Best Ibuprofen for Sleep Aid of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 5, 2025

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Ibuprofen is a commonly used pain reliever, but did you know that it can also be used as a sleep aid? Ibuprofen can help alleviate pain and reduce inflammation, which can make it easier to fall asleep and stay asleep throughout the night. While it's not a traditional sleep aid, many people find that taking ibuprofen before bed can help them get a better night's rest. However, it's important to talk to a doctor or pharmacist before using ibuprofen for sleep, as there are potential side effects and interactions to be aware of.

At a Glance: Our Top Picks

Amazon Basic Care Ibuprofen PM, Pain Reliever/Nighttime Sleep-Aid, 120 Count Cover #TOP 1
Amazon Basic Care Ibuprofen PM, Pain Reliever/Nighttime Sleep-Aid, 120 Count
ftb score rating icon 9.9
Advil PM Pain Reliever & Sleep Aid Cover #TOP 2
Advil PM Pain Reliever & Sleep Aid
ftb score rating icon 9.8
A+Health Ibuprofen PM Softgels, 120 Count Cover #TOP 3
A+Health Ibuprofen PM Softgels, 120 Count
ftb score rating icon 9.6

Top 10 Ibuprofen for Sleep Aid

Amazon Basic Care Ibuprofen PM, Pain Reliever/Nighttime Sleep-Aid, 120 Count

Amazon Basic Care
Amazon Basic Care Ibuprofen PM, Pain Reliever/Nighttime Sleep-Aid, 120 Count Cover
Amazon Basic Care Ibuprofen PM, Ibuprofen 200 mg and Diphenhydramine Citrate 38 mg Tablets, Pain Reliever and Nighttime Sleep-Aid, 120 Count (Packaging may vary)

Amazon Basic Care Ibuprofen PM is a pain reliever (NSAID) and nighttime sleep-aid. It contains ibuprofen 200 mg and diphenhydramine citrate 38 mg, providing relief of occasional sleeplessness when associated with minor aches and pains. This product is intended for adults and children 12 years and over, and is gluten free.

What We Like
Combines pain relief and nighttime sleep-aid
Contains ibuprofen 200 mg and diphenhydramine citrate 38 mg
Relieves occasional sleeplessness when associated with minor aches and pains
Suitable for adults and children 12 years and over
Gluten free
#TOP 2

Advil PM Pain Reliever & Sleep Aid

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Advil PM Pain Reliever & Sleep Aid Cover
Advil PM Pain Reliever and Nighttime Sleep Aid, Ibuprofen for Pain Relief and Diphenhydramine Citrate for a Sleep Aid - 120 Coated Caplets and Pain Reliever and Fever Reducer, 10 Count Tablets

Advil PM Sleep Aid combines pain relief and sleep support in one easy-to-use product. It contains ibuprofen, which helps alleviate various types of pain, including headaches, backaches, and menstrual discomfort. Additionally, the diphenhydramine citrate in the formula aids in falling asleep, making it ideal for those who struggle with occasional sleeplessness due to minor aches. With a convenient dosage of just two caplets at bedtime, this product is perfect for adults and children aged 12 and older. Plus, it’s a great option for those sensitive to melatonin, providing a safe way to help you rest without sleep hormones.

What We Like
Effective pain relief
Helps with sleep
Convenient dosage
No melatonin
#TOP 3

A+Health Ibuprofen PM Softgels, 120 Count

IBUPM120
Blue
A+Health Ibuprofen PM Softgels, 120 Count Cover
A+Health Ibuprofen PM Softgels, Pain Reliever/Nighttime Sleep Aid (NSAID), Made in USA, 120 Count

A+Health Ibuprofen PM Softgels are a pain reliever and nighttime sleep aid that are made in the USA. The softgels contain active ingredients including Ibuprofen and Diphenhydramine, which can temporarily reduce fever and relieve minor aches and pains. The medication is designed to help those who have difficulty swallowing pills, and can provide relief from occasional sleeplessness when associated with minor aches and pains. The product comes with 120 softgels.

What We Like
Provides temporary relief from common pain and sleeplessness
Softgels are easier to swallow than traditional pills
Contains active ingredients Ibuprofen and Diphenhydramine
#TOP 4

Motrin PM Caplets, 200mg Ibuprofen & 38mg Sleep Aid, Night Relief, 80 ct.

