Best Capsule Antacids of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 16, 2026

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Capsule antacids are a popular solution for individuals who experience heartburn, acid reflux, or other digestive issues. These small, easy-to-swallow capsules work quickly to neutralize stomach acid and provide relief from discomfort. Capsule antacids come in a variety of strengths and formulas to suit different needs and preferences. Some contain magnesium or calcium, while others are designed to be taken only as needed or on a regular basis. Capsule antacids are a convenient option for those who need quick and effective relief from digestive discomfort.

At a Glance: Our Top Picks

Nexium 24HR Acid Reducer Capsules 42 Count Cover #TOP 1
Nexium 24HR Acid Reducer Capsules 42 Count
ftb score rating icon 9.8
Amazon Esomeprazole Magnesium Capsules, 20mg, 42 Count Cover #TOP 2
Amazon Esomeprazole Magnesium Capsules, 20mg, 42 Count
ftb score rating icon 9.7
HealthCareAisle Omeprazole 20mg Capsules Cover #TOP 3
HealthCareAisle Omeprazole 20mg Capsules
ftb score rating icon 9.5

Top 10 Capsule Antacids

#TOP 1

Nexium 24HR Acid Reducer Capsules 42 Count

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Nexium 24HR Acid Reducer Capsules 42 Count Cover
Nexium 24HR Acid Reducer Heartburn Relief Capsules for All-Day and All-Night Protection from Frequent Heartburn, Heartburn Medicine with Esomeprazole Magnesium - 42 Count

Nexium 24HR Acid Reducer offers you full-day and night relief from frequent heartburn with just one easy-to-swallow capsule daily. It works by blocking your stomach’s acid production right at the source, helping to prevent heartburn before it starts. The delayed-release formula targets active acid pumps in your stomach, giving you long-lasting protection so you can enjoy your day and sleep peacefully without discomfort. With 42 capsules in each pack, Nexium 24HR Acid Reducer is a convenient option to keep on hand for consistent heartburn control.

What We Like
Effective heartburn relief
Fast-acting results
Easy to swallow capsules
Consistent daily protection
Good value pack

Amazon Esomeprazole Magnesium Capsules, 20mg, 42 Count

Amazon Basic Care
S0062AN
Amazon Esomeprazole Magnesium Capsules, 20mg, 42 Count Cover
Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg, Acid Reducer, Heartburn Medicine, 42 Count

Amazon Esomeprazole Magnesium Capsules are an effective heartburn treatment that inhibits acid production, allowing you to enjoy foods and beverages that could cause frequent heartburn. These capsules are clinically proven to treat frequent heartburn that occurs 2 or more days a week. Take one capsule every 24 hours for 14 days for best results. With the active ingredient esomeprazole, these capsules are comparable to Nexium 24 HR. Plus, they are gluten-free, making them a great choice for those with dietary restrictions.

What We Like
Effective heartburn treatment
Clinically proven to treat frequent heartburn
Comparable to Nexium 24 HR
Gluten-free

HealthCareAisle Omeprazole 20mg Capsules

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Capsule
HealthCareAisle Omeprazole 20mg Capsules Cover
HealthCareAisle Omeprazole 20 mg, 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn, 42 Count (Pack of 1)

HealthCareAisle Omeprazole 20mg Capsules are an effective medicine for treating frequent heartburn. The capsules contain an acid reducer that stops heartburn by inhibiting the proton pumps in the stomach from producing excess acid. You can expect relief for up to 24 hours with just one capsule per day, and it is comparable to the national brand, Prilosec OTC. However, it is important to note that the capsules are not for immediate relief and may take 1 to 4 days for the full effect to take place.

