Best Thumb Button Computer Mice of 2025

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Thumb button computer mice are a popular choice for those who want a more efficient and comfortable way to navigate their computer. These mice have extra buttons located near the thumb area, allowing users to easily access frequently used functions without having to move their hand away from the mouse. This feature is particularly useful for gamers and graphic designers who need quick access to hotkeys. Thumb button computer mice come in a variety of designs, including wired and wireless options, and can be programmed to suit the user's needs. Overall, they offer a convenient and practical solution for those who spend a lot of time on their computer.
At a Glance: Our Top Picks
Top 5 Thumb Button Computer Mice
Microsoft Ergonomic Mouse
The Microsoft Ergonomic Mouse is designed to reduce fatigue and injury while providing precise tracking on a variety of surfaces. It features two programmable buttons, optimized scrolling wheel, and a lightweight and durable design. Customers have praised its ergonomic design, precise tracking, and comfortable feel, though some have noted that it may not be suitable for multi-monitor setups.
J-Tech Digital Ergonomic Mouse
The J-Tech Digital Ergonomic Mouse V638 offers an ergonomic “handshake” design that reduces arm/wrist/hand strain, back/forward thumb buttons, a detachable non-skid anti-sweat palm rest that reduces drag, and adjustable responsiveness to 800, 1200, 1600 or 3200 DPI. It’s compatible with Windows 7/8/10, XP, Vista 7/8, Linux, Mac OS, etc., and includes a USB Nano Receiver/Dongle Transceiver that connects the ergonomic mouse wirelessly to the computer. The built-in lithium battery is fully rechargeable.
NYIEFADA Rechargeable Wireless Bluetooth Mouse
The NYIEFADA Bluetooth Mouse is a rechargeable wireless mouse that offers a range of convenient features. With its multi-process buttons, you can perform multiple actions with just one click, making it suitable for gaming. The ergonomic design of the mouse ensures a comfortable grip and reduces fatigue, while the anti-skid scroll wheel provides a smooth scrolling experience. The mouse supports connection with up to 3 devices via Bluetooth or USB receiver, making it compatible with various operating systems. With adjustable DPI sensitivity and multiple RGB lighting options, this mouse allows for personalized and precise control. With a working distance of up to 32FT, this mouse offers a powerful and stable connection. Overall, the NYIEFADA Bluetooth Mouse is a versatile and user-friendly option for PC gaming.
SANWA Bluetooth Trackball Mouse
The SANWA Trackball Mouse offers a comfortable ergonomic design that reduces wrist strain, making it ideal for long hours of use. With its silent clicking feature, you can work quietly in shared spaces without disturbing others. The adjustable DPI settings allow you to customize cursor speed for different tasks, ensuring precision whether you’re browsing or working on detailed projects. Plus, the ability to connect to two devices simultaneously enhances your productivity, letting you switch seamlessly between tasks without the hassle of plugging and unplugging. This mouse is perfect for anyone seeking comfort and efficiency.
INFINMIND Wireless Bluetooth Mouse
The INFINMIND Bluetooth Mouse is designed to enhance your computing experience. With its adjustable DPI settings, you can tailor the sensitivity to suit your daily tasks, whether you're working or browsing. The innovative Smart Flying Scroll feature enables you to navigate pages swiftly and quietly, making it perfect for a distraction-free environment. Its ergonomic design ensures comfort during long hours of use, reducing hand strain. Additionally, it supports connection with up to three devices, allowing you to switch seamlessly between them, which is great for multitasking across different platforms.
Frequently Asked Questions (FAQs)
1. What is the thumb button on a mouse?
For mice with thumb buttons, these buttons can be programmed to perform any action. By default, these buttons move backward or forward in an Internet browser.
2. What are the 4 buttons in mouse?
All the functions of a Mac mouse are fairly similar to a Windows mouse in that they have a left button, a right button, and side button but they also include a the 360° scroll ball and the side buttons.
3. Why do gaming mice have extra buttons?
The side buttons on gaming mice are called programmable buttons. They are used to carry out in-game commands with the press of a button thus eliminating the need to use or memorize difficult hotkeys. Each button can be assigned or programmed to perform specific game actions.
During our thumb button computer mice research, we found 24 thumb button computer mice products and shortlisted 5 quality products. We collected and analyzed 65,101 customer reviews through our big data system to write the thumb button computer mice list. We found that most customers choose thumb button computer mice with an average price of $18.73.
The thumb button computer mice are available for purchase. We have researched hundreds of brands and picked the top brands of thumb button computer mice, including Microsoft, J-Tech Digital, NYIEFADA, SANWA, INFINMIND. The seller of top 1 product has received honest feedback from 521 consumers with an average rating of 4.7.

Mike Davis is a professionally trained electrician with six years of working experience in the electronics industry. He has written an array of web and mobile-based articles for e-magazines and blogs. He loves trying out some novel and popular gadgets and his expertise is in the areas of electronics and computers which is built over many years of working and personal experiences.