Best Goldenseal Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 23, 2026

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Goldenseal supplements are a popular natural remedy that have been used for centuries. These supplements are derived from a plant called Hydrastis canadensis, which is native to North America. Goldenseal supplements are known for their anti-inflammatory, antibacterial, and antifungal properties. They are often used to treat a variety of health conditions, including digestive issues, respiratory infections, and skin problems. Additionally, goldenseal supplements are believed to boost the immune system and promote overall wellness. These supplements come in various forms, including capsules, tinctures, and teas, making them a convenient and easy-to-use natural remedy.

At a Glance: Our Top Picks

Integrative Therapeutics Berberine Complex Cover #TOP 1
Integrative Therapeutics Berberine Complex
ftb score rating icon 9.8
Integrative Therapeutics Berberine Capsules Cover #TOP 2
Integrative Therapeutics Berberine Capsules
ftb score rating icon 9.7
Nature's Way Goldenseal Herb Cover #TOP 3
Nature's Way Goldenseal Herb
ftb score rating icon 9.5

Top 10 Goldenseal Supplements

#TOP 1

Integrative Therapeutics Berberine Complex

Integrative Therapeutics Berberine Complex Cover
Integrative Therapeutics Berberine Complex - Digestive & Gut Health Supplement* - Vegan, Gluten-Free & Dairy-Free - 90 Capsules (45 Servings)

Integrative Therapeutics Berberine Complex is a traditional gastrointestinal support supplement that contains Barberry, Oregon Grape, and Goldenseal Root Extract. This supplement is formulated to support the healthy balance of bacteria in the digestive tract. It is gluten-free, vegan, and contains no salt, wheat, or artificial colors, flavors, or preservatives. Berberine Complex is an excellent choice for those looking to support their digestive health.

What We Like
Blood sugar support
Gut health improvement
Natural ingredients
Easy to take
Weight management
What We Don't Like
Possible stomach discomfort
Not effective for everyone
#TOP 2

Integrative Therapeutics Berberine Capsules

Integrative Therapeutics Berberine Capsules Cover
Integrative Therapeutics Berberine - Supports Metabolic Health & Cellular Energy Metabolism - Practitioner-Trusted Quality - Dairy-Free & Gluten-Free - 120 Capsules (120 Servings)

The Integrative Therapeutics Berberine supplement is designed to support your body's metabolism and energy production naturally. It helps maintain healthy digestion and ensures your body efficiently processes fats and carbohydrates, which can aid in overall metabolic health. This supplement also promotes balanced cholesterol levels, contributing to heart health. Made without common allergens like gluten, dairy, soy, and artificial additives, it fits easily into your daily routine without worry. If you're looking for a trusted, high-quality product to support your metabolic wellness, this Berberine supplement offers a convenient and effective option.

What We Like
Blood sugar reduction
Cholesterol improvement
Appetite control
Weight management support
Trusted by doctors
What We Don't Like
Mild digestive discomfort
Short half-life for some
#TOP 3

Nature's Way Goldenseal Herb

13700
Nature's Way Goldenseal Herb Cover
Nature's Way Goldenseal, Traditional Herb, 700 mg per 2-Capsule Serving, Non-GMO Project Verified, Vegan, 100 Capsules

Nature's Way Premium Herbal Goldenseal Herb is a traditional Native American remedy, guaranteed to contain 1.5% total alkaloids. It is Non-GMO Project and Tru-ID Certified, with 800 mg per serving and suitable for vegetarians and those with gluten-free diets. Customers have praised its effectiveness for healing infections, prostate issues, and more.

