Best Joint & Muscle Pain Relief Rubs of 2025

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Joint and muscle pain can be debilitating, making it difficult to perform daily tasks and enjoy life. Fortunately, there are a variety of pain relief rubs on the market that can help alleviate discomfort. These rubs are designed to provide targeted relief to the affected area, penetrating deep into the skin to soothe sore muscles and joints. They contain a blend of natural ingredients such as menthol, camphor, and eucalyptus oil that work together to provide a cooling and warming sensation, reducing inflammation and increasing blood flow to the affected area. These pain relief rubs are a great alternative to oral pain medication and can be used as needed throughout the day.
At a Glance: Our Top Picks
Top 10 Joint & Muscle Pain Relief Rubs
Penetrex Joint & Muscle Therapy - 2oz Cream
The Penetrex Joint & Muscle Therapy cream is a premium formula that provides relief for back, neck, hands, feet, and more. It can be used on its own or in conjunction with complementary therapies like heating pads, ice packs, massagers, and supplements. This cream uses a revolutionary delivery system to deliver unique ingredients like Arnica, Glucosamine, MSM, Choline, Boswellia Serrata & Vitamin B6 that provide targeted soothing benefits to the affected area(s). The cream has a vanishing scent, is non-greasy, non-staining, paraben-free, and never tested on animals. Additionally, it comes with a happiness pledge, so you can try the product without worry.
Biofreeze Menthol Gel: Fast Relief for Muscle and Joint Pain
If you're struggling with muscle or joint pain, Biofreeze Menthol Gel is the solution you've been looking for. This clinically-recommended brand is trusted by healthcare professionals such as physical therapists, pharmacists, and athletic trainers. The gel's 3 fl oz tube is perfect for treating small and large muscle areas. Whether you're dealing with sore muscles, arthritis, backaches, strains, bruises, sprains, or joint pain, Biofreeze can provide fast and effective relief. The product is cruelty-free and made with USP grade menthol, free of NSAIDs. It is also FSA/HSA eligible, meaning you can save up to 30%.
Bengay Ultra Strength Topical Pain Relief Cream
Get ultra-strong relief from minor arthritis, muscle, joint, and back pain with Bengay Ultra Strength Topical Pain Relief Cream. The non-greasy formula contains three pain-relieving ingredients—camphor, menthol, and methyl salicylate—for deep and penetrating pain relief. The cream comes in a convenient tube for on-the-go pain relief, and it contains more pain-relieving ingredients than any other Bengay product. Bengay is a physician-recommended OTC topical analgesic, making it a reliable choice for those in need of pain relief.
Aspercreme Max Strength Pain Relief Liquid
Aspercreme Pain Relief Liquid offers maximum strength relief for muscle, joint, and back pain. This fast-acting formula quickly numbs discomfort, providing you with effective pain management when you need it most. Its odor-free composition ensures that you can use it discreetly without worrying about strong smells. Plus, the convenient roll-on applicator keeps your hands clean and free from greasy residue, making it easy to apply wherever you are. Whether at home or on the go, this product is designed to enhance your comfort and well-being.
Blue Emu Muscle and Joint Cream
The Blue Emu Muscle and Joint Cream is a top-rated emu oil formula that offers daily soothing assistance for your tired joints and muscles. With natural botanical extracts, Aloe Vera, MSM, and Glucosamine, the cream penetrates deep into your skin for maximum relief. Unlike other creams, it is odor-free, non-greasy, and irritation-free. Daily use is recommended, and the cream can be applied to multiple areas of the body, including back, neck, shoulders, elbows, wrists, knees, hips, feet, hands, and ankles. Also, it can help dry, chapped, or weathered skin. Made in the USA, the cream is FSA/HSA eligible.
Aspercreme with Lidocaine Pain Relief Cream, 4.3 Oz
Aspercreme with Lidocaine Pain Relief Cream is a topical numbing cream that targets more pain receptors to quickly and effectively relieve minor pains for hours. It contains 4% lidocaine which makes it a fast-acting pain reliever that penetrates muscles and joints with no irritation or burning.
Blue Stop Max Massage Gel and Muscle Rub
Blue Stop Max Massage Gel and Muscle Rub is a 16 Oz pump bottle that provides muscle, joint, and body ache relief. Made with 100% organic Aloe Vera and safe ingredients, it targets problem points to provide relief where it's needed most. It has a peachy fresh and silky smooth texture, leaving no harsh scent on the skin. It is safe for everyday use and is effective before bed, before and after workouts, or for general daily application.
