Best Naproxen Sodium of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 18, 2026

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Naproxen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation caused by conditions such as arthritis, menstrual cramps, and sprains. It works by reducing the production of prostaglandins, which are responsible for causing pain and inflammation in the body. Naproxen Sodium is available over-the-counter in the form of tablets, capsules, and liquid gels. It is important to follow the recommended dosage and not to exceed the maximum daily dose, as overuse can lead to serious side effects such as stomach ulcers and kidney problems.

At a Glance: Our Top Picks

Amazon Basic Care Naproxen Sodium Tablets Cover #TOP 1
Amazon Basic Care Naproxen Sodium Tablets
ftb score rating icon 9.8
Amazon Basic Care Naproxen Sodium Tablets Cover #TOP 2
Amazon Basic Care Naproxen Sodium Tablets
ftb score rating icon 9.7
Aleve Naproxen Sodium Arthritis Gelcaps 160 Count Cover #TOP 3
Aleve Naproxen Sodium Arthritis Gelcaps 160 Count
ftb score rating icon 9.5

Top 10 Naproxen Sodium

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Amazon Basic Care Naproxen Sodium Tablets

Amazon Basic Care
Tablets
200 Count
Amazon Basic Care Naproxen Sodium Tablets Cover
Amazon Basic Care Naproxen Sodium Tablets, 200 Count (Pack of 1) (Packaging may vary)

Amazon Basic Care Naproxen Sodium Tablets, also known as Amazon Naproxen Sodium Tablets, is a pain reliever and fever reducer that contains naproxen sodium 220 mg. This nonsteroidal anti-inflammatory drug (NSAID) provides up to 12 hours of relief from aches and pains, allowing you to get through your day. It temporarily relieves minor aches and pains caused by arthritis, muscular aches, backache, menstrual cramps, headache, toothache, and the common cold. Additionally, it can temporarily reduce fever. These capsule-shaped tablets are gluten-free and suitable for adults and children aged 12 years and over. With Amazon Naproxen Sodium Tablets, you can experience all-day relief and get back to doing what you love.

What We Like
Fast acting relief
Affordable price
Small, easy to swallow
Generic alternative to top brands
Effective for headaches and muscle pain
What We Don't Like
Possible risk with long-term use
May affect kidney health
#TOP 2

Amazon Basic Care Naproxen Sodium Tablets

Amazon Basic Care
Tablets
300 Count
Amazon Basic Care Naproxen Sodium Tablets Cover
Amazon Basic Care Naproxen Sodium Tablets 220 mg, Pain Reliever/Fever Reducer (NSAID), Muscular Aches, Backache, Headache, Toothache, Minor Arthritis Pain Relief & More, 300 Count (Packaging may vary)

Amazon Basic Care Naproxen Sodium Tablets contain 220mg of naproxen sodium, a nonsteroidal anti-inflammatory drug (NSAID), which provides temporary relief from minor aches and pains due to various causes such as arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold. These capsule-shaped tablets are gluten-free and can provide up to 12 hours of pain relief and fever reduction for adults and children age 12 years and over.

What We Like
Effective pain relief
Affordable price
Works as well as name brands
Small, easy-to-swallow tablets
Fast-acting, long-lasting
What We Don't Like
Possible kidney concerns with long-term use
#TOP 3

Aleve Naproxen Sodium Arthritis Gelcaps 160 Count

Yellow
Aleve Naproxen Sodium Arthritis Gelcaps 160 Count Cover
Aleve Gelcaps with Easy Open Arthritis Cap, Naproxen Sodium, Medication for Arthritis Pain, 160 Count

Aleve Arthritis Pain Relief offers up to 12 hours of continuous pain relief, helping you manage arthritis discomfort as well as muscle aches, back pain, menstrual cramps, headaches, toothaches, and cold symptoms. The bottle is designed with an easy-to-open, cushioned cap and a contoured shape, making it simpler to handle if you have arthritis or limited hand strength. In addition to pain relief, this product also helps reduce fever for adults and children over 12. With naproxen sodium as the active ingredient, it targets minor arthritis pain effectively, giving you longer-lasting comfort throughout your day.

What We Like
Long-lasting pain relief
Easy-open arthritis cap
Fever reduction
Targets arthritis pain
What We Don't Like
Poor delivery experience
#TOP 4

Aleve Back & Muscle Pain Relief Tablets - 250 Count

025866592285
White
Aleve Back & Muscle Pain Relief Tablets - 250 Count Cover
Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets, Pain Reliever & Fever Reducer, Medicine for Body , 250 Count

Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets provide targeted pain relief for minor back and muscle aches and pains. The tablets are easy to swallow and offer long-lasting pain relief, lasting up to 12 hours. The child-resistant packaging ensures safety, and the fast-acting formula provides effective relief.

What We Like
Fast-acting formula
Long-lasting pain relief
Easy to swallow
Child-resistant packaging
#TOP 5

Aleve Liquid Capsules, Pain Reliever/Fever Reducer, 120 Count

BY-278
No Artificial Color
Aleve Liquid Capsules, Pain Reliever/Fever Reducer, 120 Count Cover
Aleve Liquid Capsules, Naproxen Sodium Capsules 220 mg (NSAID), Pain Reliever/Fever Reducer, Fast Pain Relief, 120 Count

Aleve Liquid Capsules is an over-the-counter (OTC) pain reliever and fever reducer in liquid capsules form that provides fast and continuous pain relief for up to 12 hours. It is designed to be stronger and longer-lasting on pain than Tylenol, with just two pills needed for all-day relief.

