Best Ibuprofen for Migraine of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 18, 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Ibuprofen is a common over-the-counter medication used to alleviate the symptoms of migraines. This nonsteroidal anti-inflammatory drug (NSAID) works by reducing inflammation and blocking the production of certain chemicals in the body that cause pain and fever. Ibuprofen is available in various forms, including tablets, capsules, and liquid suspensions. It is recommended to take ibuprofen as soon as possible after the onset of a migraine to achieve the best results. However, it is important to follow the dosage instructions carefully and consult a healthcare professional if symptoms persist or worsen.

At a Glance: Our Top Picks

Advil Pain Reliever and Fever Reducer Cover #TOP 1
Advil Pain Reliever and Fever Reducer
ftb score rating icon 9.9
Advil Pain Reliever and Fever Reducer - 100 Coated Tablets Cover #TOP 2
Advil Pain Reliever and Fever Reducer - 100 Coated Tablets
ftb score rating icon 9.8
Timely Ibuprofen 200mg 500 Tablets Cover #TOP 3
Timely Ibuprofen 200mg 500 Tablets
ftb score rating icon 9.6

Top 10 Ibuprofen for Migraine

Advil Pain Reliever and Fever Reducer

305730151122
Advil Pain Reliever and Fever Reducer Cover
Advil Pain Reliever and Fever Reducer, Pain Relief Medicine with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 10 Coated Tablets

Advil Pain Reliever and Fever Reducer is a pain relief medicine that offers 6 hours of relief from headache, backache, menstrual pain, joint pain, minor arthritis pain, muscle aches, and aches and pains from the common cold. The coated tablets are easy to swallow and contain ibuprofen 200mg. The new packaging features 20% less plastic. The product is suitable for adults and children over 12 years old, and is HSA and FSA eligible.

What We Like
Provides 6 hours of relief from various types of pain
Easy to swallow coated tablets
New packaging features 20% less plastic
#TOP 2

Advil Pain Reliever and Fever Reducer - 100 Coated Tablets

305730150408
Advil Pain Reliever and Fever Reducer - 100 Coated Tablets Cover
Advil Pain Reliever and Fever Reducer, Pain Relief Medicine with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 100 Coated Tablets

Advil Pain Reliever and Fever Reducer is a pain relief medicine with Ibuprofen 200mg that targets pain at the sight of inflammation. It provides longer-lasting relief than Tylenol Extra Strength and comes in a new packaging that is eco-friendly. It is easy to swallow and provides relief for up to 6 hours. It is suitable for adults and children 12 years and older for headache, backache, menstrual pain, joint pain, minor arthritis pain, muscle aches, and fever.

What We Like
Fast pain relief
Reliable ibuprofen formula
Good value for money
Convenient Amazon delivery
Long expiration date
#TOP 3

Timely Ibuprofen 200mg 500 Tablets

Timely Ibuprofen 200mg 500 Tablets Cover
TIME-Cap Labs 500 Tablets Ibuprofen 200mg Coated - Pain Reliever & Fever Reducer (NSAID) for Adults, Helps with Headache, Back Pain, Muscle Aches, Toothaches, Menstrual Cramps & Minor Arthritis Pain

Timely Ibuprofen 200mg 500 Tablets are full-strength pain relief pills that also reduce fever for adults and children over 12. They offer the same quality as more expensive products and are easy to use. With 500 tablets per bottle, you'll have enough pain relief for months to come.

What We Like
Consistent effectiveness
Affordable price
Large quantity
Comparable to name brands
Easy-to-take coated tablets
#TOP 4

Motrin IB 225 Ct Tablets for Pain Relief

300450481627
Motrin IB 225 Ct Tablets for Pain Relief Cover
Motrin IB Ibuprofen 200mg Tablets, Ibuprofen Pain & Fever Reliever for Headache, Backache, Muscular Aches, Menstrual Pain & Minor Arthritis Pain, Over-The-Counter NSAID Medicine, 225 ct

Get effective pain relief from minor aches and pains, fever, headache, backache, and menstrual cramps with Motrin IB tablets. Each 200-milligram tablet contains the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen to help stop pain at its source. Safe and effective for ages 12 years and older when used as directed, take one tablet every 4 to 6 hours while symptoms persist, up to 6 caplets in 24 hours.

What We Like
Affordable price
Effective pain relief
FSA eligible
Convenient delivery
Long-lasting supply

Amazon Basic Care Ibuprofen Tablets, 200 mg, 100 Count

Amazon Basic Care
White
Amazon Basic Care Ibuprofen Tablets, 200 mg, 100 Count Cover
Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Arthritis, Toothache, Backache and More, 100 Count

Amazon Basic Care Ibuprofen Tablets are a gluten-free pain reliever and fever reducer containing 200 mg of ibuprofen, providing temporary relief to minor aches and pains including headache, muscular ache, minor arthritis pain, toothache, backache, menstrual cramps, and fever. These coated caplets are approved for adults and children aged 12 and over.

What We Like
Affordable price
Effective pain relief
Comparable to name brand
Easy to swallow pills
Convenient online purchase

Advil Dual Action Back Pain Caplets - 144 Count

F00573014589
Advil Dual Action Back Pain Caplets - 144 Count Cover
Advil Dual Action Back Pain Caplets Delivers 125mg Ibuprofen and 250mg Acetaminophen Per Dose for 8 Hours of Back Pain Relief - 144 Count

Advil Dual Action Back Pain Caplets provide 8 hours of back pain relief with a lower maximum daily dose of each medication. The medication contains 250mg Ibuprofen and 500mg Acetaminophen to fight back pain 2 ways. Acetaminophen blocks pain signals and ibuprofen targets pain caused by inflammation. It also provides relief for headache, toothache, menstrual cramp, muscle pain and lower back pain.

