Best Refill Hand Sanitizers of 2025

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Refill hand sanitizers are an essential item for anyone looking to maintain proper hygiene during the ongoing pandemic. These products are designed to fill up empty hand sanitizer bottles, making them a cost-effective and eco-friendly solution. Refill hand sanitizers are available in various sizes and come in gel or liquid forms. They contain at least 60% alcohol, which is the recommended percentage for killing germs and bacteria. These sanitizers are easy to use and can be carried around in a purse or backpack. With refill hand sanitizers, individuals can ensure that they always have a supply of hand sanitizer to keep themselves and others safe.
At a Glance: Our Top Picks
Top 10 Refill Hand Sanitizers
Clean Revolution Liquid Gel Hand Sanitizer
Clean Revolution Hand Sanitizer offers a powerful solution to keep your hands germ-free, effectively eliminating 99.9% of germs with its 70% medical-grade ethanol. This high-quality formula ensures safety, making it suitable for use in medical facilities. Additionally, it includes Aloe Vera and Vitamin E, which help keep your skin moisturized and soft, even after frequent use. You can also save money and reduce waste, as one gallon can refill over 10 dispensers, minimizing the reliance on single-use plastic bottles. This sanitizer is cruelty-free, adhering to the latest green chemistry practices.
Purell 64 Oz. Hand Sanitizer Gel
The Purell Hand Sanitizer Gel is a trusted choice that many hospitals and healthcare professionals rely on. This advanced formula effectively kills germs, providing you with peace of mind in maintaining cleanliness. It's perfect for quick use when soap and water are not available, making it convenient for everyday situations. With its refreshing gel texture, it leaves your hands feeling clean without any sticky residue. By choosing this hand sanitizer, you’re not only protecting yourself but also contributing to a healthier environment around you.
Nutri Advanced Instant Hand Sanitizer
The Nutri Hand Sanitizer Gel is designed with a gentle formula that prioritizes your skin's health. Free from harsh chemicals like parabens and phthalates, it ensures that your hands remain moisturized and irritation-free after use. The convenient 64 oz refill bottle comes with a pump for easy dispensing, making it simple to apply the right amount without any mess. This product not only sanitizes effectively but also keeps your skin feeling fresh and comfortable, allowing you to maintain hygiene without sacrificing skin care.
Babyganics Foaming Hand Sanitizer Refill
The Babyganics Hand Sanitizer Refill is a convenient and effective way to keep your hands clean and germ-free. Made with plant-derived ingredients, this alcohol-free sanitizer kills 99.9% of common bacteria without drying out your skin. The moisturizing, foaming formula leaves your hands feeling soft and refreshed. With no parabens, sulfates, phthalates, fragrances, or dyes, this sanitizer is non-allergenic and safe for the whole family to use. Plus, it's cruelty-free, as it is not tested on animals. Keep your hands clean and protected with the Babyganics Hand Sanitizer Refill.
JERMEE Moisturizing Hand Sanitizer Gel
JERMEE Moisturizing Hand Sanitizer Gel is a no-rinse formula that kills 99.99% of germs without soap & water, enriched with moisturizers, Vitamin E, and Aloe Vera to keep your hands soft and moisturized. Its quick-drying non-drip gel allows you to spread it evenly over your hands and nails, quickly removing dirt, grease, and grime without leaving any sticky residue. This bulk sanitizer is perfect for frequent use, safe, and effective. Suitable for homes, classrooms, and office reception areas.
PURELL Advanced Hand Sanitizer Green Certified Gel 1000 mL Refill (Pack of 8)
PURELL Gel Refill Pack is a trusted hand sanitizer used by hospitals, proven to eliminate 99.99% of illness-causing germs without harming your skin. It is free of harmful chemicals like dye, triclosan, parabens, and phthalates. This ECOLOGO Certified sanitizer is made with naturally renewable alcohol, with 93% biobased content. Compatible with various dispensers, this pack includes eight 1000 mL refills, ensuring long-lasting germ protection.
PURELL Advanced Hand Sanitizer Gel
PURELL Hand Sanitizer Gel is an essential tool for maintaining hygiene. It effectively kills 99.99% of germs, ensuring your hands stay clean when soap and water are not accessible. With its refreshing scent, it leaves your hands smelling great while evaporating quickly for convenience. The gentle formula, enriched with four moisturizers, ensures your skin remains soft even with frequent use. Plus, it is free from harsh chemicals, preventing dryness or irritation. Each 64oz bottle comes with a handy pump for easy dispensing, making it perfect for home or office use.
