Best CoQ10 Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 11, 2026

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CoQ10 is a popular supplement that is known for its energy-boosting and antioxidant properties. It is naturally produced by the body, but levels may decrease with age or certain health conditions. CoQ10 supplements come in various forms, including capsules, softgels, and chewables, and are often used to support heart health, improve exercise performance, and enhance overall energy levels. Some studies have also shown potential benefits for conditions such as migraines, Parkinson's disease, and high blood pressure. However, it is important to consult with a healthcare provider before starting any new supplement regimen.

At a Glance: Our Top Picks

Qunol Ultra CoQ10 Softgels Cover #TOP 1
Qunol Ultra CoQ10 Softgels
ftb score rating icon 9.8
Puritan's Pride CoQ10 Supplement for Heart Health, 240 Softgels Cover #TOP 2
Puritan's Pride CoQ10 Supplement for Heart Health, 240 Softgels
ftb score rating icon 9.7
Qunol CoQ10 Softgels - Better Absorption & Energy Production Cover #TOP 3
Qunol CoQ10 Softgels - Better Absorption & Energy Production
ftb score rating icon 9.5

Top 10 CoQ10 Supplements

#TOP 1

Qunol Ultra CoQ10 Softgels

QULT120
Qunol Ultra CoQ10 Softgels Cover
Qunol CoQ10 100mg Softgels, Ultra CoQ10 100mg, 3x Better Absorption, Antioxidant for Heart Health & Energy Production, Coenzyme Q10 Vitamins and Supplements, 4 Month Supply, 120 Count

Qunol Ultra CoQ10 Softgels are a top-rated CoQ10 supplement that offers 3x better absorption than regular CoQ10. This supplement is 100% water and fat-soluble, making it easier for the body to absorb and utilize. With 100mg of CoQ10 per softgel, Qunol Ultra can help support heart health, energy production, and overall vitality. It's no wonder why this is the #1 cardiologist recommended form of CoQ10 on the market.

What We Like
Easy to swallow
No taste or aftertaste
Improved energy levels
Better absorption
Supports heart and cholesterol health
What We Don't Like
Large pill size for some
Capsule clumping (rare)
#TOP 2

Puritan's Pride CoQ10 Supplement for Heart Health, 240 Softgels

50095
Brown
Puritan's Pride CoQ10 Supplement for Heart Health, 240 Softgels Cover
Puritan's Pride CoQ10 200mg, Supports Heart Health, 240 Rapid Release Softgels

Puritan's Pride CoQ10 200mg Supplement is designed to support a healthy heart and cardiovascular system. The product promotes energy production within your heart and muscles, and supports good oral health to keep your cardiovascular health in check. The softgels are easy to swallow and have superior absorption. However, customers should be available during the product delivery to prevent melting/damage from exposure to heat or sunlight. During summer, Amazon stores and ships products in accordance with the manufacturer's recommendations.

What We Like
Good value for quantity
Trusted brand reputation
Easy-to-swallow capsules
Secure packaging
Consistent quality
What We Don't Like
Some brands have fewer additives
#TOP 3

Qunol CoQ10 Softgels - Better Absorption & Energy Production

TT440
No Color
Qunol CoQ10 Softgels - Better Absorption & Energy Production Cover
Qunol Ultra CoQ10 100mg Softgels- 3x Better Absorption, Antioxidant for Heart Health & Energy Production, Coenzyme Q10 Vitamins and Supplements, 3 Month Supply, 90 Count

Qunol CoQ10 Softgels Ultra 3X Better Absorption Coenzyme Q10 Supplement is clinically proven to absorb 3 times better than regular CoQ10 supplements. It helps increase natural CoQ10 levels in the body for energy production, which can be depleted by age and cholesterol-lowering statin medications. The patented formulation is 100% water and fat-soluble while being beneficial to statin drug users. Additionally, Qunol offers a satisfaction guarantee.

What We Like
Superior absorption rate
Supports heart health
Boosts energy levels
Easy to swallow softgels
Good value for quantity
What We Don't Like
Softgels slightly large
Mild aftertaste for some
#TOP 4

Nature Made CoQ10 200 mg Softgels

3111
105 Count
Nature Made CoQ10 200 mg Softgels Cover
Nature Made CoQ10 200mg, Dietary Supplement for Heart Health Support, 105 Softgels, 105 Day Supply

Nature Made CoQ10 200 mg Softgels are a dietary supplement for heart health support. This 105-day supply of 200 mg CoQ10 supplements provide antioxidant support to help fight free radicals in the body and to protect cells from oxidative damage. They are gluten free, have no color added, no artificial flavors and no preservatives. Customers have reported positive results, such as relief from nighttime leg cramps, and have praised the product for its effectiveness and fast delivery.

