Best DMAE Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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DMAE supplements are a popular nootropic supplement that has been known to improve cognitive function and memory. DMAE, or Dimethylaminoethanol, is a compound that is naturally found in the brain and is believed to help increase the production of acetylcholine, a neurotransmitter that is essential for cognitive function. DMAE supplements are available in capsule or powder form and are often used by students, professionals, and seniors to help improve focus, concentration, and memory retention. It is important to note that while DMAE supplements have been shown to be effective in some studies, more research is needed to fully understand its benefits and potential side effects.

At a Glance: Our Top Picks

NOW Supplements DMAE 250mg Cover #TOP 1
NOW Supplements DMAE 250mg
ftb score rating icon 9.9
Source Naturals DMAE, Dimethylaminoethanol Bitartrate - 200 Capsules Cover #TOP 2
Source Naturals DMAE, Dimethylaminoethanol Bitartrate - 200 Capsules
ftb score rating icon 9.8
Life Extension DMAE Bitartrate - Brain Health, Focus and Memory Supplement Cover #TOP 3
Life Extension DMAE Bitartrate - Brain Health, Focus and Memory Supplement
ftb score rating icon 9.6

Top 10 DMAE Supplements

#TOP 1

NOW Supplements DMAE 250mg

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NOW Supplements DMAE 250mg Cover
NOW Foods Supplements, DMAE (Dimethylaminoethanol) 250 mg, Healthy Brain Function*, 100 Veg Capsules

NOW Supplements DMAE (Dimethylaminoethanol) 250 mg is a dietary supplement that supports healthy brain function*. It contains Amino Acid and is suitable for adults. It is packaged in the USA by a family owned and operated company since 1968 and is GMP Quality Assured. Customers report feeling more alert, sharper, and better able to concentrate after taking this supplement.

What We Like
Supports Neurotransmitter Production*
GMP Quality Assured
Packaged in the USA by a family owned and operated company since 1968
#TOP 2

Source Naturals DMAE, Dimethylaminoethanol Bitartrate - 200 Capsules

021078015833
Source Naturals DMAE, Dimethylaminoethanol Bitartrate - 200 Capsules Cover
Source Naturals DMAE, Dimethylaminoethanol Bitartrate - Supports Mental Concentration - 200 Capsules

Source Naturals DMAE is a well-made supplement that supports mental concentration. With its ability to easily cross the blood-brain barrier, DMAE plays a crucial role in the formation of acetylcholine, an important neurotransmitter responsible for memory and muscle movement. By taking 1 to 2 capsules daily, you can provide the support that your neurotransmitters need to perform their vital functions in the brain. This supplement is manufactured in the USA and is free from yeast, gluten, corn, sugar, starch, salt, preservatives, artificial color, flavor, or fragrance. Trust Source Naturals, a brand that has been trusted for over 35 years, to help you reach your optimal health potential.

What We Like
Supports mental concentration
Well-made supplement
No artificial additives
#TOP 3

Life Extension DMAE Bitartrate - Brain Health, Focus and Memory Supplement

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Life Extension DMAE Bitartrate - Brain Health, Focus and Memory Supplement Cover
Life Extension DMAE Bitartrate, Supports neurotransmitter Production, 6-Month Supply, Gluten-Free, Non-GMO, Vegetarian, 200 Capsules

Life Extension DMAE Bitartrate is a brain health supplement designed to support essential neurotransmitter choline production. It contains 150 mg of DMAE to help protect cell membranes and support free radical scavenging activity. This product is certified non-GMO and gluten-free, and is suitable for vegetarians. Customers report improved memory recall, increased clarity of mind, and better concentration with no side effects.

What We Like
Supports essential neurotransmitter choline production
Protects cell membranes
Certified non-GMO and gluten-free
Suitable for vegetarians
Customers report improved memory recall, clarity of mind, and better concentration
#TOP 4

Source Naturals DMAE Tablets

Source Naturals DMAE Tablets Cover
Source Naturals DMAE, Dimethylaminoethanol Bitartrate - Supports Mental Concentration - 200 Tablets

Source Naturals DMAE, Dimethylaminoethanol Bitartrate, is a well-made supplement that supports mental concentration. It contains no yeast, gluten, corn, sugar, starch, salt, preservatives, or artificial color, flavor or fragrance. It is a hypoallergenic vegetarian product, and is manufactured in the USA under the Good Manufacturing Practices (cGMPs). Customers report that it helps with mental clarity, fatigue, and brain fog, and can be taken as one tablet 1 to 2 times daily.