What We Like
Fast sinus relief
Natural remedy
Effective for infections
Reliable cold season support
What We Don't Like
Hard to find
#TOP 4

Nutricost Goldenseal Root 600mg

NTC172101
Nutricost Goldenseal Root 600mg Cover
Nutricost Goldenseal Root 600mg, 120 Capsules - Non-GMO, Gluten Free, Vegetarian Capsules

Nutricost Goldenseal Root 600mg is a non-GMO, gluten free, and vegetarian capsule supplement that provides 600mg of Goldenseal Root per serving. Each bottle contains 120 servings, with just 1 easy to take capsule per serving. It is manufactured in a GMP compliant, FDA registered facility. Customers have reported that it helps with tinnitus, urinary tract infections, boosting the immune system, and sore throats.

What We Like
Effective for infections
Consistent high quality
Antibacterial properties
Helpful for sinusitis
What We Don't Like
Inconsistent powder color
Variable absorption
#TOP 5

CEALMU CORE Liposomal Berberine 1500mg

CEALMU CORE
CaelumCore1-1
CEALMU CORE Liposomal Berberine 1500mg Cover
CEALMU CORE Liposomal Berberine HCL - Berberine 1500mg Activates AMPK, High Bioavailability Berberines Supplement for Women and Men, Supports Body Balance

The CEALMU CORE Berberine supplement uses advanced liposomal technology to help your body absorb more of the active ingredients, making the supplement more effective. It undergoes third-party lab testing, so you can trust its purity and safety. Each capsule provides a strong 1500mg dose, offering reliable daily support for your health. Additionally, this supplement helps activate AMPK, known as the body’s natural energy switch, which supports balanced body functions and better nutrient use. Together, these features give you a powerful and trustworthy option to support your overall wellness.

What We Like
Appetite suppression
Increased energy
Weight loss support
Improved gut health
Easy to take
What We Don't Like
Possible stomach discomfort
Results may vary
#TOP 6

Vimergy USDA Organic Goldenseal Extract

GOLDEN-115
Vimergy USDA Organic Goldenseal Extract Cover
Vimergy USDA Organic Goldenseal Tincture Herbal Supplement – (57 Servings) – Vegan, Alcohol-Free Golden Seal herb Drops Great for Tea (115 mL)

Vimergy USDA Organic Goldenseal Extract is a potent 10:1 water extracted alcohol-free formula made with USDA organic goldenseal, organic glycerin, and organic lemon juice. It contains 200 mg of organic goldenseal extract, equivalent to 2000mg of herbal extract. It is certified USDA Organic and Kosher, and is free of fillers, additives, citric acid, corn, soy, alcohol, or flavors. Customers have praised the product for its potency and clean ingredients, but some have noted a strong sour aftertaste.

What We Like
High product quality
Effective for multiple health issues
Pure ingredients
Fast symptom relief
Palatable taste
What We Don't Like
Somewhat expensive
Soap-like taste for some
#TOP 7

NOW Supplements Goldenseal Root

4690
Light Green
NOW Supplements Goldenseal Root Cover
NOW Supplements, Goldenseal Root (Hydrastis canadensis) 500 mg, Herbal Supplement, 50 Veg Capsules

NOW Supplements Goldenseal Root is a herbal supplement derived from the root of the Hydrastis canadensis plant. This wildcrafted product is Non-GMO, Dairy Free, Egg Free, Gluten Free, Nut Free, and Soy Free. It has been used traditionally by Native Americans for hundreds of years and is still used by modern herbalists today. Customers have reported positive results for topical antibiotic uses, sinus infections, minor respiratory problems, and colds/illnesses. NOW is a trusted brand for quality herbal supplements at a reasonable price.

What We Like
Natural antibiotic support
High quality ingredients
Effective for topical wounds
Immune system boost
No notable side effects
What We Don't Like
Slightly grainy texture
Color variation from other brands
#TOP 8

Carlyle Goldenseal Root Capsules

CL39506
Carlyle Goldenseal Root Capsules Cover
Carlyle Goldenseal Root Capsules 1000mg | 200 Count | Traditional Herb Supplement | Non-GMO, Gluten Free

Carlyle Goldenseal Root Capsules are a non-GMO, gluten-free supplement containing 1,000 mg of Goldenseal per serving. This traditional herb is known for its powerful rhizomes and plant alkaloids. Customers have found the capsules to be of good quality, easy to swallow, and effective. Some have even reported that it has saved their life! The only downside is that some customers found the flavor to be too weak.

