Best Moisturizing Hand Sanitizers of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 9, 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Moisturizing hand sanitizers are a great way to keep hands clean and germ-free while also preventing dryness and irritation. These sanitizers contain moisturizing ingredients such as aloe vera, vitamin E, and glycerin, which help to hydrate and soothe the skin. Unlike traditional hand sanitizers that can leave hands feeling dry and rough, moisturizing hand sanitizers provide a more gentle and nourishing experience. They come in a variety of scents and sizes, making them a convenient option for on-the-go use. Overall, moisturizing hand sanitizers are a must-have for anyone looking to keep their hands clean and healthy.

At a Glance: Our Top Picks

Germ-X Advanced Hand Sanitizer 1L Cover #TOP 1
Germ-X Advanced Hand Sanitizer 1L
ftb score rating icon 9.8
The Honest Company Hand Sanitizer Spray Cover #TOP 2
The Honest Company Hand Sanitizer Spray
ftb score rating icon 9.7
Germ-X Advanced Hand Sanitizer Cover #TOP 3
Germ-X Advanced Hand Sanitizer
ftb score rating icon 9.5

Top 10 Moisturizing Hand Sanitizers

Germ-X Advanced Hand Sanitizer 1L

SUVELAM
Light Green
Germ-X Advanced Hand Sanitizer 1L Cover
Germ-X Advanced Hand Sanitizer with Aloe and Vitamin E, 1 Liter, Less Drying Moisturizing Gel, No Rinse Formula, Pump Bottle

Germ-X Advanced Hand Sanitizer with Aloe in 1 Liter size eliminates over 99.99% of germs in just 15 seconds. The advanced formula contains aloe and 70% alcohol, ensuring your hands are clean and moisturized. Made in the USA, this hand sanitizer is easy to use with its convenient pump.

What We Like
Eliminates over 99.99% of germs in 15 seconds
Contains aloe and 70% alcohol for effective cleaning and moisturizing
Easy to use with its convenient pump
Made in the USA
#TOP 2

The Honest Company Hand Sanitizer Spray

B07CL6X8SZ
Free & Clear
2 Fl Oz (Pack of 1)
The Honest Company Hand Sanitizer Spray Cover
The Honest Company Plant-Based Hand Sanitizer Spray, Kills 99.9% of Germs, Hypoallergenic, Quick-drying, Moisturizing, Fragrance-Free, 2 fl oz

The Honest Company Hand Sanitizer Spray, also known as Honest Hand Sanitizer Spray, is a plant-based hand sanitizer that effectively kills 99.9% of germs and bacteria. This hypoallergenic and dermatologist-tested spray is made with naturally-derived glycerin and aloe, leaving your skin feeling soft and moisturized. The quick-drying gel sanitizes your hands without leaving a sticky residue, making it convenient for everyday use. Suitable for ages 6 and up, this hand sanitizer is made without triclosan, parabens, synthetic fragrances, and benzalkonium chloride. The packaging may vary, but the great naturally-derived ingredients remain the same. Keep your hands clean and protected with The Honest Company Hand Sanitizer Spray.

What We Like
Effectively kills 99.9% of germs
Hypoallergenic and moisturizing
Quick-drying without sticky residue
#TOP 3

Germ-X Advanced Hand Sanitizer

YODED2796
Clear
Germ-X Advanced Hand Sanitizer Cover
Germ-X Advanced Hand Sanitizer, 34 Fl Oz (1 Liter), Less Drying Moisturizing Clear Gel, No Rinse Formula, Large Family Size Pump Bottle

Germ-X Advanced Hand Sanitizer is a must-have back-to-school essential for your family. With its fast and effective formula, it kills 99.99% of common germs in just 15 seconds, providing reliable protection at home, school, and in the classroom. The moisturizing formula leaves your hands feeling soft and refreshed, while the clear gel formula, enriched with moisturizers, ensures that your skin stays hydrated. This USP-grade 70% alcohol-based hand sanitizer is a convenient alternative to soap and water when they are not available. Germ-X offers a range of products, including pumps, flip-top caps, sprays, and wipes, so you can have confidence in fighting germs wherever you go. Made in the USA, Germ-X products have been trusted by families since 1997, providing high-quality sanitizers, wipes, and antibacterial hand soap at a great price.

