Best Hypoallergenic Mattress Pads of 2025

The Amazon Basics Mattress Topper offers an added layer of comfort and protection to your bed. It comes in a Queen size and has a poly-cotton fabric for breathability. The lightweight hypoallergenic fill is ideal for allergy sufferers and is quilted to prevent plush fill from shifting. The knitted fabric sides have elastic for a secure fit on mattresses up to 18 inches deep. With its easy care and safe for high-temperature features, you can machine wash and dry it with no hassle. Not only does the Amazon Basics Mattress Topper add comfort and protection to your bed, but it also helps you sleep better and wake up feeling refreshed.

The Sunflower Queen Mattress Pad is a quilted mattress protector with an elasticized deep pocket fitting that measures 18" but can be stretched up to 22". Made of 100% cotton, this mattress cover wicks away moisture and is noiseless for a comfortable and quiet night's sleep. Certificated by OEKO-TEX and BSCI, the diamond-quilted design is elegant and fits all decorations. The mattress pad is sold directly to consumers from the manufacturer at a lower-than-average price and comes with a 10-year warranty.

The HALO DreamWeave Pad is designed for your baby's comfort and safety. Its fully breathable core and quilted cover promote maximum airflow, ensuring your newborn stays at a comfortable temperature while sleeping. This pad is tailored to fit the HALO BassiNest Sleeper, making it an ideal choice for parents using this popular product. For added convenience, the cover is machine washable, allowing you to keep it clean with ease, while the core can simply be rinsed off in the shower. Plus, it’s made from hypoallergenic materials, free from harmful substances like foam and latex, so you can have peace of mind knowing your baby is resting on a safe surface.

Experience the comfort of Abit Comfort Mattress Pad Queen, a luxurious cotton poly blend that feels like buttery soft. It fits almost all queen-size beds with a depth of up to 21 inches. Cleaning is a breeze, and it won't shrink or fray in the wash. Try it risk-free for 30 days, and if you don't love it, return it for a full refund.

The Foifope Waterproof Mattress Pad is crafted from 100% organic cotton, ensuring a soft and natural feel while protecting your mattress from spills like sweat and urine. Its innovative airflow technology allows for excellent air circulation, promoting a comfortable sleeping environment. This hypoallergenic mattress pad shields you from dust and moisture, creating a cleaner space for restful sleep. Additionally, it features an easy-fit design with an elastic band, allowing it to snugly fit mattresses up to 18 inches deep, making maintenance a breeze with machine wash and dry convenience.

The MALOUF Mattress Pad is designed for ultimate comfort and convenience. Its pure cotton cover features stylish box stitching and diamond quilting, adding an elegant touch to your bedding. You will appreciate its quiet and breathable nature, ensuring a peaceful night's sleep without any rustling noises. The soft, low loft fill promotes better airflow, helping you stay cool and comfortable throughout the night. Plus, maintenance is a breeze since it is machine washable and can be tumble dried on low. This mattress pad is a perfect addition to enhance your sleeping experience.

Royal Heritage Home Reusable Waterproof Underpads, also known as Royal Heritage Underpads, are the perfect solution for anyone in need of superior absorption and protection against leaks. With a highly absorbent core that can hold up to 10 cups of liquid, these underpads ensure that you stay dry and comfortable throughout the night. The durable, waterproof knitted vinyl backing not only prevents seepage and staining but also provides a non-slip grip on various surfaces, keeping the pad securely in place. Made from high-quality materials, these underpads are hypoallergenic and gentle on the skin, making them suitable for individuals with allergies or sensitivities. They are incredibly easy to clean - simply toss them in the washing machine and they'll come out looking and feeling like new. The versatility of these underpads allows for use in various settings, such as in the car, on the couch, or on a wheelchair. The breathable material promotes airflow, ensuring a comfortable experience even during extended periods of use.

The Stearns & Foster Mattress Pad offers a luxurious sleeping experience with its soft 400 thread count cotton top. You'll enjoy exceptional comfort thanks to its generous 12 oz. per square yard filling, which provides a plush layer for your mattress. The hypoallergenic PrimaLoft polyester filling ensures that you can sleep peacefully without worrying about allergens. Additionally, the SureGrip skirt keeps the pad securely in place, fitting mattresses ranging from 9 to 18 inches deep. This means you can rest easy knowing your mattress pad will stay snug all night long.

The HOMTEC Waterproof Mattress Pad offers excellent protection for your mattress against spills and stains, thanks to its waterproof TPU coated fabric. You will enjoy a soft touch with its 210 gsm down alternative microfiber filling that adds comfort without sacrificing durability. The top layer is made from OEKO-TEX certified cotton, ensuring it is hypoallergenic and breathable, which helps you sleep better. Designed with an elegant quilted pattern and deep pockets, it fits mattresses up to 22 inches deep, making it a versatile choice for your bedding needs.

The Tateufeu Mattress Cover is designed to enhance your sleep experience. Its hypoallergenic filling ensures that you enjoy a comfortable and allergy-free night. This cover also offers excellent protection for your mattress, shielding it from spills, stains, and daily wear. Additionally, its breathable fabric promotes airflow to keep you cool while you sleep. With a deep pocket design, it fits snugly on various mattress sizes, ensuring a secure fit every time. You can rest easy knowing that this cover is crafted with safety in mind, free from harmful chemicals.