Best Southern Weed Killers of 2025

Steven Taylor Avatar
Steven Taylor
Last Updated: Jan 8, 2025

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Southern Weed Killers is a reliable brand that offers effective solutions for weed control. Their products are specially formulated to target various types of weeds commonly found in the Southern United States. From broadleaf weeds to grassy weeds, Southern Weed Killers have got you covered. Their herbicides are designed to be easy to use and can be applied to lawns, gardens, and other outdoor areas. With Southern Weed Killers, you can have a weed-free landscape without the hassle of manual weeding. Trust in their expertise and experience to keep your outdoor spaces looking their best.

At a Glance: Our Top Picks

BioAdvanced Season Long Lawn Weed Killer + Preventer for Southern Lawns 10 LB Granules Cover #TOP 1
BioAdvanced Season Long Lawn Weed Killer + Preventer for Southern Lawns 10 LB Granules
ftb score rating icon 9.8
Southern Ag Amine 2,4-D WEED KILLER Cover #TOP 2
Southern Ag Amine 2,4-D WEED KILLER
ftb score rating icon 9.7
Southern Ag Atrazine St. Augustine Weed Killer Cover #TOP 3
Southern Ag Atrazine St. Augustine Weed Killer
ftb score rating icon 9.5

Top 10 Southern Weed Killers

BioAdvanced Season Long Lawn Weed Killer + Preventer for Southern Lawns 10 LB Granules

820060B
BioAdvanced Season Long Lawn Weed Killer + Preventer for Southern Lawns 10 LB Granules Cover
BioAdvanced Season Long Lawn Weed Killer + Preventer for Southern Lawns 10 LB Granules, 4,000 SQ FT

The BioAdvanced Weed Killer + Preventer is a highly effective solution for maintaining a weed-free lawn. With its ability to kill listed broadleaf weeds like Dandelion, Clover, Chickweed, Dollarweed, and Henbit for up to 6 months, this product ensures a long-lasting control over unwanted vegetation. Additionally, it prevents the growth of grassy and listed broadleaf weeds such as Crabgrass, Annual Bluegrass, Common Dandelion, Goosegrass, and Spurge for up to 6 months. This makes it an ideal choice for those who want to keep their lawns free from these common weeds. The BioAdvanced Weed Killer + Preventer is specially formulated for use on southern lawns, treating up to 4,000 square feet of turf, including all varieties of St. Augustinegrass and Floratam. Its season-long weed control feature eliminates the need for multiple applications, providing convenience and peace of mind to users. With over 50 listed lawn weeds targeted, this product is a reliable and efficient solution for maintaining a beautiful, weed-free lawn.

What We Like
Long-lasting weed control
Prevents the growth of grassy and broadleaf weeds
Convenient and time-saving

Southern Ag Amine 2,4-D WEED KILLER

00203-1
White
32oz - Quart
Southern Ag Amine 2,4-D WEED KILLER Cover
Southern Ag Amine 2,4-D WEED KILLER, 32oz - Quart

Southern Ag Amine 2,4-D WEED KILLER is a selective broadleaf weed control for use in various areas, including pastures, lawns, golf courses, and parks. It is designed to kill weeds while leaving the grass or other plants unharmed.

What We Like
Selective broadleaf weed control
Suitable for use in different areas
Effective for killing weeds
#TOP 3

Southern Ag Atrazine St. Augustine Weed Killer

006130
Light Tan
Southern Ag Atrazine St. Augustine Weed Killer Cover
Southern Ag 006130 Atrazine St. Augustine Weed Killer 32oz Specialty Herbicide, Light Tan

The Southern Ag Atrazine St. Augustine Weed Killer is a highly effective specialty herbicide that controls weeds in St. Augustine and Centipede Grasses. With one quart treating 3,720 sq ft, it is perfect for large lawn areas. The lightweight package makes it easy to handle and store, with dimensions of 5.842 L x 19.177 H x 12.954 W (centimeters).

