Best Spray Weed Killers of 2026

Steven Taylor Avatar
Steven Taylor
Last Updated: Jan 15, 2026

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Spray weed killers are a popular choice for gardeners and homeowners looking to maintain a weed-free lawn or garden. These products come in a variety of formulas, including selective and non-selective options. Selective weed killers target specific types of weeds while leaving desirable plants unharmed, while non-selective options kill all vegetation they come into contact with. Some spray weed killers are formulated to provide quick results, while others offer longer-lasting control. It is important to follow the instructions carefully when using these products to ensure safety and effectiveness.

At a Glance: Our Top Picks

Roundup Weed & Grass Killer₄ with Pump 'N Go 2 Sprayer Cover #TOP 1
Roundup Weed & Grass Killer₄ with Pump 'N Go 2 Sprayer
ftb score rating icon 9.9
Ortho WeedClear Lawn Weed Killer Ready to Spray Cover #TOP 2
Ortho WeedClear Lawn Weed Killer Ready to Spray
ftb score rating icon 9.8
Spectracide Weed and Grass Killer with AccuShot Sprayer Cover #TOP 3
Spectracide Weed and Grass Killer with AccuShot Sprayer
ftb score rating icon 9.6

Top 10 Spray Weed Killers

Roundup Weed & Grass Killer₄ with Pump 'N Go 2 Sprayer

5375304
1.33 gal
Roundup Weed & Grass Killer₄ with Pump 'N Go 2 Sprayer Cover
Roundup Weed and Grass Killer₄ with Pump 'N Go 2 Sprayer, Use in and Around Flower Beds, Trees & More, 1.33 gal.

Roundup Weed Killer is a powerful solution that eliminates tough weeds and grasses down to the root. It works quickly, becoming rainproof in just 30 minutes and showing visible results within hours. You can plant new vegetation within 1 to 30 days after applying. This product is suitable for use in various areas like flower beds, around trees, on walkways, driveways, fences, and foundations. The Pump ‘N Go 2 Sprayer makes application easier with an extendable wand for precise spraying without the need to bend over.

What We Like
Fast-acting weed control
Easy application and use
Highly effective on tough weeds
Good coverage and value
Convenient Pump 'N Go sprayer

Ortho WeedClear Lawn Weed Killer Ready to Spray

447805
32 fl oz
Ortho WeedClear Lawn Weed Killer Ready to Spray Cover
Ortho WeedClear Lawn Weed Killer Ready-To-Spray, Kills Crabgrass, Dandelion and Clover, 32 oz.

Ortho WeedClear Lawn Weed Killer Ready to Spray is a ready-to-use weed killer that kills all major broadleaf weeds, including dandelion, chickweed and crabgrass. It is rainproof in 1 hour and delivers visible results in hours, after just one application. It is suitable for grasses including Bermudagrass, Buffalograss, Tall Fescue, Fine Fescues, Kentucky Bluegrass, Ryegrass, and Zoysiagrass, and can treat up to 5,000 sq. ft. with a garden hose. Customers have found it to be effective on a variety of broadleaf weeds, though it may require multiple applications for full eradication.

What We Like
Kills weeds without harming lawn
Rainproof in 1 hour
Kills over 200 types of weeds
Suitable for multiple lawn varieties
Treats up to 5,000 sq. ft.

Spectracide Weed and Grass Killer with AccuShot Sprayer

HG-96370
Spectracide Weed and Grass Killer with AccuShot Sprayer Cover
1 gal Ready-to-Use Grass and Weed Killer

Take command of your lawn and garden with Spectracide Weed and Grass Killer with AccuShot Sprayer. This non-selective weed and grass killer is perfect for spot treatment of weeds and grasses on patios, walkways, driveways, and around flowers, shrubs, trees, fences, and foundations. With visible results in as fast as 3 hours and rainfast in just 15 minutes, you can replant new flowers, trees, and shrubs in the treated area after just 1 day. The AccuShot continuous power sprayer with an extendable wand makes it easy to target the weeds or grass you want to kill. Plus, with a money-back guarantee, you can trust that this product will deliver the results you want.

What We Like
Very easy to use
Fast-acting weed and grass control
No mixing or pumping required
Convenient battery-operated dispenser
Effective for small and large areas

Ortho GroundClear Weed & Grass Killer

4613264
Brown/A
1-Pack
Ortho GroundClear Weed & Grass Killer Cover
Ortho GroundClear Weed and Grass Killer with Comfort Wand, Kills Dandelions, Chickweed, Crabgrass, Moss and More in Patios and Landscapes, OMRI Listed, 1 gal.

Ortho GroundClear Weed & Grass Killer Ready-to-Use is a grass weed killer spray that works on all types of weeds and grasses. It acts on contact and you can see results in 15 minutes. It is rainproof in 2 hours and can be used on hardscapes, landscape beds, and around vegetable gardens. Customers have found it to be easy to use and effective in killing weeds.

What We Like
Effective weed and grass killer
Fast visible results
Easy electric wand application
Organic active ingredient
Ready-to-use formula

Natural Elements Weed Killer

1 Gallon
Natural Elements Weed Killer Cover
Natural Elements Weed Killer | Pet Safe, Safe Around Children | Natural Herbicide (1 Gallon)

Natural Elements Weed Killer is a pet-safe, all-natural herbicide derived from vinegar. It is effective on most broadleaf weeds and grasses, and is ready to use with no hassle or mixing required. Customers have praised its quick-acting results and its safety around pets and children. However, some customers have noted that the price is high and that it does not come with a sprayer.