What We Like
Fast and effective
Moisturizing formula
Convenient alternative to soap and water
#TOP 4

Amazon Basic Care Aloe Hand Sanitizer

Amazon Basic Care
Amazon Basic Care Aloe Hand Sanitizer Cover
Amazon Basic Care Hand Sanitizer with Aloe Vera, 62% Ethyl Alcohol, Vitamin E Enriched, 12 fl oz, Pack of 6

Amazon Basic Care Aloe Hand Sanitizer is an effective solution to eliminate more than 99.99% of many harmful germs and bacteria in as little as 15 seconds. This pack includes six 12-fluid ounce bottles of hand sanitizer, formulated with 62% Ethyl Alcohol, Vitamin E and Aloe. The product comes with a satisfaction guarantee, refundable for any reason within a year of purchase. It is a reliable Amazon brand that ensures quality and safety.

What We Like
Contains 62% Ethyl Alcohol that kills more than 99.99% of common germs and bacteria.
Includes six 12-fluid ounce bottles of hand sanitizer, providing a long-lasting solution to prevent the spread of germs.
Formulated with Vitamin E and Aloe, this hand sanitizer provides moisturization and nourishment to the skin.
#TOP 5

Purell Advanced Hand Sanitizer Refreshing Gel, 1L Bottle

9632-04-CMR
Clear
Purell Advanced Hand Sanitizer Refreshing Gel, 1L Bottle Cover
PURELL Advanced Hand Sanitizer Refreshing Gel, Clean Scent, 1 Liter Pump Bottle (Pack of 1) - 9632-04-CMR

Purell Advanced Hand Sanitizer Refreshing Gel is a convenient solution for sanitizing your hands when soap and water are not available. Its mild formula and moisturizers ensure that your hands stay soft even with frequent use. The 1-liter pump bottle is perfect for high-traffic areas like classrooms, offices, and events. It has a refreshing clean scent and evaporates quickly. It eliminates 99.99% of germs and is free of triclosan, parabens, phthalates, and preservatives, making it gentle on your skin.

What We Like
Eliminates 99.99% of germs on hands
Mild formula and moisturizers ensure soft hands with frequent use
Refreshing clean scent and quick evaporation for convenient sanitizing
#TOP 6

Germ-X Hand Sanitizer with Pump (Pack of 12)

Germ-X Hand Sanitizer with Pump (Pack of 12) Cover
Germ-X Original Hand Sanitizer, 8 Fl Oz (Pack of 12), Less Drying Moisturizing Gel with Vitamin E, No Rinse Formula, Pump Bottle

Germ-X Hand Sanitizer with Pump kills 99.99% of germs without water and eliminates many common harmful germs and bacteria in as little as 15 seconds. Its moisturizing formula with Vitamin E keeps your hand soft and healthy.

What We Like
Convenient pump design
Moisturizing formula with Vitamin E
Kills 99.99% of germs without water
#TOP 7

WipeEssentials Hand Sanitizer Wipes

F3988B6-AMZ
WipeEssentials Hand Sanitizer Wipes Cover
WipeEssentials Hand Sanitizer Hand Wipes for Adults and Kids - 90 wipes - 3 Packs of 30ct Hand Sanitizing Wipes, Travel Essentials

WipeEssentials Hand Wipes offer effective, long-lasting protection with their family-safe ingredient, Benzalkonium Chloride, ensuring you stay safe from germs after each use. With the added benefits of aloe vera and vitamin E, these wipes keep your skin soft and moisturized, making them perfect for both adults and kids. Unlike many sanitizing options, these wipes leave no soapy residue behind, providing a refreshing clean without any mess. Their convenient resealable packaging allows you to easily carry them in your purse or pocket, making them a must-have for your travels or daily routines.

What We Like
High-quality packaging
Effective sanitizing
Convenient travel size
Fresh fragrance
Good value for bulk buying
#TOP 8

Amazon Basics Hand Sanitizer - 67.6 fl oz, 62% Ethyl Alcohol

Amazon Basics
Amazon Basics Hand Sanitizer - 67.6 fl oz, 62% Ethyl Alcohol Cover
Amazon Basics Hand Sanitizer, Original Scent, Contains 62% Ethyl Alcohol, 67.60 Fl Oz (Pack of 1) (Previously Solimo

Amazon Basics Hand Sanitizer is a 67.6-fluid ounce bottle of 62% ethyl alcohol hand sanitizer that effectively kills more than 99.99% of common germs and bacteria in as little as 15 seconds. Its moisturizers leave hands feeling smooth, and it has an original scent. Voice shopping with Alexa is enabled, and satisfaction is guaranteed.