What We Like
Natural antibiotic benefits
Improved hearing
Pain relief
Effective for multiple uses
No prescription antibiotics needed
What We Don't Like
Some may find price high
Dosage clarity needed
#TOP 9

Herb Pharm Organic Goldenseal Liquid Extract

090700000677
1 Fl Oz (Pack of 1)
Herb Pharm Organic Goldenseal Liquid Extract Cover
Herb Pharm Certified Organic Goldenseal Liquid Extract for Respiratory System Support, Organic Cane Alcohol, 1 Ounce

The Herb Pharm Goldenseal Extract is a liquid supplement designed to help support your respiratory and immune health. Because it’s in liquid form, it’s quickly absorbed and allows your senses of taste and smell to engage, which may help your body better recognize and use the herbal ingredients. This extract is made from certified organic Goldenseal roots grown on Herb Pharm’s own farm in southern Oregon, ensuring quality and purity. Plus, it’s vegan, non-GMO, and gluten-free, making it a suitable choice for many dietary preferences.

What We Like
High potency and effectiveness
Organically grown ingredients
Trusted quality control
Versatile uses for humans and pets
Long-lasting concentrated formula
What We Don't Like
Bitter taste
Mild stomach irritation
#TOP 10

Wild & Organic Goldenseal Tincture

4 Fl Oz (Pack of 1)
Wild & Organic Goldenseal Tincture Cover
Wild & Organic Goldenseal Tincture - Lung & Digestive Support - Goldenseal Root Extract Liquid Drops - Vegan, Sugar & Alcohol-Free Herb Supplement - 4 fl oz

Experience the full potential of goldenseal with Wild & Organic Goldenseal Drops. This concentrated liquid supplement showcases the remarkable qualities of goldenseal root. With a potent formula of 670 mg of goldenseal root per serving, this tincture offers enhanced absorption for maximum benefits. Made in the USA by a family-owned company, Wild & Organic, this goldenseal liquid extract is made from organic ingredients and is third-party tested for quality and efficacy. If you're looking for a high-quality goldenseal supplement, Wild & Organic Goldenseal Drops are the perfect choice.

What We Like
Fast relief for colds
Supports gall bladder health
Helps with UTI recovery
High product quality
Easy liquid absorption
What We Don't Like
Price could be lower
Buying Guide Image

Find Your Fit: How to Buy the Right Goldenseal Supplements

Why Choose Goldenseal Supplements?

Goldenseal is an herbal supplement that has been used for centuries by Native Americans for its numerous health benefits. It has a long history of being used to treat a wide range of ailments, including digestive issues, respiratory infections, and skin disorders. Today, goldenseal continues to be a popular herbal remedy, and many people take goldenseal supplements to help support their overall health and wellbeing.

The Benefits of Goldenseal

One of the primary reasons why people choose goldenseal supplements is because of their anti-inflammatory and antimicrobial properties. Goldenseal contains several active compounds, including berberine and hydrastine, which have been shown to help reduce inflammation and fight off bacterial and fungal infections. This makes goldenseal an effective treatment for a wide range of health issues, including digestive disorders, respiratory infections, and skin conditions.

Additionally, goldenseal is a natural detoxifier and can help to cleanse the liver and support healthy liver function. This is particularly beneficial for individuals who are looking to improve their overall health and wellbeing. Goldenseal can also help to support healthy immune function, making it an excellent choice for people who are looking to boost their immune system and reduce their risk of getting sick.

Choosing the Right Goldenseal Supplement

When it comes to choosing a goldenseal supplement, there are several things to consider. First and foremost, it's important to choose a high-quality supplement from a reputable manufacturer. Look for supplements that are made from organic goldenseal and that are standardized to contain a specific amount of the active compounds berberine and hydrastine. This will ensure that you are getting a consistent and effective dose of goldenseal with each serving.

