Best Hand Creams for Dry Skin of 2025

O'Keeffe's Working Hands Hand Cream is a hardworking skincare that provides guaranteed relief for extremely dry, cracked hands. It creates a protective layer on the skin's surface that locks in moisture and keeps your skin hydrated. This extra strong hand cream is suitable for people with sensitive skin, including those with Diabetes. Apply after hand washing, after bathing, and at bedtime for the best results, and a small amount of product is needed.

La Roche-Posay Cicaplast Hand Cream is the perfect solution for dry and rough hands. This shea butter lotion is fast-absorbing, non-greasy, and immediately soothes damaged and dry to very dry hands. It provides up to 48-hour hydration for hands that are damaged by cold weather and frequent hand-washing. It is also recommended for hands exposed to chemicals, rough cracked hands, and hands damaged by aggressions at home and work. The National Eczema Association has accepted this product.

Do you suffer from dry, chapped, or cracked hands? Try CeraVe Therapeutic Hand Cream, developed with dermatologists. This non-greasy and fast-absorbing cream is formulated with hyaluronic acid to retain your skin's natural moisture, niacinamide to calm your skin, and ceramides to restore and maintain your skin's natural barrier. It is accepted by the National Eczema Association and perfect for over-washed or overworked hands. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) and are suitable for dry, sensitive, oily, and acne-prone skin.

Curél Extreme Dry Hand Relief is a dermatologist recommended pocket-sized hand cream that provides long-lasting relief for extremely dry hands. Formulated with eucalyptus extract, Vitamin E, and Monoi Oil, this non-greasy hand cream is quickly absorbed and protects skin from dryness up to 24 hours and through multiple hand washes. It repairs skin's moisture to help prevent dryness and provides relief from everyday dryness caused by hand sanitizer usage. This on-the-go hand cream is perfect for essential employees to deeply moisturize rough hands, even during extended shifts.

O'Keeffe's Working Hands Hand Cream is a concentrated cream that creates a protective layer on the skin's surface and locks in moisture, providing guaranteed relief for extremely dry, cracked hands. For best results, apply after hand washing, bathing, and at bedtime. It is hypoallergenic, safe for people with diabetes, unscented, and non-greasy. The 3.4-ounce jar is an ideal size for travel.

O'Keeffe's Hand Cream is designed to provide intense relief for extremely dry and cracked hands. This highly concentrated formula creates a protective barrier on your skin, locking in moisture to keep your hands hydrated throughout the day. When used regularly, you'll notice a significant improvement in your skin's texture and softness in just a few days. For optimal results, apply the cream after washing your hands, bathing, or before bedtime. It is also suitable for sensitive skin, making it a great choice for everyone, including those with diabetes.

Eucerin Advanced Repair Hand Cream is a fast-absorbing, non-greasy formula that helps to repair dry, rough skin on the hands. It is enriched with buffered Alpha Hydroxy, Ceramide-3 and Natural Moisturizing Factors, and is fragrance free and dye free. Customers have praised its ability to keep their hands smooth and soft, even after frequent washing and exposure to harsh elements. It is perfect for on-the-go use, and comes in a convenient travel size tube.

Gold Bond Ultimate Healing Hand Cream is a 3-oz. tube of nourishing moisture that contains 7 intensive moisturizers, plus vitamins A, C and E. It repairs dry, problem hands, even after washing your hands, and is hypoallergenic and fragrance free. Customers love it for its quick absorption and effectiveness, even for those with sensitive skin.

Aveeno Skin Relief Intense Moisture Hand Cream is a dermatologist-recommended non-greasy and fast-absorbing hand cream that locks in 24 hours of intense moisture, leaving your hands feeling soft and smooth. Formulated with soothing Prebiotic Oat, it helps heal dry skin and forms a protective barrier against the elements. This fragrance-free hand cream for sensitive skin is allergy tested and free of parabens and dyes. Use as needed to soothe and moisturize dry hands.

The Yoken Hand Cream Set is designed to nourish and rejuvenate your dry hands with its rich formula, which includes 20% shea butter along with jojoba oil, sweet almond, and honey extracts. This hand cream is perfect for daily use, helping to protect your skin from environmental stressors while maintaining a balanced barrier. The set features six delightful floral and plant fragrances, allowing you to enjoy a different scent each day. Packaged beautifully in a tin, it makes for a thoughtful gift for any occasion, from holidays to birthdays.