Best Thumb Button Mac Gaming Mice of 2025

The Razer Basilisk V3 Gaming Mouse is a top-of-the-line device that offers gamers a wide range of features that can be customized to suit their needs. This mouse is ergonomically designed with a thumb rest and optimally positioned buttons for quick and easy access. With 11 programmable buttons, users can assign macros and secondary functions to execute essential actions. Its 11 Razer Chroma RGB lighting zones allow users to customize each zone from over 16.8 million colors and countless lighting effects. Additionally, its Optical Mouse Switches Gen 2 ensure crisp, responsive execution at a blistering 0.2ms actuation speed for up to 70 million clicks. The mouse also features a Focus+ 26K DPI Optical Sensor for pixel-precise accuracy.

The Corsair Scimitar Elite Mouse is designed for gamers who need precision and comfort. With 16 customizable buttons, you can easily assign actions and macros, enhancing your gameplay experience. Its adjustable button slider allows you to position the buttons perfectly for your thumb, reducing strain during long gaming sessions. The quick and versatile wireless connection ensures a lag-free experience, whether you're playing on PC or Mac. Plus, enjoy up to 150 hours of playtime on a single charge, allowing you to game without interruptions.

The J-Tech Digital Ergonomic Vertical USB Mouse is designed to be used in a neutral "handshake" wrist and arm position, which helps reduce wrist pain. It has a removable palm rest and blue LED light, and adjustable DPI levels (800/1200/1600) to ensure precise tracking on a wide range of surfaces. The back/forward buttons near the thumb area add extra convenience, and it is compatible with various operating systems.

The AULA S12Pro Mouse is designed for gamers seeking precision and comfort. With a high-end optical engine, it offers a maximum DPI of 12800, enabling you to enjoy accurate positioning during intense gameplay. You can easily switch between six adjustable DPI levels, catering to both gaming and everyday tasks. The RGB lighting features 13 effects, allowing you to personalize your gaming setup. Additionally, its ergonomic design ensures comfort during long gaming sessions, reducing fatigue and enhancing your overall experience.