Best Hand Creams for Eczema of 2026

Lisa Bechard Avatar
Lisa Bechard
Last Updated: Jan 21, 2026

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Hand creams for eczema are specially formulated to soothe and hydrate dry, itchy, and irritated skin. These creams contain ingredients like shea butter, colloidal oatmeal, and ceramides that help to repair and strengthen the skin's natural barrier. They are free of harsh chemicals and fragrances that can irritate sensitive skin and are suitable for people with eczema or other skin conditions. Some popular hand creams for eczema include CeraVe Therapeutic Hand Cream, Eucerin Eczema Relief Hand Cream, and Aveeno Eczema Therapy Hand Cream. These creams provide long-lasting moisture and relief from eczema symptoms, leaving hands soft, smooth, and healthy-looking.

At a Glance: Our Top Picks

Skinfix Hand Relief Cream Cover #TOP 1
Skinfix Hand Relief Cream
ftb score rating icon 9.9
Gloves In A Bottle Silicone Barrier Hand Lotion 2 oz Cover #TOP 2
Gloves In A Bottle Silicone Barrier Hand Lotion 2 oz
ftb score rating icon 9.8
La Roche-Posay Cicaplast Hand Cream Cover #TOP 3
La Roche-Posay Cicaplast Hand Cream
ftb score rating icon 9.6

Top 10 Hand Creams for Eczema

#TOP 1

Skinfix Hand Relief Cream

Skinfix
000458F-01
Multi
3 Fl Oz (Pack of 1)
Skinfix Hand Relief Cream Cover
Skinfix Hand Relief Cream - 3 fl oz - Reduces Visible Redness, Stinging & Cracking for Dry, Sensitive Skin - Accepted by the National Eczema Association - Fragrance Free - Vegan, Cruelty Free

Skinfix Hand Relief is designed to soothe and protect dry, sensitive, and eczema-prone skin. It uses colloidal oatmeal to help calm irritation and reduce redness, making your hands feel comforted and less itchy. The cream provides a noticeable increase in hydration quickly, so your skin feels softer and more nourished. It also contains a special triple lipid complex that helps lock in moisture by mimicking your skin's natural barrier. This means your hands stay hydrated longer and are protected from dryness and cracking. You can apply this non-greasy cream whenever your hands need extra care, especially after washing.

What We Like
Soothes irritation and redness
Boosts hydration quickly
Protects skin barrier
Non-greasy formula
#TOP 2

Gloves In A Bottle Silicone Barrier Hand Lotion 2 oz

20995
2 oz
2 Ounce (Pack of 1)
Gloves In A Bottle Silicone Barrier Hand Lotion 2 oz Cover
Gloves In A Bottle Hand Lotion for Nurses – Best Travel Hand Cream for Dry, Cracked Hands, Eczema & Psoriasis Relief – Silicone Glove Hand Lotion for Healthcare Workers – 2 oz

Gloves In A Bottle Hand Lotion is specially designed for healthcare workers who need reliable hand protection. It forms a unique silicone barrier that locks in moisture and shields your skin from frequent washing, sanitizers, and harsh chemicals, keeping your hands healthy during long shifts. Its travel-friendly size makes it easy to carry wherever you go, so you can hydrate your hands anytime. The lotion absorbs quickly without greasiness or fragrance, making it gentle and suitable for sensitive skin, including eczema sufferers. Plus, it deeply nourishes dry, cracked hands, helping to soothe and repair skin damaged by conditions like eczema and psoriasis.

What We Like
Silicone moisture barrier
Travel-friendly size
Fast-absorbing, non-greasy
Soothes eczema and psoriasis

La Roche-Posay Cicaplast Hand Cream

3337872414145
La Roche-Posay Cicaplast Hand Cream Cover
La Roche-Posay Cicaplast Hand Cream, Instant Relief Moisturizing Hand Lotion for Dry Hands, Shea Butter Lotion for Dry Cracked Hands, Non Greasy, Fragrance Free, 1.69 Fl Oz (Pack of 1)

La Roche-Posay Cicaplast Hand Cream is the perfect solution for dry and rough hands. This shea butter lotion is fast-absorbing, non-greasy, and immediately soothes damaged and dry to very dry hands. It provides up to 48-hour hydration for hands that are damaged by cold weather and frequent hand-washing. It is also recommended for hands exposed to chemicals, rough cracked hands, and hands damaged by aggressions at home and work. The National Eczema Association has accepted this product.

