Best Southern Weed Killers of 2026

Steven Taylor Avatar
Steven Taylor
Last Updated: Jan 15, 2026

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Southern Weed Killers is a reliable brand that offers effective solutions for weed control. Their products are specially formulated to target various types of weeds commonly found in the Southern United States. From broadleaf weeds to grassy weeds, Southern Weed Killers have got you covered. Their herbicides are designed to be easy to use and can be applied to lawns, gardens, and other outdoor areas. With Southern Weed Killers, you can have a weed-free landscape without the hassle of manual weeding. Trust in their expertise and experience to keep your outdoor spaces looking their best.

At a Glance: Our Top Picks

Southern Ag Crossbow Specialty Herbicide 128oz Cover #TOP 1
Southern Ag Crossbow Specialty Herbicide 128oz
ftb score rating icon 9.8
Southern Ag Atrazine & Celsius Weed Control Combo Cover #TOP 2
Southern Ag Atrazine & Celsius Weed Control Combo
ftb score rating icon 9.7
Ortho WeedClear Lawn Weed Killer with Comfort Wand Cover #TOP 3
Ortho WeedClear Lawn Weed Killer with Comfort Wand
ftb score rating icon 9.5

Top 10 Southern Weed Killers

#TOP 1

Southern Ag Crossbow Specialty Herbicide 128oz

100520254
Reddish Brown
1 gallon
Southern Ag Crossbow Specialty Herbicide 128oz Cover
Southern Ag Crossbow Specialty Herbicide Low Volatile Weed & Brush Herbicide, 128oz - Gallon

The Southern Ag Crossbow Herbicide is a powerful solution designed to help you manage unwanted trees, brush, and broadleaf weeds in your yard or property. It’s effective against both annual and perennial weeds, making it a versatile choice for long-term weed control. With one gallon of this herbicide, you can create up to 96 gallons of spray solution, giving you plenty of coverage for larger areas. The active ingredients, Garlon and 2,4-D, work together to target tough vegetation, ensuring you get reliable results with less effort.

What We Like
Effective on trees and brush
Controls broadleaf weeds
High coverage per gallon
Contains proven active ingredients
#TOP 2

Southern Ag Atrazine & Celsius Weed Control Combo

Southern Ag Atrazine & Celsius Weed Control Combo Cover
Southern Ag Atrazine St. Augustine Weed Killer 32oz + Celsius WG 0.226oz Weed Control for St. Augustine & Centipede Grasses

The Southern Ag Weed Control combines two powerful solutions to help you maintain a healthy lawn. It kills broadleaf weeds in St. Augustine and Centipede grasses, covering over 3,700 square feet, so you can protect large areas efficiently. The Celsius part of the product targets more than 120 types of weeds, including stubborn dandelions, while being safe for St. Augustine grass, ensuring your lawn stays healthy. Atrazine works to suppress crabgrass, preventing it from taking over your yard. Plus, Celsius is a fast-acting foliar herbicide designed specifically for warm-season grasses, giving you quick and effective weed control. The easy mix packet means no measuring is needed, making application simple and hassle-free.

What We Like
Broadleaf weed control
Safe for St. Augustine grass
Crabgrass suppression
Fast-acting herbicide
Easy mix packet
#TOP 3

Ortho WeedClear Lawn Weed Killer with Comfort Wand

40 lb.
Ortho WeedClear Lawn Weed Killer with Comfort Wand Cover
Ortho WeedClear Lawn Weed Killer Ready-to-Use with Comfort Wand with Refill for Southern Lawns

The Ortho WeedClear Lawn Killer is designed to help you get rid of common lawn weeds like dollarweed, dandelions, clover, and chickweed quickly and effectively. You can expect to see results in just a few hours, saving you time and effort. This product targets weeds down to their roots, helping prevent them from coming back. Plus, when used as directed, it’s safe for your lawn grass, so you don’t have to worry about damaging the healthy areas of your yard. It’s a convenient solution for maintaining a clean, green lawn without the hassle.

What We Like
Effective on common weeds
Fast-acting results
Root-level weed control
Safe for lawn grass
#TOP 4

BioAdvanced Season Long Lawn Weed Killer Concentrate

820187B
32 floz
BioAdvanced Season Long Lawn Weed Killer Concentrate Cover
BioAdvanced Season Long Lawn Weed Killer, Concentrate, 32oz

The BioAdvanced Lawn Weed Killer is designed to help you maintain a clean and healthy lawn with ease. It effectively removes common weeds like dandelions, clover, and chickweed, so you don’t have to worry about unsightly patches. The product also prevents new weeds from growing for up to four months, saving you time on constant treatments. Suitable for most northern and southern grass types, you can confidently use it on your lawn without damage. Plus, it tackles nutsedge, a tough and persistent weed, giving you comprehensive control over your yard’s appearance.