What We Like
Contains no artificial ingredients
Manufactured in the USA
Helps with mental clarity, fatigue, and brain fog
Easy to take
#TOP 5

Pure DMAE Bitartrate Capsules (365 ct.) - No Fillers

Pure DMAE Bitartrate Capsules (365 ct.) - No Fillers Cover
Pure Original Ingredients DMAE Bitartrate (365 Capsules) No Magnesium Or Rice Fillers, Always Pure, Lab Verified

These DMAE Bitartrate Capsules are pure, undiluted supplements that contain only one ingredient - DMAE Bitartrate. It is naturally found in anchovies and sardines. The capsules are free from additives, stearates, and rice fillers, making them always pure. Each bottle contains 365 capsules, enough for a year of peak health support. The product is packaged in Utah, USA.

What We Like
Pure DMAE Bitartrate supplement with no additives or fillers
Naturally sourced from anchovies and sardines
Large 365-day supply for year-round health support
#TOP 6

Horbaach DMAE Supplement

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Horbaach DMAE Supplement Cover
Horbaach DMAE Supplement | 250mg | 200 Capsules | Non-GMO, Gluten Free | DMAE Bitartrate

Horbaach's DMAE Supplement is a quick-release capsule containing 250mg of DMAE Bitartrate. It is Non-GMO, Gluten Free, and scientifically designed to provide optimal support. Customers have reported improved memory, strategic thinking, and skin care benefits. However, some have experienced headaches when taking the supplement.

What We Like
Non-GMO and Gluten Free
Scientifically designed for optimal support
Customers have reported improved memory, strategic thinking, and skin care benefits
#TOP 7

BulkSupplements DMAE Bitartrate Capsules

BulkSupplements DMAE Bitartrate Capsules Cover
BulkSupplements.com DMAE Bitartrate Capsules - Dimethylaminoethanol, DMAE 350mg, DMAE Supplement, DMAE Capsules - for Brain Health & Focus, Gluten Free, 1 Capsule per Serving, 365 Capsules

BulkSupplements DMAE Capsules are designed to support your brain health and enhance your focus. By incorporating these capsules into your daily routine, you may experience improved concentration for work, school, or any activities. These capsules also promote an overall sense of well-being, helping you feel your best throughout the day. With their convenient formulation, taking one capsule is all it takes to boost your diet. Plus, they are gluten-free, dairy-free, soy-free, and sugar-free, making them a guilt-free addition to your supplement regimen. Enjoy the benefits of high-quality DMAE in a hassle-free way!

What We Like
Supports brain health
Enhances focus and concentration
Promotes overall well-being
Convenient one-capsule serving
Gluten-free and allergen-free
#TOP 8

Nutricost DMAE-Bitartrate Powder

No Model Number
Nutricost DMAE-Bitartrate Powder Cover
Nutricost Pure DMAE-Bitartrate Powder 100 Grams

Nutricost's DMAE-Bitartrate Powder is a high-quality supplement that contains 350mg of DMAE-Bitartrate per serving. It is gluten-free, non-GMO, and manufactured in a GMP compliant, FDA registered facility. Customers have reported that it helps to lift, plump, and brighten their skin, and that it helps with brain fog. The product comes in a 100 gram tub with 286 servings.

What We Like
Gluten-free and non-GMO
Manufactured in a GMP compliant, FDA registered facility
Helps to lift, plump, and brighten skin
Helps with brain fog
#TOP 9

BlueBonnet DMAE Supplement

BLB01090
BlueBonnet DMAE Supplement Cover
BlueBonnet DMAE Supplement, 100 Count

BlueBonnet DMAE Supplement is a 100 count capsule of 100 mg of 2-dimethylaminoethanol bitartrate (DMAE). It supports healthy brain function and neurotransmitter production, and is free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. It is also gluten-free, soy-free, non-GMO, kosher certified, and vegan. Customers have reported that it works well and is an economical product.

What We Like
Vegetarian-friendly
Supports healthy brain function
Non-GMO, gluten-free, and vegan
Economical
Highly rated by customers
#TOP 10

Force Factor DMAE Brain Supplement

FFS-01282-FG
Dmae
Force Factor DMAE Brain Supplement Cover
FORCE FACTOR DMAE Supplement for Concentration, Focus, and Healthy Cognitive Function, Brain Supplement & Neurotransmitter Support, Vegan, Non-GMO, 100 Capsules

Force Factor DMAE is designed to enhance your cognitive abilities and improve focus. This supplement supports overall brain health, helping you think clearly and perform at your best. You can expect better concentration, allowing you to stay on task and achieve your goals more efficiently. Additionally, it aids in maintaining neurotransmitter balance, which is essential for optimal brain communication and clarity. With its premium quality and vegan-friendly formula, you can feel confident in your choice for a natural brain boost.

What We Like
Cognitive enhancement
Improved focus
Neurotransmitter support
Vegan-friendly ingredients
Made in the USA
Buying Guide Image

Everything You Need to Know About DMAE Supplements

What is DMAE?

