Best Arthritis Pain Relief Medication Gels of 2025

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Arthritis pain can be debilitating and often requires medication to manage the symptoms. One option for relief is using arthritis pain relief medication gels. These gels are designed to be applied topically to the affected area and work by reducing inflammation and pain. They can be especially helpful for those who have trouble taking oral medication or who experience side effects from traditional pain relievers. Some examples of arthritis pain relief medication gels include Voltaren Gel, Biofreeze, and Bengay Ultra Strength Cream. It is important to speak with a healthcare provider before using any new medication or treatment for arthritis pain.
At a Glance: Our Top Picks
Top 10 Arthritis Pain Relief Medication Gels
Voltaren Arthritis Pain Gel - 3.5 oz/100 g Tubes (Pack of 2)
Voltaren Arthritis Pain Gel is a doctor-recommended, clinically proven solution that offers powerful topical pain relief for arthritis sufferers. This nonsteroidal anti-inflammatory gel penetrates deep to treat arthritis pain at the source of inflammation, improving mobility and reducing stiffness, aches, and pains. With two 3.5 oz/100 g tubes, Voltaren provides an alternative to pills, combining the benefits of an arthritis cream and gel for arthritis pain management.
HealthCareAisle Diclofenac Gel for Arthritis Pain Relief
The HealthCareAisle Diclofenac Gel is a clinically proven arthritis pain relief medicine that targets painful inflammation in the hand, wrist, elbow, foot, ankle, and knee. It contains the same active ingredient as Voltaren Arthritis Pain Gel and is a Non-Steroidal Anti-Inflammatory Drug (NSAID). You can apply it up to 4 times a day for up to 21 days, or as directed by your doctor. Follow the package label for directions, warnings, and other important information.
Voltaren Arthritis Pain Gel
Voltaren Arthritis Pain Gel is a non-prescription, clinically proven topical pain relief gel that is the number 1 doctor recommended brand for arthritis pain relief. The 5.29 oz/150 g tube offers prescription strength arthritis pain relief by reducing stiffness, aches and pains and improving mobility. It uses diclofenac sodium topical gel to penetrate deep and attack arthritis pain directly at the source of inflammation, making it an alternative to pills and a combination of arthritis cream and gel for arthritis pain management.
Voltaren Arthritis Pain Gel
Voltaren Arthritis Pain Gel is a doctor recommended topical pain relief brand that provides prescription strength arthritis pain relief. It is clinically proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains. This nonsteroidal anti-inflammatory gel penetrates deep to attack arthritis pain directly and treats arthritis pain rather than just masking it. It comes in a tube with an easy twist cap and includes a dosing card for proper dosage. The gel is paraben and dye-free, non-greasy and clean scented, and can be applied on up to two joints at the same time for hand pain, wrist pain, elbow pain, ankle pain, foot pain, or knee pain relief.
Voltaren Arthritis Pain Gel - Amazon Exclusive
Voltaren Arthritis Pain Gel is a doctor recommended nonsteroidal anti-inflammatory gel that provides powerful topical arthritis pain relief. This Amazon exclusive product includes one 3.5 oz/100 g tube and one 0.71 oz/20 g travel size tube. The clinically proven formula relieves arthritis pain, improves mobility, and reduces stiffness, aches, and pains to provide prescription strength arthritis pain relief. The gel penetrates deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain rather than just masking it.
Hempvana Arthritis Relief Gel
Hempvana Arthritis Gel is a maximum strength formula designed to target and relieve pain fast. Made with 100% pure, cold-pressed hempseed oil, this gel provides cooling pain relief for joint and muscle pain associated with arthritis. The FDA-listed pain-fighting menthol offers active pain relief, while the inclusion of soothing Aloe enhances the overall soothing effect. With the added benefits of Arnica, Turmeric, and Camphor, this gel is great for relieving pain in various areas such as hands, knees, neck, elbows, shoulders, wrists, and feet. Experience fast and effective pain relief with Hempvana Arthritis Gel.
Curist Diclofenac Arthritis Cream Gel 1%
The Curist Arthritis Pain Relief is designed to help you manage joint pain effectively. This maximum strength gel penetrates deeply to target inflammation, providing relief from discomfort and restoring mobility with regular use. Unlike other treatments that merely mask the pain, this gel works over time to reduce arthritis pain in areas like your hands, wrists, and knees. You can apply it up to four times a day, and while it may take a few days to see full effects, it offers a non-greasy finish for your convenience.
Amazon Basic Care Arthritis Pain Relieving Gel
Motrin Arthritis Pain Relief Gel, 3.53 Oz
Motrin Arthritis Pain Relief Diclofenac Sodium Topical Gel 1% is a fragrance-free anti-inflammatory cream that relieves arthritis pain and reduces inflammation, stiffness, and improves mobility in hands, wrists, elbows, knees, feet, and ankles. One tube of 3.53 oz contains 1% diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID). It may take up to 7 days for pain relief, and can be used up to 4 times a day, with 2 grams for each upper body area, and 4 grams for each lower body area.
HealthCareAisle Diclofenac Gel
HealthCareAisle Arthritis Pain Relief Gel is a clinically proven medication that provides temporary relief for arthritis pain. With its active ingredient, Diclofenac Sodium Topical Gel 1%, it targets painful inflammation in various areas of the body such as the hand, wrist, elbow, foot, ankle, and knee. Comparable to the national brand, this gel can be applied up to 4 times a day for 21 days or as directed by your doctor. Its easy application and fast-acting formula make it a convenient choice for arthritis pain relief. The package label provides important information, warnings, and directions, ensuring safe and effective use. Trust HealthCareAisle Arthritis Pain Relief Gel to help you manage your arthritis pain effectively.
Frequently Asked Questions (FAQs)
1. What gel can I use for arthritis?
Voltarol gels are medications that can help to relieve joint pain with various causes. Voltarol Osteoarthritis Joint Pain Relief Gel can relieve some of the pain linked to mild osteoarthritis of the knees or fingers.
2. Can I buy Voltaren Gel over-the-counter?
Voltaren Arthritis Pain Gel is a topical nonsteroidal anti-inflammatory (NSAID) gel with a proven safety profile for your arthritis pain. Now, you can buy Voltaren over the counter. Formerly a prescription product, it has been trusted by patients and doctors in the U.S. for 10+ years.
3. Is Voltaren Gel just for arthritis?
Like other NSAIDs, Voltaren (diclofenac) works by reducing inflammation in the body. When taken in oral form, it's used to treat pain related to such forms of arthritis as osteoarthrtis, rheumatoid arthritis, and ankylosing spondylitis. The oral version of this drug is still available only by prescription.
4. Does Voltaren Gel work immediately?
Voltaren gel contains an NSAID medication that is similar to the pain drug ibuprofen. It works by reducing substances in the body that cause pain and inflammation and works best on small joints. Voltaren topical gel is not for immediate relief and may take up to 7 days to work.
During our arthritis pain relief medication gel research, we found 24 arthritis pain relief medication gel products and shortlisted 10 quality products. We collected and analyzed 458,158 customer reviews through our big data system to write the arthritis pain relief medication gels list. We found that most customers choose arthritis pain relief medication gels with an average price of $17.01.
The arthritis pain relief medication gels are available for purchase. We have researched hundreds of brands and picked the top brands of arthritis pain relief medication gels, including Voltaren, HealthCareAisle, Hempvana, Curist, Motrin. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.