Best Hydroxyapatite Toothpaste of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 11, 2026

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Hydroxyapatite toothpaste is a popular dental product that is gaining popularity in the United States. It is a natural mineral that is found in our teeth and bones, and it has been found to have numerous benefits for oral health. Hydroxyapatite toothpaste is known to help strengthen and remineralize tooth enamel, which can help prevent tooth decay and cavities. It is also effective in reducing tooth sensitivity and improving overall oral hygiene. With its natural composition and proven benefits, hydroxyapatite toothpaste is a great choice for anyone looking to improve their oral health.

At a Glance: Our Top Picks

Boka Ela Mint Toothpaste with Nano-Hydroxyapatite and Aloe Vera Cover #TOP 1
Boka Ela Mint Toothpaste with Nano-Hydroxyapatite and Aloe Vera
ftb score rating icon 9.9
CHOMP Very Berry Toothpaste Tablets Refill Cover #TOP 2
CHOMP Very Berry Toothpaste Tablets Refill
ftb score rating icon 9.8
Mouthology Nano Hydroxyapatite Toothpaste Cover #TOP 3
Mouthology Nano Hydroxyapatite Toothpaste
ftb score rating icon 9.6

Top 9 Hydroxyapatite Toothpaste

Boka Ela Mint Toothpaste with Nano-Hydroxyapatite and Aloe Vera

BOK-FGS-P007-01-AB1US
No Color
4 Ounce (Pack of 1)
Boka Ela Mint Toothpaste with Nano-Hydroxyapatite and Aloe Vera Cover
Boka Fluoride Free Toothpaste, Nano Hydroxyapatite Toothpaste, Appropriate for Sensitive Teeth - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured

The Boka Ela Mint Toothpaste is a natural toothpaste made in the USA that uses Nano Hydroxyapatite (n-HA) to remineralize teeth and reduce sensitivity. This toothpaste is free from fluoride, sulfates, parabens, and artificial flavors and colors, making it non-toxic and 100% biocompatible. It also uses aloe vera, xylitol, green tea, and mint to provide a refreshing and invigorating flavor profile. Boka believes that oral care is the foundation of health, and this toothpaste is designed to heal your mouth and nourish your body.

What We Like
Enamel strengthening
Reduces tooth sensitivity
Natural, fluoride-free formula
Gentle, non-gritty texture
Pleasant, mild flavors
#TOP 2

CHOMP Very Berry Toothpaste Tablets Refill

CHOMP
CMP-TPN-VB-AD-R1
CHOMP Very Berry Toothpaste Tablets Refill Cover
Chomp Very Berry Toothpaste Tablets Refill – Nano Hydroxyapatite Whitening Tablets for Enamel Strength, Sensitive Teeth Relief, Fluoride-Free, Travel-Friendly, Eco-Friendly Plastic-Free Oral Care

CHOMP Berry Toothpaste Tablets offer a fun and flavorful brushing experience with their naturally sweet berry taste, perfect if you prefer fruity flavors or have sensitive teeth. These tablets contain nano hydroxyapatite, a mineral that helps rebuild your enamel, reduce sensitivity, and gently whiten your teeth without harsh chemicals. They are free from fluoride, SLS, and artificial additives, providing a safe and gentle daily brushing option. Plus, the eco-friendly refill pouch helps you reduce plastic waste, making it an excellent choice for those who care about the environment while maintaining great oral care.

What We Like
Natural berry flavor
Enamel strengthening
Fluoride-free formula
Eco-friendly refill pouch

Mouthology Nano Hydroxyapatite Toothpaste

NHAtp
4 Ounce (Pack of 1)
Mouthology Nano Hydroxyapatite Toothpaste Cover
Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening*, Xylitol Toothpaste for Adults, Supports Enamel Care*, Appropriate for Sensitive Teeth*, SLS Free, Mint 4oz (USA Made)

Mouthology Toothpaste offers advanced enamel care inspired by NASA research. With a full 10% Nano Hydroxyapatite, it effectively restores and strengthens your tooth enamel, providing superior protection against damage. This toothpaste is designed for natural whitening without harsh chemicals, ensuring you achieve a brighter smile without sensitivity. Plus, it's completely fluoride-free, making it a safe choice for everyone, including children. Made in the USA with clean, natural ingredients, it promotes overall oral health while being gentle on your mouth.