Motrin PM Caplets, 200mg Ibuprofen & 38mg Sleep Aid, Night Relief, 80 ct. Cover
Motrin PM Caplets, 200 mg Ibuprofen & 38 mg Sleep Aid, Nighttime Relief for Minor Pains, 80 ct.

Motrin PM Caplets are an effective pain reliever with a gentle sleep aid to help ease today's aches, enabling you to fall asleep and stay asleep. This nighttime pain reliever is targeted for arthritis, headache, backache, and menstrual cramps, and provides relief from occasional sleeplessness. The caplets contain 200mg of ibuprofen and a gentle sleep-aid to stop pain at its source, and are safe for ages 12 and over as directed. Motrin PM is an ideal remedy to help you feel rested and ready to tackle the next day.

What We Like
Contains ibuprofen and gentle sleep-aid to provide effective pain relief and promote sleep
Relieves pain associated with arthritis, headache, backache, and menstrual cramps
Safe and effective for ages 12 and over when used as directed
#TOP 5

Advil Pain Reliever and Fever Reducer, Ibuprofen 200mg for Pain Relief - 300 Count

F00573171754
2 Piece Set
Advil Pain Reliever and Fever Reducer, Ibuprofen 200mg for Pain Relief - 300 Count Cover
Advil Pain Reliever and Fever Reducer, Ibuprofen 200mg for Pain Relief - 300 Count, Advil PM Pain Reliever and Nighttime Sleep Aid, Ibuprofen for Pain Relief and Diphenhydramine Citrate - 2 Count

Advil Pain Reliever and Fever Reducer is a coated ibuprofen 200mg pain reliever that can provide relief for back pain, headaches, arthritis, and other types of pain. The bottle contains 300 coated tablets, which are easy to swallow and can last for up to 6 hours. The packaging now features 20% less plastic to reduce plastic waste. In addition, the Advil PM Pain Reliever and Nighttime Sleep Aid Caplets can provide restful sleep and relief for headaches, arthritis pain, joint pain, and occasional sleeplessness related to minor aches and pains.

What We Like
Provides relief for various types of pain
300 count bottle lasts for up to 6 hours
Advil PM Caplets provide restful sleep and relief for headaches, arthritis pain, joint pain, and occasional sleeplessness
#TOP 6

Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid

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Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid Cover
Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine HCL for a Sleep Aid - 40 Liquid Filled Capsules - Back to College

Advil PM Liqui-Gels is a pain reliever and nighttime sleep aid with Ibuprofen and Diphenhydramine HCL. This medicine helps relieve occasional sleeplessness related to minor aches and pains, headache, minor arthritis pain, and back pain. The liquid-filled capsules rush relief right where it hurts and help you fall asleep and stay asleep. The new packaging will feature 20% less plastic to keep nearly 500,000 pounds of plastic out of landfills.

What We Like
Effective pain relief and sleep aid
Fast-acting liquid relief
Relieves headache, minor arthritis pain, and back pain
New packaging with 20% less plastic
#TOP 7

Advil PM Liqui-Gels

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Advil PM Liqui-Gels Cover
Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine HCL for a Sleep Aid - 80 Liquid Filled Capsules - Back to College

Advil PM Liqui-Gels is a pain reliever and nighttime sleep aid medicine by Advil. It contains Ibuprofen for pain relief and Diphenhydramine HCL for a sleep aid. This product is suitable for adults and children who are 12 years and older. It can relieve occasional sleeplessness related to minor aches and pains such as headache, arthritis pain, and back pain. To use Advil PM, take two of these liquid filled capsules at bedtime. The product is HSA and FSA eligible. Moreover, Advil is committed to reducing plastic waste, and by 2022, the new packaging will feature 20% less plastic, keeping nearly 500,000 pounds of plastic out of landfills.

