Best Hypoallergenic Laundry Stain Removers of 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.
Hypoallergenic laundry stain removers are becoming increasingly popular among consumers who suffer from allergies or have sensitive skin. These products are specially formulated to remove tough stains from clothes without irritating the skin or causing allergic reactions. They are free from common allergens such as fragrances, dyes, and harsh chemicals, making them safe for use on all types of fabrics. Hypoallergenic laundry stain removers are available in various forms such as sprays, gels, and powders, making them convenient to use. They are a great alternative for those who want to keep their clothes clean and fresh without compromising their health.
At a Glance: Our Top Picks
Top 7 Hypoallergenic Laundry Stain Removers
Dapple Baby Stain Remover Spray, Fragrance Free, 16.9 Fl Oz
The Dapple Baby Stain Remover Spray is a plant-based and hypoallergenic laundry stain remover, specifically designed for baby clothes and cloth diapers. It's both safe and effective, made without harsh chemicals, parabens, sulfates, phthalates, mineral oil, synthetic dyes and fragrances, chlorine, alcohol, SLS, SLES, MEA, DEA, TEA. The fragrance-free formula is pediatrician and dermatologist tested, versatile, and baby friendly, working on tough baby laundry stains like poop, formula, and spit-up compared to leading brands.
Dr. Brown's Stain and Odor Remover
Dr. Brown's Stain Remover is specially designed for cleaning baby clothes and other family items. Its baby-friendly formula ensures safety, so you can feel good about using it on your little one's garments. This product is hypoallergenic and fragrance-free, providing a clean without irritating scents. Made with plant-derived cleansers, it effectively tackles tough stains and odors from messes like breast milk or food spills. You’ll appreciate the convenience of the spray nozzle, which allows for targeted application on concentrated stains or wider coverage for larger areas.
Dreft Stain Remover for Baby Clothes
Dreft Baby Stain Remover is a set of two 24oz bottles of stain remover spray and a to-go instant stain remover pen. It is specifically formulated for tough stains on cloth diapers, infants' and children's clothing, bedding, and blankets. Made with plant-based ingredients, it is free of dyes, chlorine, and phosphates, making it hypoallergenic. Dreft Baby Stain Remover is a USDA certified biobased product and is from the #1 pediatrician recommended baby detergent brand. You can add it to your subscriptions to save money and never run out. Proudly made in the USA by Nehemiah Manufacturing Co, a second chance company, every purchase helps provide jobs for Second Chance Employees.
Kelebs Citrus Laundry Soap Bar
Kelebs Laundry Soap offers a gentle solution for your laundry needs, especially if you have sensitive skin. Its eco-friendly formula not only cleans effectively but also minimizes your environmental impact, making it a smart choice for conscious consumers. The refreshing citrus scent leaves your clothes smelling fresh and clean. Additionally, its powerful stain removal capabilities mean that tough stains on underwear and collars are no match for this detergent bar, ensuring your garments look their best with minimal effort.
Aleva Naturals Stain Remover and Laundry Bar
Aleva Naturals Stain Remover is a gentle and effective laundry bar designed for removing tough stains from clothing and fabrics. Made with natural and organic ingredients, it is gentle on your baby's delicate skin while being tough on spit-up, food mush, and soiled clothes. The bar is skin-friendly, perfect for sensitive and eczema-prone skin, and easy to use for hand washing delicates. Its plant-based formula makes it vegan certified and safe for cloth diapers. Ideal for travel, it offers a convenient alternative to regular laundry detergent.
AspenClean Oxygen Bleach Powder and Stain Remover - 45 Loads
AspenClean's Oxygen Bleach Powder and Stain Remover is a powerful and effective laundry solution that is gentle on skin and the environment. This laundry powder is made with high quality plant-based ingredients, making it biodegradable, recyclable and plastic-free. It is tough on stains and will leave clothes whiter and brighter using the natural power of mineral-based ingredients and enzymes. The bleach stain remover is safe for all loads of laundry, including delicate and colored fabrics.
Puracy Spot Remover & Carpet Cleaner
Puracy Carpet Cleaner is a powerful cleaning spray that removes hundreds of stains and odors in seconds. Its no-rinse formula makes it effortless to use on fresh stains, and it contains powerful plant-powered enzymes and deodorizers. Simply spray, wipe, and watch stains vanish. It works wonders on a wide range of washable fabrics, including carpets, upholstery, clothing, bedding, and car seats. Puracy Carpet Cleaner is crafted with 99.51% natural ingredients, making it hypoallergenic, biodegradable, vegan, and cruelty-free. With its versatile cleaning power, it's the perfect solution for all your carpet and fabric cleaning needs.
Frequently Asked Questions (FAQs)
1. Is OxiClean hypoallergenic?
Many people really love that Oxiclean does not contain chlorine bleach, and therefore is safe to use for both whites and colors. There are several types of the product available, including original, a free version, which is free of dyes and perfumes and therefore hypoallergenic, and one for babies.
2. What is an organic stain remover?
For tougher stains on sinks or stove tops, mix 2/3 cup baking soda, 1/2 cup organic vegetable-based liquid soap and enough water to form a paste. Add 2 tablespoons organic white vinegar, apply the paste to the surface and scrub with a scouring sponge or a stiff brush.
3. What brand of detergent can remove stain completely?
Tide Ultra Stain Release was a better overall cleaner than any other detergent we tested. Although some detergents removed more of certain stains, Tide Ultra Stain Release removed more from a greater number of stains than any of the others.
During our hypoallergenic laundry stain remover research, we found 24 hypoallergenic laundry stain remover products and shortlisted 7 quality products. We collected and analyzed 73,298 customer reviews through our big data system to write the hypoallergenic laundry stain removers list. We found that most customers choose hypoallergenic laundry stain removers with an average price of $12.86.
The hypoallergenic laundry stain removers are available for purchase. We have researched hundreds of brands and picked the top brands of hypoallergenic laundry stain removers, including Dapple, Dr. Brown's, Dreft, KELEBS, Aleva Naturals. The seller of top 1 product has received honest feedback from 137 consumers with an average rating of 4.5.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.