Best Arthritis Pain Relief Medications for Muscle Pain of 2026

Boiron Arnicare Arthritis Cream provides effective relief from minor arthritis pain, stiffness, and soreness. It is suitable for use on all joints and absorbs quickly into the skin, making it ideal for flare-ups. Unlike other creams, it contains no camphor, menthol, or other ingredients that cause burning or stinging, and has a light, non-greasy texture. As it is fragrance-free and does not contain parabens or dyes, it has no strong medicinal smell.

Hempvana Arthritis Gel is a maximum strength formula designed to target and relieve pain fast. Made with 100% pure, cold-pressed hempseed oil, this gel provides cooling pain relief for joint and muscle pain associated with arthritis. The FDA-listed pain-fighting menthol offers active pain relief, while the inclusion of soothing Aloe enhances the overall soothing effect. With the added benefits of Arnica, Turmeric, and Camphor, this gel is great for relieving pain in various areas such as hands, knees, neck, elbows, shoulders, wrists, and feet. Experience fast and effective pain relief with Hempvana Arthritis Gel.

The Icy Hot Original Small Pain Relief Patches (5 Count) provide powerful targeted relief for arms, neck, legs, and small areas. These patches temporarily relieve minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains, and bruises. They provide fast relief and can be worn up to 8 hours, and are easy to apply and comfortably stay in place for hours. It is the America's #1 topical pain relief brand among OTC topical analgesics.

The GeriCare Pain Relief Gel is an effective solution for arthritis pain. It contains Diclofenac Sodium 1% and provides advanced pain relief for people of any age. Unlike other creams that only mask the pain, this gel penetrates deep into the site of pain, treating it directly. It may take up to a week to unleash its long-lasting effect, but once it does, it keeps arthritis pain at bay for prolonged relief. In addition to relieving pain, it also has anti-inflammatory properties and helps reduce joint stiffness. The gel can be applied to any achy part of the body, providing targeted pain relief. With GeriCare's seal of excellence and 30 years of experience, you can trust this gel for your arthritis pain relief needs.

If you’re looking for fast and effective pain relief, Advil Liqui-Gels are a great choice. This product is recommended by doctors to help ease common aches like headaches, back pain, muscle soreness, arthritis discomfort, and even symptoms from the common cold. The fast-acting formula means you don’t have to wait long to feel better, letting you get back to your day quickly. As one of the leading over-the-counter pain relievers, Advil Liqui-Gels offer trusted relief when you need it most, making it a convenient option to keep on hand for various types of pain.

GeriCare Topical Arthritis Pain Relief Gel is an extra-strength pain reliever that helps reduce joint stiffness and inflammation. This topical NSAID Diclofenac targets pain at the site of application and provides long-lasting relief from arthritis pain in any part of the body. The gel penetrates deep into the skin to treat the pain rather than masking it, and it may take up to a week to fully unleash its effects. GeriCare has 30 years of experience in creating high-quality supplements and medical supplies.

Two Old Goats Arthritis Relief is a US-made lotion designed to provide fast relief for joint pain. When you apply it, you can expect it to start working within minutes, helping to ease discomfort quickly. It's not just for arthritis—you can also use it on sore muscles after exercise, making it a versatile option for pain relief. Plus, this lotion helps reduce inflammation caused by gout or injuries, so you feel better faster. On top of pain relief, it nourishes your skin with essential oils, keeping it moisturized and healthy while you treat your aches.

Chattem Pain Relief Cream is designed to provide quick relief from arthritis pain and discomfort. This heating rub works fast to soothe stiff joints and sore muscles, making daily activities easier for you. The long-lasting effects mean you can enjoy relief throughout your day without frequent reapplication. Whether you’re dealing with chronic pain or just occasional stiffness, this cream offers a convenient solution to help you feel more comfortable and active.

The Capzix Pain Relief Cream is designed to help you manage tough pain with its high-strength formula. It offers a warming sensation that soothes sore joints and muscles, making it ideal if you suffer from arthritis, back pain, strains, or sprains. The cream contains 0.1% Capsaicin, a natural ingredient from chili peppers, which works by gently blocking pain signals to your brain. This means you can feel relief right where you need it. Plus, the cream is odor-free and non-greasy, so you can apply it without worrying about any strong smells or sticky residue.