Best Powder MSM Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 3, 2025

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Powder MSM supplements offer a natural and effective way to support overall joint health and reduce inflammation. This high-quality powdered supplement contains methylsulfonylmethane (MSM), a sulfur compound that plays a crucial role in maintaining healthy connective tissues. With its fine texture, the powder can be easily mixed into beverages or added to smoothies, making it convenient to incorporate into daily routines. Powder MSM supplements are a popular choice among individuals looking for a reliable and affordable option to support joint mobility and promote overall wellness.

At a Glance: Our Top Picks

Doctor's Best MSM Powder with OptiMSM Cover #TOP 1
Doctor's Best MSM Powder with OptiMSM
ftb score rating icon 9.8
BULKSUPPLEMENTS.COM MSM Powder - Methylsulfonylmethane Supplement Cover #TOP 2
BULKSUPPLEMENTS.COM MSM Powder - Methylsulfonylmethane Supplement
ftb score rating icon 9.7
Nutricost MSM Powder Cover #TOP 3
Nutricost MSM Powder
ftb score rating icon 9.5

Top 10 Powder MSM Supplements

Doctor's Best MSM Powder with OptiMSM

DRB-00076
Doctor's Best MSM Powder with OptiMSM Cover
Doctor's Best MSM Powder with OptiMSM, Non-GMO, Vegan, Gluten Free, Soy Free, 250g

Doctor's Best MSM Powder with OptiMSM is a natural sulfur compound that helps support the formation of healthy connective tissues. It also helps support overall joint mobility, reduces joint pain, and increases range of motion. MSM provides support for immune function, and for the body's antioxidant and overall protective capacities resulting in a stronger immune response. It also restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails. With numerous clinical studies, MSM can help support healthy skin, joint mobility, cartilage, and the antioxidant response.

What We Like
Non-GMO, Vegan, Gluten Free, Soy Free
Provides support for immune function
Restores collagen production that supports healthy skin
Helps support overall joint mobility, reduces joint pain, and increases range of motion
Backed by numerous clinical studies for safety and efficacy

BULKSUPPLEMENTS.COM MSM Powder - Methylsulfonylmethane Supplement

BULKSUPPLEMENTS.COM MSM Powder - Methylsulfonylmethane Supplement Cover
BulkSupplements.com MSM Powder - Methylsulfonylmethane, MSM Supplement - MSM Pure Powder, MSM 3000mg - for Joint Health, Gluten Free, 3000mg per Serving, 1kg (2.2 lbs) (Pack of 1)

BULKSUPPLEMENTS.COM MSM Powder is a dietary supplement that helps support joint health, immune system, and overall wellness. It is gluten-free, filler-free, and easy to add to any beverage. With 3000mg of MSM pure powder per serving, this MSM supplement is made according to cGMP standards to ensure the highest quality.

What We Like
Easy to add to any beverage
Gluten-free and filler-free
Supports joint health and immune system
3000mg of MSM pure powder per serving
Manufactured according to cGMP standards
#TOP 3

Nutricost MSM Powder

NTC048101
Nutricost MSM Powder Cover
Nutricost Pure MSM Powder 500 Grams (Methylsulfonylmethane)

Nutricost MSM Powder is a high-quality supplement that provides 1 gram of MSM powder per serving. With 500 servings per bottle, this product offers great value for money. MSM, or Methylsulfonylmethane, is known for its potential benefits in supporting joint health and reducing inflammation. This gluten-free and non-GMO formula is manufactured in a GMP compliant, FDA registered facility, ensuring its quality and safety. Nutricost MSM Powder is an excellent choice for those looking to support their joint health and overall well-being.

What We Like
High-quality MSM powder
500 servings per bottle
Gluten-free and non-GMO
#TOP 4

NOW Supplements MSM Powder for Joint Health, 1lb

2126
White
NOW Supplements MSM Powder for Joint Health, 1lb Cover
NOW Foods Supplements, MSM (Methylsulfonylmethane) Powder, Supports Healthy Cartilage*, Joint Health*, 1-Pound

Support your joint health with NOW Supplements MSM Powder. MSM helps create chemical links needed to form and maintain structural tissues, including cartilage and skin. This product is non-GMO, dairy-free, egg-free, gluten-free, soy-free, kosher, vegan, vegetarian, sugar-free, and nut-free. It is packaged in the USA by a family-owned company and has undergone NPA A-rated GMP certification. Be mindful of exposure to heat or sunlight, which may cause the product to melt or become damaged.

