Best Gluten-Free St. John's Wort Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 23, 2026

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Gluten-free St. John's Wort supplements are a great option for those looking to promote a healthy mood and reduce stress levels. These supplements are made from the flowering plant St. John's Wort, which has been used for centuries as a natural remedy for depression and anxiety. The gluten-free aspect makes them suitable for those with gluten sensitivities or celiac disease. These supplements are available in various forms such as capsules, tablets, and liquid extracts, making it easy to incorporate them into your daily routine. Always consult with a healthcare professional before starting any new supplements.

At a Glance: Our Top Picks

Nutricost St. John’s Wort Capsules (500mg) - Vegetarian and Non-GMO Cover #TOP 1
Nutricost St. John’s Wort Capsules (500mg) - Vegetarian and Non-GMO
ftb score rating icon 9.8
Nature's Way St. John's Wort Cover #TOP 2
Nature's Way St. John's Wort
ftb score rating icon 9.7
Horbäach St John's Wort 300mg Cover #TOP 3
Horbäach St John's Wort 300mg
ftb score rating icon 9.5

Top 10 Gluten-Free St. John's Wort Supplements

Nutricost St. John’s Wort Capsules (500mg) - Vegetarian and Non-GMO

NTC211101
Nutricost St. John’s Wort Capsules (500mg) - Vegetarian and Non-GMO Cover
Nutricost St John’s Wort Capsules (500mg) 120 Capsules - Vegetarian, Gluten Free and Non-GMO

Nutricost St. John’s Wort Capsules features 120 vegetarian capsules with 500mg of St. John's Wort per capsule. The product is non-GMO, gluten-free, soy-free, and vegetarian-friendly. Its only active ingredient is St. John's Wort, and it is made in a GMP compliant, FDA registered facility, which is third-party tested.

What We Like
Vegetarian-friendly
Non-GMO and gluten-free
Only active ingredient is St. John's Wort
#TOP 2

Nature's Way St. John's Wort

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Nature's Way St. John's Wort Cover
Nature's Way St. John's Wort Herb, Promotes a Positive Outlook*, 700 mg per 2-Capsule Serving, Non-GMO Project Verified, Vegan, 180 Capsules (Packaging May Vary)

Nature's Way Premium Herbal St. John’s Wort Herb is a supplement designed to help promote a positive outlook and support the body's ability to adapt to everyday stress. It is Non-GMO Project Verified, gluten-free, vegan, and free of salt, yeast-derived ingredients, wheat, soy, corn, dairy, or artificial colors, flavors, or preservatives. Adults take 2 capsules twice daily, and for best results, use for at least 2 months. Customer reviews suggest that it can help with mild to moderate depression, anxiety, and brain fog, although it is not FDA approved and should be discussed with a professional.

What We Like
Depression and mood support
Helps with anxiety and stress
Positive effect on energy
Affordable and cost-effective
Easy to take daily
#TOP 3

Horbäach St John's Wort 300mg

CL3698
Horbäach St John's Wort 300mg Cover
Horbäach St John's Wort Capsules 300mg | 120 Count | Non-GMO, Gluten Free | Herbal Extract

Horbäach St John's Wort offers a powerful 300 mg of this traditional herbal extract in easy-to-take capsules. This advanced formula is designed for quick release, making it convenient for you to incorporate into your daily routine. With a focus on purity and potency, this product ensures that you receive a high-quality supplement. Additionally, it is formulated without gluten, wheat, yeast, milk, and artificial additives, providing peace of mind for those with dietary restrictions. You can trust that you are choosing a product that is laboratory tested and backed by a commitment to superior quality.

What We Like
Effective for mood swings
Helps reduce anxiety
Easy-to-read information
Good alternative to prescriptions
Reputable brand
#TOP 4

Futurebiotics Chill Pill + Ashwagandha, Rhodiola, St. John’s Wort, & L-Theanine 2000 MG per Serving - Non-GMO, 120 Vegetarian Tablets

FB180-120
Futurebiotics Chill Pill + Ashwagandha, Rhodiola, St. John’s Wort, & L-Theanine 2000 MG per Serving - Non-GMO, 120 Vegetarian Tablets Cover
Futurebiotics Chill Pill + Ashwagandha, Rhodiola, St. John’s Wort, & L-Theanine - Non-GMO, 120 Vegetarian Tablets

Futurebiotics Chill Pill offers an advanced calming formula with Ashwagandha, Rhodiola Rosea, St. John's Wort, and L-Theanine for superior support. It is carefully manufactured in a cGMP Registered Facility in New York, ensuring purity and quality. The product is Vegan/Vegetarian friendly and free of GMOs, Gluten & Soy. Futurebiotics Chill Pill sources high-quality ingredients from around the world to provide you with the best. Experience premium ingredients working synergistically to help you relax and unwind.

What We Like
Noticeable mood improvement
Effective stress relief
Affordable price
Easy to swallow tablets
Supports better sleep
#TOP 5

Nature's Bounty St. John's Wort Capsules

Nature's Bounty St. John's Wort Capsules Cover
Nature's Bounty St. John’s Wort 300mg Capsules, Herbal Health Supplement, Promotes a Positive Mood, 100 Capsules

Looking for a quality St. John’s Wort supplement for mood support? Nature’s Bounty St. John’s Wort offers the mood support you need to feel calm, relaxed and ready to take on life’s challenges. Trusted for centuries as a tonic and popularly used to promote mental well-being, St. John’s Wort at a daily dose of 900 mg per day can help you maintain a positive mood and healthy emotional outlook. Simply take three capsules of Nature’s Bounty St. John’s Wort per day. Capsules may also be opened and prepared as a soothing tea. Each pack contains 100 capsules.

