Best Suppository Laxatives of 2025

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Suppository laxatives are a type of medication that can be inserted directly into the rectum to help relieve constipation. They come in a variety of forms, including glycerin, bisacodyl, and docusate sodium. These products work by stimulating the muscles in the rectum to help move stool out of the body. Suppository laxatives are often used when oral laxatives are ineffective or not recommended, such as in cases of nausea or vomiting. They are generally safe to use, but it is important to follow the instructions carefully and speak with a healthcare provider if you have any concerns.
At a Glance: Our Top Picks
Top 10 Suppository Laxatives
Dulcolax Bisacodyl Suppositories
Dulcolax Laxative Suppositories provide quick relief from constipation, acting within 15 to 60 minutes. These suppositories work effectively by delivering the active ingredient, bisacodyl, directly to the source of discomfort in the rectum, promoting gut movement. This targeted approach ensures you get the relief you need right where it counts. Plus, their compact size makes them perfect for travel, so you can maintain regularity even when life gets hectic. Recommended by doctors, these comfort-shaped suppositories are designed for easy insertion and retention, helping you feel better fast.
Fleet Laxative Suppositories with Aloe vera, 50 Count
Get fast, reliable relief from occasional constipation with Fleet Laxative Glycerin Suppositories. The comfort-shaped suppositories include aloe vera to make insertion easier, while glycerin works by attracting water into the stool to promote a bowel movement. This stimulant-free formula ensures predictable relief within 15 minutes to an hour. Fleet is a trusted brand with a long history of producing effective suppositories. Each jar includes 50 suppositories.
AVEDANA Laxative Suppositories - Fast and Gentle Relief
The AVEDANA Laxative Suppositories offer a fast and gentle solution to occasional constipation. The bisacodyl suppositories contain a powerful formula that stimulates bowel movement in a natural way, providing relief as quickly as 15 minutes to an hour. The comfort-shaped suppositories make insertion easy and pain-free, while the compact pack of 16 pieces is convenient and affordable to carry.
Avedana Glycerin Suppositories for Constipation Relief
The Avedana glycerin suppositories are a fast and gentle solution for occasional constipation. With a special formula and 2g of glycerin per capsule, these suppositories can bring relief within minutes from insertion. The ergonomic shape ensures easy and painless insertion. Glycerin can help stimulate bowel movement, so drinking plenty of water will help achieve maximum benefits.
Fleet Liquid Glycerin Suppositories for Adult Constipation
Fleet Liquid Glycerin Suppositories are an easy-to-use solution for occasional constipation and irregularity. The suppositories provide fast and predictable relief by gently unblocking your system. The glycerin suppository works quickly by attracting water into the colon, promoting a bowel movement within 15 minutes to 1 hour. Fleet Liquid Glycerin Suppositories come with a mess-free applicator and lubricated gentle glide tip to ensure gentle constipation relief. The product is stimulant-free and is doctor-recommended for reliable constipation relief.
Rite Aid Fast Relief Laxative Suppositories, Bisacodyl USP, 10mg - 16 Count
Get fast-acting relief from occasional constipation with Rite Aid Fast Relief Laxative Suppositories. Suitable for adults and children, these suppositories contain Bisacodyl USP, 10mg, a stimulant laxative that often works in 15 minutes to 1 hour. Insertion is easy, and the suppository need not melt completely to produce the desired effect. Each suppository contains 10mg of Bisacodyl, and the trusted brand has been providing effective health and wellness products since 1962.
Rising Health Fast Relief Laxative Suppositories
Rising Health Laxative Suppositories provide quick relief from occasional constipation. With 10 mg of Bisacodyl in each suppository, you can expect effective results in as little as 15 minutes to 1 hour. These suppositories are designed for both adults and children aged 6 and older, making them a versatile option for family use. The easy application process allows you to relieve discomfort quickly and painlessly, without needing the suppository to melt completely. Enjoy the convenience of reliable constipation relief with Rising Health's trusted product.
Fleet - Adult Glycerin Suppositories
Fleet Adult Glycerin Suppositories is a doctor-recommended laxative that provides gentle and effective relief of occasional constipation. The suppositories work within 15 minutes to 1 hour and are now formulated with Aloe for added benefits.
Puregen Labs Bisacodyl Laxative Suppositories
Puregen Labs Laxative Suppositories offer quick relief from occasional constipation. With a powerful 10 mg bisacodyl formula, these suppositories help stimulate your intestines, making it easier for you to pass stool. They’re designed for rectal use only, ensuring you get targeted relief where you need it most. You can expect results in just 15 to 60 minutes, allowing you to say goodbye to uncomfortable feelings of irregularity. Plus, knowing that this product is made in the USA under strict safety guidelines adds an extra layer of reassurance.
Dulcolax Medicated Suppositories 16ct
Dulcolax Suppositories offer quick relief from constipation, acting within 15 to 60 minutes. Designed for rectal use only, these comfort-shaped suppositories are easy to insert and provide effective results. The active ingredient, bisacodyl, works by stimulating bowel movements, helping to ease discomfort. As the number one recommended laxative brand by doctors, you can trust Dulcolax to deliver reliable and fast results when you need them most.
Frequently Asked Questions (FAQs)
1. Is a suppository better than a laxative?
Though using a suppository or enema in the rectum is not as convenient (or pleasant) as swallowing a pill, these manually inserted (or squirted) laxatives often work much faster to relieve symptoms.
2. How long does a suppository laxative take to work?
Take the wrapping off and push a suppository gently into your anus (bottom). Suppositories work quickly (usually between 10 and 45 minutes), so use it when you know you will be near a toilet.
3. How long after laxative suppository Can I poop?
It works by drawing water into the intestines. This effect usually results in a bowel movement within 15 to 60 minutes.
4. Is laxative suppository safe?
These are called osmotic laxatives and include Milk of Magnesia (MOM), glycerin suppositories, enemas, and a prescription called lactulose. They are generally safe for use on a regular basis but, if you have renal or heart problems, you will need to consult with your physician before taking MOM.
During our suppository laxative research, we found 24 suppository laxative products and shortlisted 10 quality products. We collected and analyzed 121,951 customer reviews through our big data system to write the suppository laxatives list. We found that most customers choose suppository laxatives with an average price of $15.51.
The suppository laxatives are available for purchase. We have researched hundreds of brands and picked the top brands of suppository laxatives, including Dulcolax, Fleet, AVEDANA, Rite Aid, Rising. The seller of top 1 product has received honest feedback from 910 consumers with an average rating of 4.2.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.