Best Hypoallergenic Face Serums of 2026

Aveeno Calm + Restore Triple Oat Hydrating Face Serum is formulated for sensitive and irritated, dry skin. The facial serum absorbs quickly, leaving skin feeling hydrated after just one use. The hypoallergenic formula, with Triple Oat Complex and calming feverfew, effectively calms irritated, dry skin while strengthening skin's moisture barrier for long-term resilience. The nourishing oat serum is fragrance-free, paraben-free, alcohol-free, dye-free, phthalate-free, tested on sensitive skin, and non-comedogenic. Dermatologist recommended for 3x the power of oat.

Honest Beauty Hyaluronic Acid Serum is a skin-quenching serum that draws and holds moisture in the skin to reduce fine lines. This facial serum is EWG Certified, hypoallergenic, and dermatologist tested. It is vegan and cruelty-free and does not contain parabens, phthalates, BHT, synthetic fragrances, or silicones. The serum is made with three types of hyaluronic acid, natural moisturizing factors, rambutan, and kiwi seed oil.

Cetaphil Renew Serum is a skincare product that can significantly improve your skin's firmness, texture, and tone in just 2 weeks. It boosts your skin's luminosity by hydrating it for 24 hours, revealing radiant and healthy-looking skin. This serum is a great alternative to retinol for those with sensitive skin as it contains purified peptides that provide anti-aging benefits without causing skin irritation or increasing sensitivity to the sun. Additionally, the formula respects your skin's natural moisture barrier, thanks to the hydrating and soothing properties of vitamins B3 and B5. With botanical extracts, it also targets visible dullness and uneven skin tone. The fast-absorbing formula is hypoallergenic, fragrance-free, and paraben-free, making it gentle enough for twice daily use. By using Cetaphil Renew Serum, you can defend against dryness, irritation, roughness, tightness, and a weakened skin barrier.

Cetaphil Ceramide Serum is designed to provide long-lasting hydration and improve your skin's overall health. With its clinically proven formula, it locks in moisture for up to 48 hours, helping to repair your skin's moisture barrier within just a week. You will notice a reduction in dryness and roughness while achieving a more even skin tone in just three days. Formulated with ceramides and Centella Asiatica, this lightweight serum strengthens your skin barrier and protects against environmental damage, making it perfect for even the most sensitive skin.

The Cetaphil Antioxidant-C Serum offers concentrated vitamin C to help protect your skin from dark spots and hyperpigmentation. Its unique GentleBright Complex, featuring 2% niacinamide, works to brighten your complexion and reduce the appearance of various skin imperfections, including age and post-acne marks. Designed for sensitive skin, this serum uses a gentle vitamin C derivative to enhance radiance without causing irritation. Additionally, it's hypoallergenic and oil-free, ensuring it won’t clog your pores. You can confidently use this effective serum day or night, knowing it addresses multiple signs of skin sensitivity.

The COSRX Snail Mucin 96% Power Repairing Essence is a lightweight, hydrating serum that is formulated with 96.3% Snail Secretion Filtrate. It absorbs quickly into the skin and provides long-lasting hydration without a heavy feeling. It is gentle enough for sensitive skin and helps to repair and rejuvenate the skin from dryness and aging. Customers have found this product to be incredibly effective in improving skin vitality, reducing dullness, and soothing dehydrated skin.

DearKlairs Serum is a daily serum that contains 5% pure Vitamin C and other natural ingredients to rejuvenate the skin. It helps with irritation, scars, breakouts, pore minimization, and pigmentation. The serum is safe and non-irritating, making it gentle enough for sensitive skin. With plentiful moisture and nutrition, it energizes and revitalizes your skin. DearKlairs Serum is a multi-functional serum that can fade brown spots and protect your skin from pigmentation. It comes in a 35ml bottle and is a genuine product from Wishtrend, the brand owner of Dear, Klairs.

Neutrogena Hydro Boost Hyaluronic Acid Serum is a daily facial serum that deeply quenches dry skin with a 17% Hydration Complex, delivering both high and low weight hyaluronic acid to instantly hydrate and leave skin feeling supple and refreshed. Suitable for all skin types, it is proven to smooth skin and hydrate for 24 hours, making it the perfect addition to your hydrating skincare routine.

The Cetaphil Vitamin C Serum offers a range of benefits designed to improve your skin's health and appearance. It provides 24-hour hydration, helping you maintain a well-moisturized complexion throughout the day. This serum also supports your skin’s natural moisture barrier, which is essential for keeping your skin protected and balanced. Additionally, it enhances your skin’s brightness, giving you a radiant and glowing look. With its ability to even out skin tone and texture, it helps reduce dark spots and fine lines, making your skin look smoother and more youthful. This lightweight formula is perfect if you have sensitive skin and want effective yet gentle care.

ZealSea 2% Pure Hyaluronic Acid Serum is a hydrating serum suitable for all skin types. With 2% concentration, it is deeply moisturizing but non-sticky after fully absorbed. The addition of Vitamin B5 promotes skin reproduction, enhances moisturizing ability, and protects from irritation. The serum comes in a unique blue transparent bottle design that is both young and unique. The product is cruelty-free, paraben-free, gluten-free, fragrance-free, and heavy metal-free. It is also suitable for men, girls, and boys. ZealSea offers a 90-day money-back refund for customer satisfaction.