Best Ergonomic Mac Gaming Mice of 2025

The Razer Basilisk V3 Gaming Mouse is a top-of-the-line device that offers gamers a wide range of features that can be customized to suit their needs. This mouse is ergonomically designed with a thumb rest and optimally positioned buttons for quick and easy access. With 11 programmable buttons, users can assign macros and secondary functions to execute essential actions. Its 11 Razer Chroma RGB lighting zones allow users to customize each zone from over 16.8 million colors and countless lighting effects. Additionally, its Optical Mouse Switches Gen 2 ensure crisp, responsive execution at a blistering 0.2ms actuation speed for up to 70 million clicks. The mouse also features a Focus+ 26K DPI Optical Sensor for pixel-precise accuracy.

The Redragon M602-RGB Wired Gaming Mouse is a must-have for serious gamers. Its high-precision sensor and gaming-grade micro switches deliver pinpoint accuracy, extreme responsiveness, and greater durability. With up to 7200 DPI, 10G acceleration, and 7 programmable buttons, this mouse gives you an edge over your competition. Its ergonomic design ensures comfort and reduced click fatigue, while the 7 different backlight modes provide total personalization. The built-in weight tuning, anti-skid scroll wheel, and durable smooth TEFLON feet pads offer ultimate gaming control. Compatible with Windows and Mac OS, this mouse is a great addition to any gaming computer or laptop.

The Zelotes Gaming Mouse boasts a high-end optical engine with up to 7200 DPI resolution and five dpi levels, each with different LED indicator colors when changing. It also features 7 color breathing lights, a human ergonomic design for comfortable use and reduced fatigue, and an all copper build with magnetic ring and anti-jamming nylon braided line.

The RaceGT Wired RGB Gaming Mouse is a wired ergonomic mouse that provides a fast response and easy plug-and-play. It comes with seven color gradient breathing light effect, providing a fancy gaming environment, and has an ergonomic shape that fits naturally in your hand to reduce click fatigue. With four adjustable DPI, it meets your gaming and daily work needs. It is widely compatible with Windows7/8/10/XP, Vista7/8, and Linux, making it perfect for desktop, laptop, PC, MacBook, and other devices.

Zeerkeer Gaming Mouse is a wireless vertical mouse designed to reduce muscle strain and eliminate damage caused by traditional computer mice. It features a scientific ergonomic design that helps alleviate wrist pain, shoulder fatigue, carpal tunnel syndrome, and tendonitis. With adjustable DPI settings of 1000/1600/2400, it provides smooth and precise tracking on various surfaces. The built-in rechargeable battery eliminates the need for buying batteries and the quick connect design allows for easy switching between wireless and charging cable connection. The addition of the forward and back buttons enhances work efficiency for web browsing. Compatible with Windows and Mac OS X, Zeerkeer Gaming Mouse is the perfect choice for gamers, internet surfers, and computer users.

The Uhuru Wireless Gaming Mouse is a reliable and precise gaming mouse that offers a range of features to enhance your gaming experience. With 2.4GHz transmission technology, the mouse provides a long-range connection, up to 50ft, with near-instantaneous response, allowing for zero delays and no jump during fierce gaming. The 5-level DPI adjustment, 7-color changeable backlight, and 6 programmable buttons make this mouse perfect for gaming and office use, providing extreme stability while gaming, such as League of Legends, World of Warcraft, DOTA, CS, etc. The transparent light effect is suitable for demand for more types of games, making your mouse multi-colored. The UHURU wireless gaming mouse is compatible with most systems including Windows 7 / 8 / 10 / XP, Vista 7 / 8, Mac OS and Linux, and the driver can be downloaded from their website.

The Lacolain Wireless Mouse enhances your gaming experience with its advanced features. Enjoy the freedom of movement with its 2.4GHz wireless connectivity, allowing you to operate up to 33 feet away from your device. You can easily switch between three DPI settings—800, 1200, and 1600—tailoring the sensitivity to your gameplay style. The Type-C fast charging means you can charge it while playing, and a full charge lasts over 21 days, ensuring you're always ready for action. Plus, with six customizable buttons, you can streamline your gaming commands for efficient multitasking.

The AULA SC580 Mouse offers versatile connectivity with three modes: 2.4G wireless, Bluetooth 5.0, and USB-C wired. This means you can easily switch between up to four devices, making it perfect for multitasking. With six adjustable DPI settings, you can tailor the sensitivity to match your gaming or work needs, ensuring precise cursor control. The mouse features six programmable buttons, allowing you to customize commands for a smarter gaming experience. Plus, its rechargeable battery lasts up to 14 days on a single charge, reducing downtime and enhancing your overall productivity.

The J-Tech Digital Ergonomic Vertical USB Mouse is designed to be used in a neutral "handshake" wrist and arm position, which helps reduce wrist pain. It has a removable palm rest and blue LED light, and adjustable DPI levels (800/1200/1600) to ensure precise tracking on a wide range of surfaces. The back/forward buttons near the thumb area add extra convenience, and it is compatible with various operating systems.

The SXBan Ergo Mouse is a wireless left-handed mouse designed with ergonomics in mind. Its ergonomic design fits the contour of your palm, providing maximum comfort during extended use. With the forward/backward thumb buttons, it is the perfect choice for internet surfers and gamers. The adjustable sensitivity, with options of 800/1200/1600 DPI, allows for smooth and precise tracking on a wide range of surfaces. The six buttons provide improved control over your computer's systems, making it ideal for tasks such as dragging and dropping, selecting large volumes of data, and casual gaming. The SXBan Ergo Mouse is a low-cost and effective solution for all your computing needs.