Best Ibuprofen for Cramps of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 18, 2026

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Ibuprofen is a widely used pain reliever that can help alleviate menstrual cramps. This over-the-counter medication works by reducing inflammation in the body, which can help to ease the discomfort associated with menstrual cramps. Ibuprofen is available in various strengths and forms, including tablets, capsules, and liquid gels. It is important to follow the recommended dosage instructions and to consult with a healthcare provider before taking any new medications. With its proven effectiveness and availability, Ibuprofen is a popular choice for those seeking relief from menstrual cramps.

At a Glance: Our Top Picks

Timely Ibuprofen 200mg 500 Tablets Cover #TOP 1
Timely Ibuprofen 200mg 500 Tablets
ftb score rating icon 9.9
Amazon Basic Care Ibuprofen Tablets, 500 Count Cover #TOP 2
Amazon Basic Care Ibuprofen Tablets, 500 Count
ftb score rating icon 9.8
Motrin IB 225 Ct Tablets for Pain Relief Cover #TOP 3
Motrin IB 225 Ct Tablets for Pain Relief
ftb score rating icon 9.6

Top 10 Ibuprofen for Cramps

Timely Ibuprofen 200mg 500 Tablets

Timely Ibuprofen 200mg 500 Tablets Cover
TIME-Cap Labs 500 Tablets Ibuprofen 200mg Coated - Pain Reliever & Fever Reducer (NSAID) for Adults, Helps with Headache, Back Pain, Muscle Aches, Toothaches, Menstrual Cramps & Minor Arthritis Pain

Timely Ibuprofen 200mg 500 Tablets are full-strength pain relief pills that also reduce fever for adults and children over 12. They offer the same quality as more expensive products and are easy to use. With 500 tablets per bottle, you'll have enough pain relief for months to come.

What We Like
Consistent effectiveness
Affordable price
Large quantity
Comparable to name brands
Easy-to-take coated tablets
#TOP 2

Amazon Basic Care Ibuprofen Tablets, 500 Count

Amazon Basic Care
B074F297T8
Amazon Basic Care Ibuprofen Tablets, 500 Count Cover
Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)

Amazon Basic Care Ibuprofen Tablets are a pain reliever and fever reducer that contain 200 mg of ibuprofen, providing strong relief for tough pain such as muscular aches, minor arthritis pain, toothache, backache, menstrual cramps or minor aches and pains from the common cold. These tablets are effective for adults and children over 12 years old and are comparable to Advil Ibuprofen Tablets. Ibuprofen is the number one doctor recommended back pain OTC active ingredient.

What We Like
Affordable price
Comparable to name brands
Large quantity per bottle
Fast pain relief
Easy to swallow tablets
#TOP 3

Motrin IB 225 Ct Tablets for Pain Relief

300450481627
Motrin IB 225 Ct Tablets for Pain Relief Cover
Motrin IB Ibuprofen 200mg Tablets, Ibuprofen Pain & Fever Reliever for Headache, Backache, Muscular Aches, Menstrual Pain & Minor Arthritis Pain, Over-The-Counter NSAID Medicine, 225 ct

Get effective pain relief from minor aches and pains, fever, headache, backache, and menstrual cramps with Motrin IB tablets. Each 200-milligram tablet contains the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen to help stop pain at its source. Safe and effective for ages 12 years and older when used as directed, take one tablet every 4 to 6 hours while symptoms persist, up to 6 caplets in 24 hours.

What We Like
Affordable price
Effective pain relief
FSA eligible
Convenient delivery
Long-lasting supply

A+Health Ibuprofen 200mg Softgels, 300 Count

IBU300
Blue
300 Count
A+Health Ibuprofen 200mg Softgels, 300 Count Cover
A+Health Ibuprofen 200 Mg Softgels, Pain Reliever/Fever Reducer (NSAID), 300 Count

Get temporary pain relief with A+Health Ibuprofen 200mg Softgels, which contains active ingredient Ibuprofen 200mg. These liquid-filled capsules are easy to swallow and provide relief from minor aches and pains including headache, toothache, menstrual cramps, backache, muscular aches, and minor pain of arthritis. Proudly made in the USA, this 300-count bottle is a great value. Don't let pain get in your way, find relief with A+ Health Ibuprofen 200mg Softgels.