PURELL Advanced Hand Sanitizer Naturals
PURELL Hand Sanitizer Naturals is designed to help you and your loved ones effectively eliminate germs from your hands. With its naturally derived alcohol, it offers double the sanitizing power, ensuring a thorough clean. The product is ECOLOGO certified and includes essential oils and natural skin conditioners, making it gentle on your skin while being tough on germs. It is free from harmful ingredients like triclosan and parabens. The convenient one-liter pump bottle is perfect for regular use in homes, schools, and offices, providing easy access for everyone whenever they need to sanitize.
PURELL Advanced Hand Sanitizer Kit
The PURELL Hand Sanitizer Kit is designed to help you reduce your environmental footprint while keeping your hands clean. With this refillable kit, you can easily fill two travel-sized bottles from the larger 24 fl oz container, minimizing single-use plastic waste. The durable aluminum bottles are not only TSA-friendly for travel but also designed to be leak-proof. This sanitizer effectively kills 99.99% of germs and features a gentle formula with 93% biobased content, ensuring your hands remain soft and moisturized after use.
HAAN Hydrating Hand Sanitizer Refill
HAAN Hand Sanitizer is a travel-friendly solution that you can take anywhere. This compact 1.01 fl.oz. sanitizer fits easily in your purse or pocket and provides over 400 sprays, ensuring you always have it on hand. When you run out, you can conveniently refill it up to three times with the refill bag. The natural formula contains 99.5% ingredients of natural origin, which means you can keep your hands clean and moisturized without any stickiness. Plus, the refreshing scent evaporates quickly, making it perfect for on-the-go sanitizing when soap and water aren’t available.
Frequently Asked Questions (FAQs)
1. Can hand sanitizer bottles be refilled?
Refilled bottles are meant for circulation for up to 90 days. Any bottles showing any physical damage to the bottle, pump or label during the first 90 days should be discarded. Please attach a sticker with the date of first refill somewhere on the bottle.
2. Can you refill hand sanitizer dispenser?
Businesses can provide safe and effective hand sanitizer by: Not mixing hand sanitizer formulas in dispensers or bottles over time. Not refilling branded bottles or dispensers with other formulas.
3. Can Purell refills be refilled?
They are designed to be easy to install and maintain. 1200 mL Refill for PURELL TFX™ Touch-Free Dispensers (2720-12, 2780-12). Holds up to 1000 uses....About this product.
4. How do you refill a hand sanitizer cartridge?
Purell Hand Sanitizer RefillHygienex Hand Sanitizer Liquid Refill 1 Gallon 128 Oz. Scented with Eucalyptus OilDial Eco-Smart Gel Hand Sanitizer Refill, Fragrance-Free, 15 Oz HAAN SprayPurell Advanced Foam Hand Sanitizer LTX-12Gojo Industries Inc PURELL LTX12 Advanced Sanitizer Gel Refill GOJ190302CTOlika Hydrating Hand Sanitizer RefillPurell Advanced FMX-12 Foam Hand Sanitizer RefillKutol Hand Sanitizer Wall Refill 68241Naturewell Advanced Liquid Hand Sanitizer RefillWish Refill Pack 33.8oz Scented with Extra Moisturizer 1 Liter Hand SanitizerPacific Blue Ultra Foam Hand Sanitizer RefillPURELL Hand Sanitizer Foam RefillAmass Four Thieves Hand Sanitizer TravelPurell Advanced Green Hand Sanitizer Refill GelPurell Advanced Foam Hand SanitizerThe Container Store 9 oz. Shimmy Home Hand Sanitizer RefillPurell Advanced Hand Sanitizer Green Certified Gel Refill BottleZEP 128 oz. Alcohol Hand Sanitizer Spray Refill
During our refill hand sanitizer research, we found 24 refill hand sanitizer products and shortlisted 10 quality products. We collected and analyzed 41,787 customer reviews through our big data system to write the refill hand sanitizers list. We found that most customers choose refill hand sanitizers with an average price of $15.22.
The refill hand sanitizers are available for purchase. We have researched hundreds of brands and picked the top brands of refill hand sanitizers, including Clean Revolution, Purell, Nutri, Babyganics, JERMEE. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.