Best Powder St. John's Wort Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 23, 2026

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Powder St. John's Wort Supplements are natural supplements made from the St. John's Wort plant. They are known for their ability to support emotional balance and promote a positive mood. These supplements contain hypericin and hyperforin, which are believed to increase the levels of serotonin and dopamine in the brain, helping to reduce anxiety and stress. Powder St. John's Wort Supplements are available in a powder form, making them easy to incorporate into various recipes, such as smoothies or baked goods. They are a great option for those looking for a natural way to support emotional health and well-being.

At a Glance: Our Top Picks

Joy-Filled Mood Support Supplement Cover #TOP 1
Joy-Filled Mood Support Supplement
ftb score rating icon 9.9
Clean Nutraceuticals St Johns Wort Rhodiola Rosea Ashwagandha Holy Basil Capsules Cover #TOP 2
Clean Nutraceuticals St Johns Wort Rhodiola Rosea Ashwagandha Holy Basil Capsules
ftb score rating icon 9.8
Zazzee Extra Strength St. John’s Wort 20:1 Extract Cover #TOP 3
Zazzee Extra Strength St. John’s Wort 20:1 Extract
ftb score rating icon 9.6

Top 6 Powder St. John's Wort Supplements

Joy-Filled Mood Support Supplement

Joy-Filled Mood Support Supplement Cover
Joy-Filled Mood Support Supplement - 7 Herb Complex w/St. Johns Wort | Stress Relief – Helps Calm The Mind & Body | 100% Plant-Based Happy Pills, Ashwagandha, Rhodiola Rosea | Adaptogens, 60 Ct

The Joy-Filled Mood Support Supplement is a 100% plant-based supplement designed to calm the mind and body, relieve stress, and boost mood. Formulated with 7 natural herbs such as Ginkgo Biloba, Rhodiola Rosea, and St. John's Wort, it helps you find inner joy and promotes an overall calming effect. It is vegan, non-GMO, and made with natural ingredients. It also comes with a 60-day return policy for customer satisfaction.

What We Like
Contains 7 natural herbs to promote relaxation and reduce stress
Vegan, non-GMO, and made with natural ingredients
Comes with a 60-day return policy for customer satisfaction
#TOP 2

Clean Nutraceuticals St Johns Wort Rhodiola Rosea Ashwagandha Holy Basil Capsules

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Clean Nutraceuticals St Johns Wort Rhodiola Rosea Ashwagandha Holy Basil Capsules Cover
Clean Nutraceuticals St Johns Wort Rhodiola Rosea Holy Basil Ashwagandha - Mood Support for Women and Men with Vitamin C & Black Pepper Extract - 90 Caps

Clean Nutraceuticals Mood Support Capsules is an advanced supplement that combines St. John's Wort, Rhodiola Herb, Ashwagandha, Holy Basil, Vitamin C, and Black Pepper Extract for mood support in women and men. The Positeava All In One Supplement provides 4 full-dose products in one support complex containing a full St Johns Wart, Rhodiola Rosea Supplement, Ashwagandha Pills, and Holy Basil Leaf. This powerful herbal complex supplement can be a convenient alternative to various supplements such as Ashwagandha Gummies, Rhodiola Tincture, St Johns Wort Oil, St Johns Wort Tincture, and Tulsi Capsules. With vetted and trusted ingredients, this all-in-one supplement is proudly made in the USA in a registered and certified facility. Experience the benefits of this mood support supplement that can help you maintain a positive mood, reduce stress, and support overall well-being.

What We Like
Improved focus and energy
Effective mood regulation
No noticeable side effects
Natural, clean ingredients
Easy to take by mouth
#TOP 3

Zazzee Extra Strength St. John’s Wort 20:1 Extract

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Zazzee Extra Strength St. John’s Wort 20:1 Extract Cover
Zazzee Extra Strength St. John’s Wort 20:1 Extract, 8000 mg Strength, 0.3% Hypericin, 150 Vegan Capsules, 5 Month Supply, Concentrated, Standardized 20X Extract, 100% Vegetarian, Non-GMO, All-Natural

Zazzee St. John’s Wort Extract offers exceptional value with 8000 mg strength per capsule and 150 capsules per bottle, providing a 5-month supply. The potent 20:1 extract with 0.3% Hypericin makes it one of the strongest dosages available. Hypericin, the beneficial compound, is standardized to a minimum of 0.3%, ensuring potent results. The product is natural, vegan, and non-GMO, free from harmful additives. Manufactured in the USA under stringent quality control, ensuring the best value for your health.