What We Like
Effective on common lawn weeds
Prevents weed growth up to 4 months
Safe for most turf types
Controls and prevents nutsedge
#TOP 5

Gordon's Amine 400 2,4-D Weed Killer & Southern Ag Surfactant

GORDON'S
Gordon's Amine 400 2,4-D Weed Killer & Southern Ag Surfactant Cover
Gordon's Amine 400 2,4-D Weed Killer 1 Gallon and Southern Ag Surfactant for Herbicides 128oz

The Gordon's 2,4-D Weed Killer is a powerful solution designed to help you tackle stubborn lawn weeds like dandelions and clover by targeting them right down to the roots. With one gallon of concentrate, you can create up to 512 gallons of ready-to-use weed control, covering a large area of up to 16,000 square feet, making it cost-effective and convenient. The included Southern Ag surfactant enhances the effectiveness of the weed killer by improving spray coverage and helping the herbicide penetrate the plants better. It also reduces water surface tension, ensuring the spray spreads evenly and absorbs efficiently for more reliable results in your lawn care.

What We Like
Large coverage area
Effective on tough weeds
Improved spray penetration
Enhanced herbicide absorption
#TOP 6

PBI/GORDON Trimec Lawn Weed Killer & Southern Ag Surfactant

PBI/GORDON Trimec Lawn Weed Killer & Southern Ag Surfactant Cover
PBI/GORDON Trimec Lawn Weed Killer, one Gallon & Southern Ag Surfactant for Herbicides Non-Ionic, 128oz - 1 Gallon

The PBI/GORDON Trimec Weed Killer is designed to help you eliminate tough lawn weeds effectively. It works best on cool-season grasses, making it a great choice if your lawn includes these types. The product comes in a convenient one-gallon size, giving you enough supply to cover a large area without frequent refills. Plus, it’s ready to use right out of the container, so you don’t have to worry about any complicated setup. This makes the PBI/GORDON Trimec Weed Killer a simple and efficient solution for maintaining a healthy, weed-free lawn.

What We Like
Kills tough weeds
Works on cool-season grasses
One-gallon size
No assembly needed
#TOP 7

Southern Ag Brush Killer 8.8% Triclopyr with Surfactant 1 Gallon Bundle

Southern Ag Brush Killer 8.8% Triclopyr with Surfactant 1 Gallon Bundle Cover
Southern Ag Brush Killer 8.8% Triclopyr 1 Gallon and Surfactant for Herbicides Non-Ionic 128oz 1 Gallon Bundle

The Southern Ag Brush Killer Bundle is designed to help you tackle tough plants like brazilian pepper trees with its 8.8% Triclopyr formula. This powerful herbicide prevents unwanted regrowth by stopping sprouting on tree stumps, making your clearing tasks easier. Included in the bundle is a 128 oz bottle of surfactant, which helps the herbicide spread evenly and penetrate plants better. By reducing the water's surface tension, the surfactant ensures the herbicide covers more area uniformly, so you get better results with less effort. Just mix 1 teaspoon of surfactant per gallon of brush killer for best performance.

What We Like
Effective on tough plants
Prevents stump regrowth
Includes surfactant for better coverage
Improves herbicide penetration
#TOP 8

Roundup for Lawns Ready-To-Use (Southern)

5012520
Roundup for Lawns Ready-To-Use (Southern) Cover
Roundup for Lawns₄ Ready-to-Use (Southern) - All-in-One Weed Killer for Lawns, Extended Reach Wand, 1 gal.

Roundup Weed Killer for Lawns is a convenient solution for Southern grasses. It effectively kills 93 types of weeds like dollarweed, dandelion, and clover while preserving your lawn. With immediate action and rainproof in 4 hours, you can expect quick results without harming your grass. The extended reach wand makes application easy and precise, ensuring thorough coverage. This ready-to-use weed killer is perfect for busy homeowners looking for a hassle-free way to maintain a weed-free lawn.