What We Like
Enamel restoration
Natural whitening
Fluoride-free
Safe for all ages
Made with natural ingredients

Davids Hydroxi Nano Hydroxyapatite Toothpaste

nano hydroxyapatite toothpaste
4 Ounce (Pack of 1)
Davids Hydroxi Nano Hydroxyapatite Toothpaste Cover
Davids Hydroxi Fluoride Free Nano Hydroxyapatite Toothpaste for Remineralizing Enamel & Sensitive Relief, Whitening, Antiplaque, SLS Free, Natural Peppermint, 4 oz, Made in USA

Davids Nano Hydroxyapatite Paste uses a unique ingredient called Nano Hydroxyapatite, which makes up most of your tooth enamel. This helps rebuild and strengthen your teeth while reducing sensitivity, unlike traditional fluoride toothpastes. It also gently whitens your teeth using mild polishing agents, so you get a brighter smile without the discomfort caused by harsh bleaches. The toothpaste avoids harsh chemicals like SLS and artificial additives, relying instead on natural, plant-based ingredients. This makes it a safer and gentler choice for everyday use, keeping your mouth fresh and healthy with a natural peppermint flavor.

What We Like
Enamel remineralization
Gentle whitening
Sensitivity relief
Natural ingredients
Fluoride and SLS free

GuruNanda Hydroxyapatite Toothpaste

13-27-4OZ-08494-48
Green
GuruNanda Hydroxyapatite Toothpaste Cover
GuruNanda Hydroxyapatite Toothpaste, SLS & Fluoride Free, Whitening Toothpaste with Tongue Scraper & Squeezer - Freshens Breath, Fights Plaque - Natural CocoMint Jasmine Neem, 4.2oz

GuruNanda Toothpaste is designed to enhance your oral health with its Hydroxyapatite formula. This ingredient not only cleans your teeth effectively but also helps remineralize enamel, contributing to a brighter smile. If you have sensitive teeth, this toothpaste is a great choice as it removes plaque while promoting healthy gums. You'll appreciate the blend of natural ingredients like neem, jasmine, and various oils that freshen your breath and invigorate your mouth. For optimal results, use it alongside oil-pulling products from GuruNanda. It's a dentist-recommended option that prioritizes your well-being.

What We Like
Enhances enamel health
Promotes gum health
Natural ingredients
Freshens breath
Recommended for sensitive teeth

Biöm NOBS Toothpaste Tablets

N085
1 Month
Biöm NOBS Toothpaste Tablets Cover
NOBS (No Bad Stuff) Toothpaste Tablets - Nano Hydroxyapatite, Fluoride & Plastic Free, Eco & Travel Friendly - Remineralize with NHA (1 Month)

Biöm NOBS Tablets offer a fluoride-free solution for your oral care needs, utilizing the benefits of nanohydroxyapatite to help remineralize your teeth. You can enjoy a refreshing minty taste while knowing your toothpaste is eco-friendly, packaged in a glass jar that eliminates plastic waste. Perfect for travelers, these tablets easily comply with TSA regulations, allowing you to take your dental care on the go without worrying about liquid restrictions. With Biöm, you contribute to environmental stewardship by choosing a product free from plastics and BPAs, ensuring a healthier planet while maintaining your smile.

What We Like
Fluoride-free formula
Eco-friendly glass packaging
Travel-friendly design
Supports environmental sustainability

Boka Fluoride Free Toothpaste

BOK-FGS-P002-01-AK1US
4 Ounce (Pack of 1)
Boka Fluoride Free Toothpaste Cover
Boka Fluoride Free Toothpaste Nano Hydroxyapatite Toothpaste - Strawberry Mango Flavor, 4 oz 1Pk US Manufactured

Boka Toothpaste is designed to enhance your oral health with its advanced formula featuring Nano Hydroxyapatite. This ingredient not only helps to remineralize your teeth but also supports gum health and repairs enamel. You can enjoy a delightful brushing experience with its unique Strawberry Mango flavor, making dental care feel less like a chore. Plus, it's completely free from harmful additives like fluoride and sulfates, ensuring a safe and non-toxic option for daily use. With Boka, you can take your oral hygiene to new heights while enjoying a refreshing taste.