Advil Targeted Relief Pain Cream
Advil Pain Relief Cream offers targeted relief for various types of pain, including arthritis, joint, and muscle discomfort. This cream features a unique blend of four powerful ingredients that work together to address pain effectively. You will appreciate the warming and cooling sensations that provide immediate comfort, lasting up to eight hours. Its easy application ensures that it glides smoothly on your skin without leaving a greasy residue. This makes it a convenient choice for quick relief, especially for those long study sessions or active days.
Biofreeze Roll-On Pain-Relieving Gel for Muscles and Joints
Biofreeze Roll-On Pain-Relieving Gel is a clinically recommended topical pain reliever that provides long-lasting pain relief to sore muscles and joints. The cooling menthol formula is fast-acting, and the 3 fl oz roll-on offers hands-free application via roller ball, making it easy to use without making a mess. It is TSA-friendly, making it suitable for travel and on-the-go, and is trusted by healthcare professionals such as pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers.
Sombra Warm Pain Relief Gel 4oz
Sombra Warm Relief Gel has been trusted for over 50 years, making it a reliable choice for pain relief. This gel is perfect for easing muscle soreness and joint discomfort, whether you're dealing with arthritis or just need some pre-workout tension relief. With its premium plant-derived ingredients, including warming camphor and cooling menthol, you can enjoy a soothing experience without artificial additives. It's also recommended by doctors and widely available, providing you with clinical-quality relief right at home. This gel is ideal for athletes, hobbyists, and seniors alike, helping you get back to your favorite activities pain-free.
Frequently Asked Questions (FAQs)
1. What vitamin helps with joint pain?
Vitamin D is known to help with joint pain. Studies have shown that individuals with rheumatoid arthritis often have low levels of vitamin D. Supplementing with vitamin D can potentially improve arthritis treatment and alleviate chronic pain.
2. What is the fastest way to reduce joint inflammation?
The fastest way to reduce joint inflammation is through the RICE method. RICE stands for rest, ice, compression, and elevation. This method is particularly effective for reducing pain and swelling caused by sudden injuries. If the pain and swelling do not improve after using the RICE method, it is advisable to seek medical attention from an orthopedist.
During our joint & muscle pain relief rub research, we found 24 joint & muscle pain relief rub products and shortlisted 10 quality products. We collected and analyzed 912,778 customer reviews through our big data system to write the joint & muscle pain relief rubs list. We found that most customers choose joint & muscle pain relief rubs with an average price of $14.61.
The joint & muscle pain relief rubs are available for purchase. We have researched hundreds of brands and picked the top brands of joint & muscle pain relief rubs, including Penetrex, Biofreeze, Bengay, Aspercreme, Blue Emu. The seller of top 1 product has received honest feedback from 1,744 consumers with an average rating of 4.9.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.
Joint & Muscle Pain Relief Rubs Comparison Table
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Brand | Penetrex | Biofreeze | Bengay | Aspercreme | Blue Emu | Aspercreme | Blue Stop Max | Advil | Biofreeze | Sombra |
Special Feature | Non staining | Clinically Proven, Targeted, Long-Lasting, Fast-Acting | Soothing | Fast Acting | - | Fast Acting | - | Targeted, Fast Acting | Targeted, Long-Lasting, No Animal Testing, Fast-Acting | - |
Item Weight | 2 Ounces | 0.19 Pounds | 4.8 Ounces | 2.6 Ounces | - | 4.3 Ounces | - | 3.18 Ounces | 3 Ounces | - |
Item dimensions L x W x H | 2.6 x 2.6 x 4.5 inches | 1 x 2 x 1 inches | 1.75 x 7 x 4 inches | 3.11 x 1.61 x 5.9 inches | - | 2.95 x 1.75 x 6 inches | - | 1.7 x 2.6 x 5.9 inches | 1 x 2 x 1 inches | - |
Product Benefits | Muscle Therapy | Alcohol-Free | Arthritis Control | Body Pain Relief | - | Back Pain Relief, Body Pain Relief, Arthritis Control | - | Pain Relief | Back Pain Relief, Body Pain Relief, Pain Relief | - |
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