What We Like
Heart health support
Trusted brand reputation
Antioxidant benefits
Easy-to-swallow softgels
Dental health improvement
What We Don't Like
Occasional damaged packaging
Uncertain measurable effects
#TOP 5

Qunol CoQ10 200mg Softgels

ZFW-1149
Qunol CoQ10 200mg Softgels Cover
Qunol CoQ10 200mg Softgels, Ultra CoQ10 - Ultra High Absorption Coenzyme Q10 Supplements - Antioxidant Supplement for Vascular and Heart Health & Energy Production - 2 Month Supply - 60 Count

Qunol CoQ10 200mg Softgels is an ultra high absorption Coenzyme Q10 supplement that is beneficial to statin drug users and essential for energy production. Its patented formulation is 100% water and fat-soluble, making it more absorbable than regular CoQ10. It is the #1 cardiologist recommended form of CoQ10 and comes in a 60 count bottle. Customers have noted that the pills are large and may be difficult to swallow.

What We Like
Affordable price
High quality
Beneficial for statin users
Easy to swallow
What We Don't Like
Large capsule size
Minimal savings with subscription
#TOP 6

Doctor's Best High Absorption CoQ10

DRB-00183
No Color
Doctor's Best High Absorption CoQ10 Cover
Doctor's Best High Absorption CoQ10 with BioPerine, Gluten Free, Naturally Fermented, Heart Health, Energy Production, 100 mg, 120 Count

Doctor's Best High Absorption CoQ10 with BioPerine is an easy-to-absorb form of a key nutrient that powers and protects heart vitality, cardiovascular health and cellular energy. It is formulated with BioPerine, a natural black pepper extract, to help restore your body's depleted CoQ10 stores quickly and efficiently. It is also gluten-free and made of either bacterial or yeast fermentation. Statin drug users may find this product especially beneficial.

What We Like
Easy-to-swallow softgels
Supports energy and heart health
High absorption with BioPerine
No aftertaste or stomach upset
Excellent value and trusted brand
What We Don't Like
Gel tablets may stick together
Benefits take time to appear
#TOP 7

Qunol Ubiquinol CoQ10 200mg Softgels

898440001790
Qunol Ubiquinol CoQ10 200mg Softgels Cover
Qunol 200mg Ubiquinol, Powerful Antioxidant for Heart and Vascular Health, Essential for energy production, Natural Supplement Active Form of CoQ10, 60 Count

Qunol Ubiquinol CoQ10 200mg Softgels is a gluten-free natural supplement that provides a powerful antioxidant effect, essential to support heart and vascular health, and energy production. This supplement contains ubiquinol, the active and antioxidant form of CoQ10, which neutralizes excess free radicals and helps protect cells against damage. Ubiquinol plays a crucial role in producing the energy needed by our organs, and its levels may decrease due to age, stress, and medications. Customers should be available during delivery to avoid melting/damage of the product caused by heat or sunlight exposure.

What We Like
High absorption Ubiquinol form
Extra strength 200mg dosage
Supports heart and energy health
Trusted, clinically supported brand
Easy-to-swallow softgels
What We Don't Like
Shorter 2-month supply per bottle
Slightly higher price
#TOP 8

JulyDeer CoQ10 200mg with Vitamin E

BG021
60 Count(Pack of 1)
JulyDeer CoQ10 200mg with Vitamin E Cover
JulyDeer CoQ10 200mg with Vitamin E 20mg, High Absorption Antioxidant Coenzyme Q10 Support for Heart, Energy, Overall Health Supplement 60 Capsules

The JulyDeer CoQ10 Supplement offers a powerful boost to your heart health and energy levels with 200mg of Coenzyme Q10 and 20mg of Vitamin E in each easy-to-digest capsule. Designed for daily use, a bottle provides a convenient 60-day supply, so you won’t have to worry about frequent refills. This supplement supports your body's natural energy production at the cellular level, helping you feel more energized and promoting healthy aging. Together, CoQ10 and Vitamin E work to protect your body from oxidative stress, supporting overall vitality and heart function.