What We Like
Moisturizes effectively
Quick absorption
Non-greasy finish
Long-lasting hydration
Good for sensitive skin
#TOP 4

Gloves In A Bottle Shielding Lotion

80995
8 oz
8 Ounce (Pack of 1)
Gloves In A Bottle Shielding Lotion Cover
Gloves In A Bottle Shielding Lotion, Relief for Eczema and Psoriasis, 8 Fl Oz (Pack of 1)

Gloves In A Bottle Lotion creates a protective layer on your skin, acting like invisible gloves that shield your hands, arms, neck, legs, feet, and face from dryness. This barrier helps keep out irritants that can strip moisture, allowing your skin to hold onto its natural oils. With just one use, the lotion provides lasting protection for four hours or more, giving you long-lasting comfort without frequent reapplication. It also helps restore the skin’s natural defense, which can be weakened by everyday activities, so your skin stays healthy and well-moisturized throughout the day.

What We Like
Long-lasting moisture protection
Invisible skin shield
Prevents moisture loss
Restores skin’s natural barrier
#TOP 5

Gloves In A Bottle Psoriasis Eczema Relief Hand Lotion 3.4 oz

GIABTUBE
Regular
Gloves In A Bottle Psoriasis Eczema Relief Hand Lotion 3.4 oz Cover
Gloves In A Bottle Psoriasis Eczema Relief Hand Lotion Travel Size - Shielding Lotion for Women, Men, 6 months old or older babies - Cracked Hands Repair Cream - 3.4 oz

The Gloves In A Bottle Hand Lotion is designed to deeply moisturize and repair dry, irritated skin caused by harsh weather, soaps, and conditions like eczema and psoriasis. It helps restore your skin’s natural barrier, allowing it to heal from the inside out. This lotion offers long-lasting hydration that stays effective for 4 to 12 hours without washing off, keeping your hands protected throughout the day. Additionally, it shields your skin from environmental toxins, frequent hand washing, and irritants found in many cleaning and cosmetic products, making it ideal if you have sensitive skin or are prone to allergies or rashes.

What We Like
Long-lasting hydration
Restores skin barrier
Protects against irritants
Soothes eczema and psoriasis
Non-greasy, fast absorbing

CeraVe Therapeutic Hand Cream for Dry Hands

usa-iiu-tm269
WHITE
3 Ounce (Pack of 1)
CeraVe Therapeutic Hand Cream for Dry Hands Cover
CeraVe Therapeutic Hand Cream for Dry Cracked Hands With Hyaluronic Acid and Niacinamide, Fragrance Free 3 Ounce

Do you suffer from dry, chapped, or cracked hands? Try CeraVe Therapeutic Hand Cream, developed with dermatologists. This non-greasy and fast-absorbing cream is formulated with hyaluronic acid to retain your skin's natural moisture, niacinamide to calm your skin, and ceramides to restore and maintain your skin's natural barrier. It is accepted by the National Eczema Association and perfect for over-washed or overworked hands. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) and are suitable for dry, sensitive, oily, and acne-prone skin.

What We Like
Quick absorption
Non-greasy formula
Effective for dry, cracked hands
Long-lasting hydration
Fragrance-free
#TOP 7

Dr Hess Hand Cream

00283
2 Ounce (Pack of 1)
Dr Hess Hand Cream Cover
Dr. Hess Genuine Hand Cream, Nourishing & Softening Lotion for Dry, Cracked Hands & Heels, Eczema Relief, with Lanolin, Beeswax, Olive Oil & Vitamin E, Cruelty-Free, Paraben & Sulfate-Free, 2 oz

Dr Hess Nourishing Hand Cream is a highly effective solution for dry, cracked hands and skin. This hand cream is formulated with key ingredients like lanolin, beeswax, olive oil, and vitamin E to lock in moisture, hydrate, soothe, and protect your hands. It is perfect for those with eczema, minor abrasions, burns, and chafing. The cruelty-free, paraben-free, and sulfate-free formula ensures that it is safe and gentle on your skin. The travel-friendly size makes it convenient to carry with you wherever you go. Not only does it work wonders on your hands, but it also provides intense healing and nourishment for dry heels, elbows, and other areas in need of hydration. Dr Hess Nourishing Hand Cream is suitable for both men and women, leaving your hands soft, smooth, and rejuvenated.

