Best Alcohol Allergy Medicine of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 16, 2026

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Alcohol Allergy Medicine is a range of products designed to alleviate the symptoms of alcohol intolerance and allergy. These products are formulated with ingredients that help support the body's natural detoxification process and reduce inflammation caused by alcohol consumption. Some of the key ingredients found in these medicines include vitamins, minerals, and herbal extracts such as milk thistle, dandelion root, and turmeric. These products can help reduce symptoms such as headaches, nausea, and skin flushing, allowing individuals to enjoy alcohol in moderation without suffering from adverse reactions. It is important to note that these products are not a cure for alcohol allergy and should not be used to justify excessive drinking.

At a Glance: Our Top Picks

Zyrtec 24 Hour Children's Allergy Syrup Cover #TOP 1
Zyrtec 24 Hour Children's Allergy Syrup
ftb score rating icon 9.9
Amazon Basic Care Children's All Day Allergy Relief Cover #TOP 2
Amazon Basic Care Children's All Day Allergy Relief
ftb score rating icon 9.8
Astepro Azelastine HCI Nasal Spray Bundle Cover #TOP 3
Astepro Azelastine HCI Nasal Spray Bundle
ftb score rating icon 9.6

Top 10 Alcohol Allergy Medicine

Zyrtec 24 Hour Children's Allergy Syrup

00300450209146
Grape
8 Fl Oz (Pack of 1)
Zyrtec 24 Hour Children's Allergy Syrup Cover
Zyrtec Children’s 24-Hour Allergy Relief Syrup, 5 mg Cetirizine Hydrochloride Antihistamine, Kids Allergy Medicine for Indoor/Outdoor Allergies & Hay Fever, Dye-, Alcohol- & Sugar-Free, Grape, 8 fl oz

Zyrtec 24 Hour Children's Allergy Syrup provides relief from indoor and outdoor allergy symptoms, including runny nose, sneezing, itchy eyes, and itchy nose and throat. This allergy medicine contains 5mg of cetirizine hydrochloride per 5mL and is suitable for children over 2 years. It is both dye-free and sugar-free and comes in a kid-friendly grape flavor. The medicine effectively treats indoor allergies caused by dust, mold, and pet dander, as well as outdoor allergies caused by tree pollen, weeds, and grasses.

What We Like
Provides 24-hour relief from indoor and outdoor allergy symptoms
Comes in a kid-friendly grape flavor
Contains 5mg of cetirizine hydrochloride per 5mL
#TOP 2

Amazon Basic Care Children's All Day Allergy Relief

Amazon Basic Care
SB-123
Grape
8 Fl Oz (Pack of 1)
Amazon Basic Care Children's All Day Allergy Relief Cover
Amazon Basic Care 24 Hour Allergy Relief for Children, Cetirizine Hydrochloride Oral Solution 1 mg/mL, Grape Flavor, Dye Free, 8 fl oz (Pack of 1)

Amazon Basic Care Children’s All Day Allergy Relief provides 24-hour relief from runny nose, sneezing, itchy nose or throat, and itchy, watery eyes due to hay fever or other upper respiratory allergies. The grape-flavored syrup is specially formulated for kids aged 2 and older and is sugar-free, dye-free, alcohol-free, and gluten-free. One dose per day is enough to relieve the symptoms for a full day without affecting playtime. The active ingredient in this allergy medicine is cetirizine hydrochloride 5 mg/5 mL, which is an antihistamine that is comparable to the active ingredient in Children's Zyrtec.

What We Like
Provides 24-hour relief from allergy symptoms
Sugar-free, dye-free, alcohol-free, and gluten-free
Kid-friendly grape flavor that children will love

Astepro Azelastine HCI Nasal Spray Bundle

Clear
200 Count Bundle
Astepro Azelastine HCI Nasal Spray Bundle Cover
Astepro Nasal Spray and Tissue Bundle, 24-Hour Allergy Relief, Steroid-Free Azelastine HCI, Nasal Congestion, Runny & Itchy Nose, 200 Metered Sprays (Packaging May Vary)

The Astepro Allergy Nasal Spray offers fast relief by starting to work within just 30 minutes, so you won’t have to wait long to feel better. It provides up to 24 hours of comfort, helping to ease nasal congestion, runny nose, sneezing, and itchy nose throughout your day. This nasal spray is a full-strength allergy medicine, but you can get it without needing a prescription, making it easy to access when allergies strike. Plus, it works well for both indoor and outdoor allergies, giving you versatile relief no matter where you are.

