Best Hypoallergenic Hand Sanitizers of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 9, 2026

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Hypoallergenic hand sanitizers are a great option for people who have sensitive skin or allergies to certain ingredients commonly found in traditional hand sanitizers. These products are formulated without harsh chemicals and fragrances that can cause irritation or allergic reactions. They still effectively kill germs and bacteria while being gentle on the skin. Hypoallergenic hand sanitizers come in various forms, including gels, sprays, and wipes, and are perfect for use at home, work, or on-the-go. They are a must-have for anyone looking for a safer and more comfortable way to keep their hands clean and germ-free.

At a Glance: Our Top Picks

The Honest Company Hand Sanitizer Spray Cover #TOP 1
The Honest Company Hand Sanitizer Spray
ftb score rating icon 9.8
Wet Ones Antibacterial Hand Wipes, Fresh Scent Cover #TOP 2
Wet Ones Antibacterial Hand Wipes, Fresh Scent
ftb score rating icon 9.7
Wet Ones Antibacterial Hand Wipes Fresh Scent 40 ct. Canister Cover #TOP 3
Wet Ones Antibacterial Hand Wipes Fresh Scent 40 ct. Canister
ftb score rating icon 9.5

Top 3 Hypoallergenic Hand Sanitizers

#TOP 1

The Honest Company Hand Sanitizer Spray

B07CL6X8SZ
Free & Clear
2 Fl Oz (Pack of 1)
The Honest Company Hand Sanitizer Spray Cover
The Honest Company Plant-Based Hand Sanitizer Spray, Kills 99.9% of Germs, Hypoallergenic, Quick-drying, Moisturizing, Fragrance-Free, 2 fl oz

The Honest Company Hand Sanitizer Spray, also known as Honest Hand Sanitizer Spray, is a plant-based hand sanitizer that effectively kills 99.9% of germs and bacteria. This hypoallergenic and dermatologist-tested spray is made with naturally-derived glycerin and aloe, leaving your skin feeling soft and moisturized. The quick-drying gel sanitizes your hands without leaving a sticky residue, making it convenient for everyday use. Suitable for ages 6 and up, this hand sanitizer is made without triclosan, parabens, synthetic fragrances, and benzalkonium chloride. The packaging may vary, but the great naturally-derived ingredients remain the same. Keep your hands clean and protected with The Honest Company Hand Sanitizer Spray.

What We Like
Effectively kills 99.9% of germs
Hypoallergenic and moisturizing
Quick-drying without sticky residue
#TOP 2

Wet Ones Antibacterial Hand Wipes, Fresh Scent

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wipes
Wet Ones Antibacterial Hand Wipes, Fresh Scent Cover
Wet Ones Travel Packs Fresh Scent 10 Packs, 200 Wipes

Wet Ones Antibacterial Hand Wipes are convenient travel packs that kill 99.99% of germs while wiping away dirt and messes. The moisturizing aloe formula won't dry out or irritate your hands like hand sanitizers can. The resealable flap prevents wipes from drying out and the unique Wet Lock Seal retains moisture in between uses. Pediatrician tested, hypoallergenic and paraben-free, these wipes leave skin feeling clean and refreshed with a light fresh fragrance.

What We Like
Effective against germs
Convenient for on-the-go use
Moist and pleasant scent
Bulk buying offers savings
Thick and large wipes
#TOP 3

Wet Ones Antibacterial Hand Wipes Fresh Scent 40 ct. Canister

wipes
Wet Ones Antibacterial Hand Wipes Fresh Scent 40 ct. Canister Cover
Wet Ones Antibacterial Hand Wipes, Fresh Scent Wipes | Antibacterial Wipes, Hand Sanitizer Wipes, Wet Ones Wipes, 40 ct. Canister (6 pack)

Wet Ones Fresh Scent Wipes are designed to help you quickly kill 99.99% of germs, making them perfect for keeping your hands clean and safe from harmful bacteria. These wipes also remove dirt and messes, so you don’t have to worry about sticky or grimy hands when you're on the go. You’ll enjoy the softness and smooth feel they leave behind, so your skin won’t feel rough or dry after use. Plus, the fresh scent with a hint of aloe adds a pleasant touch, keeping your hands smelling clean and feeling refreshed.

What We Like
Effective germ-killing
Removes dirt and mess
Softens and smooths skin
Fresh aloe scent
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Can a person be allergic to hand sanitizer?

It's possible to be allergic to the ingredients in hand sanitiser, say experts. And using too much sanitiser, or the wrong kind, can ruin your skin.

2. What is it called when you are allergic to hand sanitizer?

Irritant Contact Dermatitis Caused by Hand Sanitizer Use and Handwashing During the COVID-19 Pandemic.

3. What hand sanitizer is best for eczema?

Best hand sanitizers for eczemaBaby Dove Dove Sanitizer Fragrance FreeThe Honest Company Hand Sanitizer SpraySensitive Skin Hypoallergenic Hand Sanitizer, Alcohol-, 14.2oz, case/16Honest Hand Sanitizer SprayBabyganics Alcohol-Free Foaming Hand SanitizerBabyganics Alcohol Free Foaming Hand SanitizerDial Professional Antibacterial Hand Sanitizer GelDial Antibacterial with Moisturizers Gel Hand SanitizerDial Hand Sanitizer Gel DIA31859pullio Antibacterial Hand Wipes Citrus ScentDial Professional Antibacterial Gel Hand Sanitizer W Moisturizers 16oz Pump Fragrance-Free 8 ct (Dia 00213)Sun Bum Hand SanitizerDial Antibacterial Hand Sanitizer 4 oz 00685EO Products Hand Sanitizer Gel - Unscented - 32 ozDial Antibacterial Gel Hand Sanitizer with Moisturizers, 4 oz Flip-Top Bottle, 24/Ctn - DIA00685Germ Attack Antibacterial Gel Hand SanitizerNoodle Boo Instant Hand Sanitizerpullio Antibacterial Hand Wipes Peppermint ScentHand Sanitizer Spray Unscented Hypoallergenic. Eczema Honey Hand Sanitizer Gel.Honest Hand Sanitizer Spray.Dove Beauty Nourishing Hand Sanitizer.Suave Hand Sanitizer Unscented.Megababe Squeaky Clean Hand Sanitizer.Purell Naturals Hand Sanitizer.

Editor's Notes

During our hypoallergenic hand sanitizer research, we found 24 hypoallergenic hand sanitizer products and shortlisted 3 quality products. We collected and analyzed 394,267 customer reviews through our big data system to write the hypoallergenic hand sanitizers list. We found that most customers choose hypoallergenic hand sanitizers with an average price of $16.79.

The hypoallergenic hand sanitizers are available for purchase. We have researched hundreds of brands and picked the top brands of hypoallergenic hand sanitizers, including The Honest Company, Wet Ones. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.