What We Like
Intense Healing and Nourishment
Cruelty-Free and Safe Formula
Travel-Friendly and Versatile
#TOP 8

Gloves In A Bottle Shielding Lotion 8 oz

giab-8oz-pump-box
Gloves In A Bottle Shielding Lotion 8 oz Cover
Gloves In A Bottle Shielding Lotion – Non-Greasy, Hypoallergenic Cream for Eczema & Cracked Hands, Unscented Lotion for Men, Women & Babies 6 Months+, Works Great on All Skin | 8 Oz with New Pump

Gloves In A Bottle Lotion offers trusted care for dry, cracked, and eczema-prone skin, providing quick relief and moisture restoration. With over 30 years of dermatological trust and millions sold, this lotion comes in an easy-to-use 8 oz bottle with a convenient pump for smooth application. It delivers long-lasting hydration that resists water for up to 12 hours, so your hands stay soft even after multiple washes. The non-greasy, fast-absorbing formula makes it perfect for busy professionals and parents who need effective, everyday hand care at home, work, or on the go.

What We Like
Trusted dermatological formula
Easy pump dispenser
Long-lasting hydration
Non-greasy, fast-absorbing

Ora's Amazing Herbal Ultra Healing Body Butter

2 Ounce (Pack of 1)
Ora's Amazing Herbal Ultra Healing Body Butter Cover
Ultra Healing Body Butter, Cream for Eczema and Dry Skin, Fragrance Free Body Butter, Hand Cream for Dry Cracked Hands, Unscented Hand Cream, Skin Repair Cream, 2 Oz Travel Size, Made in the USA

Ora's Healing Body Butter is a rich, concentrated formula that provides deep moisture and nourishment for your skin. Made with organic shea butter and an herbal-infused base oil, it effectively hydrates dry areas like elbows, knees, and cracked heels. Although it is fragrance-free, you can still enjoy the natural, light aroma of the ingredients. This body butter is free from harmful additives like parabens and gluten, making it a safe choice for sensitive skin. It's also packed with essential nutrients that help soothe itchy skin and prevent stretch marks, ensuring your skin looks and feels its best.

What We Like
Deeply moisturizing
Natural ingredients
Fragrance-free
Safe for sensitive skin

Nécessaire Hand Cream with Ceramides

2709442
Nécessaire Hand Cream with Ceramides Cover
Nécessaire - The Hand Cream for Women & Men with 5 Ceramides & Peptides, Fragrance-Free Hand Lotion, Fast-Absorbing, Non-Greasy. - 2.2 fl oz.

Nécessaire Hand Cream offers a comprehensive solution for maintaining healthy hands. Formulated with five ceramides and peptides, this cream helps to heal and restore moisture, ensuring your skin feels soft and supple. The inclusion of niacinamide and marula oil enhances its effectiveness in treating dryness and brittle cuticles. Additionally, the cream is dermatologist-tested and hypoallergenic, making it suitable for sensitive skin. With a commitment to sustainability, the packaging is eco-friendly, so you can care for your hands while being kind to the planet.

What We Like
Hydrating and healing properties
Suitable for sensitive skin
Eco-friendly packaging
Fast-absorbing formula
Buying Guide Image
Editor's Notes

During our hand cream for eczema research, we found 48 hand cream for eczema products and shortlisted 10 quality products. We collected and analyzed 200,261 customer reviews through our big data system to write the hand creams for eczema list. We found that most customers choose hand creams for eczema with an average price of $17.18.

The hand creams for eczema are available for purchase. We have researched hundreds of brands and picked the top brands of hand creams for eczema, including Skinfix, Gloves In A Bottle, La Roche-Posay, CeraVe, Dr. Hess. The seller of top 1 product has received honest feedback from 8,071 consumers with an average rating of 4.9.

Written by
Lisa Bechard Avatar

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.