Best Glycolic Acid Night Creams of 2025

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Glycolic Acid Night Creams are a popular skincare product that helps to exfoliate and renew the skin while you sleep. These creams are formulated with glycolic acid, a powerful alpha hydroxy acid that works to remove dead skin cells and improve the skin's texture and tone. They are often used to address concerns such as fine lines, wrinkles, and uneven skin tone, and can leave the skin looking smoother and more radiant with regular use. Many users report waking up with softer, more youthful-looking skin after incorporating a glycolic acid night cream into their nightly skincare routine.
At a Glance: Our Top Picks
Top 10 Glycolic Acid Night Creams
GUNILLA Glycolic Acid Night Cream
GUNILLA Glycolic Acid Night Cream is a botanically-based anti-aging formula that gently exfoliates dead skin cells, reduces fine lines and wrinkles, and increases collagen production. It is suitable for all skin types and contains 10% Glycolic Acid and 70% antioxidant-rich botanicals. The cream is cruelty-free, Leaping Bunny Certified, and free from harmful chemicals. A 90-day money-back guarantee is offered by the Certified Women-Owned Business.
Glytone Night Renewal Cream
Glytone Night Renewal Cream is a fragrance-free facial night cream that contains 5.5 Free Acid Value Glycolic Acid and Retinaldehyde. It exfoliates dead skin cells, reduces the appearance of sun spots and wrinkles, and leaves skin brighter and smoother with more even tone. To use, apply a small amount to your face and neck nightly and use daily sunscreen while using this product.
MAELOVE Night Renewer Glycolic Acid Cream
MAELOVE Night Renewer is designed to enhance your skin's texture while being gentle enough for sensitive skin. With 10% glycolic acid, it helps reduce dark spots and the visibility of lines and wrinkles, giving you a smoother appearance. The unique blend of soothing ingredients like Vitamin E and Aloe keeps your skin hydrated, making it an excellent choice for nighttime use. You might feel a slight tingling sensation as your skin adjusts, which indicates that the powerful ingredients are working effectively. This cream is a favorite among dermatologists for its effectiveness without harsh side effects.
OLOS Glycolic Acid Night Cream
The OLOS Night Cream is designed to rejuvenate your skin while you sleep. This glycolic acid cream gently exfoliates, helping to renew and smooth your skin, giving you a fresh, radiant appearance by morning. With the added benefit of Helichrysum, it enhances skin density, providing a youthful look. The formula also features Shea butter, which deeply hydrates, ensuring your skin remains soft and supple. Ideal for all skin types, this cream works effectively to remove blackheads and revitalize even sensitive skin, making it a perfect addition to your nighttime skincare routine.
Cosmedica Skincare Hydrating Night Cream
The Cosmedica Skincare Multi-Active Hydrating Night Cream is a non-greasy, lightweight, fast-absorbing, and residue-free formula suitable for all skin types. It helps even skin tone and texture, reduce dark spots, acne scars, hyperpigmentation, and redness. The cream provides deep hydration and moisture, targeting fine lines and wrinkles to reveal ageless beauty and flawless skin. The naturally derived formulation uses premium moisturizing ingredients like vitamin C, Lactic Acid, Castor Oil, Aloe Vera, Jojoba Oil, Coconut Oil, Hyaluronic Acid, Squalene, Rosehip Seed Oil, and Vitamin B5. For best results, pair it with Hyaluronic Acid Serum or Vitamin C Serum to provide moisture for dry skin and the best anti-aging night cream.
NUVADERMIS Collagen & Retinol Cream with Glycolic Acid Pads
The NUVADERMIS Anti-Aging Cream offers a powerful blend of collagen and retinol to help you achieve youthful, radiant skin. This moisturizer is designed to minimize the appearance of fine lines, wrinkles, and dark circles, making your skin look firmer and smoother. The inclusion of hyaluronic acid ensures deep hydration, leaving your skin feeling refreshed. Additionally, the 35% glycolic acid pads provide a convenient way to exfoliate, unclog pores, and enhance your skin’s overall texture. With green tea and vitamins C and E, these pads nourish and soothe your skin, helping you achieve that desired glow.
Deluvia Turbo Cream
Deluvia Night Moisturizer is a premium quality cream made with organic aloe vera, hyaluronic acid, and botanical oils. It moisturizes your skin while targeting wrinkles, dark spots, and signs of aging. The unique combination of organic aloe vera, rosehip oil, and botanicals helps maintain skin moisture and reduce the appearance of fine lines and wrinkles. It is suitable for all skin types and can be used day and night. Plus, it comes with a 100% satisfaction guarantee, offering a risk-free purchase.
Caudalie Vinoperfect Glycolic Night Cream
The Caudalie Vinoperfect Dark Spot Glycolic Night Cream is a rich and effective formula that acts as a gentle overnight peel to reveal fresh and luminous skin. It reduces dark spots, smooths the surface, evens skin tone, and provides continuous brightness and deep moisturization. After removing makeup, cleansing, and toning, applying a thin layer to your face, neck, and chest is an essential step in your nightly routine. The products are made from natural resources, particularly vine and grape extracts, and are never tested on animals or created from animal-derived raw materials.
Pure Zivaª Glycolic Acid & Green Tea Night Cream
Pure Zivaª Night Recharge Skin Facial Cream contains glycolic acid and botanical extracts that help to reduce the appearance of fine lines and wrinkles, even out skin tone and texture, and stimulate cell turnover. It's an oil-free cream that doesn't cause visible peeling. The product is gluten, paraben and sulfate free, and cruelty-free. Users can receive 10% off 2 items and 15% off 3 or more items in their catalog by using the claim code PUREZIVA at checkout. Made in the USA.
Shira Nutriburst Night Cream
Shira Nutriburst Cream is designed to rejuvenate your skin while you sleep. It features Hyaluronic Acid and Collagen, which work together to enhance your skin's radiance and smoothness. Glycolic Acid helps repair sun-damaged skin, promoting deeper regeneration for a healthier complexion. Additionally, lipid-encapsulated peptides provide intense hydration, ensuring your skin feels nourished and plump. This powerful combination not only fights signs of aging but also strengthens your skin's barrier, making it more resilient against environmental stressors.
During our glycolic acid night cream research, we found 48 glycolic acid night cream products and shortlisted 10 quality products. We collected and analyzed 6,057 customer reviews through our big data system to write the glycolic acid night creams list. We found that most customers choose glycolic acid night creams with an average price of $24.54.
The glycolic acid night creams are available for purchase. We have researched hundreds of brands and picked the top brands of glycolic acid night creams, including Gunilla Of Sweden, GLYTONE, MAELOVE, OLOS, Cosmedica Skincare. The seller of top 1 product has received honest feedback from 70 consumers with an average rating of 4.7.

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.