It's also a good idea to choose a goldenseal supplement that is easy for your body to absorb. This can be achieved by choosing a supplement that is in a liquid or tincture form, as these are generally more easily absorbed by the body. Capsules and tablets can also be effective, but they may not be as easily absorbed as a liquid or tincture.

Final Thoughts

In conclusion, goldenseal is a powerful herbal supplement with numerous health benefits. Its anti-inflammatory and antimicrobial properties make it an effective treatment for a wide range of health issues, and its ability to support healthy liver function and immune function make it an excellent choice for anyone looking to improve their overall health and wellbeing. By choosing a high-quality goldenseal supplement from a reputable manufacturer and selecting a form that is easy for your body to absorb, you can ensure that you are getting the maximum benefit from this powerful herbal remedy.

Frequently Asked Questions (FAQs)

1. What is goldenseal supplement good for?

Goldenseal is commonly used as a dietary supplement for various conditions. It is believed to be beneficial for colds, respiratory tract infections, allergic rhinitis (hay fever), ulcers, and digestive issues like diarrhea and constipation.

2. Is it safe to take goldenseal everyday?

Goldenseal root should only be used for short periods of time. Typically, goldenseal root extract is taken in capsule or tablet form, in amounts of 4 to 6 grams three times per day. Using goldenseal powder as a tea or tincture may help soothe a sore throat.

3. What are the side effects of goldenseal supplements?

Goldenseal can cause various side effects, including digestive irritation and upset, contractions of the uterus, jaundice in newborns, and potential worsening of high blood pressure. Taking large amounts of goldenseal can have more severe effects, such as seizures and respiratory failure.

4. How does goldenseal help the immune system?

Goldenseal contains alkaloids like berberine and hydrastine, which are believed to support immune function. These compounds have antimicrobial properties, helping to fight bacteria and potentially slowing tumor growth.

5. Is goldenseal hard on the liver?

Studies suggest that goldenseal may reduce the activity of certain liver enzymes responsible for breaking down drugs. This may slow down the detoxification process instead of promoting it.

6. Who should not take goldenseal?

Pregnant or breastfeeding women should avoid using goldenseal. Additionally, individuals with high blood pressure, liver disease, or heart disease should consult their healthcare provider before taking goldenseal.

7. Does goldenseal fight inflammation?

Goldenseal is known for its antibacterial and anti-inflammatory properties. Although research on goldenseal is limited, it has the potential to help prevent respiratory infections and provide anti-inflammatory benefits.

Editor's Notes

During our goldenseal supplement research, we found 24 goldenseal supplement products and shortlisted 10 quality products. We collected and analyzed 59,674 customer reviews through our big data system to write the goldenseal supplements list. We found that most customers choose goldenseal supplements with an average price of $20.24.

The goldenseal supplements are available for purchase. We have researched hundreds of brands and picked the top brands of goldenseal supplements, including Integrative Therapeutics, Nature's Way, Nutricost, CEALMU CORE, Vimergy. The seller of top 1 product has received honest feedback from 48,371 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

Goldenseal Supplements Comparison Table

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#TOP10
Brand Integrative Therapeutics Integrative Therapeutics Nature's Way Nutricost CEALMU CORE Vimergy NOW Foods Carlyle Herb Pharm Wild & Organic
Item Form Capsule Capsule capsules Capsule Capsule drops Capsule Capsule Liquid Drop
Item Package Quantity 1 2 1 1 1 1 1 1 1 1
Package Information Bottle Pack Bottle Bottle Bottle Bottle Bottle Bottle Bottle Bottle
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.3
ftb score rating icon 9.2
ftb score rating icon 9.0
ftb score rating icon 8.8
ftb score rating icon 8.7
ftb score rating icon 8.6
ftb score rating icon 8.6
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