Best Vertical Computer Mice of 2025

The Logitech Lift Vertical Ergonomic Mouse is a great fit for small to medium right hands, with a softly textured grip and snug thumb rest for level-above cosiness. It features easy-to-reach customisable buttons, whisper-quiet clicks and a SmartWheel for smooth, seamless scrolling. Connect via Bluetooth Low Energy or Logi Bolt USB to Windows, macOS, iPadOS, Chrome OS, or Linux, and enjoy up to 2 years battery life.

The Anker Wireless Vertical Ergonomic Optical Mouse is the perfect choice for those who spend long hours using a computer. Its ergonomic design encourages a healthy, neutral wrist and arm position, reducing overall strain. With 800/1200/1600 DPI resolution optical tracking technology, it provides precise tracking on a wide range of surfaces. The added next/previous buttons make web browsing more convenient. Additionally, it enters power-saving mode after 8 minutes idle, saving battery life. The package includes one Anker Wireless Vertical Ergonomic Optical Mouse, one 2.4G USB receiver, and one instruction manual.

The Logitech MX Vertical Wireless Mouse is designed with a unique 57-degree angle, placing your hand in a natural handshake position to reduce muscular strain by 10%. Its hyper-efficient 4000 DPI high-precision sensor provides precise tracking that requires 4x less hand movement compared to a traditional mouse with a 1000 DPI sensor. With cross-computer control, you can navigate seamlessly on three computers and copy-paste text, images, and files from one to the other using Logitech FLOW. The mouse can be connected via included wireless USB unifying receiver or Bluetooth smart technology or the included USB-C charging cable. The rechargeable battery lasts for 4 months on a full charge, and you can get 3 hours of use from a 1-minute quick charge.

The TECKNET Vertical Mouse offers seamless connectivity options, allowing you to switch between Bluetooth and 2.4GHz modes effortlessly. This means you can connect to multiple devices without sacrificing USB ports, making it perfect for modern laptops. With six adjustable DPI settings, you can customize sensitivity for different tasks, enhancing your workflow. The silent operation ensures you can work in quiet environments without disturbing others. Designed for ergonomics, this mouse promotes a natural wrist position, reducing strain during extended use, making it an ideal choice for anyone who spends long hours on the computer.

The Anker Ergonomic Optical USB Wired Vertical Mouse is designed with scientific ergonomic principles that encourage a healthy wrist and arm position, reducing overall strain. Its 1000/1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice. The added next/previous buttons offer convenience when webpage browsing, making it the superior choice for internet surfers, gamers, and people who work long hours at the computer. With a 1.5m/4.9ft USB cable length, the product is compact and easy to use.

The ProtoArc Bluetooth Mouse is designed with your comfort in mind. Its ergonomic shape includes an extended wrist rest, promoting a natural hand position that helps reduce fatigue during long hours of use. You can easily connect this mouse to up to three devices simultaneously, making it perfect for multitaskers. With adjustable DPI levels, you gain enhanced precision for various tasks, while the rechargeable battery ensures you won't run out of power unexpectedly. Enjoy a quieter workspace with its silent clicking feature, allowing you to focus without distractions.

The Perixx PERIMICE-713 is a wireless ergonomic vertical mouse designed for right-handed users suffering from RSI. Its natural vertical design promotes a comfortable posture, while the 6-button design offers increased productivity. The mouse is equipped with an optical sensor for accurate navigation and offers 3 adjustable DPI levels (800/1200/1600) for enhanced sensitivity. With a wireless range of up to 10 meters, the mouse has a power ON/OFF switch button and power-saving function. It also comes with a nano USB receiver, that can be stored in a compartment, and is compatible with Windows 7, 8, 10, 11 and later versions.

The Nulea Ergonomic Mouse is designed with advanced ergonomic features to provide a more comfortable and efficient user experience. Its 57 degree natural grip design keeps your forearm muscle in a natural position, reducing arm discomfort and relieving wrist pain. With 4 adjustable DPI levels, you can easily switch between different responsiveness settings depending on your needs, whether it's browsing the web or editing a diagram. The plug and play functionality makes it easy to set up, while the lightweight design improves posture and reduces pressure on your wrists and muscles. Additionally, the mouse features 11 RGB lighting options, allowing you to customize the underglow for a personalized working experience. Overall, the Nulea Ergonomic Mouse offers a comfortable grip, adjustable sensitivity, easy setup, and customizable lighting, making it a great choice for anyone in need of a reliable and ergonomic computer mouse.

The LEKVEY Ergonomic Vertical Wireless Mouse offers a sleek and rechargeable design that encourages healthy wrist and arm positions, reducing overall strain. The advanced functionality buttons provide convenience when browsing web pages, while the adjustable DPI levels allow for easy sensitivity adjustments. With a built-in rechargeable battery and easy-to-use nano USB receiver, this mouse is compatible with most Windows operating systems. Plus, LEKVEY offers great customer service with a 24-month warranty and lifetime technical support.

The TECKNET Vertical Mouse offers an ergonomic design that aligns with your hand's natural position, helping to reduce strain and discomfort during long working hours. With a rechargeable battery, you can enjoy up to three months of use on a single charge, eliminating the hassle of constantly replacing batteries. The mouse features a stable 2.4 GHz wireless connection, allowing you to work freely within a 10-meter range without interruptions. Additionally, its multifunction buttons enhance your browsing experience, making it easier to navigate web pages while keeping your workspace quiet and efficient.