Best Allergy Medicine of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 14, 2025

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Allergy medicine is a type of medication that is designed to relieve the symptoms of allergies. These symptoms can include sneezing, runny nose, itchy and watery eyes, and even hives or rashes. There are a variety of allergy medicines available on the market, including antihistamines, decongestants, and nasal sprays. Antihistamines work by blocking the effects of histamine, which is the chemical responsible for causing allergy symptoms. Decongestants work by reducing the swelling in the nasal passages, while nasal sprays can provide relief for both nasal and eye symptoms. It's important to speak with a doctor or pharmacist before taking any allergy medicine, as some may have side effects or interact with other medications.

At a Glance: Our Top Picks

Amazon Basic Care Cetirizine Tablets Cover #TOP 1
Amazon Basic Care Cetirizine Tablets
ftb score rating icon 9.9
Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg Cover #TOP 2
Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg
ftb score rating icon 9.8
HealthA2Z Allergy Relief Cover #TOP 3
HealthA2Z Allergy Relief
ftb score rating icon 9.6

Top 10 Allergy Medicine

#TOP 1

Amazon Basic Care Cetirizine Tablets

Amazon Basic Care
SB-123
Amazon Basic Care Cetirizine Tablets Cover
Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 90 Count (Packaging may vary)

Amazon Cetirizine Allergy Relief offers effective 24-hour relief from allergy symptoms caused by both indoor and outdoor allergens. With cetirizine hydrochloride as the active ingredient, these tablets help alleviate annoying symptoms like a runny nose, sneezing, and itchy eyes. Whether you're dealing with pollen from flowers or dust from your home, these antihistamine tablets are designed to provide comfort. They are also gluten-free and are original prescription strength, ensuring that you receive the quality needed to manage your allergies effectively.

What We Like
Affordable pricing
Long-lasting effectiveness
Convenient bulk purchasing
Comparable to name brands
Helps with strong allergies
What We Don't Like
Space-consuming packaging
#TOP 2

Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg

Amazon Basic Care
400 Count
Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg Cover
Amazon Basic Care Complete Allergy Relief, Diphenhydramine HCl 25 mg, Relieves Symptoms, Antihistamine Tablets, 400 Count

Amazon Basic Care Allergy Relief provides multi-symptom relief for hay fever and upper respiratory allergies. Each tablet contains 25 mg of diphenhydramine HCl, an antihistamine, which can alleviate symptoms such as runny nose, sneezing, itching of the nose or throat, and itchy, watery eyes. The powerful dose of allergy-fighting medicine relieves allergy symptoms for 4-6 hours. These mini-tabs are easy to swallow, making them ideal for travel. Nighttime allergy relief is also available to help you rest. Suitable for adults and children 6 years and older.

What We Like
Effective as name brand
Cost-effective option
Easy to take
Large quantity for price
What We Don't Like
May cause drowsiness
#TOP 3

HealthA2Z Allergy Relief

HealthA2Z Allergy Relief Cover
HealthA2Z® Allergy Relief | Loratadine 10mg | Antihistamine | Non-Drowsy | Relief from Itchy Throat, Sneezing, Runny Noses | 24-Hours Allergy Medicine (300 Tablets)

HealthA2Z Allergy Medicine is a non-drowsy antihistamine that provides 24-hour relief from allergy symptoms. It is designed to alleviate sneezing, runny nose, itchy and watery eyes, as well as itchy nose or throat caused by allergens like pollen, dust mites, pet dander, and mold. With its active ingredient comparable to Claritin Tablets, HealthA2Z Allergy Medicine offers the same level of effectiveness at a more affordable price. Say goodbye to daytime sleepiness and enjoy uninterrupted allergy relief throughout the day. Suitable for adults and children 6 years and over, this allergy medicine is easy to take with just one tablet daily. For those with liver or kidney disease, it is recommended to consult a doctor.