What We Like
Provides 8 hours of back pain relief
Fights back pain 2 ways with Ibuprofen and Acetaminophen
Relieves headache, toothache, menstrual cramp, muscle pain and lower back pain
#TOP 7

Amazon Basic Care Children's Ibuprofen Chewable Tablets

Amazon Basic Care
Orange
Amazon Basic Care Children's Ibuprofen Chewable Tablets Cover
Amazon Basic Care Children's Ibuprofen Chewable Tablets, Pain Reliever and Fever Reducer, Orange Flavor, Ages 2-11, Lasts up to 8 Hours, 100 mg, 24 Count

Amazon Basic Care Children's Ibuprofen Chewable Tablets are a nonsteroidal anti-inflammatory drug (NSAID) that temporarily relieves minor aches and pains due to the common cold, flu, sore throat, headaches and toothaches; also helps to temporarily reduce fever. The chewable orange-flavored ibuprofen tablets are appropriate for children ages 2 to 11 years, and provide relief that lasts up to 8 hours. Plus, they are dye-free, preservative-free, and gluten-free.

What We Like
Pain reliever and fever reducer
Convenient chewable tablets require no water
Orange-flavored, making medicine easier to take for children

A+Health Mini Ibuprofen 200 Mg Softgels, 500 Count

IBU-MINI500
Soft Gel
A+Health Mini Ibuprofen 200 Mg Softgels, 500 Count Cover
A+Health Mini Ibuprofen 200 Mg Softgels, Pain Reliever/Fever Reducer (NSAID), 500 Count

A+Health Mini Ibuprofen 200 Mg Softgels are 25% smaller than regular Ibuprofen Softgels, providing fast-acting pain relief for headaches, backaches, toothaches, menstrual cramps, and more. These liquid-filled capsules are easy to swallow, containing active ingredient Ibuprofen 200mg, and temporarily reduce fever and relieve minor aches and pains due to various reasons. Proudly made in the USA, the 500-count bottle is perfect for on-the-go relief.

What We Like
Effective for headaches and fever
Inexpensive option
Easy to swallow
Smaller size than regular gel caps
Comparable to name brands

Advil Liqui-Gels Minis

305731769890
Advil Liqui-Gels Minis Cover
Advil Liqui-Gels Minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 160 Liquid Filled Capsules

Advil Minis are a pain reliever and fever reducer designed for fast absorption. With the same strength as regular size Advil Liqui-Gels, these 200mg ibuprofen capsules provide faster and stronger relief for tough pain, such as headaches, back pain, joint pain, and minor arthritis pain. The new packaging of Advil Minis features 20 percent less plastic, helping to keep nearly 500,000 pounds of plastic out of landfills. Additionally, the smaller capsule size of these Liqui-Gels makes them more convenient to swallow. Suitable for adults and children 12 years and older, Advil Minis offer effective relief for various types of pain and fever.

What We Like
Faster and stronger pain relief
20 percent less plastic in packaging
Convenient smaller capsule size
#TOP 10

Motrin IB 200mg Ibuprofen Liquid Gel Pain Reliever/Fever Reducer for Pain Relief, 120 Ct

300450409126
Motrin IB 200mg Ibuprofen Liquid Gel Pain Reliever/Fever Reducer for Pain Relief, 120 Ct Cover
Motrin IB Liquid Gels with 200mg Ibuprofen per Caplet, Pain Reliever & Fever Reducer for Adults, Relief from Minor Arthritis Pain, Muscle Aches, Headache, Menstrual Cramps & Backache, 120 ct

Motrin IB Liquid Gels is a fast-acting pain reliever and fever reducer that comes in a 120-count bottle. Each liquid gel contains 200 milligrams of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that can help relieve pain and reduce fever resulting from common cold, headache, backache, toothache, menstrual cramps, and minor pain of arthritis. It is safe and effective for ages 12 years and older, and can provide long-lasting relief when used as directed. Adults and children 12 years and older can take one capsule every 4 to 6 hours while symptoms persist, and up to 6 capsules in 24 hours unless directed by a doctor.

What We Like
Fast-acting pain relief
Effective fever reducer
Contains 120 liquid gels
Buying Guide Image

Frequently Asked Questions (FAQs)

1. How much ibuprofen can I take for a migraine?

Conclusions: Ibuprofen at doses of 200 mg and 400 mg is an efficacious, cost-effective, well-tolerated, single-ingredient nonprescription treatment for pain of migraine headache.

2. Which ibuprofen is best for migraine?

Many people who have migraines find that over-the-counter painkillers, such as paracetamol, aspirin and ibuprofen, can help to reduce their symptoms. They tend to be most effective if taken at the first signs of a migraine attack, as this gives them time to absorb into your bloodstream and ease your symptoms.

3. Can ibuprofen make migraines worse?

A variety of medications can lead to rebound headaches. For example, people with migraine who take over-the-counter pain-relieving medications such as acetaminophen (Tylenol), ibuprofen (Advil, Motrin), or naproxen (Aleve) on more than 15 days per month are at risk for medication overuse headache.

4. Is ibuprofen or Tylenol better for migraines?

Both ibuprofen and acetaminophen are effective and economical treatments for severe or moderate migraine attacks in children. Ibuprofen gave the best relief.

Editor's Notes

During our ibuprofen for migraine research, we found 24 ibuprofen for migraine products and shortlisted 10 quality products. We collected and analyzed 403,463 customer reviews through our big data system to write the ibuprofen for migraine list. We found that most customers choose ibuprofen for migraine with an average price of $11.44.

The ibuprofen for migraine are available for purchase. We have researched hundreds of brands and picked the top brands of ibuprofen for migraine, including Advil, TIME-CAP LABS, INC., Motrin, A+Health. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.