Best Decongestant Sprays of 2025

"During allergy season, I find this spray really helps. My husband has started using it too."

"I used to struggle with breathing normally. After using Nasacort, one squirt at night and all my problems are gone. It's amazing!"

"I've been using this product for over 10 years. It's simply fabulous."

"I've always disliked nasal sprays, relying on pills. However, I decided to give this a shot and I CAN'T DENY THAT IT WORKS EXTREMELY WELL. I rate it a 5 for effectiveness and a 5 for no drip, but a 3 for the Vicks vapor effect. Just a tip: avoid using it before meals as it affects your taste and smell for a couple of hours."

"I was thrilled to discover this Berkley Jensen brand after searching for alternatives to Afrin. The price is unbeatable—two bottles for $10—and it works just as well. No smell, no drip, no burn. I’m really happy with my purchase and recommend stocking up!"

"I initially bought this at BJ's and was delighted to find it on Amazon. It has identical ingredients to Vicks but at a much better price. Two bigger bottles for $9.99 is a steal, and it works wonderfully. I'm a satisfied customer!"

"I get almost immediate relief from a stuffed-up nose. Just a word of caution: using it too often might lead to dependency, which means I'd have to stop using it for a while."

"I've relied on Neo-synephrine since childhood for allergies and colds. It's hard to find in drops, so I refill my recycled dropper bottles. It's great to have something that helps me breathe."

"I absolutely love and trust this product. It works like a charm! It was hard to find locally, but I'm thrilled I finally found it on Amazon."

"It's no longer available in my usual store, but I love using Amazon. I can order it whenever I need and it'll be in stock."

"I love how gentle it is on my nasal lining and keeps my tissues moisturized. I don’t wake up with nasal congestion anymore, and it's great for my husband's nose bleeds!"

"I was surprised by how enjoyable this product is! It arrived safely sealed and has a subtle floral scent that doesn’t bother me at all. The gel sticks well inside my nostrils and keeps me comfortable during the dry winter months!"

"I bought this for minor nose bleeds caused by dry air. While it keeps my nose moist, I do find it sometimes leaves an uncomfortable residue when it dries, and the scent is a bit sweet for my taste."

"After trying many saline sprays, I finally found one that doesn't leak and delivers a direct spray into my nostril. It actually helps with my nasal issues, so I'm convinced this is the brand I'll stick with from now on!"

"I’ve followed the directions on the can, and I can really feel the results! It's been a great addition to my routine."

"I was hoping for a product that would be as effective as medicated nasal sprays, but this one doesn’t quite measure up in my opinion. I was also looking forward to a Vicks minty fresh scent, but was disappointed to find it has no scent at all."

"I've tried nearly every nasal spray, but Vicks 4way is, without a doubt, the best I've ever used. It clears my head quickly and lasts almost the entire day. Totally worth it!"

"I've relied on this spray for years! No matter how many different and expensive options I try, I always return to this one. It's frustrating that I can't find it in stores anymore because it’s such a great product. Just one spray in each nostril clears me up instantly!"

"Living in south Texas, I deal with allergies from grass, ragweed, and Cedar Fever. This spray is my go-to for surviving those tough days!"

"I tried steroids without any success; they just don’t work for me. I created a small spacer that allows the plunger to only depress about 25% of its stroke, which opens me up at bedtime without burning my nose. I only need this once a day at bedtime with no significant discomfort or rebound congestion. I look forward to a more effective product from pharma one day!"

"Honestly, this is the best nasal spray I’ve ever used. It clears my congestion immediately and keeps me clear for hours—better than prescription options. The only downside is that some bottles have leaked during transit."

"I’ve been using this product for over 20 years and find it to be the most gentle and effective option out there. I really hope they never stop making it!"

"I find this product essential for my baby when he gets congested at night. The mist is so gentle yet effective, making it easy to help him breathe better. It has really improved his sleep quality!"

"Putting this together was a breeze! I love that it lasts for 1.5 hours and works perfectly for quick treatments. This should definitely be a staple in every home with a newborn."

"My daughter is not a fan of getting her nose cleaned, but this product makes it possible to help her breathe easier even while she’s sleeping. It’s really been a lifesaver!"

"I find Boogie Wipes Saline Drops to be a game-changer for my little one's nose. The gentle saline solution loosens stubborn mucus quickly, helping my baby breathe comfortably. It’s safe and free of harsh chemicals, which is reassuring for regular use. The dropper design makes it easy and mess-free to apply. Now, it's a must-have in our diaper bag during cold and allergy seasons!"

"This product is amazing! I use just two drops in each nostril, and it clears my baby right up. I highly recommend it for infants!"

"My baby's doctor suggested these saline drops for her cold, and I'm so glad! They're super easy to use—just drops into the nose, no spraying or pressure involved. It does exactly what it's supposed to!"

"I love how easy this product is to use! Just turn right for mist and left to turn off. It’s sensory friendly, and my toddler enjoys it. The mist isn’t too strong but still effective."

"As a respiratory therapist, I think this product is a must-have for newborns. It produces a fine mist like a nebulizer, which is incredibly handy for my newborn's stuffy nose and dry airways. It's a genius, hospital-grade creation!"

"My toddler refuses anything in her nose, but this has been a life saver! I use it while she sleeps, and it works like magic."