What We Like
Pain relief
Sleep aid
Reduces plastic waste
#TOP 8

Advil PM Pain Reliever and Nighttime Sleep Aid, Pain Medicine - 50x2 Coated Caplets

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Advil PM Pain Reliever and Nighttime Sleep Aid, Pain Medicine - 50x2 Coated Caplets Cover
Advil PM Pain Reliever and Nighttime Sleep Aid, Pain Medicine with Ibuprofen for Pain Relief and Diphenhydramine Citrate for a Sleep Aid - 50x2 Coated Caplets

Advil PM Pain Reliever and Nighttime Sleep Aid is a pain medicine with ibuprofen for pain relief and diphenhydramine citrate for a sleep aid. It comes in 50 packets of 2 coated caplets, which can help you relieve occasional sleeplessness related to minor aches and pains. The ibuprofen PM sleep aid and nighttime pain reliever is also portable, making it perfect for use at home or away. The new packaging will feature 20% less plastic, which helps keep nearly 500,000 pounds of plastic out of landfills by 2022.

What We Like
Relieves occasional sleeplessness related to minor aches and pains
Helps you fall asleep and stay asleep
Portable for use at home or away
New packaging features 20% less plastic
#TOP 9

Advil PM Pain Reliever/Nighttime Sleep Aid Caplets

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Advil PM Pain Reliever/Nighttime Sleep Aid Caplets Cover
Advil PM (20 Count) Pain Reliever/Nighttime Sleep Aid Coated Caplet, 200mg Ibuprofen, 38mg Diphenhydramine

Advil PM is a dual-layer coated caplet that helps relieve occasional sleeplessness and minor aches and pains, allowing you to fall asleep faster and stay asleep longer. Its bi-layer patented formula combines Ibuprofen, the world's No.1 OTC pain reliever, with Diphenhydramine, the No.1 soothing sleep aid, providing safe and effective pain relief for over 30 years. The product is safe, gentle, and non-habit forming, with two active ingredients that have a long history of safe and effective treatment when used as directed.

What We Like
Helps you fall asleep faster and stay asleep longer
Dual-layer patented formula for effective pain relief
Safe, gentle, and non-habit forming
#TOP 10

Advil PM Pain Reliever and Nighttime Sleep Aid - 120 Caplets

305730164436
Other
120 Coated Caplets
Advil PM Pain Reliever and Nighttime Sleep Aid - 120 Caplets Cover
Advil PM Pain Reliever/Nighttime Sleep Aid Coated Caplet, 200mg Ibuprofen, 38mg Diphenhydramine, Other, 120 Count

Advil PM Pain Reliever and Nighttime Sleep Aid is a medication that offers relief from occasional sleeplessness, minor aches, and pains. It is a nighttime sleep aid and pain medication that helps you fall asleep and stay asleep. The medication is portable, so you can take it with you wherever you go. The new packaging features 20 percent less plastic, which helps keep nearly 500,000 pounds of plastic out of landfills by 2022.

What We Like
Offers relief from occasional sleeplessness, minor aches, and pains
Helps you fall asleep and stay asleep
Portable, making it easy to take with you
Uses 20% less plastic in its new packaging, helping to reduce plastic waste
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is there an ibuprofen sleep aid?

NIGHTTIME SLEEP AID: Ibuprofen and Diphenhydramine Citrate Tablets, 200 mg/38 mg contain a combination of a nighttime sleep-aid and a pain reliever (NSAID) that provides relief of occasional sleeplessness when associated with minor aches and pains.

2. Does ibuprofen 800mg make you sleep?

Can ibuprofen (Advil) make you sleepy? No. Drowsiness is not a known side effect of ibuprofen (Advil).

3. Is ibuprofen good to take before bed?

According to a new study, published in the journal Scientific Reports, using NSAIDs during the daytime might be preferable to taking them at night (such as before bed).

4. What is in ibuprofen PM that makes you sleep?

A: Ibuprofen p.m. is a combination medication that contains ibuprofen and diphenhydramine. Diphenhydramine is the active ingredient in Benadryl, an antihistamine taken for allergies. The ibuprofen will help easy any aches or pains. The diphenhydramine makes most people drowsy.

Editor's Notes

During our ibuprofen for sleep aid research, we found 24 ibuprofen for sleep aid products and shortlisted 10 quality products. We collected and analyzed 148,246 customer reviews through our big data system to write the ibuprofen for sleep aid list. We found that most customers choose ibuprofen for sleep aid with an average price of $18.91.

The ibuprofen for sleep aid are available for purchase. We have researched hundreds of brands and picked the top brands of ibuprofen for sleep aid, including Advil, A+Health, TENA. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.