What We Like
Affordable price
Effective allergy relief
Long-lasting 24-hour formula
Comparable to name brands
Convenient bulk quantity
What We Don't Like
None noted

TIME-CAP LABS, INC. Cetirizine HCl Allergy Relief Tablets

TIME-CAP LABS, INC. Cetirizine HCl Allergy Relief Tablets Cover
TIME-CAP LABS, INC. Timely Cetirizine HCl 10 Mg 365 Tablets - Compared to Zyrtec Active Ingredient Tablets – 24 Hour Allergy Relief from Sneezing, Runny Nose, Itchy Watery Eyes, Itchy Throat or Nose

Timely's Cetirizine HCl Allergy Relief Tablets are a fast and reliable non-drowsy medication that relieves sneezing, watery eyes, runny nose, itchy throat, hives, itches, and rashes on the skin. These easy-to-swallow tablets work within an hour of ingestion and provide 24 hours of allergy relief support. Timely's National Brand equivalency ensures effective allergy relief for less. Say goodbye to nagging discomfort and breathe the refreshing air with Timely's Cetirizine HCl 10 mg.

What We Like
Great price for quantity
Works as well as brand names
Quick delivery and service
Significant savings compared to others
Effective for allergy relief
What We Don't Like
Rectangular pill shape
Potential swallowing difficulty
#TOP 5

GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets

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GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets Cover
GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 365 Count

GoodSense All Day Allergy is an antihistamine tablet for indoor and outdoor allergy relief. It contains 10mg of cetirizine hydrochloride, which provides 24-hour relief from allergy symptoms such as runny nose, sneezing, itching, and watery eyes. GoodSense All Day Allergy is gluten-free and is comparable to Zyrtec. These allergy pills offer temporary relief from allergies that are caused by harmless substances such as flowers, trees, family pets, and dust.

What We Like
Effective allergy relief
Cost-effective option
Convenient one-a-day dosage
Large quantity available
Fast shipping
What We Don't Like
Price fluctuations noted
#TOP 6

Amazon Basic Care Loratadine 10 mg Tablets

Amazon Basic Care
10 mg, 90 Count
Amazon Basic Care Loratadine 10 mg Tablets Cover
Amazon Basic Care Allergy Relief Loratadine Tablets 10 mg, 90 Count (Packaging may vary)

Amazon Loratadine Allergy Relief offers effective relief from allergy symptoms with its active ingredient, Loratadine 10 mg. This powerful antihistamine works for a full 24 hours, helping you manage sneezing, runny nose, and itchy eyes without the drowsiness that comes with many allergy medications. Unlike some over-the-counter options, it provides prescription-strength relief without causing sleepiness, making it a great choice for daily use. Whether you suffer from hay fever or other respiratory allergies, this non-drowsy formula allows you to stay active and focused throughout the day.

What We Like
Affordable alternative to name brands
Effective allergy relief
HSA/FSA eligible
Large quantity for price
What We Don't Like
Not as effective as Zyrtec

GenCare Cetirizine HCL 10 mg

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GenCare Cetirizine HCL 10 mg Cover
GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec

GenCare Allergy Relief Pills provide effective 24-hour relief from allergies without causing drowsiness. You can tackle symptoms from indoor and outdoor allergens like pollen and pet dander, helping you feel comfortable throughout the day. The bulk packaging of 200 caplets ensures you always have allergy support available when you need it. If you experience mild symptoms, the option to break the pill into smaller doses offers added convenience. Plus, this powerful antihistamine quickly alleviates itchy eyes and congestion, so you can enjoy your day without interruption.

What We Like
Cost-effective alternative
Works as well as brand name
Quick shipping
Large quantity for price
#TOP 8

Claritin 24 Hour Allergy Medicine, 100 Count

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Claritin 24 Hour Allergy Medicine, 100 Count Cover
Claritin 24hr Non-Drowsy Allergy Relief, Loratadine Tablets - 100ct

Claritin 24 Hour Allergy Medicine provides a powerful, non-drowsy relief for indoor and outdoor allergies, including symptoms such as sneezing, runny nose, itchy/watery eyes, and itchy throat/nose. With 10mg of loratadine per tablet, it effectively blocks the effects of histamines from over 200 different allergens, including pets, pollen, dust, and mold. This #1 doctor recommended non-drowsy oral allergy brand does not require a prescription, making it easy to find relief.

