Best Right-Handed Computer Mice of 2025

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Right-handed computer mice are designed to fit comfortably in the right hand, making them ideal for right-handed users. These mice come in a variety of shapes and sizes, with features such as customizable buttons, high precision sensors, and ergonomic designs that reduce strain on the hand and wrist. They are compatible with most operating systems and are suitable for a range of applications, from casual web browsing to professional gaming. With their intuitive design and advanced features, right-handed computer mice are a must-have accessory for anyone who spends a lot of time working on a computer.
At a Glance: Our Top Picks
Top 10 Right-Handed Computer Mice
HP Wireless Silent 280M Mouse
The HP Wireless Silent 280M Mouse is an ergonomically designed right-handed mouse that offers a reliable 2.4GHz wireless connection, up to 18 months of battery life, and up to 90% noise reduction on the left and right buttons. It is perfect for use in any space, and its HP Blue Optical Technology allows it to track on most surfaces without the need for a mouse pad.
Perixx PERIMICE-713 Wireless Vertical Mouse
The Perixx PERIMICE-713 is a wireless ergonomic vertical mouse designed for right-handed users suffering from RSI. Its natural vertical design promotes a comfortable posture, while the 6-button design offers increased productivity. The mouse is equipped with an optical sensor for accurate navigation and offers 3 adjustable DPI levels (800/1200/1600) for enhanced sensitivity. With a wireless range of up to 10 meters, the mouse has a power ON/OFF switch button and power-saving function. It also comes with a nano USB receiver, that can be stored in a compartment, and is compatible with Windows 7, 8, 10, 11 and later versions.
Logitech Lift Vertical Ergonomic Mouse
The Logitech Lift Vertical Ergonomic Mouse is a great fit for small to medium right hands, with a softly textured grip and snug thumb rest for level-above cosiness. It features easy-to-reach customisable buttons, whisper-quiet clicks and a SmartWheel for smooth, seamless scrolling. Connect via Bluetooth Low Energy or Logi Bolt USB to Windows, macOS, iPadOS, Chrome OS, or Linux, and enjoy up to 2 years battery life.
Logitech B100 Corded Mouse, Wired USB Mouse
The Logitech B100 Corded Mouse is a great choice for those looking for a comfortable, ambidextrous mouse that is easy to use and provides precise cursor control. It is a great choice for both right and left-handed users, and is perfect for everyday computer use. It is also compatible with Chromebooks, and requires no setup or additional software. Customers have praised the mouse for its accuracy, responsiveness, and affordability.
Perixx PERIMICE-513 Vertical Mouse
The Perixx Vertical Mouse is designed with your comfort in mind. Its ergonomic shape encourages a natural handshake position, helping to alleviate strain on your forearm during long computer sessions. You can easily adjust the tracking sensitivity with DPI settings of 1000 or 1600, allowing for precise control based on your needs. The mouse features a durable rubber-coated surface that ensures a firm grip, making it comfortable to use for extended periods. Plus, with a hassle-free plug-and-play setup and a long 5.9-foot cable, you can easily connect it to your computer without any additional drivers.
Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery
The Logitech M705 Marathon Wireless Mouse is a great choice for those looking for a reliable and comfortable mouse. It features a 3-year battery life, dual-mode scrolling, wireless freedom, 5 customizable buttons, and broad compatibility. However, the scroll wheel is too loose and the device switcher button is too close to the forward/backward buttons. Additionally, the Logitech Options software on MacOS can be buggy and unreliable.
Perixx PERIMICE-519 Wired Ergonomic Vertical Mouse
If you're looking for a comfortable and convenient mouse for long working hours, the Perixx Ergonomic Vertical Mouse is a great choice. Its vertical design promotes better positioning of the wrist and forearm, reducing strain and discomfort. The six-button layout includes a built-in DPI switch button, allowing you to easily switch between 800/1600 DPI. The side buttons are mapped as shortcuts for navigating forwards and backwards through your history. The advanced optical tracking sensor provides smooth and accurate tracking on any surface. Additionally, the mouse is silent-click, making it perfect for those who need a quiet working environment. The Perixx Ergonomic Vertical Mouse is compatible with Windows 7, 8, 10 and Mac operating systems, and is easy to install with its plug and play feature.
TECKNET Ergonomic Rechargeable Mouse
The TECKNET Vertical Mouse offers an ergonomic design that aligns with your hand's natural position, helping to reduce strain and discomfort during long working hours. With a rechargeable battery, you can enjoy up to three months of use on a single charge, eliminating the hassle of constantly replacing batteries. The mouse features a stable 2.4 GHz wireless connection, allowing you to work freely within a 10-meter range without interruptions. Additionally, its multifunction buttons enhance your browsing experience, making it easier to navigate web pages while keeping your workspace quiet and efficient.
Woddlffy Ergonomic Wireless Mouse with Adjustable DPI
The Woddlffy Ergonomic Mouse is a rechargeable, wireless vertical mouse designed for right-handed users. It features 6 buttons with adjustable 3 DPI levels (800/1200/1600 DPI) and is compatible with Windows, Linux, and Mac. The USB receiver is located at the bottom of the mouse for easy use. The ergonomic design promotes healthier hand posture, making it a more comfortable option for daily use.
Perixx PERIMICE-713W Wireless Mouse
The Perixx Wireless Ergonomic Mouse is designed with your comfort in mind, especially if you spend long hours at your computer. Its vertical design promotes a natural hand position, reducing strain and helping prevent repetitive strain injuries. You can easily adjust the mouse sensitivity with three DPI settings, allowing for precise navigation tailored to your needs. The wireless feature offers freedom of movement up to 10 meters away from your device, enhancing your workspace efficiency. Additionally, the built-in power switch helps conserve battery life, making it a practical choice for everyday use.
Frequently Asked Questions (FAQs)
1. Are all mice right-handed?
Not every mouse is specifically for lefties, many are ambidextrous in design so you can use them comfortably in either hand.
2. Are right-handed mice better than ambidextrous?
For more experienced players with an established grip style, ambidextrous mice better support fingertip or claw grips due to their lower-profile, neutral shape. Additionally, left-handed users gravitate to this shape due to the overall lack of premium gaming mice designed for lefties.
3. Is there a specific mouse for left-handed?
If you're looking for the best wireless left-handed mouse capable of offering incredible speed, precision, and performance, Razer has you covered. The Razer Viper Ultimate is one of the most popular mice in the world, with an incredible 70-hour battery life, and a range of 8 programmable buttons to choose from.
4. Why are there no left-handed gaming mice?
Most gaming mice are either made specifically to fit in the dominant right hand of the majority of users, or are designed to be as comfortable in either hand as possible. But, because of the smaller target audience, there are few that are made to cater for a purely left-handed ergonomic.
During our right-handed computer mice research, we found 24 right-handed computer mice products and shortlisted 10 quality products. We collected and analyzed 372,216 customer reviews through our big data system to write the right-handed computer mice list. We found that most customers choose right-handed computer mice with an average price of $21.67.
The right-handed computer mice are available for purchase. We have researched hundreds of brands and picked the top brands of right-handed computer mice, including HP, Perixx, Logitech, TECKNET, Woddlffy. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Mike Davis is a professionally trained electrician with six years of working experience in the electronics industry. He has written an array of web and mobile-based articles for e-magazines and blogs. He loves trying out some novel and popular gadgets and his expertise is in the areas of electronics and computers which is built over many years of working and personal experiences.