Best Allergy Medicine for Antihistamine of 2026

Benadryl Ultratabs Allergy Relief Tablets are a doctor-recommended solution for allergy and cold symptoms. With 25mg diphenhydramine HCl per tablet, it provides powerful relief for sneezing, runny nose, itchy throat, and watery eyes due to upper respiratory allergies or the common cold. This 100-count bottle is easy to swallow for adults and children aged six and up, making it a convenient solution for indoor and outdoor allergies.

Amazon Basic Care Allergy Relief provides multi-symptom relief for hay fever and upper respiratory allergies. Each tablet contains 25 mg of diphenhydramine HCl, an antihistamine, which can alleviate symptoms such as runny nose, sneezing, itching of the nose or throat, and itchy, watery eyes. The powerful dose of allergy-fighting medicine relieves allergy symptoms for 4-6 hours. These mini-tabs are easy to swallow, making them ideal for travel. Nighttime allergy relief is also available to help you rest. Suitable for adults and children 6 years and older.

The Zyrtec Allergy Relief Tablets offer a convenient bundle with a 90-count bottle plus three single-dose travel packs, making it easy for you to manage allergies both at home and on the go. These tablets provide fast, 24-hour relief from common indoor and outdoor allergens like pollen, dust, and pet dander, starting to work within the first hour. They effectively reduce symptoms such as runny nose, sneezing, and itchy, watery eyes, helping you feel more comfortable throughout the day. Suitable for adults and children over six, this medication is designed for long-lasting relief from seasonal and year-round allergies.

ValuMeds 24-Hour Allergy Medicine provides fast and reliable support for allergy symptoms such as dry, itchy, watery eyes, a scratchy nose and throat, and sneezing. Its non-drowsy formula is safe for kids and adults, and a single dose can provide 24-hour relief. This medication starts working within an hour of ingestion and can be taken for indoor and outdoor protection.

Claritin 24 Hour Allergy Medicine provides a powerful, non-drowsy relief for indoor and outdoor allergies, including symptoms such as sneezing, runny nose, itchy/watery eyes, and itchy throat/nose. With 10mg of loratadine per tablet, it effectively blocks the effects of histamines from over 200 different allergens, including pets, pollen, dust, and mold. This #1 doctor recommended non-drowsy oral allergy brand does not require a prescription, making it easy to find relief.

Claritin Allergy Relief offers you effective, non-drowsy allergy relief that lasts all day with just one 10mg tablet. This product helps block histamines, which means it can ease common allergy symptoms like sneezing, runny nose, and itchy eyes, whether you’re indoors or outdoors. You don’t need a prescription to get relief from over 200 allergens, such as pollen, dust, and pet dander, making it convenient and accessible. Plus, the pack includes an extra travel-size tablet, so you can manage your allergies on the go without missing a beat.

Pataday Once Daily Relief Extra Strength Relief 2.5ml is a fast and effective antihistamine that relieves itchy eyes in minutes. It is easy to use with just one drop needed once a day, and provides relief for up to 24 hours. It contains the #1 doctor-prescribed eye allergy itch relief ingredient and works by limiting the release of chemicals that cause inflammation.

Amazon Basic Care Allergy Relief Tablets contain cetirizine hydrochloride, an antihistamine that provides 24-hour relief from common indoor and outdoor allergy symptoms, including runny nose, sneezing, itching, and watery eyes. These tablets are gluten-free and original prescription strength, approved for the treatment of both indoor and outdoor allergies. They are useful for those with sensitivities to harmless substances like flowers, trees, pets, and dust.

Get powerful relief for indoor and outdoor allergy symptoms with the Zyrtec 24 Hour Allergy Relief Tablets Bundle. This bundle includes one 30-count bottle and three 1-count travel packs of prescription-strength cetirizine allergy pills. Each tablet contains 10mg of cetirizine hydrochloride, providing all-day allergy relief that starts at hour one and works twice as hard when taken again the next day. Suitable for those 6 years and older, this medication effectively treats indoor allergies caused by dust, mold, and pet dander, as well as outdoor seasonal allergies caused by tree pollen, weeds, and grasses.

HealthA2Z Fexofenadine Hydrochloride 180mg is an antihistamine that provides 24-hour relief from indoor/outdoor allergies. It blocks the body's allergic responses and helps relieve hay fever or upper respiratory allergies such as runny nose, itchy/watery eyes, sneezing, and itchy nose and throat. Adults and children over 12 years old can take one 180 mg tablet with water once a day, while those under 12 years old should not use it. The product is suitable for those with kidney disease or over 65 years old, but they should consult a doctor first.