What We Like
Effective for itching relief
Good price point
Reliable over years
Maintains effectiveness
What We Don't Like
Limited use duration
#TOP 9

Allegra 24HR Non-Drowsy Antihistamine, 70 Tablets

637764
70 Count
Allegra 24HR Non-Drowsy Antihistamine, 70 Tablets Cover
Allegra Adult 24HR Non-Drowsy Antihistamine, 70 Tablets, Fast-acting Allergy Symptom Relief, 180 mg

Allegra Adult 24HR Non-Drowsy Antihistamine provides fast-acting relief from allergy symptoms. With just one pill, you can get round-the-clock relief from sneezing, runny nose, itchy and watery eyes, and itchy nose or throat. The active ingredient fexofenadine is non-drowsy, making it perfect for indoor and outdoor allergies, including seasonal and pet allergies.

What We Like
Effective allergy relief
Non-drowsy formula
Convenient online reordering
Easy to swallow
Good price for quantity
What We Don't Like
May not work for everyone
On the pricier side

Zyrtec Allergy Relief Liquid Gels Capsules, 40 ct

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Zyrtec Allergy Relief Liquid Gels Capsules, 40 ct Cover
Zyrtec 24 Hour Allergy Relief Liquid Gels, Antihistamine Capsules with Cetirizine Hydrochloride Allergy Medicine for All-Day Relief from Runny Nose, Sneezing, Itchy Eyes & More, 40 ct

Zyrtec 24 HR Indoor/Outdoor Allergy Relief Liquid Gels Capsules contain cetirizine hydrochloride antihistamine allergy medicine that treats indoor and outdoor allergies caused by dust, mold, pet dander, tree pollen, weeds, and grasses. It starts working at hour one and works twice as hard when taken again the next day, providing all-day allergy relief. Suitable for adults and children six years and older, one dose of this anti-allergy medicine provides effective relief for 24 hours.

What We Like
Effective antihistamine
Fast-acting liquid form
Long-lasting relief
Gel caps easier to swallow
Reasonable price
What We Don't Like
Difficulty swallowing pills
Buying Guide Image

Allergy Medicine Buying Guide: What You Need to Know

Introduction

Allergies can be a pesky and uncomfortable annoyance for many people. Luckily, there are a wide variety of allergy medications available to help alleviate symptoms. However, with so many options on the market, it can be overwhelming to choose the right one. In this article, we'll discuss some factors to consider when selecting allergy medicine to help you find the best option for your needs.

Types of Allergy Medications

Before we dive into the specifics of choosing allergy medicine, it's important to understand the different types of allergy medications available.

Antihistamines

One of the most common types of allergy medications are antihistamines. These drugs work by blocking the effects of histamine, a chemical that is released by your body in response to an allergen. This can help to reduce symptoms such as sneezing, itching, and runny nose.

Decongestants

Another common type of allergy medication is decongestants. These drugs help to relieve nasal congestion by narrowing the blood vessels in the nose. This can help to reduce swelling and make it easier to breathe.

Corticosteroids

Corticosteroids are another type of allergy medication that can be effective in reducing symptoms. These drugs work by reducing inflammation in the body, which can help to alleviate symptoms such as congestion and swelling.

Immunotherapy

For people with severe allergies or allergies that are not well-controlled by other medications, immunotherapy may be an option. This type of treatment involves gradually exposing the body to increasing amounts of an allergen in order to build up immunity to it.

Factors to Consider

Now that we've covered the different types of allergy medications available, let's discuss some factors to consider when choosing the right allergy medicine for you.

Type and Severity of Allergies

One of the most important factors to consider when choosing allergy medicine is the type and severity of your allergies. For example, if you have seasonal allergies, an over-the-counter antihistamine may be sufficient to alleviate your symptoms. However, if you have more severe allergies or allergies that are not well-controlled by other medications, you may need a prescription medication or immunotherapy.

Possible Side Effects

Another factor to consider when choosing allergy medicine is the potential side effects. Some allergy medications may cause drowsiness, dry mouth, or other side effects, so it's important to read the label carefully and discuss potential side effects with your doctor.

Age and Other Medical Conditions

It's also important to consider your age and any other medical conditions you may have when choosing allergy medicine. For example, some allergy medications may not be suitable for children or people with certain medical conditions. Your doctor can help you to determine the best option for your needs.

Cost

Finally, it's important to consider the cost of allergy medication when choosing the right option for you. Some allergy medications may be more expensive than others, so it's important to weigh the cost against the potential benefits.

