg Per Serving - 240 Vegetable Capsules - 120 Servings - Non-GMO & Gluten Free

Vitamatic ALA Supplement offers a powerful dose of 600mg of alpha lipoic acid in each serving, acting as a strong antioxidant to help your body combat free radicals. It supports nerve health, ensuring effective nerve signaling and function, which can be crucial for overall well-being. Additionally, this supplement aids in energy production by facilitating cellular metabolism, helping you feel more energized throughout the day. Lastly, it promotes skin health by protecting collagen and elastin, contributing to a smoother and more youthful appearance. This product is designed to enhance your health from multiple angles.

What We Like
Excellent health benefits
Reasonably priced
Quick delivery
Well-packaged
Effective for diabetic neuropathy
What We Don't Like
Time needed for effectiveness
Buying Guide Image

The Right Alpha Lipoic Acid Supplements for You

Introduction to Alpha Lipoic Acid

Alpha lipoic acid (ALA) is a naturally occurring compound that is produced by the human body. It is an antioxidant that helps to protect cells from damage and is involved in energy production. ALA is found in small amounts in a variety of foods, including red meat, broccoli, and spinach. In supplement form, ALA is often used to treat a variety of health conditions, including diabetes and liver disease.

Choosing the Right ALA Supplement

When choosing an ALA supplement, it's important to consider a few key factors. Here are some things to consider:

  1. Quality: As with any dietary supplement, it's important to choose a high-quality product. Look for supplements that are made by reputable manufacturers and are certified by independent organizations such as the US Pharmacopeia or ConsumerLab.

  2. Dosage: ALA supplements come in a variety of dosages, from as little as 50mg to as much as 600mg. The appropriate dosage for you will depend on your health condition and your doctor's recommendations. It's important to follow the dosage instructions on the label carefully and not exceed the recommended dose.

  3. Form: ALA supplements are available in a variety of forms, including capsules, tablets, and powders. The form you choose will depend on your personal preferences and your doctor's recommendations. Capsules and tablets are easy to swallow and may be the best choice for people who have difficulty swallowing pills. Powders are a good option for people who prefer to mix their supplements with water or juice.

  4. Timing: ALA supplements should be taken at a specific time of day to maximize their effectiveness. Some studies have suggested that taking ALA with meals may improve its absorption, while others have found that taking it on an empty stomach may be more effective. It's important to talk to your doctor about the best time to take your ALA supplement.

Potential Side Effects

ALA supplements are generally safe and well-tolerated. However, like any dietary supplement, they can cause side effects in some people. The most common side effects of ALA supplements include nausea, stomach upset, and skin rash. Less commonly, ALA supplements can cause allergic reactions, including hives and difficulty breathing. If you experience any side effects after taking an ALA supplement, stop taking the supplement and talk to your doctor.

Conclusion

ALA supplements can be a useful addition to your health regimen, but it's important to choose the right product and follow the dosage instructions carefully. Talk to your doctor before taking an ALA supplement, and be sure to report any side effects that you experience. By taking the time to carefully select an ALA supplement and use it as directed, you can help to ensure that you get the maximum benefit from this powerful antioxidant.

Frequently Asked Questions (FAQs)

1. What is alpha-lipoic acid supplement good for?

Alpha-lipoic acid supplements are used to manage and treat chronic diseases associated with oxidative stress, such as diabetic neuropathy. They can also help slow down the onset of metabolic syndrome by acting as an antioxidant.

2. What should you not take alpha-lipoic acid with?

It is important to avoid using alpha-lipoic acid supplements together with other herbal or health supplements that can lower blood sugar. Some examples of these supplements include devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, and Siberian ginseng.

3. Is it safe to take alpha-lipoic acid supplements?

In general, alpha-lipoic acid supplements are safe to take. However, it is important to note that there may be exceptions. For example, high doses of beta carotene have been linked to a higher risk of lung cancer in smokers, and extra calcium and vitamin D may increase the risk of kidney stones. It is always recommended to consult with a healthcare professional before starting any new supplement.

4. What happens when you take alpha-lipoic acid?

Studies have suggested that alpha-lipoic acid supplements may enhance the body's ability to use its own insulin to lower blood sugar in people with type 2 diabetes. It may also help reduce the symptoms of peripheral neuropathy, which is nerve damage that can be caused by diabetes.

5. When should I take alpha-lipoic acid morning or night?

The best time to take alpha-lipoic acid supplements is typically in the morning, at least 30 minutes before eating or drinking anything.

6. Is alpha-lipoic acid hard on kidneys?

Alpha-lipoic acid given as a dietary supplement has actually been shown to have a protective and preventative effect on kidney aging. It has been found to reverse age-related decline in kidney function and serum total proteins. However, it is important to consult with a healthcare professional before starting any new supplement, especially if you have existing kidney issues.

7. Is alpha-lipoic acid hard on the liver?

Alpha-lipoic acid, whether consumed in foods or taken as a supplement, seems to work like an antioxidant. It may provide protection to the brain and be helpful in certain liver diseases. However, as with any supplement, it is important to consult with a healthcare professional before starting alpha-lipoic acid supplements, especially if you have liver conditions.

Editor's Notes

During our alpha lipoic acid supplement research, we found 24 alpha lipoic acid supplement products and shortlisted 10 quality products. We collected and analyzed 223,293 customer reviews through our big data system to write the alpha lipoic acid supplements list. We found that most customers choose alpha lipoic acid supplements with an average price of $19.48.

The alpha lipoic acid supplements are available for purchase. We have researched hundreds of brands and picked the top brands of alpha lipoic acid supplements, including Nutricost, NOW Foods, NUTRAHARMONY, THORNE, Sundown. The seller of top 1 product has received honest feedback from 30,777 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

Alpha Lipoic Acid Supplements Comparison Table

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#TOP10
Brand Nutricost NOW Foods NUTRAHARMONY Horbäach THORNE Sundown Carlyle Superior Labs Pure Encapsulations Vitamatic
Unit Count 240 Count 120 Count 120 Count 240 Count 60.0 Count 60 Count - 120.00 Count 60.0 Count 240 Count
Item Form Capsule Capsule Capsule Capsule Capsule Capsule - Capsule Capsule Capsule
Product Benefits Inflammation Management Heart Health Support, Metabolism Management Antioxidant, Nerve Support Antioxidant Cognition & Focus Antioxidant - Anti-Aging Heart Health Support Circulation Support, Heart Health Support, Metabolism Management, Brain Health Support
Flavor Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored - - Unflavored Unflavored
Item Weight 6 Ounces 0.12 Kilograms - 6.72 Ounces 1.4 Ounces 0.1 Pounds - 0.25 Pounds 0.15 Pounds 0.35 Pounds
Age Range (Description) Adult - Adult Adult Adult Adult - Adult Adult Adult
Item dimensions L x W x H 2.5 x 2.5 x 5 inches 2.5 x 2.5 x 4.44 inches - 2.87 x 2.87 x 5.25 inches 2.09 x 2.09 x 3.72 inches 2.07 x 2.07 x 3.77 inches - 2.5 x 2.5 x 4.3 inches 3.9 x 2.3 x 1.9 inches -
Special Ingredients Lipoic Acid Lipoic Acid - Alpha Lipoic Acid, Biotin - - - Alpha Lipoic Acid - Alpha Lipoic Acid
Diet Type Vegan Vegan - Gluten Free - Gluten Free - Gluten Free - -
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.3
ftb score rating icon 9.2
ftb score rating icon 9.0
ftb score rating icon 9.0
ftb score rating icon 8.8
ftb score rating icon 8.8
ftb score rating icon 8.6
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