What We Like
Fast-acting relief
All-day symptom control
Prescription strength
Non-prescription availability
Indoor and outdoor use
#TOP 4

Benadryl Children's Dye-Free Allergy Liquid, Bubble Gum, 4 fl. oz

493805
Clear
4 Fl Oz (Pack of 1)
Benadryl Children's Dye-Free Allergy Liquid, Bubble Gum, 4 fl. oz Cover
Children's Benadryl Dye-Free Allergy Relief Liquid + 12.5 mg Diphenhydramine HCl, Antihistamine Allergy Medicine for Kids Helps Relieve Runny Nose & Sneezing, Bubble Gum Flavor, 4 fl. oz

Benadryl Children's Dye-Free Allergy Liquid Medicine is a specially formulated antihistamine designed to temporarily relieve children's allergy symptoms caused by hay fever and other upper respiratory allergies. It contains diphenhydramine HCl that works to alleviate allergy symptoms including runny nose, sneezing, itching of nose or throat, and itchy, watery eyes. This allergy liquid medicine comes with a convenient dosing cup and a kid-friendly bubble gum flavor that your child will love.

What We Like
Convenient dosing cup
Kid-friendly bubble gum flavor
Alleviates allergy symptoms caused by hay fever and other upper respiratory allergies
#TOP 5

Benadryl Liquid Diphenhydramine Allergy Medicine

Benadryl Liquid Diphenhydramine Allergy Medicine Cover
Benadryl Allergy Medicine, Liquid Diphenhydramine HCl Antihistamines for Adults, Alcohol-Free, Hay Fever Allergy Relief for Sneezing, Runny Nose, Itchy & Watery Eyes, Wild Cherry 4 fl oz

Benadryl Allergy Liquid offers fast and effective relief from common allergy symptoms like sneezing, runny nose, itchy and watery eyes. Each dose contains diphenhydramine HCl, an antihistamine that starts working quickly to ease your discomfort. The wild cherry flavor makes the medicine pleasant to take, especially if you find other allergy meds hard to swallow. Plus, the clear dosing markings on the bottle help you measure the right amount easily, ensuring safe and accurate use. This alcohol-free liquid absorbs swiftly, so you can get back to feeling better without delay.

What We Like
Fast-acting relief
Alcohol-free formula
Easy-to-measure dosing
Family-friendly flavor
#TOP 6

Xyzal Children's Oral Solution for 24-Hour Allergy Relief

230200
5 Fl Oz
Xyzal Children's Oral Solution for 24-Hour Allergy Relief Cover
Xyzal Children's 24 Hour Allergy Relief Medicine for Kids, Levocetirizine Dihydrochloride Liquid Antihistamine, Bubble Gum, 5 Fl. oz.

Xyzal Children's Oral Solution delivers rapid relief from allergy symptoms, including sneezing, itchy, watery eyes, runny nose, and itchy nose and throat. It starts working in just one hour and provides all-night, all-day relief that is as effective at hour 24 as it is at hour 1. The product helps kids wake up feeling refreshed and comes in a great fruity flavor designed just for kids.

What We Like
Rapid relief from allergy symptoms
Provides 24-hour relief that is as effective at hour 24 as it is at hour 1
Helps kids wake up feeling refreshed
Comes in a great fruity flavor designed just for kids
#TOP 7

Amazon Basic Care Children's Allergy Relief Oral Solution

Amazon Basic Care
4 Fl Oz (Pack of 1)
Amazon Basic Care Children's Allergy Relief Oral Solution Cover
Amazon Basic Care Children's Allergy Relief Oral Solution, Diphenhydramine HCl, Cherry Flavor, 4 fl oz (Pack of 1)

Amazon Basic Care Allergy Relief is a children's allergy medicine that provides temporary relief for a variety of allergy symptoms. It contains Diphenhydramine HCl, an antihistamine, which helps to alleviate sneezing, runny nose, itching of the nose or throat, and itchy, watery eyes. With its cherry flavor, kids will love taking this medicine. It offers 4-6 hours of allergy relief per dose, allowing your child to feel better throughout the day. The medicine is gluten-free and alcohol-free, making it safe for kids aged 6-11. Amazon Basic Care Allergy Relief is a trusted option for parents looking for an effective and convenient solution to their child's allergy symptoms.

What We Like
Cherry flavor kids love
4-6 hours of relief
Gluten-free and alcohol-free
#TOP 8

Claritin Grape Flavored Kids Allergy Relief

81099
Grape
8 Fl Oz (Pack of 1)
Claritin Grape Flavored Kids Allergy Relief Cover
Claritin Children's Allergy Medicine, 24-Hour Non-Drowsy Loratadine 5mg, Antihistamine Liquid for Kids Aged 2 Years and Older, Grape Flavored, 8 fl oz.