What We Like
Large 67.6-fluid ounce bottle
Effective at eliminating more than 99.99% of many harmful germs and bacteria in as little as 15 seconds
Moisturizers leave hands feeling smooth
#TOP 9

Purell Moisturizing Foam Hand Sanitizer Pack of 3

3002-06-EC
clear
Purell Moisturizing Foam Hand Sanitizer Pack of 3 Cover
Purell Advanced Hand Sanitizer 2in1 Moisturizing Foam, Naturally Fragranced with Essential Oils, 10 oz Pump Bottle (Pack of 3), 3002-06-EC

The Purell Advanced Hand Sanitizer 2in1 Moisturizing Foam is a luxurious foam formula that kills 99.99% of germs, while keeping hands healthy and soft. Its unique blend of hydrating ingredients improves skin health in just 5 days. This 10 oz foam pump bottle is perfect for home or office use, and leaves hands feeling clean with no sticky residue. It is free of harsh preservatives and does not contain dye, triclosan, parabens, or phthalates.

What We Like
Mess-free sanitizing
Improves skin health in just 5 days
Keeps hands healthy and soft with hydrating ingredients
Quick and easy way to refresh and keep hands clean throughout the day
Free of harsh preservatives, dye, triclosan, parabens, or phthalates
#TOP 10

Babyganics Foaming Pump Hand Sanitizer

4332406893
Babyganics Foaming Pump Hand Sanitizer Cover
BabyGanics Alcohol-Free Foaming Hand Sanitizer, Pump Bottle, Fragrance Free, 8.45 oz, 3 Pack

Babyganics Hand Sanitizer is an alcohol-free, fragrance-free foaming pump hand sanitizer that moisturizes your skin while effectively killing 99.9% of common bacteria. Made without harsh chemicals, such as parabens and sulfates, it is gentle and non-allergenic, making it suitable for all skin types. The plant-derived and thoughtfully chosen ingredients make it dermatologist tested and safe for regular use. This hand sanitizer provides the convenience of a foaming formula, leaving your hands clean, moisturized, and free from germs without the need for water.

What We Like
Alcohol-free
Moisturizing formula
Kills 99.9% bacteria
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is there such a thing as moisturizing hand sanitizer?

"Some common moisturizing ingredients in hand sanitizers are glycerin (it binds water), aloe vera (it soothes skin) and plant extracts (to condition skin)," Fu said. Luckily, this moisturizing sanitizer from Germ-X contains several hydrating ingredients like vitamin E and glycerin, and has a 62% ethyl alcohol formula.

2. What is the best hand sanitizer for dry hands?

Purell Advanced Hand Sanitizer Refreshing Gel Pump Bottle Purell is the No 1 hand sanitizer most trusted and used by hospitals, too, so you know you're getting something that works (on 99.99 percent of germs). It also contains skin conditioners to help keep moisture in.

3. Is moisturizing hand sanitizer good?

Shapiro recommends selecting a soap or sanitizer with an emollient and avoiding perfumes and dyes, as they can further irritate skin. Soaps and sanitizers with moisturizers can be just as effective, though Shapiro says hand sanitizers should have at least 60 percent alcohol.

4. Which sanitizer is best for dry skin?

Germ-X Moisturizing Original Hand Sanitizer Pros: The aloe vera formula contains vitamin E and aloe, which can help soothe and moisturize dry skin. It contains 63 percent ethyl alcohol. Cons: The original formula might be drying for some skin.

Editor's Notes

During our moisturizing hand sanitizer research, we found 24 moisturizing hand sanitizer products and shortlisted 10 quality products. We collected and analyzed 514,782 customer reviews through our big data system to write the moisturizing hand sanitizers list. We found that most customers choose moisturizing hand sanitizers with an average price of $16.08.

The moisturizing hand sanitizers are available for purchase. We have researched hundreds of brands and picked the top brands of moisturizing hand sanitizers, including Germ-X, The Honest Company, Purell, Diamond Wipes, Babyganics. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.