What We Like
Highly effective in controlling weeds in St. Augustine and Centipede Grasses
Covers a large area of 3,720 sq ft per quart
Lightweight and easy to handle and store
#TOP 4

Roundup for Lawns Ready-To-Use (Southern)

5012520
Roundup for Lawns Ready-To-Use (Southern) Cover
Roundup for Lawns₄ Ready-To-Use (Southern) - All-in-One Weed Killer for Lawns, Extended Reach Wand, 1 gal.

Roundup Weed Killer for Lawns is a convenient solution for Southern grasses. It effectively kills 93 types of weeds like dollarweed, dandelion, and clover while preserving your lawn. With immediate action and rainproof in 4 hours, you can expect quick results without harming your grass. The extended reach wand makes application easy and precise, ensuring thorough coverage. This ready-to-use weed killer is perfect for busy homeowners looking for a hassle-free way to maintain a weed-free lawn.

What We Like
Preserves lawn
Effective on 93 weeds
Immediate action
#TOP 5

Scotts WeedEx Southern Weed Killer

49802
12.5 lb
Scotts WeedEx Southern Weed Killer Cover
Scotts WeedEx Southern, Weed Killer Controls Dollarweed, Clover, and More, Southern Lawn Care, 4,000 sq. ft., 12.5 lbs.

Scotts WeedEx Southern is an effective weed killer designed to tackle tough weeds like dollarweed and clover throughout the growing season. You can apply this product when both your grass and weeds are actively growing, ensuring maximum effectiveness. After application, it's essential to water the area immediately, which helps the formula penetrate the weeds' roots. This weed killer is specifically formulated for Southern grass types, including St. Augustinegrass and Centipedegrass, making it an ideal choice for homeowners in warmer climates. With one 12.5 lb. bag covering up to 4,000 sq. ft., it offers great value for maintaining a healthy lawn.

What We Like
Effective against tough weeds
Designed for Southern grasses
Covers large lawn areas
Easy application process
#TOP 6

Southern Ag 13503 Lawn Weed Killer with TRIMEC 32oz Herbicide

13503
Brown
32oz
Southern Ag 13503 Lawn Weed Killer with TRIMEC 32oz Herbicide Cover
Southern Ag 13503 Lawn Weed Killer with TRIMEC 32oz Herbicide, Brown

The Southern Ag 13503 Lawn Weed Killer with TRIMEC 32oz Herbicide is a potent weed killer that can be used on nine different types of turf. It is capable of controlling a wide range of lawn weeds and contains a patented combination of three proven weed killers. The product comes with directions for use in both conventional and hose end sprayers, and it is recommended to use a surfactant for herbicide to increase performance.

What We Like
Can be used on nine different types of turf
Controls a wide range of lawn weeds
Contains a patented combination of three proven weed killers
#TOP 7

Roundup For Lawns Concentrate (Southern)

5012307
Roundup For Lawns Concentrate (Southern) Cover
Roundup For Lawns₅ Concentrate (Southern) - All-in-One Weed Killer for Lawns, 32 oz.

Roundup Weed Killer for Lawns is a powerful solution that targets weeds while keeping your lawn safe when used correctly. With the capability to eliminate 93 types of weeds like dandelion and clover, this product is perfect for Southern grasses such as St. Augustine and Bermudagrass. It starts working immediately, and within 4 hours, it becomes rainproof. The concentrate formula, which can cover up to 6,000 sq. ft., is effortless to mix, making weed control a breeze for you.

What We Like
Safe for lawns
Effective on 93 weed types
Quick results
#TOP 8

Scotts Turf Builder Bonus S Southern Weed & Feed2

33020
10,000 sq. ft.
Scotts Turf Builder Bonus S Southern Weed & Feed2 Cover
Scotts Turf Builder Bonus S Southern Weed & Feed2, Weed Killer and Lawn Fertilizer, 10,000 sq. ft., 34.48 lbs.

Scotts Weed & Feed2 is a powerful weed killer and lawn fertilizer specifically designed for Southern lawns. It effectively kills existing weeds and prevents future weed growth, while also providing essential nutrients to nourish the grass and promote strong root development. This product is perfect for St. Augustinegrass, Centipedegrass, Zoysiagrass, and Carpetgrass. Simply apply it to a dry lawn during active grass and weed growth, and then water it in immediately. With Scotts Weed & Feed2, you can say goodbye to pesky weeds and hello to a lush, healthy lawn.