What We Like
Easy to swallow capsules
No odor or taste
Accurate capsule count
Long expiration date
Mid to upper dosage range
What We Don't Like
Requires caution with some medications
#TOP 9

Nutricost CoQ10 100mg Vegetarian Capsules

KQ-KVNU-AY1P
White
Nutricost CoQ10 100mg Vegetarian Capsules Cover
Nutricost CoQ10 100mg, 120 Vegetarian Capsules, 120 Servings - High Absorption, Vegetarian, Non-GMO, Coenzyme Q10

The Nutricost CoQ10 100mg Vegetarian Capsules offer premium grade Coenzyme Q10 with 120 vegetarian capsules per bottle, providing high absorption and just one capsule per serving. The product is non-GMO, gluten-free, and made in a GMP-compliant, FDA-registered facility that undergoes third-party testing for quality assurance.

What We Like
Easy to swallow capsules
Vegetarian and non-GMO
Good value for money
Supports energy and heart health
May help with joint pain
What We Don't Like
Energy boost less than some liquid capsules
#TOP 10

Qunol CoQ10 Gummies for Heart Health Support

FETEGT1283
Orange
Qunol CoQ10 Gummies for Heart Health Support Cover
Qunol CoQ10 Gummies, CoQ10 100mg, Delicious Gummy Supplements, Helps Support Heart Health, Vegan, Gluten Free, Ultra High Absorption, 2 Month Supply (60 Count, Pack of 2)

Qunol CoQ10 Gummies are a tasty alternative to pills, providing 100mg of CoQ10 per serving. With a delicious creamy orange flavor, these gluten-free gummies are easy to take and help support healthy heart function. CoQ10 acts as an antioxidant and helps protect cells from damage caused by free radicals. Additionally, CoQ10 plays a vital role in energy production, making it essential for those who may be experiencing age or stress-related depletion. The patented water dispersion technology used in Qunol CoQ10 Gummies ensures ultra-high absorption.

What We Like
Tasty fruity flavor
Convenient gummy form
Increased energy and focus
Vegan and gluten-free
Natural ingredients
What We Don't Like
Contains some sugar
Can get sticky
Buying Guide Image

Some Factors You Should Know About CoQ10 Supplements

What is CoQ10?

CoQ10, also known as ubiquinone, is a substance found naturally in the body. It is a key component of the cells' mitochondria, where it helps generate energy for the body. CoQ10 levels are highest in organs that require a lot of energy, such as the heart, liver, and kidneys.

What are CoQ10 supplements used for?

CoQ10 supplements are commonly used to treat or prevent a variety of conditions, including heart disease, high blood pressure, and cancer. They are also sometimes used to improve physical performance and reduce the effects of aging.

How to choose the right CoQ10 supplement

When choosing a CoQ10 supplement, it's important to consider several factors. Here are some things to keep in mind:

  1. Form: CoQ10 supplements come in several different forms, including capsules, tablets, and liquid. Capsules and tablets are the most common, but some people may find liquid supplements easier to swallow.

  2. Dosage: The recommended daily dose of CoQ10 varies depending on the condition being treated. In general, most adults can take up to 200-300 mg per day, but it's important to check with your doctor to determine the right dose for you.

  3. Quality: As with any supplement, it's important to choose a high-quality product. Look for a supplement that has been certified by a third-party organization, such as the U.S. Pharmacopeia (USP) or ConsumerLab. These organizations test supplements for purity and potency.

  4. Price: CoQ10 supplements can vary greatly in price. Don't be swayed by the lowest price, but don't automatically choose the most expensive option either. Instead, look for a product that offers a good value for the price.

Conclusion

CoQ10 supplements can be an effective way to support your health and well-being. By considering factors such as form, dosage, quality, and price, you can find the right CoQ10 supplement for your needs. Always check with your doctor before taking any supplement, and follow the instructions on the label carefully.

Frequently Asked Questions (FAQs)

1. What is CoQ10 supplement good for?

CoQ10 supplements have been found to potentially improve heart health, blood sugar control, and help manage high blood pressure in individuals with diabetes. However, the effects of CoQ10 on blood sugar control may vary among individuals. It is important to consult with a healthcare professional before starting CoQ10 supplements, especially if you have diabetes.

2. Is there any downside to taking CoQ10?

Most people tolerate CoQ10 well, but some may experience mild side effects such as stomach upset, loss of appetite, nausea, vomiting, diarrhea, and allergic skin rashes. CoQ10 may also lower blood pressure, so individuals with very low blood pressure should monitor their blood pressure carefully. If you experience any adverse reactions, it is recommended to discontinue use and consult a healthcare professional.

3. Is it safe to take CoQ10 everyday?

CoQ10 is generally considered safe for daily use. The recommended daily dosage typically ranges from 90-200 mg, but higher dosages of 300-600 mg may be necessary for specific conditions. CoQ10 is a well-tolerated supplement that can be beneficial for those looking to support their overall health naturally. However, it is always advisable to consult with a healthcare professional before starting any new supplement regimen.