What We Like
Cost-effective alternative
Easy on the stomach
Larger gel tab size
Value-priced larger bottles
High dissolvability

Amazon Basic Care Ibuprofen Tablets, 200 mg, 100 Count

Amazon Basic Care
White
Amazon Basic Care Ibuprofen Tablets, 200 mg, 100 Count Cover
Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Arthritis, Toothache, Backache and More, 100 Count

Amazon Basic Care Ibuprofen Tablets are a gluten-free pain reliever and fever reducer containing 200 mg of ibuprofen, providing temporary relief to minor aches and pains including headache, muscular ache, minor arthritis pain, toothache, backache, menstrual cramps, and fever. These coated caplets are approved for adults and children aged 12 and over.

What We Like
Affordable price
Effective pain relief
Comparable to name brand
Easy to swallow pills
Convenient online purchase
#TOP 6

Motrin Dual Action with Tylenol

JO031112
White
120 Count
Motrin Dual Action with Tylenol Cover
Motrin Dual Action with Tylenol, Ibuprofen & Acetaminophen Fast-Acting Dual Action Pain Reliever for Minor Aches & Pains, Ibuprofen (NSAID) 125 mg & Acetaminophen 250 mg, 120 ct

Motrin Dual Action with Tylenol is a 2-in-1 pain reliever medicine designed to temporarily relieve minor aches and pains due to headache, toothache, backache, menstrual pains, period cramps, muscle aches, and minor pain caused by arthritis. Each tablet contains 250 mg acetaminophen plus 125 mg ibuprofen to provide dual action pain relief. It is intended for adults and children 12 years of age and older, and should be taken every 8 hours while symptoms persist. Please note that severe liver damage may occur if taken with other drugs containing acetaminophen.

What We Like
Provides dual action pain relief
Effective for minor aches and pains
Designed for adults and children 12 years of age and older
#TOP 7

Amazon Basic Care Ibuprofen Tablets, 200 mg

Amazon Basic Care
Amazon Basic Care Ibuprofen Tablets, 200 mg Cover
Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Headache, Muscular Aches, Arthritis, Backache and More, 100 Count (Pack of 1)

Amazon Basic Care Ibuprofen Tablets contain 200 mg of ibuprofen, a pain reliever and fever reducer that can be used to alleviate minor aches and pains caused by headache, muscular aches, arthritis, toothache, backache, the common cold, and menstrual cramps. Ibuprofen is the top doctor-recommended OTC active ingredient for back pain. These gluten-free coated tablets are a proven pain relief without a prescription.

What We Like
Relieves minor aches and pains caused by various conditions
Contains 200 mg of ibuprofen, a proven pain reliever and fever reducer
Doctor-recommended OTC active ingredient for back pain
Coated tablets are gluten-free
#TOP 8

Motrin IB 200mg Ibuprofen Liquid Gel Pain Reliever/Fever Reducer for Pain Relief, 120 Ct

300450409126
Motrin IB 200mg Ibuprofen Liquid Gel Pain Reliever/Fever Reducer for Pain Relief, 120 Ct Cover
Motrin IB Liquid Gels with 200mg Ibuprofen per Caplet, Pain Reliever & Fever Reducer for Adults, Relief from Minor Arthritis Pain, Muscle Aches, Headache, Menstrual Cramps & Backache, 120 ct

Motrin IB Liquid Gels is a fast-acting pain reliever and fever reducer that comes in a 120-count bottle. Each liquid gel contains 200 milligrams of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that can help relieve pain and reduce fever resulting from common cold, headache, backache, toothache, menstrual cramps, and minor pain of arthritis. It is safe and effective for ages 12 years and older, and can provide long-lasting relief when used as directed. Adults and children 12 years and older can take one capsule every 4 to 6 hours while symptoms persist, and up to 6 capsules in 24 hours unless directed by a doctor.

