Best Moisturizing Hand Sanitizers of 2025

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Moisturizing hand sanitizers are a great way to keep hands clean and germ-free while also preventing dryness and irritation. These sanitizers contain moisturizing ingredients such as aloe vera, vitamin E, and glycerin, which help to hydrate and soothe the skin. Unlike traditional hand sanitizers that can leave hands feeling dry and rough, moisturizing hand sanitizers provide a more gentle and nourishing experience. They come in a variety of scents and sizes, making them a convenient option for on-the-go use. Overall, moisturizing hand sanitizers are a must-have for anyone looking to keep their hands clean and healthy.
At a Glance: Our Top Picks
Top 10 Moisturizing Hand Sanitizers
Purell Moisturizing Foam Hand Sanitizer Pack of 3
The Purell Advanced Hand Sanitizer 2in1 Moisturizing Foam is a luxurious foam formula that kills 99.99% of germs, while keeping hands healthy and soft. Its unique blend of hydrating ingredients improves skin health in just 5 days. This 10 oz foam pump bottle is perfect for home or office use, and leaves hands feeling clean with no sticky residue. It is free of harsh preservatives and does not contain dye, triclosan, parabens, or phthalates.
Germ-X Advanced Hand Sanitizer 1L
Germ-X Advanced Hand Sanitizer with Aloe in 1 Liter size eliminates over 99.99% of germs in just 15 seconds. The advanced formula contains aloe and 70% alcohol, ensuring your hands are clean and moisturized. Made in the USA, this hand sanitizer is easy to use with its convenient pump.
Bath + Body Works Holiday Hand Sanitizer Set
The Bath + Body Works Sanitizer Set includes five festive 1-ounce bottles, perfect for the holiday season. You'll enjoy a variety of scents, including Tis the Season and Gingerbread Bakery, making them great for all family members. Each bottle is designed to fit into Bath and Body Works Pocketbac Holders, although the holders are sold separately. These sanitizers are infused with nourishing ingredients like shea extract and vitamin E, ensuring your hands stay clean and moisturized wherever you go. With these convenient mini sanitizers, you can keep your hands fresh while enjoying delightful holiday aromas.
Germ-x Nourish Hand Sanitizer
Germ-x Nourish Hand Sanitizer is a 2-in-1 moisturizing and sanitizing formula that provides reliable protection against common germs. With its fast and effective formula, it kills 99.99% of germs without water in just 15 seconds, while also moisturizing and softening the skin. The non-greasy, citrus-scented sanitizer is enriched with Shea butter, Vitamin E, and Aloe, leaving your hands feeling soft and refreshed. This hypoallergenic sanitizer is perfect for on-the-go use when soap and water are not available. Germ-x Nourish Hand Sanitizer is an essential back-to-school supply that will help keep your family safe and healthy.
Hempz Fresh Citrus Hand Sanitizer
The Hempz Hand Sanitizer offers a refreshing and effective way to keep your hands clean. It eliminates 99.99% of germs, ensuring that your hands are not only sanitized but also soft and moisturized. This product is made with a blend of essential extracts that help condition and hydrate dry skin, making it a great choice for those who wash their hands frequently. Additionally, it is vegan, gluten-free, and free of harmful parabens, allowing you to use it with peace of mind, knowing it’s safe for both you and the environment.
Purell 2in1 Moisturizing Hand Sanitizer Gel, 12 oz (Pack of 4)
Keep your hands clean and moisturized with Purell 2in1 Moisturizing Advanced Hand Sanitizer Gel. This unique hand sanitizer formulation kills 99.99% of germs while nourishing your skin with up to 2X more moisture. Its hydrating ingredients leave your hands feeling soft and clean without any sticky residue. The 12 oz pump bottle is perfect for tabletops and workstations where hand sanitizer is needed.