What We Like
Supports healthy cartilage and joint health
Non-GMO, dairy-free, egg-free, gluten-free, soy-free, kosher, vegan, vegetarian, sugar-free, and nut-free
Undergone NPA A-rated GMP certification
#TOP 5

Pure Organic Ingredients MSM Powder - Natural Sulfur Dietary Supplement

Pure Organic Ingredients MSM Powder - Natural Sulfur Dietary Supplement Cover
Methylsulfonylmethane MSM Powder (2 lbs), Always Pure, Natural Sulfur Dietary Supplement

This Pure Organic Ingredients MSM Powder is a natural sulfur dietary supplement made from a single ingredient without any fillers or additives. MSM is a natural source of bioavailable sulfur which is found naturally in some green vegetables and in the human body. This supplement provides digestive health support and helps maintain connective tissue health as well as respiratory and digestive support. The powder is packaged in Utah, USA, and comes in a 32-ounce bag.

What We Like
Pure and undiluted supplement
Natural source of bioavailable sulfur
Provides digestive health support
Maintains connective tissue health
Free from fillers, additives, and preservatives

Kala Health MSMPure Fine Powder, 8.8 oz

0320030
Kala Health MSMPure Fine Powder, 8.8 oz Cover
KALA HEALTH MSMPure Fine MSM Powder Crystals – Organic Sulfur for Joint Flexibility, Skin Appearance, and Hair & Nail Support – 8.8 oz, USA Made, Distilled Flakes

Kala Health MSMPure Fine Powder is a 99% pure distilled MSM supplement made in the USA. It is the only GRAS-designated, Kosher & Halal certified, non-GMO, gluten-free, allergen-free, non-shellfish-derived, vegan MSM backed by extensive toxicology data. MSMPure improves joint function and mobility, reduces joint pain and stiffness, aids in short term recovery, promotes nail and hair growth, improves skin texture and reduces fine lines and wrinkles. It has immune support and protects cartilage. Kala Health offers a No-Risk 100% Satisfaction Guarantee.

What We Like
99% pure distilled MSM supplement
GRAS-designated, Kosher & Halal certified, non-GMO, gluten-free, allergen-free, non-shellfish-derived, vegan MSM backed by extensive toxicology data
Improves joint function and mobility, reduces joint pain and stiffness, aids in short term recovery, promotes nail and hair growth, and improves skin texture and reduces fine lines and wrinkles
#TOP 7

Jarrow Formulas MSM - 2.2 lbs Powder

MSMKILO
Jarrow Formulas MSM - 2.2 lbs Powder Cover
Jarrow Formulas MSM Powder, Methylsulfonylmethane, 1,000mg, Antioxidant Mineral, Joint Health Supplement and Skin Support, 2.2 lbs, Approx. 1000 Servings

Jarrow Formulas MSM powder is a dietary supplement that supports joint health and connective tissues. MSM is a source of sulfur, which is an antioxidant mineral found in the body's structural proteins. This product is informed by strong scientific research and offers superior formulas.

What We Like
Supports joint and connective tissue health
Source of sulfur, an antioxidant mineral
Informed by strong scientific research
#TOP 8

Emerald Labs MSM Powder Supplement

ub10127
8 Ounce (Pack of 1)
Emerald Labs MSM Powder Supplement Cover
Emerald Labs MSM Powder - Plant-Sourced Methylsulfonylmethane Supplement for Liver Detox, Joint Health, Skin Health & More - Vegan, Gluten-Free - 8 oz

Emerald Labs MSM Powder is a powerful supplement that provides 4000mg of methylsulfonylmethane (MSM) per serving, promoting optimal joint support. This supplement also aids in keratin production, which can enhance your skin, hair, and nails, contributing to overall wellness. In addition, it supports the production of glutathione, a key antioxidant that boosts your immune health. Being vegan and gluten-free, this MSM Powder caters to various dietary needs, making it a convenient choice for those looking to improve their health without additives.

