Best Hypoallergenic Laundry Stain Removers of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 6, 2025

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Hypoallergenic laundry stain removers are becoming increasingly popular among consumers who suffer from allergies or have sensitive skin. These products are specially formulated to remove tough stains from clothes without irritating the skin or causing allergic reactions. They are free from common allergens such as fragrances, dyes, and harsh chemicals, making them safe for use on all types of fabrics. Hypoallergenic laundry stain removers are available in various forms such as sprays, gels, and powders, making them convenient to use. They are a great alternative for those who want to keep their clothes clean and fresh without compromising their health.

At a Glance: Our Top Picks

Dapple Baby Stain Remover Spray, Fragrance Free, 16.9 Fl Oz Cover #TOP 1
Dapple Baby Stain Remover Spray, Fragrance Free, 16.9 Fl Oz
ftb score rating icon 9.8
Dr. Brown's Stain and Odor Remover Cover #TOP 2
Dr. Brown's Stain and Odor Remover
ftb score rating icon 9.7
Dreft Stain Remover for Baby Clothes Cover #TOP 3
Dreft Stain Remover for Baby Clothes
ftb score rating icon 9.5

Top 7 Hypoallergenic Laundry Stain Removers

#TOP 1

Dapple Baby Stain Remover Spray, Fragrance Free, 16.9 Fl Oz

80042
Multicolor
Dapple Baby Stain Remover Spray, Fragrance Free, 16.9 Fl Oz Cover
Stain Remover Spray by Dapple Baby, Fragrance Free, 16.9 Fl Oz Spray Bottle - Plant-Based & Hypoallergenic - Baby Laundry Stain Remover for Clothes & Cloth Diapers

The Dapple Baby Stain Remover Spray is a plant-based and hypoallergenic laundry stain remover, specifically designed for baby clothes and cloth diapers. It's both safe and effective, made without harsh chemicals, parabens, sulfates, phthalates, mineral oil, synthetic dyes and fragrances, chlorine, alcohol, SLS, SLES, MEA, DEA, TEA. The fragrance-free formula is pediatrician and dermatologist tested, versatile, and baby friendly, working on tough baby laundry stains like poop, formula, and spit-up compared to leading brands.

What We Like
Safe and effective for the whole family
Powered by plants to work on tough baby laundry stains
Free of harsh chemicals, synthetic dyes, and fragrances
#TOP 2

Dr. Brown's Stain and Odor Remover

Dr. Brown's
HG125-P6
White
Dr. Brown's Stain and Odor Remover Cover
Dr. Brown's Laundry Spray Stain and Odor Remover for Baby Clothes, Hypoallergenic, Fragrance-Free, 16 fl oz, 1 Pack

Dr. Brown's Stain Remover is specially designed for cleaning baby clothes and other family items. Its baby-friendly formula ensures safety, so you can feel good about using it on your little one's garments. This product is hypoallergenic and fragrance-free, providing a clean without irritating scents. Made with plant-derived cleansers, it effectively tackles tough stains and odors from messes like breast milk or food spills. You’ll appreciate the convenience of the spray nozzle, which allows for targeted application on concentrated stains or wider coverage for larger areas.

What We Like
Safe for baby clothes
Hypoallergenic and fragrance-free
Plant-based ingredients
Effective against tough stains
Easy spray application
#TOP 3

Dreft Stain Remover for Baby Clothes

SCOBUTY
White
Dreft Stain Remover for Baby Clothes Cover
Dreft Stain Remover for Baby Clothes, Fragrance Free and Hypoallergenic Baby Stain Remover Spray Plus Travel Size Stain Treater Pen, 24 Fl Oz ( Pack of 2 + Stain Pen)

Dreft Baby Stain Remover is a set of two 24oz bottles of stain remover spray and a to-go instant stain remover pen. It is specifically formulated for tough stains on cloth diapers, infants' and children's clothing, bedding, and blankets. Made with plant-based ingredients, it is free of dyes, chlorine, and phosphates, making it hypoallergenic. Dreft Baby Stain Remover is a USDA certified biobased product and is from the #1 pediatrician recommended baby detergent brand. You can add it to your subscriptions to save money and never run out. Proudly made in the USA by Nehemiah Manufacturing Co, a second chance company, every purchase helps provide jobs for Second Chance Employees.

What We Like
Plant-based ingredients
Hypoallergenic
Effective for tough stains
#TOP 4

Kelebs Citrus Laundry Soap Bar

KELEBS
9 Count (Pack of 1)
Kelebs Citrus Laundry Soap Bar Cover
Kelebs Laundry Soap Bar - Hypoallergenic and Organic Citrus Formula for Sensitive Skin - Delicate Stain Remover for Clothes, Underwear, Collar - 9 Bars

Kelebs Laundry Soap offers a gentle solution for your laundry needs, especially if you have sensitive skin. Its eco-friendly formula not only cleans effectively but also minimizes your environmental impact, making it a smart choice for conscious consumers. The refreshing citrus scent leaves your clothes smelling fresh and clean. Additionally, its powerful stain removal capabilities mean that tough stains on underwear and collars are no match for this detergent bar, ensuring your garments look their best with minimal effort.