Dove Shea Butter Hand Sanitizer
Dove Hand Sanitizer effectively fights germs with a remarkable 99.99% effectiveness. This innovative gel not only kills bacteria but is also designed to keep your skin soft and moisturized for up to eight hours. Thanks to its unique Moisture Renew Blend, your hands will feel comfortable and hydrated after each use. Plus, it meets the FDA and CDC's recommended alcohol levels, ensuring you stay safe. With its PETA-certified cruelty-free formulation and eco-friendly packaging, you can feel good about using this product daily.
Purell 2in1 Moisturizing Hand Sanitizer
Purell Moisturizing Hand Sanitizer offers a dual-action formula that effectively kills 99.99% of germs while also nourishing your skin. You’ll appreciate how it leaves your hands feeling clean and soft without any sticky residue. Its unique blend of hydrating ingredients not only fights germs but also enhances your skin's condition with regular use. The portable squeeze bottle is perfect for taking on-the-go, making it easy to keep handy in your desk drawer, glovebox, or bag whenever you need to sanitize.
DERMAGLOVE Hand Science Moisturizing Gel
DERMAGLOVE Gel Sanitizer is a unique two-in-one product that not only sanitizes your hands but also promotes skin health. With its advanced formula, it creates a protective barrier that helps repair and nourish damaged skin. You’ll benefit from the addition of vitamins A, C, and E, which deliver essential nutrients while keeping your hands moisturized. This skin-safe sanitizer is also cruelty-free, ensuring that the ingredients work in harmony with your skin's natural chemistry. Enjoy the peace of mind that comes with effective protection against harmful contaminants without sacrificing skin health.
Champagne Toast Hand Sanitizers by Bath + Body Works
Experience the delightful scent of the Bath + Body Works Hand Sanitizers with their Champagne Toast fragrance. You’ll enjoy a refreshing blend of bubbly champagne, sweet berries, and tangy tangerine every time you use it. These hand sanitizers not only smell great but also keep your hands clean and germ-free, providing a convenient way to maintain hygiene on the go. Perfect for everyday use, they fit easily in your bag, making them accessible whenever you need them. Treat yourself to a little luxury while ensuring your hands stay sanitized and refreshed.
Frequently Asked Questions (FAQs)
1. Is there such a thing as moisturizing hand sanitizer?
"Some common moisturizing ingredients in hand sanitizers are glycerin (it binds water), aloe vera (it soothes skin) and plant extracts (to condition skin)," Fu said. Luckily, this moisturizing sanitizer from Germ-X contains several hydrating ingredients like vitamin E and glycerin, and has a 62% ethyl alcohol formula.
2. What is the best hand sanitizer for dry hands?
Purell Advanced Hand Sanitizer Refreshing Gel Pump Bottle Purell is the No 1 hand sanitizer most trusted and used by hospitals, too, so you know you're getting something that works (on 99.99 percent of germs). It also contains skin conditioners to help keep moisture in.
3. Is moisturizing hand sanitizer good?
Shapiro recommends selecting a soap or sanitizer with an emollient and avoiding perfumes and dyes, as they can further irritate skin. Soaps and sanitizers with moisturizers can be just as effective, though Shapiro says hand sanitizers should have at least 60 percent alcohol.
4. Which sanitizer is best for dry skin?
Germ-X Moisturizing Original Hand Sanitizer Pros: The aloe vera formula contains vitamin E and aloe, which can help soothe and moisturize dry skin. It contains 63 percent ethyl alcohol. Cons: The original formula might be drying for some skin.
During our moisturizing hand sanitizer research, we found 24 moisturizing hand sanitizer products and shortlisted 10 quality products. We collected and analyzed 44,453 customer reviews through our big data system to write the moisturizing hand sanitizers list. We found that most customers choose moisturizing hand sanitizers with an average price of $20.34.
The moisturizing hand sanitizers are available for purchase. We have researched hundreds of brands and picked the top brands of moisturizing hand sanitizers, including Purell, Germ-X, Hempz, Dove, DERMAGLOVE. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.