What We Like
High MSM dosage
Supports skin and hair health
Boosts immune system
Vegan and gluten-free

Pure Encapsulations MSM Powder

MSMP
8 Ounce (Pack of 1)
Pure Encapsulations MSM Powder Cover
Pure Encapsulations MSM Powder | Hypoallergenic Supplement Supports Joint, Immune, and Respiratory Health | 8 Ounces

Pure Encapsulations MSM Powder is a hypoallergenic supplement designed to provide support for joint, immune and respiratory health. It contains MSM, which is a naturally-derived sulfur formula that helps support joint functionality, immune and respiratory health, as well as hair, skin, and nails. It is made with premium ingredients sourced from trusted suppliers, and is free from common allergens, artificial additives, and unnecessary fillers.

What We Like
Supports joint functionality and comfort
Potentially supports immune and respiratory health
Supports tissue containing significant amounts of collagen and keratin, including hair, skin, and nails

Organic Sulfur Crystals, Premium MSM Supplement - 1 LBS Pack

ORGSFR-1pk
1 Pound (Pack of 1)
Organic Sulfur Crystals, Premium MSM Supplement - 1 LBS Pack Cover
Organic Sulfur Crystals - 99% Pure MSM Crystals, Premium MSM Supplement - Excellent Quality and Absorption. 1 LB Pack.

The Organic Sulfur Crystals by HAPPY BODY are a premium quality, additive-free MSM supplement that provides a minimum of 99.9% pure MSM. The product is certified for purity by 3rd-party independent labs, is free from gluten and GMO, and vegan-friendly. Each bag provides 45 - 90 days of supply, and the product is easy to use by taking a 1/4 to 1/2 teaspoon twice daily with water or juice. The product also comes with a 100% satisfaction guarantee.

What We Like
Premium quality, additive-free MSM supplement
Minimum of 99.9% pure MSM with no fillers, additives or binders
Easy to use by taking a 1/4 to 1/2 teaspoon twice daily with water or juice
Certified for purity by 3rd-party independent labs and free from gluten and GMO
Comes with a 100% satisfaction guarantee
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is it good to take MSM powder?

MSM powder has shown to have anti-inflammatory and antioxidant effects. It contains sulfur, which plays a crucial role in the production of collagen, glucosamine, and immunoglobulins. These components are essential for healthy bones, joints, and a strong immune system.

2. What are the side effects of MSM powder?

Some people may experience side effects from taking MSM powder, such as nausea, diarrhea, bloating, and stomach discomfort. When applied to the skin, MSM is generally safe when used with other ingredients for a limited duration.

3. What is the best way to use MSM powder?

To start, dissolve 1/4 teaspoon of MSM powder in a glass of water twice per day. Take the first dose in the morning and the second later in the afternoon, on an empty stomach. After 2-3 days, you can gradually increase the dosage. It's important to take MSM twice daily and avoid taking it too late in the day or evening.

4. What to avoid when taking MSM?

When taking MSM, it is advisable to avoid medications that treat or prevent blood clots, such as warfarin, enoxaparin, dalteparin, apixaban, dabigatran, and rivaroxaban. It is also recommended to avoid NSAIDs like ibuprofen or naproxen, as well as other herbal supplements.

5. Who should not use MSM?

If you are pregnant or breastfeeding, it is recommended to avoid using MSM as there is insufficient reliable information on its safety during these periods. It is always best to err on the side of caution and refrain from using MSM in such situations.

6. What happens when you start taking MSM?

Studies have shown that taking MSM can significantly reduce inflammation in the body. It can also help inhibit the breakdown of cartilage, which is important for protecting the ends of bones in joints.

Editor's Notes

During our powder msm supplement research, we found 24 powder msm supplement products and shortlisted 10 quality products. We collected and analyzed 157,051 customer reviews through our big data system to write the powder msm supplements list. We found that most customers choose powder msm supplements with an average price of $18.90.

The powder msm supplements are available for purchase. We have researched hundreds of brands and picked the top brands of powder msm supplements, including Doctor's Best, BulkSupplements, Nutricost, NOW Foods, PURE ORIGINAL INGREDIENTS. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.