What We Like
Supports gum health
Repairs tooth enamel
Remineralizes teeth
Delicious flavor
Free from harmful additives
#TOP 8

Generic Hydroxyapatite Toothpaste 2PCS

Generic
HT1211
Generic Hydroxyapatite Toothpaste 2PCS Cover
2PCS Hydroxyapatite Toothpaste, Nano-Hydroxyapatite Toothpaste for Strengthens Enamel, Gentle and Effective Formula, Fluoride-Free, Fresh Breath, Mint Flavor

The Generic Hydroxyapatite Toothpaste offers gentle yet effective care for your teeth. It uses natural hydroxyapatite to help rebuild and strengthen your enamel, protecting your teeth from daily wear. If you have sensitive teeth, this toothpaste is ideal because it has a pH-neutral, fluoride-free formula that reduces irritation and soothes discomfort while cleaning. You’ll also enjoy long-lasting fresh breath thanks to natural peppermint that fights odor-causing bacteria and helps keep plaque under control. This toothpaste is a safe choice if you prefer a mild, fluoride-free option for your daily dental routine.

What We Like
Enamel repair
Gentle on sensitive teeth
Long-lasting fresh breath
Fluoride-free formula
#TOP 9

Ollie 10% Nano Hydroxyapatite Toothpaste

OLP1
Pack of 1 (4 Ounce)
Ollie 10% Nano Hydroxyapatite Toothpaste Cover
Ollie Fluoride Free 10% Nano Hydroxyapatite Toothpaste for Remineralizing Enamel, Sensitive Teeth & Whitening, Clean Mint 4oz (Pack of 1)

The Ollie Hydroxyapatite Toothpaste offers a unique way to care for your teeth by using rod-shaped hydroxyapatite crystals that closely resemble your natural enamel. This helps repair tiny cracks, reduce tooth sensitivity, and strengthen your enamel for lasting protection against cavities. Its fluoride-free formula contains 10% nano-hydroxyapatite, giving you cavity defense without fluoride’s potential drawbacks. The toothpaste delivers a refreshing clean mint flavor with natural peppermint oil, providing fresh breath without harshness. Plus, it naturally whitens your teeth by smoothing and rebuilding the surface, avoiding abrasive ingredients that can damage enamel over time.

What We Like
Rod-shaped hydroxyapatite
Fluoride-free cavity defense
Refreshing mint flavor
Natural whitening effect
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is hydroxyapatite toothpaste good for your teeth?

Yes, incorporating hydroxyapatite toothpaste into your oral health regimen is an excellent way to prevent and reverse demineralization. It helps maintain white teeth, a balanced oral microbiome, and healthy gums.

2. Is hydroxyapatite in toothpaste safe?

Yes, hydroxyapatite is safe to use in toothpaste, and it can be an alternative to fluoride. In fact, some toothpaste formulas combine hydroxyapatite and fluoride as both minerals can repair tooth decay damage.

3. Is hydroxyapatite FDA approved?

Nano-hydroxyapatite is not FDA approved in the US, although it has been used for many years in countries like Japan, the Netherlands, and Canada.

4. How long to leave hydroxyapatite on teeth?

For the most beneficial impact, it is recommended to leave hydroxyapatite on the teeth for up to 10 minutes to allow the nano-hydroxyapatite crystals to effectively remineralize the teeth.

5. What are the issues with hydroxyapatite?

Hydroxyapatite particles can potentially block dentinal tubules, leading to tooth sensitivity and deeper tooth decay. However, the size of the hydroxyapatite particles is important in determining their effectiveness.

6. Can you reverse cavities with hydroxyapatite?

Yes, you can reverse and prevent cavities by remineralizing your teeth, and hydroxyapatite is a powerful and safe way to achieve that.

7. Does hydroxyapatite cause kidney stones?

Hydroxyapatite is a common component of most idiopathic calcium oxalate (CaOx) stones and Randall plaques. HAP crystallites on the surface of renal epithelial cells can induce the formation of Randall plaques and even kidney stones.

Editor's Notes

During our hydroxyapatite toothpaste research, we found 24 hydroxyapatite toothpaste products and shortlisted 9 quality products. We collected and analyzed 431,767 customer reviews through our big data system to write the hydroxyapatite toothpaste list. We found that most customers choose hydroxyapatite toothpaste with an average price of $15.35.

The hydroxyapatite toothpaste are available for purchase. We have researched hundreds of brands and picked the top brands of hydroxyapatite toothpaste, including Boka, CHOMP, Mouthology, Davids, GuruNanda. The seller of top 1 product has received honest feedback from 2,666 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.