What We Like
Gentle on sensitive skin
Eco-friendly formula
Refreshing citrus scent
Effective stain removal
#TOP 5

Aleva Naturals Stain Remover and Laundry Bar

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Unbleached
Aleva Naturals Stain Remover and Laundry Bar Cover
Stain Remover and Laundry Bar | Removes Stains from Clothing and Fabrics | Hand Wash Delicates | Targets Spit-Up, Food Mush and Soiled Clothing | Natural and Organic Ingredients | (220 grams)

Aleva Naturals Stain Remover is a gentle and effective laundry bar designed for removing tough stains from clothing and fabrics. Made with natural and organic ingredients, it is gentle on your baby's delicate skin while being tough on spit-up, food mush, and soiled clothes. The bar is skin-friendly, perfect for sensitive and eczema-prone skin, and easy to use for hand washing delicates. Its plant-based formula makes it vegan certified and safe for cloth diapers. Ideal for travel, it offers a convenient alternative to regular laundry detergent.

What We Like
Gentle on baby's skin
Removes tough stains
Skin-friendly
#TOP 6

AspenClean Oxygen Bleach Powder and Stain Remover - 45 Loads

AspenClean
AspenClean Oxygen Bleach Powder and Stain Remover - 45 Loads Cover
Unscented Oxygen Bleach Powder and Color Safe Stain Remover by AspenClean, Zero plastic, EWG Verified™, Vegan, Hypoallergenic, Bleach Alternative - 45 Loads

AspenClean's Oxygen Bleach Powder and Stain Remover is a powerful and effective laundry solution that is gentle on skin and the environment. This laundry powder is made with high quality plant-based ingredients, making it biodegradable, recyclable and plastic-free. It is tough on stains and will leave clothes whiter and brighter using the natural power of mineral-based ingredients and enzymes. The bleach stain remover is safe for all loads of laundry, including delicate and colored fabrics.

What We Like
EWG VERIFIED with an A-rating verification by the Environmental Working Group
NO HARSH CHEMICALS & HYPOALLERGENIC, gentle on skin
Tough on stains, leaving clothes whiter and brighter in just 1 wash
ZERO PLASTIC, biodegradable, plant-based ingredients with compostable container
SAFE FOR ALL LOADS OF LAUNDRY, including delicate and colored fabrics
#TOP 7

Puracy Spot Remover & Carpet Cleaner

PCSR25-1
Puracy Spot Remover & Carpet Cleaner Cover
Puracy 25oz Instant Spot Remover & Fabric Stain Remover - Cleaning Spray, Stain Spray - Car Cleaner - Carpet Stain Remover, Carpet Spot Cleaner, Carpet Cleaning Solution, Free & Clear, 25 Fl Oz

Puracy Carpet Cleaner is a powerful cleaning spray that removes hundreds of stains and odors in seconds. Its no-rinse formula makes it effortless to use on fresh stains, and it contains powerful plant-powered enzymes and deodorizers. Simply spray, wipe, and watch stains vanish. It works wonders on a wide range of washable fabrics, including carpets, upholstery, clothing, bedding, and car seats. Puracy Carpet Cleaner is crafted with 99.51% natural ingredients, making it hypoallergenic, biodegradable, vegan, and cruelty-free. With its versatile cleaning power, it's the perfect solution for all your carpet and fabric cleaning needs.

What We Like
No-rinse formula
Effortless stain removal
Removes hundreds of stains & odors
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is OxiClean hypoallergenic?

Many people really love that Oxiclean does not contain chlorine bleach, and therefore is safe to use for both whites and colors. There are several types of the product available, including original, a free version, which is free of dyes and perfumes and therefore hypoallergenic, and one for babies.

2. What is an organic stain remover?

For tougher stains on sinks or stove tops, mix 2/3 cup baking soda, 1/2 cup organic vegetable-based liquid soap and enough water to form a paste. Add 2 tablespoons organic white vinegar, apply the paste to the surface and scrub with a scouring sponge or a stiff brush.

3. What brand of detergent can remove stain completely?

Tide Ultra Stain Release was a better overall cleaner than any other detergent we tested. Although some detergents removed more of certain stains, Tide Ultra Stain Release removed more from a greater number of stains than any of the others.

Editor's Notes

During our hypoallergenic laundry stain remover research, we found 24 hypoallergenic laundry stain remover products and shortlisted 7 quality products. We collected and analyzed 73,298 customer reviews through our big data system to write the hypoallergenic laundry stain removers list. We found that most customers choose hypoallergenic laundry stain removers with an average price of $12.86.

The hypoallergenic laundry stain removers are available for purchase. We have researched hundreds of brands and picked the top brands of hypoallergenic laundry stain removers, including Dapple, Dr. Brown's, Dreft, KELEBS, Aleva Naturals. The seller of top 1 product has received honest feedback from 137 consumers with an average rating of 4.5.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.