Best Hypoallergenic Face Serums of 2025

Aveeno Calm + Restore Triple Oat Hydrating Face Serum is formulated for sensitive and irritated, dry skin. The facial serum absorbs quickly, leaving skin feeling hydrated after just one use. The hypoallergenic formula, with Triple Oat Complex and calming feverfew, effectively calms irritated, dry skin while strengthening skin's moisture barrier for long-term resilience. The nourishing oat serum is fragrance-free, paraben-free, alcohol-free, dye-free, phthalate-free, tested on sensitive skin, and non-comedogenic. Dermatologist recommended for 3x the power of oat.

The Cetaphil Antioxidant-C Serum offers concentrated vitamin C to help protect your skin from dark spots and hyperpigmentation. Its unique GentleBright Complex, featuring 2% niacinamide, works to brighten your complexion and reduce the appearance of various skin imperfections, including age and post-acne marks. Designed for sensitive skin, this serum uses a gentle vitamin C derivative to enhance radiance without causing irritation. Additionally, it's hypoallergenic and oil-free, ensuring it won’t clog your pores. You can confidently use this effective serum day or night, knowing it addresses multiple signs of skin sensitivity.

Cetaphil Renew Serum is a skincare product that can significantly improve your skin's firmness, texture, and tone in just 2 weeks. It boosts your skin's luminosity by hydrating it for 24 hours, revealing radiant and healthy-looking skin. This serum is a great alternative to retinol for those with sensitive skin as it contains purified peptides that provide anti-aging benefits without causing skin irritation or increasing sensitivity to the sun. Additionally, the formula respects your skin's natural moisture barrier, thanks to the hydrating and soothing properties of vitamins B3 and B5. With botanical extracts, it also targets visible dullness and uneven skin tone. The fast-absorbing formula is hypoallergenic, fragrance-free, and paraben-free, making it gentle enough for twice daily use. By using Cetaphil Renew Serum, you can defend against dryness, irritation, roughness, tightness, and a weakened skin barrier.

The COSRX Snail Mucin 96% Power Repairing Essence is a lightweight, hydrating serum that is formulated with 96.3% Snail Secretion Filtrate. It absorbs quickly into the skin and provides long-lasting hydration without a heavy feeling. It is gentle enough for sensitive skin and helps to repair and rejuvenate the skin from dryness and aging. Customers have found this product to be incredibly effective in improving skin vitality, reducing dullness, and soothing dehydrated skin.

Cetaphil Ceramide Serum is designed to provide long-lasting hydration and improve your skin's overall health. With its clinically proven formula, it locks in moisture for up to 48 hours, helping to repair your skin's moisture barrier within just a week. You will notice a reduction in dryness and roughness while achieving a more even skin tone in just three days. Formulated with ceramides and Centella Asiatica, this lightweight serum strengthens your skin barrier and protects against environmental damage, making it perfect for even the most sensitive skin.

DearKlairs Serum is a daily serum that contains 5% pure Vitamin C and other natural ingredients to rejuvenate the skin. It helps with irritation, scars, breakouts, pore minimization, and pigmentation. The serum is safe and non-irritating, making it gentle enough for sensitive skin. With plentiful moisture and nutrition, it energizes and revitalizes your skin. DearKlairs Serum is a multi-functional serum that can fade brown spots and protect your skin from pigmentation. It comes in a 35ml bottle and is a genuine product from Wishtrend, the brand owner of Dear, Klairs.

Honest Beauty Hyaluronic Acid Serum is a skin-quenching serum that draws and holds moisture in the skin to reduce fine lines. This facial serum is EWG Certified, hypoallergenic, and dermatologist tested. It is vegan and cruelty-free and does not contain parabens, phthalates, BHT, synthetic fragrances, or silicones. The serum is made with three types of hyaluronic acid, natural moisturizing factors, rambutan, and kiwi seed oil.

The Wellution Snail Serum is a powerful blend designed to hydrate and repair your skin. With 80% snail mucin, it rejuvenates and revitalizes dull skin, giving it a fresh appearance. This serum also contains hyaluronic acid and aloe vera, which deeply moisturize, leaving your skin feeling plump and radiant without being heavy. If you have sensitive or damaged skin, this formula soothes irritation and helps repair dryness caused by environmental factors. Plus, it's hypoallergenic and dermatologist-tested, making it safe for daily use on all skin types.

PF Rosé Serum is an oil-free, pearluminous formula enriched with Rose Water to tighten, brighten, soothe, and hydrate your skin. With antioxidant-rich Goji & Kakadu Plum, it helps maintain a radiant glow while preventing wrinkles. The product offers a full line of beauty products, ensuring hypoallergenic and safe options without harsh ingredients. It's a versatile solution for achieving healthy and glowing skin.

Aveeno Anti-Wrinkle Serum is designed for sensitive skin and helps reduce the appearance of fine lines and wrinkles. Its hydrating formula improves skin tone and texture, leaving your skin feeling smoother and healthier within just a week. The serum includes nourishing oat and niacinamide, which work together with cranberry extract, offering a gentle, plant-based alternative to retinol while providing antioxidant benefits. This hypoallergenic formula is safe for daily use and is free from harmful ingredients like fragrance and parabens, making it an ideal addition to your skincare routine.