Best Hypoallergenic Night Creams of 2025

Lisa Bechard Avatar
Lisa Bechard
Last Updated: Jan 6, 2025

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Hypoallergenic night creams are a great option for individuals with sensitive skin. These creams are formulated to be free of common allergens and irritants, making them suitable for those prone to redness, rashes, or other skin reactions. They typically contain gentle, nourishing ingredients that work to hydrate and repair the skin while you sleep, without causing any irritation. Whether you have dry, oily, or combination skin, hypoallergenic night creams can provide the moisture and nourishment your skin needs without the risk of allergic reactions.

At a Glance: Our Top Picks

Aveeno Positively Radiant Night Cream Cover #TOP 1
Aveeno Positively Radiant Night Cream
ftb score rating icon 9.9
Aveeno Ageless Restorative Night Cream Cover #TOP 2
Aveeno Ageless Restorative Night Cream
ftb score rating icon 9.8
Cetaphil Healthy Renew Night Cream Cover #TOP 3
Cetaphil Healthy Renew Night Cream
ftb score rating icon 9.6

Top 10 Hypoallergenic Night Creams

Aveeno Positively Radiant Night Cream

381371162499
Multi
Aveeno Positively Radiant Night Cream Cover
Aveeno Positively Radiant Intensive Moisturizing Night Cream with Total Soy Complex & Vitamin B3, Oil-Free, Non-Greasy, Hypoallergenic & Non-Comedogenic, 1.7 oz

The Aveeno Positively Radiant Night Cream is a facial moisturizer that brightens and evens skin tone while hydrating overnight. It contains soy and Vitamin B3 to leave skin feeling silky and looking more radiant while reducing the look of dark spots. This hypoallergenic cream is suitable for all skin types and is oil-free, paraben-free, phthalate-free, and dye-free. Clinically proven to improve skin tone and texture, 91% of users reported softer, smoother skin after just one week of use.

What We Like
Brightens and evens skin tone
Reduces the look of dark spots
Hydrates skin overnight

Aveeno Ageless Restorative Night Cream

AVO16377
Aveeno Ageless Restorative Night Cream Cover
Aveeno Absolutely Ageless Restorative Night Cream Face & Neck Moisturizer with Antioxidant-Rich Blackberry Complex, Vitamin C & E, Hypoallergenic, Non-Greasy & Non-Comedogenic, 1.7 fl. oz

Aveeno Ageless Restorative Night Cream is a dermatologist-recommended facial night cream that works overnight to moisturize and nourish skin. The formula features antioxidant-rich Blackberry Complex infused with Vitamins C and E, a proprietary blend of effective skincare ingredients. It is clinically proven to help improve the appearance of fine lines and wrinkles, and helps reduce the appearance of wrinkles to improve the look of collagen-depleted skin for improved elasticity and firmer-looking skin. It is non-greasy, hypoallergenic, and non-comedogenic, making it a great addition to a regular nighttime skincare routine.

What We Like
Clinically proven to help improve the appearance of fine lines and wrinkles
Contains antioxidant-rich Blackberry Complex infused with Vitamins C and E
Non-greasy, hypoallergenic, and non-comedogenic

Cetaphil Healthy Renew Night Cream

0299.026001
Cetaphil Healthy Renew Night Cream Cover
Cetaphil Healthy Renew Skin Tightening Night Cream 1.7 Oz, Wrinkle Repair Cream for Face with Peptides, Retinol Alternative Cream For Sensitive Skin, Fragrance Free

Cetaphil Renew Night Cream is a nourishing and gentle anti-aging cream designed specifically for sensitive skin. With its unique formula, it visibly reduces the appearance of fine lines and wrinkles in just two weeks. This night cream hydrates the skin for up to 48 hours, leaving it looking rested, glowing, and revitalized. Unlike traditional retinol creams, this cream uses purified peptides as a gentler alternative for sensitive skin, providing anti-aging benefits without increasing sensitivity to the sun. In addition, the cream respects the skin's natural moisture barrier with the help of vitamins B3 and B5, which hydrate, soothe, and restore the skin. Botanical extracts target visible dullness and uneven skin tone, resulting in a more radiant complexion. The hypoallergenic and fragrance-free formula has been tested by dermatologists, making it suitable for nightly use on sensitive skin. Protect your skin against dryness, irritation, roughness, tightness, and a weakened skin barrier with Cetaphil Renew Night Cream.