What We Like
No major side effects
Mood stabilization
Natural herbal remedy
Improved stress management
Affordable pricing
#TOP 6

Horbaach St. John's Wort Tincture

CL39699
2 Fl Oz (Pack of 1)
Horbaach St. John's Wort Tincture Cover
Horbäach St Johns Wort Tincture | 2 Fl Oz | Alcohol Free | Vegetarian Liquid Extract | Non-GMO, Gluten Free Supplement

Horbaach St. John's Wort is a vegetarian, non-GMO, and gluten-free liquid extract that comes in a 2 fl oz bottle. It is expertly crafted to provide a super-concentrated alcohol-free liquid extract of St. John's Wort, a yellow flower with antioxidant flavonoids. Horbaach St. John's Wort is laboratory tested and made with trusted ingredients, ensuring superior quality. Its formula is backed by the brand's commitment to purity and potency. With this product, you can experience the benefits of St. John's Wort in a convenient and easy-to-use liquid form. It is perfect for those who prefer liquid supplements over pills or tablets. This tincture can help support a healthy mood and emotional balance, making it a great addition to your daily routine.

What We Like
Alcohol-free
Vegetarian formula
Non-GMO
#TOP 7

Zazzee Extra Strength St. John’s Wort 20:1 Extract

StJohnsWort150
Zazzee Extra Strength St. John’s Wort 20:1 Extract Cover
Zazzee Extra Strength St. John’s Wort 20:1 Extract, 8000 mg Strength, 0.3% Hypericin, 150 Vegan Capsules, 5 Month Supply, Concentrated, Standardized 20X Extract, 100% Vegetarian, Non-GMO, All-Natural

Zazzee St. John’s Wort Extract offers exceptional value with 8000 mg strength per capsule and 150 capsules per bottle, providing a 5-month supply. The potent 20:1 extract with 0.3% Hypericin makes it one of the strongest dosages available. Hypericin, the beneficial compound, is standardized to a minimum of 0.3%, ensuring potent results. The product is natural, vegan, and non-GMO, free from harmful additives. Manufactured in the USA under stringent quality control, ensuring the best value for your health.

What We Like
Stress and anxiety relief
Improved mood
Better sleep quality
Natural herbal remedy
Long-lasting supply
#TOP 8

NOW Supplements Mood Support

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NOW Supplements Mood Support Cover
NOW Supplements, Mood Support with St. John's Wort, Nutrient and Herbal Extracts, 90 Veg Capsules

NOW Supplements Mood Support is a nutritional supplement with both nutrients and herbal extracts that aid in the support of a healthy nervous system and a positive, balanced mood state*. It includes 450 mg St. John's Wort Extract, 100 mg Holy Basil Extract, 50 mg Valerian and more per serving. It is Soy Free, Non-GMO, Vegan, Nut Free, Made without Gluten, Dairy Free, Egg Free and GMP Quality Assured. Customers have reported feeling calmer, more balanced, and in control of their emotions after taking this supplement.

What We Like
GMP Quality Assured
Vegan, Non-GMO, Soy Free, Nut Free, Gluten Free, Dairy Free, Egg Free
Customers report feeling calmer, more balanced, and in control of their emotions
#TOP 9

NOW Supplements St. John's Wort

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NOW Supplements St. John's Wort Cover
NOW Foods Supplements, St. John's Wort (Hypericum perforatum) 300 mg, Standardized Extract, 250 Veg Capsules

NOW Supplements St. John's Wort (Hypericum perforatum) is a standardized extract of 300 mg in vegan capsules. It has a long history of traditional use by herbalists dating back more than 2000 years. It is Non-GMO Project Verified, Kosher, Soy Free, Vegan/Vegetarian, Nut Free, Made without Gluten, Dairy Free, and Egg Free. Customers have reported it to be helpful with mood and depression, mental clarity, and hormone balance. It is recommended to take 1 capsule 3 times daily, preferably with food.

What We Like
Increased motivation and energy
Improved mood and mental clarity
Effective for depression symptoms
Affordable larger bottle option
Natural alternative to medications
#TOP 10

Carlyle St John's Wort Capsules

CL3697
Carlyle St John's Wort Capsules Cover
Carlyle St John's Wort Capsules | 4800mg | 300 Count | Non-GMO & Gluten Free Supplement | Standardized Extract

Carlyle St John's Wort Capsules are a non-GMO and gluten-free supplement that provides the equivalent of 4800mg of St. John's Wort per serving through a standardized extract. The supplement is naturally free of gluten, wheat, yeast, milk, lactose, artificial flavor, and sweetener. The yellow flower with naturally occurring antioxidant flavonoids helps you pursue healthy living through Carlyle's premium and honest supplements. The laboratory-tested, trusted ingredients assure superior quality, and the product comes with a 100% guarantee.

What We Like
Provides the equivalent of 4800mg of St. John's Wort per serving through a standardized extract.
Naturally free of gluten, wheat, yeast, milk, lactose, artificial flavor, and sweetener.
The yellow flower with naturally occurring antioxidant flavonoids helps you pursue healthy living.
Buying Guide Image
Editor's Notes

During our gluten-free st. john's wort supplement research, we found 24 gluten-free st. john's wort supplement products and shortlisted 10 quality products. We collected and analyzed 97,987 customer reviews through our big data system to write the gluten-free st. john's wort supplements list. We found that most customers choose gluten-free st. john's wort supplements with an average price of $16.10.

The gluten-free st. john's wort supplements are available for purchase. We have researched hundreds of brands and picked the top brands of gluten-free st. john's wort supplements, including Nutricost, Nature's Way, Futurebiotics, Nature's Bounty, Zazzee. The seller of top 1 product has received honest feedback from 33,380 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.