Best Hand Creams for Sensitive Skin of 2025

Aveeno Skin Relief Intense Moisture Hand Cream is a dermatologist-recommended non-greasy and fast-absorbing hand cream that locks in 24 hours of intense moisture, leaving your hands feeling soft and smooth. Formulated with soothing Prebiotic Oat, it helps heal dry skin and forms a protective barrier against the elements. This fragrance-free hand cream for sensitive skin is allergy tested and free of parabens and dyes. Use as needed to soothe and moisturize dry hands.

The ATTITUDE Hand Cream is designed specifically for sensitive skin, featuring clean and transparent ingredients verified by EWG. With 98.9% naturally sourced components, including oat extract, this cream helps to enhance your skin’s appearance while soothing dryness. Enriched with chamomile extract, it purifies and revitalizes your skin, making it a great choice for anyone looking to improve skin comfort. Dermatologically tested and vegan, this hand cream ensures you can care for your skin without compromising your values.

DERMA-E Hand Repair Cream is a nourishing and hydrating hand cream that deeply moisturizes dry or chapped skin. It is an unscented, cruelty-free lotion that is ideal for sensitive skin, reducing skin redness. The all-natural formula contains Aloe Vera Extract to soothe and comfort irritated skin, Shea Butter to deeply moisturize, Vitamin E to help protect, Provitamin B5 to deeply hydrate, and Pycnogenol to improve elasticity. This daily skin care cream absorbs quickly into the skin, leaving your hands soft and smooth. Apply it to your entire hand and wrist as needed for best results. DERMA-E Hand Repair Cream is a clean beauty product that is 100% vegan and eco-ethical, containing no parabens, sulfates, mineral oil, petrolatum, lanolin, gluten, soy, or GMOs, and is supplied in recyclable packaging.

Do you suffer from dry, chapped, or cracked hands? Try CeraVe Therapeutic Hand Cream, developed with dermatologists. This non-greasy and fast-absorbing cream is formulated with hyaluronic acid to retain your skin's natural moisture, niacinamide to calm your skin, and ceramides to restore and maintain your skin's natural barrier. It is accepted by the National Eczema Association and perfect for over-washed or overworked hands. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) and are suitable for dry, sensitive, oily, and acne-prone skin.

The Hempz Hand Cream is designed for those struggling with dry or sensitive skin. This cream uses 100% hemp seed oil, providing intense hydration and nourishment. With ingredients like sunflower seed oil and shea butter, it helps maintain a moisture barrier and gives your skin a healthy glow. Additionally, it contains antioxidants such as vitamins A, C, E, and ginger root extract to combat dryness and protect your skin from environmental stressors. This cruelty-free and vegan formula ensures you can care for your hands while being kind to the planet.

The Body Shop Almond Milk & Honey Hand Cream is a perfect, on-the-go solution to soothe and protect dry hands. This hand cream is specially formulated with quality ingredients, such as organic almond milk and honey. It is dermatologically tested, hypoallergenic, and kind to sensitive skin. The hydrating and skin-loving properties of almond milk and almond oil help to give your skin a natural glow. The Body Shop is a 100% vegetarian brand that has been against animal testing since 1976.

O'Keeffe's Working Hands Hand Cream is a hardworking skincare that provides guaranteed relief for extremely dry, cracked hands. It creates a protective layer on the skin's surface that locks in moisture and keeps your skin hydrated. This extra strong hand cream is suitable for people with sensitive skin, including those with Diabetes. Apply after hand washing, after bathing, and at bedtime for the best results, and a small amount of product is needed.

Treat your sensitive hands with the Weleda Soothing Sensitive Skin Almond Hand Cream. This vegan cream is perfect for those with easily irritated skin. It is quickly absorbed and strengthens the skin's own protective layer, reducing tightness and moisturizing your hands. The cream is free from synthetic preservatives, fragrances, colorants, and raw materials derived from mineral oil, making it safe for your skin. Certified natural per NATRUE standards, this hand cream is a must-have for those with sensitive skin.

O'Keeffe's Hand Cream is designed to provide intense relief for extremely dry and cracked hands. This highly concentrated formula creates a protective barrier on your skin, locking in moisture to keep your hands hydrated throughout the day. When used regularly, you'll notice a significant improvement in your skin's texture and softness in just a few days. For optimal results, apply the cream after washing your hands, bathing, or before bedtime. It is also suitable for sensitive skin, making it a great choice for everyone, including those with diabetes.

This Works Hand Cream is a nourishing solution designed for dry and sensitive skin. Infused with Shea Butter and Vitamin E, it provides quick and lasting relief from dryness, making your hands feel soft and hydrated. The unique Bio Boost formula, rich in plant oils, helps protect your skin from environmental stressors while maintaining its natural barrier. The calming fragrance, derived from Ylang Ylang, Lavender, and Neroli essential oils, allows you to unwind during your daily routine, whether you’re in the shower or simply washing your hands.