What We Like
Reduces fine lines and wrinkles
Nourishes and hydrates the skin
Gentle alternative to retinol

Cetaphil Rich Hydrating Night Cream

0299.388902
white
Cetaphil Rich Hydrating Night Cream Cover
CETAPHIL Rich Hydrating Night Cream For Face, With Hyaluronic Acid, 1.7 oz, Moisturizing Cream For Dry To Very Dry Skin, No Added Fragrance, (Packaging May Vary)

CETAPHIL Rich Hydrating Night Cream is an excellent choice for individuals with dry to very dry skin. With hyaluronic acid, this cream provides immediate and intense hydration for up to 24 hours. The lightweight, fast-absorbing, and non-greasy formula won't clog pores. CETAPHIL Rich Hydrating Night Cream also contains olive extract and pro-vitamin complex to help strengthen your skin's natural moisture barrier. This cream is hypoallergenic, fragrance-free, and gentle on sensitive skin.

What We Like
Moisturizing
Lightweight
No added fragrance
#TOP 5

Boots No7 Protect & Perfect Intense Almond Scented Night Cream

Boots
f-21
Ivory
Boots No7 Protect & Perfect Intense Almond Scented Night Cream Cover
Boots No7 Protect & Perfect Intense Almond Scented Night Cream - 1.69 Fl Oz - Gluten-Free, Hypoallergenic, Anti-Aging, SPF 15

Experience the power of Boots No7 Protect & Perfect Intense Almond Scented Night Cream. This hypoallergenic facial night cream is designed to visibly improve deep lines and wrinkles, giving you younger-looking skin. The cream also boosts radiance, leaving your skin with a healthy glow. With the added benefit of SPF 15, it provides protection against harmful UV rays. The almond scent adds a delightful touch to your nighttime skincare routine. Treat yourself to the convenience of a single product that addresses multiple concerns. Boots No7 Night Cream is the perfect addition to your anti-aging skincare regimen.

What We Like
Visibly improves deep lines & wrinkles
Boosts radiance for younger looking skin
With sunscreen
#TOP 6

Aveeno Absolutely Ageless Night Cream

Aveeno Absolutely Ageless Night Cream Cover
Aveeno Absolutely Ageless Restorative Night Cream Facial Moisturizer with Antioxidant-Rich Blackberry Complex, Vitamin C & E, Hypoallergenic, Non-Greasy & Non-Comedogenic, 1.7 fl. oz

The Aveeno Night Cream is designed to work overnight, providing deep hydration and nourishment to your skin. Its unique formula features an antioxidant-rich Blackberry Complex along with Vitamins C and E, which helps to combat signs of aging. You’ll notice a reduction in fine lines and wrinkles, leading to firmer and more elastic skin. Additionally, this cream strengthens your skin’s moisture barrier, promoting a healthier and more youthful appearance over time. Enjoy waking up to revitalized skin with this dermatologist-recommended moisturizer that is non-greasy and won't clog your pores.

What We Like
Reduces fine lines
Enhances skin elasticity
Deep hydration
Non-greasy formula
#TOP 7

MAKEPREM Safe Me. Relief Moisture Moisturizer Cream

MKPR1
2 Piece Set
MAKEPREM Safe Me. Relief Moisture Moisturizer Cream Cover
MAKEPREM Safe Me. Relief Moisture Moisturizer Cream for Dry Sensitive Skin 2 Pack - Night Cream Hydrating Nourishing - Reduce Redness Acne s - Hypoallergenic Natural VEGAN - EWG Verified

MAKEPREM Safe Me. Relief Moisture Moisturizer Cream is a hypoallergenic moisturizer that is ideal for sensitive and dry skin types. Its 12 ingredients are rated 0-2 (Green) from EWG and are clinically tested to be hypoallergenic and not skin irritating. The moisturizing effect lasts upto 48 hours by preventing moisture loss. It improves the overall skin conditions significantly (-24.24% in moisture loss, +9.66% improvement in skin redness, and +87.99% in moisturizing effect after 48 hours). It is also safe for infants, babies, children, and pregnant women.

