Best Arthritis Pain Relief Medications for Muscle Pain of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 4, 2025

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There are a variety of arthritis pain relief medications available to help alleviate muscle pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen can reduce inflammation and pain, while acetaminophen can help with pain but not inflammation. Topical creams and gels containing menthol, capsaicin, or salicylates can also provide temporary relief. Muscle relaxants such as cyclobenzaprine or tizanidine can help ease muscle spasms. It's important to consult with a healthcare provider before starting any new medication and to follow the dosage instructions carefully.

At a Glance: Our Top Picks

Hempvana Arthritis Relief Gel Cover #TOP 1
Hempvana Arthritis Relief Gel
ftb score rating icon 9.9
Boiron Arnicare Arthritis Cream - 2.5 oz Cover #TOP 2
Boiron Arnicare Arthritis Cream - 2.5 oz
ftb score rating icon 9.8
Australian Dream Arthritis Pain Relief Cream Cover #TOP 3
Australian Dream Arthritis Pain Relief Cream
ftb score rating icon 9.6

Top 8 Arthritis Pain Relief Medications for Muscle Pain

Hempvana Arthritis Relief Gel

14596
Arthritis
1 Ounce (Pack of 1)
Hempvana Arthritis Relief Gel Cover
Hempvana Arthritis Pain Relief Gel, Ultra-Strength for Arthritis in Muscles & Joints. Enriched with Hemp Seed Oil, AS-SEEN-ON-TV. Non-Greasy. Targeted Long-Lasting Arthritis Relief. Works Fast, 4 Oz.

Hempvana Arthritis Gel is a maximum strength formula designed to target and relieve pain fast. Made with 100% pure, cold-pressed hempseed oil, this gel provides cooling pain relief for joint and muscle pain associated with arthritis. The FDA-listed pain-fighting menthol offers active pain relief, while the inclusion of soothing Aloe enhances the overall soothing effect. With the added benefits of Arnica, Turmeric, and Camphor, this gel is great for relieving pain in various areas such as hands, knees, neck, elbows, shoulders, wrists, and feet. Experience fast and effective pain relief with Hempvana Arthritis Gel.

What We Like
Maximum strength formula
Cooling pain relief
Includes Arnica, Turmeric, and Camphor

Boiron Arnicare Arthritis Cream - 2.5 oz

2261311
White
Boiron Arnicare Arthritis Cream - 2.5 oz Cover
Boiron Arnicare Arthritis Cream with Devil’s Claw for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles – Quickly Absorbed & Fragrance-Free – 2.5 oz

Boiron Arnicare Arthritis Cream provides effective relief from minor arthritis pain, stiffness, and soreness. It is suitable for use on all joints and absorbs quickly into the skin, making it ideal for flare-ups. Unlike other creams, it contains no camphor, menthol, or other ingredients that cause burning or stinging, and has a light, non-greasy texture. As it is fragrance-free and does not contain parabens or dyes, it has no strong medicinal smell.

What We Like
Effective relief from minor arthritis pain, stiffness, and soreness
Non-greasy texture and quick absorption make it ideal for flare-ups
Free of camphor, menthol, and other ingredients that cause burning or stinging
#TOP 3

Australian Dream Arthritis Pain Relief Cream

6.94603E+11
2 Ounce (Pack of 1)
Australian Dream Arthritis Pain Relief Cream Cover
Australian Dream Arthritis Pain Relief Cream - Soothing, Non-Greasy Pain Relief Cream - Powerful Topical Arthritis Pain Relief Good for Muscle Aches or Joint Pain - 2 oz Jar

The Australian Dream Pain Relief cream is designed to provide soothing relief for muscle and joint discomfort. Its non-greasy and odorless formula absorbs quickly, making it convenient for you to use without any mess. This powerful cream requires only a small amount to effectively alleviate arthritis pain, ensuring you get the most out of your purchase. Formulated with histamine dihydrochloride, it offers temporary relief from minor aches and is perfect for easing strains, sprains, and bruises. With this cream, you can enjoy an active lifestyle without the distraction of pain.

What We Like
Fast-absorbing formula
Non-greasy and odorless
Effective for muscle and joint pain
Small amount needed
#TOP 4

Chattem Arthritis Pain Relief Cream

Chattem
PPAX1210285
Chattem Arthritis Pain Relief Cream Cover
Arthritis Hot Pain Relief Creme 3 oz (Pack of 2)

Chattem Pain Relief Cream is designed to provide quick relief from arthritis pain and discomfort. This heating rub works fast to soothe stiff joints and sore muscles, making daily activities easier for you. The long-lasting effects mean you can enjoy relief throughout your day without frequent reapplication. Whether you’re dealing with chronic pain or just occasional stiffness, this cream offers a convenient solution to help you feel more comfortable and active.