What We Like
Provides all-day relief for up to 24 hours
Contains the same active ingredient as Prilosec OTC
Effective in treating frequent heartburn
#TOP 4

Nexium 24HR ClearMinis Acid Reducer Capsules 42 Count

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Nexium 24HR ClearMinis Acid Reducer Capsules 42 Count Cover
Nexium 24HR ClearMinis Acid Reducer Heartburn Relief Delayed Release Capsules for All-Day and All-Night Protection from Frequent Heartburn, Heartburn Medicine with Esomeprazole Magnesium - 42 Count

The Nexium 24HR ClearMinis offers effective relief from frequent heartburn with just one small, easy-to-swallow capsule daily. It works by blocking acid production directly at the source, helping you avoid the discomfort of heartburn throughout the day and night. These delayed-release capsules target your stomach’s acid pumps, stopping acid before it starts, so you can enjoy lasting comfort and restful sleep. With its compact size, the ClearMinis provide all the power of Nexium 24HR in a mini capsule, making it convenient for daily use and gentle on your throat.

What We Like
Easy-to-swallow mini capsules
24-hour heartburn relief
Blocks acid at the source
Delayed-release formula
All-day and all-night protection
#TOP 5

Amazon Basic Care Lansoprazole Delayed Release Capsules

Amazon Basic Care
Original
Amazon Basic Care Lansoprazole Delayed Release Capsules Cover
Amazon Basic Care Lansoprazole Delayed Release Capsules, 15 mg, Proton Pump Inhibitor, Acid Reducer, 24 Hour Heartburn Medicine, 42 Count Pack

Amazon Basic Care Lansoprazole Delayed Release Capsules contain lansoprazole 15 mg, an acid reducer that stops acid production at the source. It is clinically proven to treat frequent heartburn, that painful, burning sensation in the lower chest or throat that occurs when stomach acid backs up. It reduces heartburn by deactivating acid-producing pumps in the stomach lining. You may get complete relief within 24 hours, and it may take 1 to 4 days for full effect. It's gluten-free, sodium-free, and treats frequent heartburn.

What We Like
Contains the active ingredient in Prevacid 24 HR
Clinically proven to treat frequent heartburn
Reduces heartburn by deactivating acid-producing pumps in the stomach lining
#TOP 6

Ohm Omeprazole 20mg Acid Reducer 42 Tablets

Ohm
1147492
Ohm Omeprazole 20mg Acid Reducer 42 Tablets Cover
Ohm Omeprazole 20mg, 42 Delayed-Release Tablets, Acid Reducer for Frequent Heartburn, 24-Hour Relief Heartburn Medicine, Helps Relieve Stomach & Chest Discomfort (6 Weeks of Supply, 42, Count)

The Ohm Omeprazole Heartburn Relief offers a trusted formula with the same active ingredient as Prilosec, helping you manage frequent heartburn that happens two or more days a week. You get up to 24 hours of relief from acid reflux with just one tablet, making it easy to stay comfortable throughout the day. Its delayed-release formula means the omeprazole is gradually released, giving you steady relief for indigestion and stomach discomfort. Each pack includes 42 tablets, enough for three 14-day treatment courses, so you can effectively control your heartburn over time. It may take a few days to feel the full benefits, but it's designed for lasting comfort.

What We Like
Effective heartburn relief
Great value for price
Easy to swallow
Long-lasting results
Works like name brand
#TOP 7

HealthCareAisle Lansoprazole 15 mg

Capsule
HealthCareAisle Lansoprazole 15 mg Cover
HealthCareAisle Lansoprazole 15 mg - 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn

HealthCareAisle Lansoprazole 15 mg is an effective acid reducer that treats frequent heartburn. By inhibiting the proton pumps in the stomach from producing excess acid, this medication provides all-day relief from heartburn for up to 24 hours. Comparable to the national brand Prevacid 24HR, HealthCareAisle Lansoprazole is a reliable choice for managing heartburn. It is recommended to use this product for a 14-day course of treatment, following the provided directions. The full effect may take 1 to 4 days to be noticeable. It is important to note that this medication is not for immediate relief and users should refer to the package label for warnings and other important information.