What We Like
Hypoallergenic and non-irritating
Contains only 12 natural ingredients
Moisturizing effect lasts up to 48 hours

MAKEP:REM Safe Me. Relief Moisture Cream

SB0200029
with minis
MAKEP:REM Safe Me. Relief Moisture Cream Cover
MAKEP:REM Safe Me. Relief Moisture Cream for Dry Sensitive Skin - Moisturizer Night Cream - Hydrating & Nourishing, Reduce Redness, Acne & Wrinkles with Hypoallergenic, Natural - VEGAN, EWG Verified

MAKEP:REM Relief Moisture Cream is a hypoallergenic night cream that effectively moisturizes and soothes all skin types. With 93% natural ingredients, it is ideal for sensitive and dry skin. Its clinically tested formula prevents moisture loss for up to 48 hours, improving skin conditions by reducing redness and increasing moisturizing effects. The cosmetic spatula makes application easy, and its skin-friendly, non-irritating nature allows safe use for all, including infants and pregnant women. The Korean Date Notation may differ, so be mindful of expiry dates. Contact the seller for any product usage issues.

What We Like
Hypoallergenic
Clinically tested
Long-lasting moisture
#TOP 9

EASYDEW DW-EGF Peptide Retinol Cream

EASYDEW DW-EGF Peptide Retinol Cream Cover
EASYDEW DW-EGF Peptide Retinol 0.03% Cream – Beginner Retinol Night Cream for Hypoallergenic Skin Care - Firm Skin, Wrinkle Improvement - Korean Daily Anti Aging Face & Neck Treatment, 1ml

EASYDEW Retinol Night Cream is designed for nightly use, making it a great choice for those just starting with retinol. It helps improve skin density, tighten pores, and reduce the appearance of wrinkles, all while being gentle on your skin. The cream features DW-EGF Peptide, which boosts collagen production and works with retinol to enhance skin elasticity. Additionally, the formula combines retinol with seven peptides, hyaluronic acid, and collagen for deep absorption and effective results, ensuring your skin gets the nourishment it needs for a youthful glow.

What We Like
Hypoallergenic formulation
Boosts collagen production
Reduces wrinkles
Deep absorption
#TOP 10

EASYDEW DW-EGF Retinol Cream

EASYDEW DW-EGF Retinol Cream Cover
EASYDEW DW-EGF Peptide Retinol 0.03% Cream – Beginner Retinol Night Cream for Hypoallergenic Skin Care - Firm Skin, Wrinkle Improvement - Korean Daily Anti Aging Face & Neck Treatment, 1.01fl. oz.

The EASYDEW Retinol Cream is designed for nightly use, making it perfect for those new to retinol. This hypoallergenic formula helps improve skin density, tighten pores, and reduce the appearance of wrinkles. With its DW-EGF anti-aging technology, it significantly boosts collagen production, enhancing your skin's elasticity. The powerful combination of retinol, EGF, and additional peptides ensures that the cream penetrates deeply for effective results. By following the recommended usage, you can gradually increase application to enjoy the full benefits without irritation.

What We Like
Effective for beginners
Boosts collagen production
Reduces wrinkles
Hypoallergenic formula
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Why does my night cream burn my face?

According to Dr Alexis Stephens, the consulting dermatologist for Urban Skin Rx, a stinging sensation is most likely the result of a compromised skin barrier. Your face might have become sensitised, which is often the result of overusing harsh products (like chemical peels and acids or retinoids).

Editor's Notes

During our hypoallergenic night cream research, we found 48 hypoallergenic night cream products and shortlisted 10 quality products. We collected and analyzed 84,876 customer reviews through our big data system to write the hypoallergenic night creams list. We found that most customers choose hypoallergenic night creams with an average price of $17.02.

The hypoallergenic night creams are available for purchase. We have researched hundreds of brands and picked the top brands of hypoallergenic night creams, including TENA, Cetaphil, Boots, MAKEP:REM, EASYDEW. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Lisa Bechard Avatar

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.