Best Thumb Button Computer Mice of 2026

Mike Davis Avatar
Mike Davis
Last Updated: Jan 13, 2026

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Thumb button computer mice are a popular choice for those who want a more efficient and comfortable way to navigate their computer. These mice have extra buttons located near the thumb area, allowing users to easily access frequently used functions without having to move their hand away from the mouse. This feature is particularly useful for gamers and graphic designers who need quick access to hotkeys. Thumb button computer mice come in a variety of designs, including wired and wireless options, and can be programmed to suit the user's needs. Overall, they offer a convenient and practical solution for those who spend a lot of time on their computer.

At a Glance: Our Top Picks

Logitech MX Master 4 Wireless Mouse Cover #TOP 1
Logitech MX Master 4 Wireless Mouse
ftb score rating icon 9.8
Logitech M705 Marathon Wireless Mouse Cover #TOP 2
Logitech M705 Marathon Wireless Mouse
ftb score rating icon 9.7
Logitech MX Master 4 for Mac Cover #TOP 3
Logitech MX Master 4 for Mac
ftb score rating icon 9.5

Top 5 Thumb Button Computer Mice

Logitech MX Master 4 Wireless Mouse

910-007558
Graphite
One Size
Logitech MX Master 4 Wireless Mouse Cover
Logitech MX Master 4, Ergonomic Wireless Mouse with Advanced Performance Haptic Feedback, Ultra-Fast Scrolling, USB-C Charging, Bluetooth, Windows, MacOS - Graphite

The Logitech MX Master 4 offers an advanced haptic feedback system that lets you feel precise responses when performing actions or using shortcuts, helping you stay productive. Its customizable Actions Ring places your most-used tools right at your cursor, making app navigation faster and more intuitive. The MagSpeed scroll wheel delivers ultra-fast scrolling at up to 1,000 lines per second, yet it can stop exactly where you want for precise control. With powerful connectivity options, including a USB-C dongle and Bluetooth, you can enjoy a strong, reliable wireless connection or flexible pairing across devices. This mouse is designed to boost your workflow efficiently and comfortably.

What We Like
Exceptional ergonomic design
Silent, soft mouse clicks
Customizable buttons and features
Excellent battery life
Multi-device connectivity

Logitech M705 Marathon Wireless Mouse

910-006033
Black
One Size
Logitech M705 Marathon Wireless Mouse Cover
Logitech M705 Marathon Wireless Mouse, Gaming Mouse Wireless, 2.4 GHz USB-A Receiver, 5-Programmable Buttons, 3-Year Battery, PC, Mac, Laptop, Chromebook - Black

The Logitech M705 Marathon Wireless Mouse is a great choice for those looking for a reliable and comfortable mouse. It features a 3-year battery life, dual-mode scrolling, wireless freedom, 5 customizable buttons, and broad compatibility. However, the scroll wheel is too loose and the device switcher button is too close to the forward/backward buttons. Additionally, the Logitech Options software on MacOS can be buggy and unreliable.

What We Like
3-year battery life
Dual-mode scrolling
Wireless freedom
5 customizable buttons
Broad compatibility

Logitech MX Master 4 for Mac

910-007575
Space Black
One Size
Logitech MX Master 4 for Mac Cover
Logitech MX Master 4 for Mac, Ergonomic Bluetooth Mouse with Advanced Performance Haptic Feedback, Ultra-Fast Scrolling, USB-C Charging, MacOS, iPadOS, Windows - Space Black

The Logitech MX Master 4 is designed specifically for Mac users, matching Apple’s finishes and offering seamless integration with macOS through Logi Options+. You’ll appreciate the USB-C charging feature that keeps your mouse powered without interrupting your work. This mouse also features a Haptic Sense Panel that provides customizable tactile feedback, helping you stay more productive by signaling specific actions and shortcuts. With the MagSpeed scroll wheel, you can scroll through long documents or web pages quickly and precisely, moving up to 1,000 lines per second while stopping exactly where you want. These features make the Logitech MX Master 4 a powerful and comfortable tool for your daily tasks.

What We Like
Mac-specific design
Customizable haptic feedback
Ultra-fast precise scrolling
USB-C charging support
#TOP 4

Logitech MX Ergo S Wireless Trackball Mouse

910-007259
Graphite
One Size
Logitech MX Ergo S Wireless Trackball Mouse Cover
Logitech MX Ergo S Advanced Wireless Trackball Mouse, USB-C Rechargeable Wireless Ergonomic Mouse with Bluetooth and Encrypted Dongle, 6 Programmable Buttons, for PC/Mac - Graphite

The Logitech MX Ergo S Mouse offers advanced thumb control, allowing you to switch easily between fast and precise cursor movements, making your work smoother and more accurate. Its 20-degree tilt design promotes better forearm posture, which helps reduce muscle strain, so you can stay comfortable during long hours of use. The mouse is shaped to fit medium to large hands with a soft rubber grip, providing ergonomic comfort that has been approved by experts. Plus, with six customizable buttons, you can tailor shortcuts and actions to your needs, improving your productivity and making everyday tasks quicker and easier.

What We Like
Advanced thumb control
Ergonomic 20-degree tilt
Comfortable contoured design
Six customizable buttons
#TOP 5

Logitech Wireless Mouse Signature M650 L Full Size

910-006265
Black
Logitech Wireless Mouse Signature M650 L Full Size Cover
Logitech Wireless Mouse Signature M650 L Full Size - Large Hands, 2-Year Battery, Silent Clicks, Customizable Buttons, Bluetooth, PC/Mac/Chromebook - Black, Right-Handed, Large

The Logitech Signature M650 L Full Size Wireless Mouse is designed for larger hands and provides long hours of comfort due to its contoured shape, soft thumb area, and rubber side grips. It is also incredibly quiet, allowing you to enjoy 90 percent less click noise with SilentTouch technology. It is compatible with Windows, macOS, Linux, Chrome OS, ipadOS, and Android operating systems and has a 24 month battery life.

What We Like
1) No interference between the old-type devices and this new one and it works well.
2) Incredibly quiet: there is virtually no sound whatsoever, none when you click or use the wheel.
3) Compatible with Windows, macOS, Linux, Chrome OS, ipadOS, and Android operating systems.
4) 24 month battery life.
5) Customizable side buttons with Logitech Options plus.
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is the thumb button on a mouse?

For mice with thumb buttons, these buttons can be programmed to perform any action. By default, these buttons move backward or forward in an Internet browser.

2. What are the 4 buttons in mouse?

All the functions of a Mac mouse are fairly similar to a Windows mouse in that they have a left button, a right button, and side button but they also include a the 360° scroll ball and the side buttons.

3. Why do gaming mice have extra buttons?

The side buttons on gaming mice are called programmable buttons. They are used to carry out in-game commands with the press of a button thus eliminating the need to use or memorize difficult hotkeys. Each button can be assigned or programmed to perform specific game actions.

Editor's Notes

During our thumb button computer mice research, we found 24 thumb button computer mice products and shortlisted 5 quality products. We collected and analyzed 213,792 customer reviews through our big data system to write the thumb button computer mice list. We found that most customers choose thumb button computer mice with an average price of $27.67.

The thumb button computer mice are available for purchase. We have researched hundreds of brands and picked the top brands of thumb button computer mice, including Logitech and more. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Mike Davis Avatar

Mike Davis is a professionally trained electrician with six years of working experience in the electronics industry. He has written an array of web and mobile-based articles for e-magazines and blogs. He loves trying out some novel and popular gadgets and his expertise is in the areas of electronics and computers which is built over many years of working and personal experiences.