What We Like
Kills existing weeds
Prevents future weed growth
Promotes strong root development
#TOP 9

Southern Ag Atrazine St. Augustine Grass Weed Killer, 1 Gallon

00614
1 Gallon
Southern Ag Atrazine St. Augustine Grass Weed Killer, 1 Gallon Cover
Southern Ag Atrazine St. Augustine Grass Weed Killer, 1 Gallon

Southern Ag Atrazine St. Augustine Grass Weed Killer is a powerful weed killer that eradicates many broadleaf weeds and crabgrass. It can also be used in centipede grass. In addition to controlling emerged weeds, it can also prevent weeds from seed.

What We Like
Effective in killing many broadleaf weeds and crabgrass
Suitable for use in centipede grass
Controls emerged weeds and prevents weeds from seed
#TOP 10

Southern Ag Lawn Weed Killer with Trimec Herbicide

13504
Southern Ag Lawn Weed Killer with Trimec Herbicide Cover
Southern Ag Lawn Weed Killer with Trimec Herbicide, 128oz - 1 Gallon 13504

The Southern Ag Lawn Weed Killer is a powerful weed control solution suitable for use on 9 different types of turf. It is designed to effectively control a wide range of lawn weeds, thanks to its patented combination of three proven weed killers. The product can be used in both conventional and hose end sprayers, making it convenient and versatile to use.

What We Like
Controls a wide range of lawn weeds
Patented combination of 3 proven weed killers
Can be used on 9 different turf types
Buying Guide Image

Frequently Asked Questions (FAQs)

1. How do you kill weeds in Southern grass?

For killing weeds in Southern grass, Roundup For Lawns4 is a recommended option. It is a tough weed killer specifically designed for Southern grasses. This product effectively eliminates 93 types of weeds, including dollarweed, dandelion, clover, and yellow nutsedge, while preserving the health of the grass.

2. What weed killer kills everything but grass?

SedgeHammer® Herbicide is a suitable weed killer that targets nutsedge weeds without harming the grass. It comes in a Water Dispersible Granule (WDG) form and needs to be mixed with water for application. While it may take up to 21 days to show results, it is an effective option for controlling nutsedge without damaging the grass.

3. Is bleach or vinegar better for weeds?

Bleach is a potent weed killer that can effectively eliminate mature weeds and prevent new ones from growing. Unlike vinegar, bleach remains in the soil, providing longer-lasting weed control. However, it's important to note that bleach is a more noxious substance compared to vinegar.

4. Does vinegar kill weeds permanently?

Vinegar, being acidic, can kill most broadleaf weeds. However, it primarily affects the leaves and may not reach the root system, leading to potential regrowth. For more long-lasting results, a mixture of 1 cup of table salt with 1 gallon of vinegar can be used, as the salt helps dry out the weed's root system.

5. What kills weeds permanently but not grass?

To kill weeds permanently without harming grass, it is recommended to use a selective herbicide. Selective herbicides target specific weeds while leaving the grass unharmed. It is important to carefully read and follow product labels to ensure proper usage. Non-selective herbicides, on the other hand, can kill any plant they come in contact with, including grass.

6. How do I permanently get rid of weeds in my gravel driveway?

Rock salt can be an effective and natural weed killer for gravel driveways. Simply sprinkle rock salt on the areas with weeds, and over time, it will kill them. However, it's important to note that rock salt can also harm nearby plants, so it should be used with caution and only in areas where you want to eliminate vegetation.

Editor's Notes

During our southern weed killer research, we found 24 southern weed killer products and shortlisted 10 quality products. We collected and analyzed 62,337 customer reviews through our big data system to write the southern weed killers list. We found that most customers choose southern weed killers with an average price of $18.98.

The southern weed killers are available for purchase. We have researched hundreds of brands and picked the top brands of southern weed killers, including BioAdvanced, Southern Ag, Roundup, Scotts. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Steven Taylor Avatar

Steven Taylor grew up in a small town called Beaufort in South Carolina and his passion for building and woodworking has led him to master the latest garden gadgets. He always holds every chance to patch up or sand down his beloved garden. There are various novel technologies in his articles.