What We Like
Preserves lawn
Effective on 93 weeds
Immediate action
#TOP 9

Revolver Herbicide 1 Quart & Southern Ag Surfactant 1 Gallon

Revolver
Revolver Herbicide 1 Quart & Southern Ag Surfactant 1 Gallon Cover
Revolver Herbicide, 1 Quart & Southern Ag Surfactant for Herbicides Non-Ionic, 128oz - 1 Gallon

The Revolver Herbicide & Surfactant offers effective control of cool-season grasses in warm-season lawns, helping you maintain a healthy turf. It targets tough weeds like goosegrass and suppresses dallisgrass, providing a different mode of action to help prevent herbicide resistance. You can confidently use it on bermudagrass greens thanks to its specific labeling. Plus, the herbicide is easy to mix and apply, with low usage rates that make it a cost-effective choice for your lawn care needs.

What We Like
Effective weed control
Resistance management
Safe for bermudagrass greens
Easy mixing and application
Cost-effective low rates
#TOP 10

Southern Ag Atrazine St. Augustine Weed Killer

006130
Light Tan
Southern Ag Atrazine St. Augustine Weed Killer Cover
Southern Ag 006130 Atrazine St. Augustine Weed Killer 32oz Specialty Herbicide, Light Tan

The Southern Ag Atrazine St. Augustine Weed Killer is a highly effective specialty herbicide that controls weeds in St. Augustine and Centipede Grasses. With one quart treating 3,720 sq ft, it is perfect for large lawn areas. The lightweight package makes it easy to handle and store, with dimensions of 5.842 L x 19.177 H x 12.954 W (centimeters).

What We Like
Highly effective in controlling weeds in St. Augustine and Centipede Grasses
Covers a large area of 3,720 sq ft per quart
Lightweight and easy to handle and store
Buying Guide Image

Frequently Asked Questions (FAQs)

1. How do you kill weeds in Southern grass?

For killing weeds in Southern grass, Roundup For Lawns4 is a recommended option. It is a tough weed killer specifically designed for Southern grasses. This product effectively eliminates 93 types of weeds, including dollarweed, dandelion, clover, and yellow nutsedge, while preserving the health of the grass.

2. What weed killer kills everything but grass?

SedgeHammer® Herbicide is a suitable weed killer that targets nutsedge weeds without harming the grass. It comes in a Water Dispersible Granule (WDG) form and needs to be mixed with water for application. While it may take up to 21 days to show results, it is an effective option for controlling nutsedge without damaging the grass.

3. Is bleach or vinegar better for weeds?

Bleach is a potent weed killer that can effectively eliminate mature weeds and prevent new ones from growing. Unlike vinegar, bleach remains in the soil, providing longer-lasting weed control. However, it's important to note that bleach is a more noxious substance compared to vinegar.

4. Does vinegar kill weeds permanently?

Vinegar, being acidic, can kill most broadleaf weeds. However, it primarily affects the leaves and may not reach the root system, leading to potential regrowth. For more long-lasting results, a mixture of 1 cup of table salt with 1 gallon of vinegar can be used, as the salt helps dry out the weed's root system.

5. What kills weeds permanently but not grass?

To kill weeds permanently without harming grass, it is recommended to use a selective herbicide. Selective herbicides target specific weeds while leaving the grass unharmed. It is important to carefully read and follow product labels to ensure proper usage. Non-selective herbicides, on the other hand, can kill any plant they come in contact with, including grass.

6. How do I permanently get rid of weeds in my gravel driveway?

Rock salt can be an effective and natural weed killer for gravel driveways. Simply sprinkle rock salt on the areas with weeds, and over time, it will kill them. However, it's important to note that rock salt can also harm nearby plants, so it should be used with caution and only in areas where you want to eliminate vegetation.

Editor's Notes

During our southern weed killer research, we found 24 southern weed killer products and shortlisted 10 quality products. We collected and analyzed 9,326 customer reviews through our big data system to write the southern weed killers list. We found that most customers choose southern weed killers with an average price of $54.69.

The southern weed killers are available for purchase. We have researched hundreds of brands and picked the top brands of southern weed killers, including Southern Ag, Ortho, BioAdvanced, GORDON'S, PBI / Gordon. The seller of top 1 product has received honest feedback from 3,416 consumers with an average rating of 4.9.

Written by
Steven Taylor Avatar

Steven Taylor grew up in a small town called Beaufort in South Carolina and his passion for building and woodworking has led him to master the latest garden gadgets. He always holds every chance to patch up or sand down his beloved garden. There are various novel technologies in his articles.