What We Like
Quick relief from pain
Effective for sore muscles
Long-lasting effects
Convenient application
#TOP 5

DCH Labs Warming Arthritis Roll-on

3 Ounce (Pack of 1)
DCH Labs Warming Arthritis Roll-on Cover
DCH Labs Warming Arthritis Pain Relief Roll-on, Deep Penetrating Capsaicin Blocks Your Muscle & Joint Pain Messengers, for Hands, Wrist, Feet, Knees & Back, 3 Ounces

DCH Labs Arthritis Roll-on is designed to provide effective relief from muscle and joint pain. Infused with 0.1% Capsaicin, this odorless and non-greasy formula harnesses the natural pain-relieving properties of chili peppers. It delivers a warming sensation that helps ease aches and pains related to arthritis, backaches, and sprains. This roll-on penetrates deeply to block pain signals, ensuring you feel relief where you need it most. Plus, its convenient roll-on application keeps your hands clean while targeting areas like toes, feet, and hands, making it easy to use throughout your day.

What We Like
Effective pain relief
Odor-free and non-greasy
Convenient roll-on application
Deep penetration for lasting relief
#TOP 6

Smith Amish Arthritis Cream 4.5 oz

Smith Amish
AA815
Smith Amish Arthritis Cream 4.5 oz Cover
Smith Amish Arthritis Cream. Soothing and Cooling. 4.5 oz jar

Smith Amish Arthritis Cream offers a soothing and cooling relief for your discomfort. Made with natural botanicals, it combines the benefits of tea tree, peppermint, eucalyptus, rosemary, and arnica, providing a gentle yet effective solution for muscle aches and joint pain. You can easily apply it to your knees, back, legs, and feet, making it convenient to target specific areas where you feel discomfort. With no harmful ingredients like petroleum derivatives or parabens, you can trust this cream to be a safe choice for your pain relief needs.

What We Like
Natural ingredients
Soothing relief
Easy application
No harmful additives
#TOP 7

Australian Dream Arthritis Pain Relief Cream

Australian Dream
2 Ounce (Pack of 1)
Australian Dream Arthritis Pain Relief Cream Cover
Australian Dream Arthritis Pain Relief Cream - Soothing, Non-Greasy Pain Relief Cream - Powerful Topical Arthritis Pain Relief Good for Muscle Aches or Joint Pain - 2 oz Tube

Australian Dream Pain Relief Cream is a powerful and effective solution for muscle and joint pains associated with arthritis, strains, sprains, and bruises. This non-greasy and odorless cream is easily absorbed, providing soothing relief to sore muscles and painful joints. With its high-quality formula containing histamine dihydrochloride, it temporarily relieves minor aches and pains, allowing you to move comfortably. The cream is also economical, as a little goes a long way in alleviating your arthritis pain. Trust Australian Dream, America's first premium topical analgesic pain reliever, to help you find relief and promote comfort.

What We Like
Soothing relief for muscle and joint pains
Easily absorbed and non-greasy
Economical, a little goes a long way
#TOP 8

GeriCare Arthritis Pain Relief Gel

4E-42FF-708H
GeriCare Arthritis Pain Relief Gel Cover
Topical Arthritis Pain Relief Gel Diclofenac Sodium 1% (NSAID) by GeriCare- Hand Wrist Elbow Foot Ankle Knee Extra-Strength Arthritis Pain Reliever- Anti-inflammatory Arthritis Pain Treatment- 3.53oz

The GeriCare Pain Relief Gel is an effective solution for arthritis pain. It contains Diclofenac Sodium 1% and provides advanced pain relief for people of any age. Unlike other creams that only mask the pain, this gel penetrates deep into the site of pain, treating it directly. It may take up to a week to unleash its long-lasting effect, but once it does, it keeps arthritis pain at bay for prolonged relief. In addition to relieving pain, it also has anti-inflammatory properties and helps reduce joint stiffness. The gel can be applied to any achy part of the body, providing targeted pain relief. With GeriCare's seal of excellence and 30 years of experience, you can trust this gel for your arthritis pain relief needs.

What We Like
Advanced pain relief
Targets pain at site
Anti-inflammatory properties
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is the best medicine for muscle and joint pain?

If you get sore muscles once in a while, you can take acetaminophen or a nonsteroidal anti-inflammatory drug (NSAID) like aspirin, ibuprofen, or naproxen to help ease the discomfort.

2. What is the most effective medicine for muscle pain?

Muscle ache or pulled/strained muscle. Ibuprofen typically works better for this kind of pain relief, due to the anti-inflammatory effects.

Editor's Notes

During our arthritis pain relief medication for muscle pain research, we found 24 arthritis pain relief medication for muscle pain products and shortlisted 8 quality products. We collected and analyzed 96,215 customer reviews through our big data system to write the arthritis pain relief medications for muscle pain list. We found that most customers choose arthritis pain relief medications for muscle pain with an average price of $16.83.

The arthritis pain relief medications for muscle pain are available for purchase. We have researched hundreds of brands and picked the top brands of arthritis pain relief medications for muscle pain, including Hempvana, Boiron, Australian Dream, Chattem, DCH Labs. The seller of top 1 product has received honest feedback from 338 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.