Best 5-HTP Amino Acid Supplements of 2025

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5-HTP amino acid supplements are a natural way to boost serotonin levels in the brain. Serotonin is a neurotransmitter that plays a role in mood regulation, sleep, and appetite. 5-HTP, or 5-hydroxytryptophan, is a precursor to serotonin and is derived from the amino acid tryptophan. 5-HTP supplements are often used to alleviate symptoms of depression, anxiety, and insomnia. They may also help with weight loss by reducing appetite and cravings. However, it is important to consult with a healthcare provider before taking 5-HTP supplements, especially if you are taking any medications or have a medical condition.
At a Glance: Our Top Picks
Top 10 5-HTP Amino Acid Supplements
NOW Supplements 5-HTP 100mg Veg Capsules
Improve your mood and relaxation with the NOW Supplements 5-HTP 100mg Veg Capsules, which are vegan and support the production of serotonin in the brain and central nervous system. These capsules can impact sleep, mood, appetite, and body temperature. The Griffonia Simplicifolia extract in these capsules helps to extract the intermediate metabolite between the amino acid L-tryptophan and serotonin. The product is GMP Quality Assured, non-GMO, and packaged in the USA by a family-owned company since 1968.
NOW 5-HTP 100mg
NOW 5-HTP is a vegan capsule that supports the production of serotonin in the brain and central nervous system, which can impact sleep, mood, appetite, and body temperature. It is typically used as a sleep supplement and supports positive mood and relaxation. With certifications such as dairy-free, egg-free, kosher, non-GMO, nut-free, soy-free, vegan/vegetarian, and GMP Quality Assured, you can trust the quality of the product. NOW 5-HTP is a great choice for those who want to improve their sleep quality and mood.
BulkSupplements 5-HTP 100mg Capsules
BulkSupplements 5-HTP Capsules are designed to enhance your overall health and well-being. These 100mg capsules provide essential nutrients that help you feel your best every day. They fit seamlessly into your busy lifestyle, making it easier to maintain your wellness goals whether you’re starting a health journey or are already health-conscious. For those constantly on the go, these compact capsules ensure you can keep up with your nutritional needs without hassle. Plus, you can trust that these supplements undergo rigorous testing, ensuring quality and transparency in every batch.
BulkSupplements 5-HTP 50mg Capsules
BulkSupplements 5-HTP Capsules are designed to enhance your overall health and well-being. These capsules provide essential nutrients that can help you feel your best every day. They are convenient for busy lifestyles, allowing you to maintain your wellness routine on the go. You’ll appreciate the transparency of this supplement, as it undergoes rigorous third-party testing to ensure quality. With a commitment to excellence, these capsules are produced in a facility that adheres to strict cGMP standards, ensuring you receive a consistent and reliable product every time.
BulkSupplements 5-HTP 200mg Capsules
BulkSupplements 5-HTP offers a convenient way to enhance your overall health. These 200mg capsules are designed to fit seamlessly into your busy lifestyle, making it easy to prioritize your well-being. Whether you're just starting your health journey or are already health-conscious, these capsules provide essential nutrients that support your wellness goals. Additionally, their compact size makes them perfect for on-the-go individuals, ensuring that you can maintain your health routine wherever life takes you. With a commitment to transparency and rigorous testing, you can feel confident in the quality of the product you choose.
Nutricost 5-HTP 200mg Capsules
Nutricost 5-HTP Capsules provide a convenient way to support your mood and overall well-being. Each capsule contains 200mg of high-quality 5-HTP, making it easy to incorporate into your daily routine. These capsules are vegetarian-friendly, ensuring that you can enjoy them regardless of your dietary preferences. Additionally, they are non-GMO and gluten-free, which means you can take them with confidence, knowing they align with your health goals. The product is also third-party tested by ISO-accredited laboratories, ensuring you receive a reliable supplement of the highest quality.
