Best Thumb Button Mac Gaming Mice of 2026

James Ryan Avatar
James Ryan
Last Updated: Jan 9, 2026

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Thumb button Mac gaming mice are a game-changer for avid gamers who use Mac computers. These mice are designed with a unique thumb button feature that allows gamers to execute multiple commands with just one click. They are ergonomically designed to fit comfortably in the hand, reducing the risk of hand fatigue during extended gaming sessions. These mice are compatible with Mac computers, making them an excellent choice for Mac gamers who are looking for a high-performance gaming mouse. The thumb button Mac gaming mice are available in different models and designs, so gamers can choose the one that best suits their needs and preferences.

At a Glance: Our Top Picks

Razer Basilisk V3 Gaming Mouse: Customizable and Ergonomic Cover #TOP 1
Razer Basilisk V3 Gaming Mouse: Customizable and Ergonomic
ftb score rating icon 9.8
Logitech G PRO X Superlight 2 Wireless Mouse Cover #TOP 2
Logitech G PRO X Superlight 2 Wireless Mouse
ftb score rating icon 9.7
Corsair Scimitar Elite RGB Wireless Mouse Cover #TOP 3
Corsair Scimitar Elite RGB Wireless Mouse
ftb score rating icon 9.5

Top 3 Thumb Button Mac Gaming Mice

Razer Basilisk V3 Gaming Mouse: Customizable and Ergonomic

RZ01-04000100-R3U1
Black
Mouse
Razer Basilisk V3 Gaming Mouse: Customizable and Ergonomic Cover
Razer Basilisk V3 Customizable Ergonomic Gaming Mouse: Fastest Gaming Mouse Switch - Chroma RGB Lighting - 26K DPI Optical Sensor - 11 Programmable Buttons - HyperScroll Tilt Wheel - Classic Black

The Razer Basilisk V3 Gaming Mouse is a top-of-the-line device that offers gamers a wide range of features that can be customized to suit their needs. This mouse is ergonomically designed with a thumb rest and optimally positioned buttons for quick and easy access. With 11 programmable buttons, users can assign macros and secondary functions to execute essential actions. Its 11 Razer Chroma RGB lighting zones allow users to customize each zone from over 16.8 million colors and countless lighting effects. Additionally, its Optical Mouse Switches Gen 2 ensure crisp, responsive execution at a blistering 0.2ms actuation speed for up to 70 million clicks. The mouse also features a Focus+ 26K DPI Optical Sensor for pixel-precise accuracy.

What We Like
Ergonomic design with thumb rest and optimally positioned buttons
11 programmable buttons for executing essential actions
11 Razer Chroma RGB lighting zones for customization
Optical Mouse Switches Gen 2 with zero unintended misclicks
Focus+ 26K DPI Optical Sensor for pixel-precise accuracy

Logitech G PRO X Superlight 2 Wireless Mouse

910-007328
Black
One Size
Logitech G PRO X Superlight 2 Wireless Mouse Cover
Logitech G PRO X Superlight 2 DEX Wireless Gaming Mouse, 60g pro-Grade Right-Handed Mouse with 5 programmable Buttons, USB-C Charging, 44k DPI Sensor, up to 8 kHz Polling for PC/Mac - Black

The Logitech G PRO X Superlight 2 wireless mouse is crafted with input from top esports players to help you reach your best performance. Its right-handed ergonomic design and programmable side buttons provide comfort and adaptability, making it easier to play your way. Equipped with the advanced HERO 2 sensor, it offers precise tracking and high sensitivity, which means you can expect smooth and accurate movements in your games. The LIGHTSPEED wireless technology ensures a fast, reliable connection with minimal lag, so your actions register instantly. Overall, this mouse is built to give you a competitive edge with comfort, precision, and quick responsiveness.

What We Like
Ergonomic right-handed design
Advanced HERO 2 sensor
LIGHTSPEED wireless tech
Programmable side buttons
#TOP 3

Corsair Scimitar Elite RGB Wireless Mouse

CH-9314311-NA
Black
Corsair Scimitar Elite RGB Wireless Mouse Cover
Corsair Scimitar Elite RGB Wireless MMO Gaming Mouse - 26,000 DPI - 16 Programmable Buttons - Up to 150hrs Battery - iCUE Compatible - Black

The Corsair Scimitar Elite Mouse is designed for gamers who need precision and comfort. With 16 customizable buttons, you can easily assign actions and macros, enhancing your gameplay experience. Its adjustable button slider allows you to position the buttons perfectly for your thumb, reducing strain during long gaming sessions. The quick and versatile wireless connection ensures a lag-free experience, whether you're playing on PC or Mac. Plus, enjoy up to 150 hours of playtime on a single charge, allowing you to game without interruptions.

What We Like
16 customizable buttons
Adjustable for hand size
Quick wireless connection
150-hour battery life
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Can you use a gaming mouse on Mac?

Mac or PC, the Basics Don't Change Your basic needs from a gaming mouse don't change whether you're playing on Windows or macOS. It should feel light and well-balanced in your hand, with easily accessible buttons and a comfortable chassis that encourages an ergonomic grip.

2. Can you use mouse side buttons on Mac?

In the System Preferences window, click the Mouse or Keyboard & Mouse icon to open the preference pane. Click the Mouse tab, if needed. Assign the Primary Click mouse button to either the left or right mouse button. After you make your selection, the secondary click function is assigned to the remaining mouse button.

3. How do I use the extra buttons on my gaming mouse Mac?

A solution that comes builtin with Mac OSX (without third-party apps nor workarounds) is setting the mouse three buttons within Settings, Mission Control, Keyboard and Mouse Shortcuts. Here you'll be able to select the action for each of the buttons.

4. Do any mice work with Mac?

As with keyboards, any USB or Bluetooth mouse (including wireless mice that connect through a USB dongle) will work with the Mac; you'll be able to click and right-click just as you did under Windows, and if your mouse has a scrollwheel, that will work, too.

Editor's Notes

During our thumb button mac gaming mice research, we found 16 thumb button mac gaming mice products and shortlisted 3 quality products. We collected and analyzed 161,346 customer reviews through our big data system to write the thumb button mac gaming mice list. We found that most customers choose thumb button mac gaming mice with an average price of $75.11.

The thumb button mac gaming mice are available for purchase. We have researched hundreds of brands and picked the top brands of thumb button mac gaming mice, including Razer, Logitech G, Corsair. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
James Ryan Avatar

James Ryan is a young writer with a degree in journalism. He’s well-versed in topics such as literature, video games, and gaming devices. In his free time, he enjoys editing, playing games, exercising and photography.