What We Like
Effective heartburn medicine
Stop heartburn at the source
All-day heartburn relief
#TOP 8

Amazon Basic Care Esomeprazole Magnesium Mini Capsules

Amazon Basic Care
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Amazon Basic Care Esomeprazole Magnesium Mini Capsules Cover
Amazon Basic Care Esomeprazole Magnesium Delayed-Release Mini Capsules, 20 mg, Acid Reducer, 24 Hour Heartburn Medicine, 42 Count

Amazon Mini Capsules are designed to treat frequent heartburn effectively. The esomeprazole 20 mg capsules deactivate acid-producing pumps in your stomach, providing relief from heartburn that occurs 2 or more days a week. These mini capsules, smaller in size than regular ones, offer a 24-hour heartburn treatment. With a 14-day course of treatment, they are clinically proven to reduce acid production at the source. Amazon Mini Capsules are gluten-free and suitable for adults 18 years and older.

What We Like
24-hour heartburn relief
Smaller size capsules
Clinically proven effectiveness
#TOP 9

TIME-CAP LABS Timely Esomeprazole 42 Capsules

TIME-CAP LABS Timely Esomeprazole 42 Capsules Cover
TIME-Cap Labs 42 Capsules Esomeprazole Magnesium 20mg Delayed Release - Acid Reducer & Frequent Heartburn Relief for Adults, Helps with Acid Reflux & Heartburn

Timely Esomeprazole Capsules offer reliable relief from heartburn and acid reflux with just one capsule a day. By targeting the source of stomach acid, this product helps you enjoy daily activities without discomfort. The delayed-release feature ensures that the medication works effectively throughout the day and night, providing lasting comfort. Plus, you won't have to juggle multiple doses, making it a convenient option for busy lifestyles. With results that may take a few days to fully kick in, you can look forward to a more pleasant experience as you tackle your day.

What We Like
24-hour relief
One capsule daily
Delayed-release formula
Cost-effective solution
#TOP 10

Glenmark Esomeprazole Magnesium 20mg Capsules

Glenmark Esomeprazole Magnesium 20mg Capsules Cover
Glenmark Therapeutics Esomeprazole Magnesium USP 20mg, Delayed Release Capsules, Treats Frequent Heartburn, 42 Capsules

Glenmark Esomeprazole 20mg Capsules, a product by Glenmark Therapeutics, are delayed-release capsules containing esomeprazole magnesium, an acid reducer. These capsules inhibit acid production at the source, making them effective in treating frequent heartburn that occurs 2 or more days a week. By taking one capsule every 24 hours for 14 days, you can experience relief from heartburn. It may take 1 to 4 days to feel the full effect of this heartburn treatment.

What We Like
Delayed-Release Capsules
Proven Acid Reducer
Heartburn Treatment
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Which is the best capsule for acidity?

These medications are also good for protecting the esophagus from acid so that esophageal inflammation can heal....They include:. Dexlansoprazole (Dexilant)Esomeprazole (Nexium)Lansoprazole (Prevacid)Omeprazole (Prilosec, Zegerid)Pantoprazole (Protonix)Rabeprazole (Aciphex)

2. What is used of antacid tablet?

Antacids help to treat heartburn (indigestion). They work by neutralizing the stomach acid that causes heartburn. You can buy many antacids without a prescription. Liquid forms work faster, but you may like tablets because they are easy to use.

3. What type of tablet is antacid?

Antacids are over-the-counter (OTC) medications that help neutralize stomach acid. They work differently from other acid reducers such as H2 receptor blockers and proton pump inhibitors (PPIs). Those drugs work by reducing or preventing the secretion of stomach acid.

4. What are the three types of antacids?

Antacids differ from other types of medications that doctors may prescribe for excess acid symptoms. These include proton pump inhibitors (PPIs) and histamine 2 (H2) blockers....Examples of over-the-counter (OTC) antacid brands include:. Alka-Seltzer.Gaviscon.Mylanta.Rolaids.TUMS.

Editor's Notes

During our capsule antacid research, we found 24 capsule antacid products and shortlisted 10 quality products. We collected and analyzed 287,161 customer reviews through our big data system to write the capsule antacids list. We found that most customers choose capsule antacids with an average price of $12.44.

The capsule antacids are available for purchase. We have researched hundreds of brands and picked the top brands of capsule antacids, including Nexium, HealthCareAisle, Ohm, TIME-CAP LABS, INC., Glenmark Therapeutics. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.