DMAE is an abbreviation for dimethylaminoethanol, which is a compound found naturally in the human brain. It is a precursor to the neurotransmitter acetylcholine, which is important for memory and learning. DMAE has been studied for its potential to improve mental focus, and is thought to help reduce inflammation, support immune system health, and possibly even improve skin tone.

Benefits of DMAE Supplements

The potential benefits of taking DMAE supplements include improved mental focus, concentration, and memory; increased energy levels; improved immune system health; and reduced inflammation. Additionally, some studies suggest that DMAE may improve skin tone, although further research is needed to confirm this.

What to Look for in DMAE Supplements

When selecting a DMAE supplement, it is important to look for one that is of high quality and contains the right ingredients. Quality DMAE supplements should be made from natural sources, such as sardines, anchovies, and other cold-water fish, as these are the best sources of DMAE. The supplement should also be free of any artificial ingredients, fillers, preservatives, or additives. Additionally, it is important to make sure the supplement is third-party tested for purity and potency.

Dosage and Side Effects

The recommended dosage of DMAE supplements varies depending on the individual’s age and health status. It is important to speak to a healthcare professional before starting any supplement regimen. Common side effects of DMAE supplements include headache, upset stomach, and insomnia. If any of these side effects occur, it is important to stop taking the supplement and consult a healthcare professional.

Conclusion

DMAE supplements may offer potential benefits such as improved mental focus, increased energy levels, and improved immune system health. When selecting a DMAE supplement, it is important to look for one that is of high quality and contains the right ingredients. Additionally, it is important to speak to a healthcare professional before starting any supplement regimen and to be aware of potential side effects. With the right supplement and dosage, DMAE may offer a range of potential health benefits.

Frequently Asked Questions (FAQs)

1. What is DMAE supplement used for?

DMAE supplements are used for various cognitive and disruptive disorders, including ADHD and memory lapses. It is also used in skincare products to address sagging skin and age spots.

2. Are DMAE supplements safe?

The safety of DMAE supplements is not well-established. Some studies have reported side effects like stomach upset and drowsiness in a percentage of patients taking DMAE for tardive dyskinesia. It is recommended to exercise caution when using DMAE supplements.

3. Does DMAE have side effects?

Clinical studies have used up to 1,600 mg of DMAE per day with no reported side effects. However, higher intakes for Alzheimer's disease patients have shown symptoms of drowsiness and confusion. Overall, DMAE is considered relatively nontoxic, but individual responses may vary.

4. Is DMAE a stimulant?

DMAE is classified as a mild central nervous system stimulant. It can improve moods and reduce sluggishness. This stimulant effect is attributed to DMAE's ability to stabilize cell membranes, benefiting both the skin and brain functions.

5. Is DMAE anti-inflammatory?

In vitro studies suggest that DMAE has moderate anti-inflammatory properties. While its mechanisms of action in the skin are not fully understood, evidence indicates that the skin is actively involved in acetylcholine synthesis, storage, secretion, metabolism, and receptivity.

6. Can you take DMAE daily?

Clinical studies have used doses of up to 1,600 mg of DMAE per day without reporting side effects or known drug interactions. Regular supplementation with DMAE is generally well-tolerated, but it is advisable to be aware of potential side effects and consider individual circumstances.

7. How long does it take for DMAE to start working?

It typically takes about three weeks of continuous DMAE intake before initial results become noticeable. For optimal results, it is recommended to take DMAE daily for three months.

8. When is the best time to take DMAE?

DMAE is best taken in the morning, preferably with breakfast. It is advised to dose DMAE a few times a week rather than daily. If using DMAE, consider stacking it with a good source of choline, as DMAE can inhibit choline metabolism.

9. What foods are high in dimethylaminoethanol?

Fish and seafood, such as salmon, oysters, rainbow trout, mackerel, tuna, halibut, sardines, and anchovies, contain high amounts of dimethylaminoethanol (DMAE). These foods are natural sources of DMAE.

10. Does DMAE cause cell death?

In vitro studies have shown that DMAE can cause damage to cells and lead to vacuolization. This vacuolization can inhibit cell division and secretion, potentially resulting in cell death after a certain period of time.

Editor's Notes

During our dmae supplement research, we found 24 dmae supplement products and shortlisted 10 quality products. We collected and analyzed 19,389 customer reviews through our big data system to write the dmae supplements list. We found that most customers choose dmae supplements with an average price of $17.28.

The dmae supplements are available for purchase. We have researched hundreds of brands and picked the top brands of dmae supplements, including NOW Foods, Source Naturals, Life Extension, PURE ORIGINAL INGREDIENTS, BulkSupplements. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.