Best Glycine Amino Acid Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 30, 2026

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Glycine amino acid supplements are becoming increasingly popular among health enthusiasts due to their numerous health benefits. Glycine is a non-essential amino acid that plays a crucial role in the body's production of proteins and enzymes. Supplementing with glycine has been shown to improve sleep quality, reduce inflammation, and enhance cognitive function. Additionally, glycine has been found to support the health of the digestive system and promote healthy skin. With its wide range of benefits, glycine amino acid supplements can be a valuable addition to a healthy lifestyle.

At a Glance: Our Top Picks

BULKSUPPLEMENTS.COM Glycine Powder Cover #TOP 1
BULKSUPPLEMENTS.COM Glycine Powder
ftb score rating icon 9.9
Thorne Glycine Amino Acid Support - 250 Capsules Cover #TOP 2
Thorne Glycine Amino Acid Support - 250 Capsules
ftb score rating icon 9.8
Clean Nutraceuticals CalmAgain Cover #TOP 3
Clean Nutraceuticals CalmAgain
ftb score rating icon 9.6

Top 4 Glycine Amino Acid Supplements

#TOP 1

BULKSUPPLEMENTS.COM Glycine Powder

GLY500
Multi
BULKSUPPLEMENTS.COM Glycine Powder Cover
BulkSupplements.com Glycine Powder - Glycine Supplements, Amino Acid Supplement - Unflavored & Gluten Free, 3g per Serving, 500g (1.1 lbs) (Pack of 1)

BULKSUPPLEMENTS.COM Glycine Powder is a pure and clean glycine supplement that supports the body, including liver and the immune system. It is unflavored, gluten-free, and contains no fillers or artificial flavors. With 1000mg per serving, it's a great addition to any shake, smoothie, and juice, or simply just water. All products are manufactured according to cGMP Standards to ensure the highest quality for manufacturing, packaging, labeling, and holding operations.

What We Like
Improved sleep quality
Natural sweet taste
Joint and inflammation support
No fillers or additives
Mixes easily in drinks
#TOP 2

Thorne Glycine Amino Acid Support - 250 Capsules

SA512
Thorne Glycine Amino Acid Support - 250 Capsules Cover
THORNE - Glycine - Amino Acid Support for Relaxation, Detoxification, and Muscle Function* - 250 Capsules

Thorne Glycine is an amino acid supplement that promotes relaxation, detoxification, and muscle function. It helps manage stress, aids in detoxifying the body, and modulates cytokine levels associated with obesity. This product is free from gluten, soy, dairy, shellfish, fish, and other major allergens. Trusted by healthcare professionals, families, and US National Teams, Thorne is committed to product integrity and science-backed formulas.

What We Like
Promotes relaxation for healthy stress management
Aids in detoxifying the body
Helps modulate cytokine levels in the body associated with obesity
Free from gluten, soy, dairy, shellfish, fish, and other major allergens
Trusted by healthcare professionals, families, and US National Teams
#TOP 3

Clean Nutraceuticals CalmAgain

5HTP
Natural
Clean Nutraceuticals CalmAgain Cover
Clean Nutraceuticals GABA 750mg 5 HTP 200mg L Tryptophan 500mg L Theanine 200mg Ashwagandha SAM-e L-Glycine - Mood Support Vitamins for Women and Men with L-Tyrosine 5-HTP (5-Hydroxytryptophan)

Clean Nutraceuticals CalmAgain is an advanced all-in-one supplement that combines GABA, L-Theanine, Ashwagandha, 5-HTP, L-Tryptophan, SAM-e, L-Glycine, Vitamin D3, Vitamin B6, Magnesium Glycinate, and L Tyrosine into one convenient solution. With larger dosages of GABA Powder (750mg), L-Theanine (200mg), and 5-HTP (200mg) than other supplements in the market, Clean CalmAgain is a powerful mood support and balance support complex. The product is perfect for those who are looking for a supplement that can help them manage stress, anxiety, and improve their overall mood. Clean CalmAgain is made with vetted and trusted ingredients and is proudly made in the USA in a registered and certified facility.

What We Like
Improved sleep quality
Enhanced focus and concentration
Calm and relaxation
No aftertaste or fillers
Comprehensive mood support
#TOP 4

Nutricost Glycine Powder 1lb

NTC420101
1 Pound (Pack of 1)
Nutricost Glycine Powder 1lb Cover
Nutricost Glycine Powder 1lb - Non-GMO, Gluten Free

The Nutricost Glycine Powder offers a full pound (16 ounces) of pure glycine, giving you plenty of supply to support your health needs. It comes with a handy scoop, making it easy to measure the right amount every time without guesswork. If you follow the suggested use, this container can last you about five months, which means fewer trips to restock. Plus, it’s made without genetically modified ingredients and is gluten-free, so you can feel confident about its quality and safety. The Nutricost Glycine Powder is designed to be a convenient and reliable choice for those seeking a clean supplement.

What We Like
Improved sleep quality
Sweet, pleasant taste
Easy to dissolve
Supports tendon and tissue health
Dependable product quality
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is amino acid glycine good for?

As an amino acid, glycine contributes to cellular growth and health. Glycine is one of the amino acids essential to the body's synthesis of the antioxidant glutathione. Cells produce glutathione in order to fight free radicals that can otherwise cause oxidative stress and damage cells, proteins, and DNA.

2. What is the supplement glycine used for?

Glycine is used for treating schizophrenia, stroke, benign prostatic hyperplasia (BPH), and some rare inherited metabolic disorders. It is also used to protect kidneys from the harmful side effects of certain drugs used after organ transplantation as well as the liver from harmful effects of alcohol.

3. Does glycine have side effects?

A few people have reported nausea, vomiting, and upset stomach after taking glycine. Such reports have been rare, and the symptoms have gone away after glycine was discontinued.

4. Does glycine actually work?

Studies show glycine can be effective in lowering blood sugar levels and increasing insulin production in healthy adults. In people with type 2 diabetes, studies have shown that glycine deficiencies can be improved by use of oral glycine.

Editor's Notes

During our glycine amino acid supplement research, we found 24 glycine amino acid supplement products and shortlisted 4 quality products. We collected and analyzed 84,331 customer reviews through our big data system to write the glycine amino acid supplements list. We found that most customers choose glycine amino acid supplements with an average price of $20.65.

The glycine amino acid supplements are available for purchase. We have researched hundreds of brands and picked the top brands of glycine amino acid supplements, including BulkSupplements, THORNE, Clean Nutraceuticals, Nutricost. The seller of top 1 product has received honest feedback from 6,276 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.