Claritin Grape Flavored Kids Allergy Relief is a powerful and non-drowsy antihistamine that provides 24-hour relief from allergies for children. This kosher, dye-free, sugar-free and alcohol-free medicine inhibits the cascade triggered by allergies, and it can relieve symptoms caused by over 200 indoor and outdoor allergens. Each 5 mL teaspoon contains 5 mg of grape-flavored loratadine that has a kid-approved great taste. Children's Claritin is the #1 pediatrician recommended non-drowsy oral children's allergy brand, and 98% of parents are satisfied with Children's Claritin.

What We Like
Provides 24-hour relief from allergies for children
Inhibits the cascade triggered by allergies
Relieves symptoms caused by over 200 indoor and outdoor allergens
Kid-approved great taste
#TOP 9

Nasacort 24HR Allergy Nasal Spray for Adults

41167580059
Nasacort 24HR Allergy Nasal Spray for Adults Cover
Nasacort 24HR Allergy Nasal Spray for Adults, Non-drowsy & Alcohol Free, 120 Sprays, 0.57 fl. oz.

Nasacort 24HR Allergy Nasal Spray for Adults offers 24-hour relief from congestion, sneezing, and runny or itchy nose. Its nose-friendly formula has no scent or harsh taste, and it contains the #1 doctor recommended medicine for nasal allergy congestion. Its recyclable carton reduces plastic waste by 96k pounds, and the packaging may vary. It is non-drowsy and alcohol-free.

What We Like
Provides 24-hour relief from nasal allergy symptoms
Non-drowsy and alcohol-free formula
Contains the #1 doctor recommended medicine for nasal allergy congestion
Recyclable carton reduces plastic waste by 96k pounds
No scent or harsh taste
#TOP 10

Flonase Sensimist Allergy Relief Nasal Spray Multipack - 120 Sprays

353100267164
Flonase Sensimist Allergy Relief Nasal Spray Multipack - 120 Sprays Cover
Flonase Sensimist Allergy Relief Nasal Spray for Adults and Kids - 120 Sprays Total (2 Bottles of 60 Sprays Each)

Flonase Sensimist Allergy Relief Nasal Spray is a non-drowsy allergy medicine for kids and adults. The product includes two 60-spray bottles designed for kids and adults, respectively, with a gentle mist that is hardly noticeable. The nasal spray provides relief against nasal congestion, sneezing, itchy nose, itchy and watery eyes, and runny nose. There is no aftertaste, odor, or dripping. The formula is safe for children aged 2-11 and adults aged 12 and older.

What We Like
Non-drowsy
24-hour relief against multiple allergy symptoms
Gentle mist with no aftertaste, odor or dripping
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What allergy medicine can you take with alcohol?

Loratadine (Claritin), fexofenadine (Allegra), or cetirizine (Zyrtec) and alcohol are generally considered a slightly safer combination. These medications do not typically cause drowsiness or other side effects that are intensified by alcohol consumption.

2. How do you stop alcohol allergies?

The only way to avoid alcohol intolerance symptoms or an allergic reaction is to avoid alcohol or the particular beverage or ingredients that cause the problem. For a minor reaction, over-the-counter or prescription antihistamines might help reduce symptoms, such as itching or hives.

3. Why am I allergic to alcoholic drinks?

Alcohol intolerance occurs when your body doesn't have the proper enzymes to break down (metabolize) the toxins in alcohol. This is caused by inherited (genetic) traits most often found in Asians. Other ingredients commonly found in alcoholic beverages, especially in beer or wine, can cause intolerance reactions.

4. Do allergy pills work with alcohol?

Mixing alcohol with other cold or allergy medications, explains Ross, like Contac or Benadryl, can make driving or operating heavy machinery dangerous. "Nonsedating allergy medications like Claritin or Sudafed are safer to mix with alcohol," says Ross.

Editor's Notes

During our alcohol allergy medicine research, we found 24 alcohol allergy medicine products and shortlisted 10 quality products. We collected and analyzed 262,884 customer reviews through our big data system to write the alcohol allergy medicine list. We found that most customers choose alcohol allergy medicine with an average price of $12.40.

The alcohol allergy medicine are available for purchase. We have researched hundreds of brands and picked the top brands of alcohol allergy medicine, including Zyrtec, Astepro, Benadryl, Xyzal, Claritin. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.