Best Antacids for Stomach of 2025

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Antacids are a type of medication that can provide relief from acid reflux, heartburn, and other stomach-related discomforts. These medications work by neutralizing the acid in the stomach, which can help to reduce the burning sensation associated with acid reflux. There are many different types of antacids available on the market, including tablets, liquids, and chews. Some antacids also contain additional ingredients that can help to soothe the stomach and reduce inflammation. Overall, antacids are a safe and effective way to manage stomach-related issues, and they can be purchased over-the-counter without a prescription.
At a Glance: Our Top Picks
Top 10 Antacids for Stomach
GoodSense Omeprazole Delayed Release Tablets 20 mg
GoodSense Omeprazole is an acid reducer that treats frequent heartburn occurring two or more times a week. The 14-day course of heartburn treatment deactivates the pumps in the stomach lining to inhibit acid production at the source. It is taken once every 24 hours for 14 days and does not provide immediate relief for heartburn. Heartburn tips are provided to avoid certain foods or drinks that trigger heartburn.
Pepcid AC Heartburn Relief Tablets, 75 Ct
Pepcid AC Heartburn Relief Tablets, with 20mg of famotidine, prevent and relieve heartburn caused by acid indigestion and sour stomach. Each tablet provides all-day or all-night acid control. Take a tablet before meals to control acid. Keep a pack handy at home or work for quick relief. Adults and children 12+ can take 1 tablet with water, up to 2 tablets in 24 hours.
Amazon Basic Care Maximum Strength Famotidine Tablets 20 mg
Amazon Basic Care Famotidine Tablets 20 mg contain an active ingredient that reduces acid to relieve heartburn and prevent it from occurring. It takes 10 to 60 minutes to work before consuming foods and beverages that cause acid indigestion. You only need one tablet, and it works for up to 12 hours. It is gluten-free and suitable for adults and children aged 12 years and older.
Amazon Basic Care Omeprazole Tablets
If you suffer from frequent heartburn, Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg can be your solution. The active ingredient, omeprazole 20mg, is a Proton Pump Inhibitor that deactivates pumps in the stomach lining to inhibit acid production at the source, providing 14 days of heartburn relief. Not only does it treat frequent heartburn that occurs two or more times a week, but it also has heartburn tips to avoid triggering it. Avoid eating late at night or before bedtime, including certain foods or drinks such as chocolate, spicy, fatty, and fried foods, caffeine, and alcohol.
Berkley Jensen Extra Strength Antacid Tablets
Berkley Jensen Antacid Tablets provide quick relief from heartburn and indigestion, especially after enjoying a hearty or spicy meal. Each chewable tablet contains 750mg of Calcium Carbonate, which effectively neutralizes stomach acid, helping you feel comfortable again. These antacids are gluten and dairy-free, making them suitable for those with dietary restrictions. Plus, with a delicious berry flavor, taking these tablets feels more like enjoying a treat than taking medicine, making relief enjoyable and easy. With 200 tablets in a pack, you’ll always have a supply on hand for any discomfort that arises.
TUMS Chewy Bites Antacid Tablets - Assorted Berries (60 Count)
TUMS Chewy Bites Antacid Tablets are the ultimate solution for those who suffer from heartburn, acid indigestion, sour stomach, and upset stomach. The 60-count bottle includes chewable tablets in assorted berry flavors, with a tasty outer shell and soft center. These calcium carbonate tablets work instantly to neutralize acid and provide fast and powerful multi-symptom relief. This heartburn medicine is gluten-free and comes in a compact, resealable bottle that's easy to carry wherever you go. TUMS is the number 1 doctor-recommended antacid brand, providing trusted heartburn relief for 90 years.
HealthCareAisle Omeprazole 20mg Capsules
HealthCareAisle Omeprazole 20mg Capsules are an effective medicine for treating frequent heartburn. The capsules contain an acid reducer that stops heartburn by inhibiting the proton pumps in the stomach from producing excess acid. You can expect relief for up to 24 hours with just one capsule per day, and it is comparable to the national brand, Prilosec OTC. However, it is important to note that the capsules are not for immediate relief and may take 1 to 4 days for the full effect to take place.
Alka-Seltzer Extra Strength Heartburn Relief Chews
Alka-Seltzer Extra Strength Heartburn Relief Chews offers fast and multi-symptom relief for heartburn, acid indigestion, and upset stomach. The assorted fruit-flavored tablets start neutralizing acid in seconds, providing a great taste. The brand, Alka-Seltzer, is a trusted name in acid indigestion medicine since 1931.
Amazon Basic Care Antacid Fruit Chews
Get fast-acting relief for heartburn, acid indigestion, upset and sour stomach with Amazon Basic Care Extra Strength Antacid Fruit Chews. With 750mg of calcium carbonate, this chewy, not chalky product comes in a delicious assortment of lemon, orange, and strawberry flavors. The easy-to-open flip cap bottle makes it convenient for adults and children 12 years and up to take 1-2 chewable tablets every 2-4 hours as needed. And, the best part? This product offers the same benefits as the name brand at a lower cost to consumers.
Alka-Seltzer Lemon Lime Heartburn Relief Tablets
Alka-Seltzer Heartburn Relief offers a delicious lemon lime option for quickly easing your discomfort. These effervescent tablets effectively neutralize excess stomach acid, providing rapid relief from heartburn, sour stomach, acid indigestion, and upset stomach. You’ll enjoy the fizzy experience as you dissolve the tablets in water, making it a fun way to feel better. Plus, with convenient sachets, you can take this relief wherever you go, ensuring you have access to soothing comfort anytime you need it. Trust in a brand that has been a reliable choice for over 90 years.
Frequently Asked Questions (FAQs)
1. Are antacids good for stomach?
Antacids can often relieve symptoms of excess stomach acid. However, sometimes these symptoms mean you have a more serious condition. It's important that you know how to recognize these conditions and how to respond to them. An upset stomach could actually be gastroesophageal reflux disease (GERD) or a peptic ulcer.
2. What is the safest antacid to take?
FDA declares Pepcid, Nexium and others free of NDMA. The bad news for heartburn sufferers, of course, is that Zantac and its ranitidine generics have, perhaps for years, contained a suspected carcinogen without the FDA knowing it.
3. What antacid is good for stomach pain?
Tums is an affordable, effective option for treating an upset stomach. Chewable Tums tablets start working within five minutes and can be taken as needed. Tums should only be used for mild, occasional heartburn and indigestion.
During our antacid for stomach research, we found 24 antacid for stomach products and shortlisted 10 quality products. We collected and analyzed 637,063 customer reviews through our big data system to write the antacids for stomach list. We found that most customers choose antacids for stomach with an average price of $11.86.
The antacids for stomach are available for purchase. We have researched hundreds of brands and picked the top brands of antacids for stomach, including GoodSense, Pepcid, berkley jensen, TUMS, HealthCareAisle. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.