Conclusion

In conclusion, there are many factors to consider when choosing allergy medicine. It's important to consider the type and severity of your allergies, the potential side effects, your age and other medical conditions, and the cost of the medication. By taking these factors into account, you can find the right allergy medicine to help alleviate your symptoms and improve your quality of life.

Frequently Asked Questions (FAQs)

1. What medicine helps allergies fast?

When it comes to fast relief from allergies, antihistamines are commonly used. These medications work by blocking histamine, the chemical responsible for causing allergy symptoms like sneezing, itching, and runny nose. Some examples of antihistamines include cetirizine (Zyrtec Allergy), fexofenadine (Allegra Allergy), and loratadine (Claritin, Alavert).

2. Is it better to take Zyrtec at night or in the morning?

Cetirizine, also known as Zyrtec, can be taken at any time of the day. It is generally non-sedating for most people, so they prefer taking it in the morning. However, some individuals may experience drowsiness as a side effect. If cetirizine makes you drowsy, it is best to take it in the evening.

3. How do I stop allergies ASAP?

To get quick relief from allergies, antihistamines are effective in alleviating symptoms like sneezing, itching, a stuffy or runny nose, and watery eyes. Examples of oral antihistamines include cetirizine (Zyrtec Allergy), fexofenadine (Allegra Allergy), and loratadine (Claritin, Alavert). Additionally, corticosteroid nasal sprays can help improve nasal symptoms.

4. How do you get rid of allergies ASAP?

There are several ways to alleviate allergies quickly. These include using antihistamines, nasal steroid sprays, decongestants, and prescription allergy medications. Vitamin C can also help. Other measures include using humidifiers and dehumidifiers, switching to HEPA filters for heating and cooling systems, and considering the use of air purifiers.

Editor's Notes

During our allergy medicine research, we found 24 allergy medicine products and shortlisted 10 quality products. We collected and analyzed 917,064 customer reviews through our big data system to write the allergy medicine list. We found that most customers choose allergy medicine with an average price of $18.32.

The allergy medicine are available for purchase. We have researched hundreds of brands and picked the top brands of allergy medicine, including HealthA2Z, TIME-CAP LABS, INC., GoodSense, GenCare, Claritin. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.

Allergy Medicine Comparison Table

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Brand Amazon Basic Care Amazon Basic Care HealthA2Z TIME-CAP LABS, INC. GoodSense Amazon Basic Care GenCare Claritin Allegra Zyrtec
Product Benefits Allergy Control Allergy Control Allergy Control Allergy Control Allergy Control Allergy Control Allergy Control Allergy Control 24-HOUR RELIEF Over-the-counter antihistamine capsule
Item dimensions L x W x H 3.06 x 1.62 x 4.43 inches 1.87 x 1.87 x 3.94 inches 2 x 2 x 4 inches 2 x 2 x 3.5 inches 2.03 x 2 x 4.25 inches 2 x 1.75 x 3.5 inches - 3.76 x 1.55 x 3.08 inches 1.97 x 4 x 3.5 inches 6 x 5 x 4 inches
Special Feature Long-Lasting - Non Drowsy - Gluten Free Non Drowsy Non Drowsy Non-Drowsy Fast-Acting Fast-Acting
Item Weight 0.09 Pounds 0.19 Ounces 1.76 Ounces - 0.22 Pounds - - 0.01 Ounces 2.4 Ounces -
Specific Uses For Product - Allergy Relief, Fever, Runny Nose, Cold, Itchy Throat, itchy/watery eyes, sneezing, and itchy nose - Allergy, Runny Nose, Sneezing, Itchy Throat, Fever - Allergy Relief,Fever,Sneezing,Runny Nose,Itchy Throat,Itchy Eyes,Watery Eyes,Itchy Nose Allergy, Sneezing, Runny Nose, Itchy Throat - - Throat, Respiratory Allergies, Runny Nose, Sneezing, Itchy Eyes, Itchy Nose, Watery Eyes, Fever
FTB Score
ftb score rating icon 9.9
ftb score rating icon 9.8
ftb score rating icon 9.6
ftb score rating icon 9.5
ftb score rating icon 9.5
ftb score rating icon 9.4
ftb score rating icon 9.2
ftb score rating icon 9.0
ftb score rating icon 8.8
ftb score rating icon 8.8
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