4. Who needs to take CoQ10?

CoQ10 may be beneficial for individuals with congestive heart failure, cardiomyopathy, neurologic disorders like Parkinson's disease or Huntington's disease, dysfunctional mitochondria, high blood pressure, migraine headaches, or those who have recently had a heart attack. It is important to consult with a healthcare professional to determine if CoQ10 is appropriate for your specific health needs.

5. What are the symptoms of needing CoQ10?

The symptoms of needing CoQ10 may include neurological abnormalities like seizures, intellectual disability, poor muscle tone, involuntary muscle contractions, progressive muscle stiffness, abnormal eye movements, and degenerative vision loss. However, it is essential to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.

6. What are the side effects of taking CoQ10?

CoQ10 generally does not cause serious side effects. Mild side effects like insomnia or digestive upsets may occur. CoQ10 may interact with certain medications such as the anticoagulant warfarin and the diabetes drug insulin. It is also important to note that CoQ10 may not be compatible with certain types of cancer treatment. Consult with a healthcare professional before taking CoQ10, especially if you are taking other medications or undergoing cancer treatment.

7. Should I take CoQ10 in the morning or at night?

CoQ10 is a fat-soluble supplement and should ideally be taken with a meal that contains fats or oils. It can be taken in the morning or at night, as long as it is accompanied by food. Taking CoQ10 with a meal enhances its absorption and utilization by the body.

Editor's Notes

During our coq10 supplement research, we found 25 coq10 supplement products and shortlisted 10 quality products. We collected and analyzed 683,216 customer reviews through our big data system to write the coq10 supplements list. We found that most customers choose coq10 supplements with an average price of $23.76.

The coq10 supplements are available for purchase. We have researched hundreds of brands and picked the top brands of coq10 supplements, including Qunol, Puritan's Pride, Nature Made, Doctor's BEST, JulyDeer. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

CoQ10 Supplements Comparison Table

#TOP1
#TOP2
#TOP3
#TOP4
#TOP5
#TOP6
#TOP7
#TOP8
#TOP9
#TOP10
Brand Qunol Puritan's Pride Qunol Nature Made Qunol Doctor's BEST Qunol JulyDeer Nutricost Qunol
Flavor Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored Orange
Primary Supplement Type CoQ10 multivitamin CoQ10 Vitamin CoQ10 CoQ10 CoQ10 CoQ10 200mg with Vitamin E 20mg CoQ10 CoQ10
Unit Count 120 Count 240 Count 90 Count 105 Count 60 Count 120 Count 60 Count 60.0 Count 120 Count 120 Count
Item Form Softgel Softgel Softgel Softgel Softgel Softgel Softgel Capsule Capsule Gummy
Product Benefits Energy Management, Heart Health Support, Vascular Health Support, Antioxidant, Beneficial to Statin Users Health,Heart Health,Supports Beneficial to Statin Users, Blood Pressure Management, Heart Health Support, Vascular Health Support Heart Health Support Antioxidant, Beneficial to Statin Users, Energy Management, Heart Health Support, Vascular Health Support Energy Management Energy Management, Heart Health Support Support for Heart, Energy Energy Management Hearth Health Support,Energy Management
Item Weight 7.7 Ounces 0.53 Pounds 0.37 Pounds 3.84 Ounces 0.31 Pounds 0.1 Pounds 0.25 Pounds - 0.01 Ounces 1.05 Pounds
Special Ingredients Coenzyme Q Coenzyme Q Coenzyme Q Coenzyme Q Coenzyme Q Coenzyme Q Coenzyme Q - Coenzyme Q Coenzyme Q
Diet Type Gluten Free Gluten Free Gluten Free Gluten Free Gluten Free Gluten Free Gluten Free - Gluten Free Gluten Free
Item dimensions L x W x H 2.75 x 5.25 x 5.25 inches 2.66 x 2.66 x 4.74 inches 4.8 x 2.5 x 2.45 inches 2.44 x 2.44 x 4.38 inches - 2.13 x 2.13 x 3.69 inches 2.5 x 2.5 x 4.75 inches - 2.25 x 4 x 2.25 inches 5.36 x 5.36 x 4.92 inches
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.3
ftb score rating icon 9.2
ftb score rating icon 9.0
ftb score rating icon 9.0
ftb score rating icon 8.8
ftb score rating icon 8.7
ftb score rating icon 8.6
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