What We Like
Fast-acting pain relief
Effective fever reducer
Contains 120 liquid gels

Advil Dual Action Back Pain Caplets - 144 Count

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Advil Dual Action Back Pain Caplets - 144 Count Cover
Advil Dual Action Back Pain Caplets Delivers 125mg Ibuprofen and 250mg Acetaminophen Per Dose for 8 Hours of Back Pain Relief - 144 Count

Advil Dual Action Back Pain Caplets provide 8 hours of back pain relief with a lower maximum daily dose of each medication. The medication contains 250mg Ibuprofen and 500mg Acetaminophen to fight back pain 2 ways. Acetaminophen blocks pain signals and ibuprofen targets pain caused by inflammation. It also provides relief for headache, toothache, menstrual cramp, muscle pain and lower back pain.

What We Like
Provides 8 hours of back pain relief
Fights back pain 2 ways with Ibuprofen and Acetaminophen
Relieves headache, toothache, menstrual cramp, muscle pain and lower back pain
#TOP 10

HealthA2Z Ibuprofen 200mg Tablets

TS0417-B700ML-M993
500 Count
HealthA2Z Ibuprofen 200mg Tablets Cover
HealthA2Z® Ibuprofen 200mg | 500 Counts | Pain Relief | Body Aches | Headache | Arthritis | Cramps | Back Pain | Fever Reducer… (500 Count)

HealthA2Z Ibuprofen 200mg Tablets are a pain reliever and fever reducer with fast relief medicine for pain, preventing pain before it starts and alleviating pain after initial prostaglandin production. It can reduce your body's temperature to avoid damage to itself, and contains the same active ingredient as name brands at a fraction of the cost. Adults can take 1 tablet every 4 to 6 hours, not exceeding 6 tablets in 24 hours unless directed by doctors.

What We Like
Fast Relief Medicine for Pain
Fever Reducer
Same Active Ingredient as Name Brands
Buying Guide Image

Frequently Asked Questions (FAQs)

1. How much ibuprofen can I take for cramps?

For menstrual cramps: Adults—400 milligrams (mg) every four hours, as needed. Children—Use and dose must be determined by your doctor .

2. Can I take 2 ibuprofen for period cramps?

Ibuprofen for Pain: Give 2 ibuprofen 200 mg tablets 3 times per day for 3 days. The first dose should be 3 tablets (600 mg) if the teen weighs over 100 pounds (45 kg). Take with food. Ibuprofen is a very good drug for cramps.

3. Why is ibuprofen better for menstrual cramps?

Although acetaminophen (Tylenol) and ibuprofen (Motrin or Advil) both relieve menstrual pain, ibuprofen is the more effective of the two because of its anti-inflammatory properties. The recommendation is to take 400 mg of ibuprofen every six to eight hours for the first few days of a period.

4. Can I take ibuprofen 800 mg for cramps?

“800 mg ibuprofen, AN ACTUAL LIFESAVER for my period pain. I have detrimental pain each time my period comes, to the point where it arouses fear in me. Ibuprofen really helps, takes minutes for relief. I'm extremely dependent though and usually take 1 or 2 a day, for the first 4 days of my period.”

Editor's Notes

During our ibuprofen for cramps research, we found 24 ibuprofen for cramps products and shortlisted 10 quality products. We collected and analyzed 654,144 customer reviews through our big data system to write the ibuprofen for cramps list. We found that most customers choose ibuprofen for cramps with an average price of $13.06.

The ibuprofen for cramps are available for purchase. We have researched hundreds of brands and picked the top brands of ibuprofen for cramps, including TIME-CAP LABS, INC., Motrin, A+Health, Advil, HealthA2Z. The seller of top 1 product has received honest feedback from 3,170 consumers with an average rating of 4.9.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.