What We Like
Non-toxic natural ingredients
Safe for kids and pets
Fast visible results
Effective weed control
No harsh chemical smell
#TOP 6

Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer

5478305
Wand
Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer Cover
Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Comfort Wand, Kills & Prevents for up to 1 Year, 1 gal.

Roundup Weed Killer Plus provides long-lasting weed protection for up to 12 months. This product kills and prevents various tough weeds and grasses, including clover, dandelion, crabgrass, and poison ivy. It is rainproof within 30 minutes, delivering quick visible results. Use it to eliminate existing weeds and stop new ones from growing in non-lawn areas like driveways, sidewalks, and patios. The Comfort Wand with continuous spray ensures easy application without straining your hands.

What We Like
Rapid weed elimination
Long-lasting results
Easy application
No harm to other plants
Large area coverage

Ortho GroundClear Year Long Vegetation Killer2 Concentrate

Miracle-Gro - 4657110
1 gal.
Ortho GroundClear Year Long Vegetation Killer2 Concentrate Cover
Ortho GroundClear Year Long Vegetation Killer2 Concentrate, Kills and Prevents Weeds Up to 12 Months, 1 gal.

Ortho GroundClear Weed Killer is designed to keep areas free of unwanted plants for up to a year, making it ideal for places like driveways, sidewalks, and gravel spots where you want no growth. This fast-acting concentrate starts working right away and kills weeds down to the root, so you get effective and lasting results. It not only removes existing weeds and grasses but also prevents new ones from growing back for a full year, saving you time and effort. You can easily apply it with a tank hose sprayer by mixing 24 ounces of the concentrate with one gallon of water, covering up to 300 square feet efficiently.

What We Like
Long-lasting weed control
Fast-acting results
Highly concentrated formula
Effective on multiple weed types
Easy to use
#TOP 8

Spruce Weed Killer Refill 64 Oz

SPR-0015
Spruce Weed Killer Refill 64 Oz Cover
Spruce Weed Killer Refill - Versatile Weed & Grass Killer₂ for Flower Beds, Driveways & Mulch Beds - No Pour, No Mix, No Mess Refill - Kills Dandelions, Crabgrass & More (64 Oz)

The Spruce Weed Killer is an effective solution for tackling weeds in your garden and yard. With its worry-free formula made from water and essential oils, you can safely use it around family and pets. You’ll see visible results within just one hour as it quickly dehydrates and kills various weeds, including dandelions and crabgrass. This product is perfect for treating mulch beds, driveways, and walkways, ensuring your outdoor spaces look their best. Plus, one 64 oz bottle can handle up to 400 weeds, making it a convenient choice for your weed control needs.

What We Like
Pet and people safe
Easy-to-use sprayer design
Minimal waste, efficient container
Pleasant or mild scent
Fast action on many weeds

Liquid Harvest Lazer Blue

00125
Blue
8 Fl Oz
Liquid Harvest Lazer Blue Cover
Liquid Harvest Lazer Blue Concentrated Spray Pattern Indicator 8 Ounces Perfect Weed Dye, Herbicide Fertilizer Marking Turf Mark and Marker

Liquid Harvest Lazer Blue is a concentrated spray pattern indicator that helps prevent over-application, detects product drift, and is easy to use without additional equipment. It is versatile and improves application accuracy by providing a visual guide. By using Lazer Blue, you can save time and money while optimizing your product usage.

What We Like
Prevents over-application
Detects product drift
Easy to use
#TOP 10

Bonide 2746 Stump & Vine Killer Concentrate

2746
Concentrate
Bonide 2746 Stump & Vine Killer Concentrate Cover
Stump-Out Stump & Vine Killer, 8 oz Concentrate with Applicator, Fast Acting Home Tree Stump Removal

The Bonide Stump & Vine Killer is a powerful weed killer that not only controls woody plants and vines but also works as a stump killer. With its easy application, you can eliminate undesirable woody vines, plants, and broadleaf weeds without harming your turf. Use it undiluted to kill stumps and prevent sprouting, or apply it as a foliar spray using a hose-end or tank sprayer. This versatile product is perfect for outdoor use around homes, cabins, fences, and walkways. The Bonide Stump & Vine Killer works quickly, delivering visible results within 1-6 weeks. Say goodbye to stubborn weeds and unwanted stumps with this effective and convenient solution.

What We Like
Controls woody plants and vines
Works as a stump killer
Easy application
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Can you spray weed killer in your garden?

If you must spray, there are some new, citrus-based natural weed killers, such as Avenger Organic Weed Killer, that are totally safe for use in the garden. Citrus-based weed killers are highly effective when sprayed on young, tender weeds popping up in your vegetable garden.

2. When Should I spray my lawn for weed killer?

When is the best time to apply a broadleaf herbicide to the lawn? Fall (mid-September to early November) is the best time to control perennial broadleaf weeds in the lawn with broadleaf herbicides.

3. What weed killer kills everything?

Glyphosate is systemic, will kill grass and pretty much every other plant it touches. Used to kill annuals, perennials, woody perennials and tree stumps. Glyphosate is used with 85% of GM crops grown globally.

Editor's Notes

During our spray weed killer research, we found 24 spray weed killer products and shortlisted 10 quality products. We collected and analyzed 336,147 customer reviews through our big data system to write the spray weed killers list. We found that most customers choose spray weed killers with an average price of $20.44.

The spray weed killers are available for purchase. We have researched hundreds of brands and picked the top brands of spray weed killers, including Roundup, Ortho, Spectracide, Natural Elements, Spruce. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Steven Taylor Avatar

Steven Taylor grew up in a small town called Beaufort in South Carolina and his passion for building and woodworking has led him to master the latest garden gadgets. He always holds every chance to patch up or sand down his beloved garden. There are various novel technologies in his articles.