DR EMIL NUTRITION 200 MG 5-HTP Plus Formula
The DR EMIL NUTRITION 200 MG 5-HTP Plus Formula is a natural supplement that supports mood, stress, and sleep. This formula contains 200mg of pure 5-HTP supplemented with 20mg of SAMe and 20mg of L Tryptophan to optimize 5-HTP conversion and support stress levels in the body. It also contains vitamin B6 for improved 5-HTP conversion. Vitamin B6 has been shown to aid 5-HTP conversion, and this formula has enough to ensure efficacy. This product is vegan and promotes calm and relaxation, making it a natural way to support a calm and relaxed mood by supporting 5-HTP conversion in the body.
Organic 5-HTP Capsules with Vitamin B6 & Lions Mane
Triquetra Health’s Organic 5-HTP Capsules are a natural solution to promote a calm and relaxed mood, better quality sleep, and mental cognition. Derived from organic Griffonia Seeds and extracted using the purest water extraction method, this 5-HTP supplement has a 99% purity and concentration of 5-HTP, making it 10 times more potent than other leading 5-HTP products on Amazon. The formula is enhanced with vitamin B6 and organic Lions Mane, aiding in the 5-HTP to serotonin conversion process and cognition enhancement properties, respectively. Each serving of 2 capsules provides 200 mg of 5-HTP and 10 mg of Vitamin B6, clinically validated for effectiveness.
5HTP Liquid Drops for Mood, Sleep, and Relaxation
Double Wood's 5HTP Liquid Drops are a unique and effective serotonin supplement that is more absorbable than encapsulated 5 HTP products. With over 99% 5-HTP, Double Wood offers the first maximum absorption 5 HTP drops. This product may help support mood and nighttime relaxation. A bottle contains 60 servings of our 5 HTP supplement per bottle in a convenient dropped format, which is a two-month supply. The 5 HTP drops capsules are manufactured and tested in the USA, Gluten-Free, and Non-GMO.
NOW Supplements 5-HTP 100mg Chewables
NOW 5-HTP Chewables are a natural citrus flavored supplement that supports positive mood and neurotransmitter balance. Extracted from the seed of an African plant, this supplement is the intermediate metabolite between the amino acid tryptophan and serotonin. By supporting neurotransmitter balance, it can help improve your mood. The chewable form provides convenience and makes it easy to take on the go. Additionally, this supplement is Kosher and Non-GMO, ensuring that it meets certain dietary requirements. Lastly, the GMP Quality Assured certification means that every aspect of the NOW manufacturing process has been examined, ensuring that you are getting a high-quality product.
Frequently Asked Questions (FAQs)
1. Is 5-HTP an amino acid?
5-hydroxytryptophan (5-HTP) is a chemical that the body makes from tryptophan (an essential amino acid that you get from food).
2. Are 5-HTP supplements effective?
It found that supplementing with 5-HTP daily for six months prevented or significantly decreased the number of migraine attacks in 71% of participants ( 33 ). In another study in 48 students, 5-HTP produced a 70% decrease in headache frequency, compared to an 11% decrease in the placebo group ( 34 ).
3. Is there a downside to taking 5-HTP?
Too much 5-HTP in your body can cause a spike in serotonin levels, resulting in side effects such as: anxiety. shivering. serious heart problems.
4. Should you take 5-HTP everyday?
There is no specific recommended daily allowance for 5-HTP. Most people will take 50–100 mg per day after starting at a lower dose of 25 mg and increasing the dose weekly. A person should read their supplement label and talk to a doctor before taking any supplement.
During our 5-htp amino acid supplement research, we found 24 5-htp amino acid supplement products and shortlisted 10 quality products. We collected and analyzed 195,331 customer reviews through our big data system to write the 5-htp amino acid supplements list. We found that most customers choose 5-htp amino acid supplements with an average price of $17.14.
The 5-htp amino acid supplements are available for purchase. We have researched hundreds of brands and picked the top brands of 5-htp amino acid supplements, including NOW Foods, BulkSupplements, Nutricost, DR. EMIL NUTRITION, Triquetra Health. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

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