What We Like
Stress and anxiety relief
Improved mood
Better sleep quality
Natural herbal remedy
Long-lasting supply
#TOP 4

Toniiq St. John's Wort Capsules

Toniiq St. John's Wort Capsules Cover
Toniiq 1,000mg Ultra High Strength St. John's Wort Capsules (Non-GMO) - 7X Concentrated Extract - 0.3% Hypericin - Highly Purified and Bioavailable - 120 Capsules

Toniiq St. John's Wort Capsules contain 1,000mg of the highest quality St. John's wort powder in each serving, ethically sourced, grown and cultivated using an extraction process to ensure a 7:1 extract ratio. Each serving provides one of the highest concentrations of hypericin on the market, making this one of the most potent St. John's Wort supplements available. Produced in a GMP-certified and NSF-approved state-of-the-art manufacturing facility in the USA, each batch is tested for quality and purity both during and after manufacturing.

What We Like
High potency extract
Noticeable mood improvement
Stringent quality standards
Enhanced mental clarity
Supports restful sleep

AuraZen Mood Support Gummies by Clean Nutra

AuraZen Mood Support Gummies by Clean Nutra Cover
AuraZen Mood Support Saffron Gummies L-Theanine Ashwagandha Rhodiola St John's Wort Lions Mane GABA Vitamin D Magnesium Supplement | Calm Vegan Plant-Based Herbal Gummy by Clean Nutra

The Clean Nutra Mood Gummies are designed to support your emotional well-being and help you stay calm and focused. These gummies combine saffron, l-theanine, ashwagandha, rhodiola rosea, and magnesium to help regulate your mood and promote relaxation. With added vitamin D3, they support serotonin production, which can improve your overall mood. Instead of dealing with bitter powders or hard-to-swallow capsules, you get a tasty strawberry mandarin gummy that’s easy to take. Plus, ingredients like St. John’s Wort and lion’s mane work together to help your body handle stress and maintain a balanced, positive outlook throughout the day.

What We Like
Mood regulation blend
Supports emotional calm
Easy-to-take gummy form
Includes vitamin D3 for serotonin
Stress adaptation ingredients
#TOP 6

Healths Harmony St. John's Wort

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Healths Harmony St. John's Wort Cover
St John's Wort Capsules - Powerful & Potent Saint John's Wort Extract & Whole Herb Complex Standardized to 900mcg Hypericin for Balancing Daily Mood Support - Vegan Non-GMO & Lab Verified (120 Caps)

Healths Harmony St. John's Wort is a natural mood helper that provides 900mcg of Hypericin in every serving. It comes in 120 capsules per bottle, with each capsule containing 500mg of St. John's Wort extract. It is manufactured in a GMP-certified facility in the USA using globally sourced ingredients. Customers have reported feeling a sense of calm and reduced anxiety after taking this product, and it has helped some quit nicotine with fewer side effects than other medications.

What We Like
Improves mood stability
Reduces anxiety symptoms
Fast-acting results
Supports lifestyle changes
Good quality product
Buying Guide Image
Editor's Notes

During our powder st. john's wort supplement research, we found 24 powder st. john's wort supplement products and shortlisted 6 quality products. We collected and analyzed 154,599 customer reviews through our big data system to write the powder st. john's wort supplements list. We found that most customers choose powder st. john's wort supplements with an average price of $20.68.

The powder st. john's wort supplements are available for purchase. We have researched hundreds of brands and picked the top brands of powder st. john's wort supplements, including Happy Healthy Hippie, Clean Nutraceuticals, Zazzee, Toniiq, Healths Harmony. The seller of top 1 product has received honest feedback from 77 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.