What We Like
Fast pain relief
Effective for back pain
Reliable for flu symptoms
Easy online availability
Better than Tylenol
What We Don't Like
Occasionally hard to find in stores
#TOP 6

Aleve Naproxen Sodium Caplets 50 Count

1029464
Aleve Naproxen Sodium Caplets 50 Count Cover
Aleve Pain Relief Naproxen Sodium Caplets ‐ 50 Count

The Aleve Pain Relief Caplets are designed to provide you with up to 12 hours of continuous relief from common aches such as arthritis, headaches, and back pain. If you’re dealing with a fever, these caplets can help reduce it temporarily, suitable for adults and kids 12 and older. Each tablet contains 220 mg of naproxen sodium, a powerful ingredient that targets muscle and back pain effectively. Research shows that these caplets work longer and just as well as some prescription painkillers, making them a convenient option for managing your pain throughout the day. Always check with your doctor to see if Aleve is right for you.

What We Like
Effective pain relief
Long-lasting effect
Works for multiple pain types
Better than acetaminophen or ibuprofen
Good value for money
What We Don't Like
Possible kidney concerns with daily use
#TOP 7

Aleve PM Sleep Aid Plus Pain Reliever 120 Count

025866592582
Blue
Aleve PM Sleep Aid Plus Pain Reliever 120 Count Cover
Aleve PM Sleep Aid Plus Pain Reliever Caplets, Naproxen Sodium & Diphenhydramine HCl, Nighttime, 120 Count

Aleve PM Sleep Aid is designed to help you enjoy a restful night's sleep while easing minor aches and pains. If you struggle with occasional sleeplessness caused by discomfort, this product can support you in falling asleep more easily and staying asleep throughout the night. It combines a sleep aid with Aleve's powerful 12-hour pain relief, giving you the convenience of addressing both sleep and pain in one. With ingredients that work to calm your body and reduce pain, Aleve PM Sleep Aid helps you wake up feeling refreshed and ready for the day.

What We Like
Dual sleep and pain relief
12-hour pain relief strength
Helps fall and stay asleep
Relieves minor aches and pains
What We Don't Like
Unusual dreams
#TOP 8

Aleve Pain Relief Naproxen Sodium Tablets

025866593442
Blue
Aleve Pain Relief Naproxen Sodium Tablets Cover
Aleve Pain Reliever & Fever Reducer Tablets, Naproxen Sodium, Headache, Back and Body Pain Relief Medicine, 270 Count

Aleve Pain Relief Naproxen Sodium Tablets provide up to 12-hour pain relief, reduce fever and effectively relieve minor pain caused by arthritis, menstrual cramps, muscular aches, backache, toothache, headache and the common cold. It comes in a child-resistant bottle and is recommended by orthopedic surgeons for minor arthritic pain.

What We Like
Effective pain relief
Long-lasting results
Better than ibuprofen
Value for money
Long shelf life
What We Don't Like
Country of origin concerns
Higher price than generics
#TOP 9

Aleve Naproxen Sodium Pain Reliever 60 Pouches

025866593763
Blue
Aleve Naproxen Sodium Pain Reliever 60 Pouches Cover
Aleve Pain Reliever & Fever Reducer Naproxen Sodium Caplets, Body and Arthritis Pain Reliever, Medicine for Adults and Children Ages 12 and Up, 60 Individual Pouches

The Aleve Pain Reliever Gelcaps are designed to provide you with reliable pain relief wherever you go. These portable gelcaps make it easy to manage pain on the move, so you don’t have to be held back by discomfort. They offer up to 12 hours of continuous relief, helping you handle muscle aches, arthritis, back pain, headaches, and cramps without frequent dosing. If you have a fever, these gelcaps can temporarily reduce it, making them useful for both adults and children over 12. Additionally, they target minor pains from various sources like colds and joint pain, giving you versatile and effective relief when you need it most.

What We Like
Portable individual packets
Convenient for travel and bags
Easy to share hygienically
Suitable for first aid kits
Effective pain relief
What We Don't Like
Slightly higher price
Extra packaging waste
#TOP 10

GoodSense Naproxen Sodium Tablets 220 mg, 400 Count

S001392
GoodSense Naproxen Sodium Tablets 220 mg, 400 Count Cover
GoodSense Naproxen Sodium Tablets, 220 mg, 400 Count

GoodSense Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer that contains naproxen sodium 220 mg, providing up to 12 hours of relief. It temporarily relieves minor aches and pains due to arthritis, muscular aches, backache, menstrual cramps, headache, toothache, and the common cold; also temporarily reduces fever. The capsule-shaped tablets are gluten-free and suitable for adults and children age 12 years and over.

What We Like
Effective pain relief
Affordable price
Good for joint pain
Comparable to brand name
Anti-inflammatory benefits
What We Don't Like
Requires careful dosage management
Potential for internal bleeding
Buying Guide Image

Get the Best Naproxen Sodium

Understanding Naproxen Sodium

Naproxen sodium is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain and inflammation. It is available over-the-counter and in prescription form, and is sold under a variety of brand names including Aleve, Anaprox, and Naprosyn.

Indications for Use

Naproxen sodium is most commonly used to treat conditions that cause pain and inflammation, such as headaches, muscle aches, arthritis, and menstrual cramps. It can also be used to reduce fever and to relieve the pain and swelling associated with acute injuries, such as sprains and strains.

Potential Side Effects

Like all medications, naproxen sodium can cause side effects. The most common side effects include stomach upset, heartburn, nausea, and dizziness. More serious side effects may include stomach ulcers, bleeding, and kidney problems. If you experience any of these side effects, it is important to contact your doctor right away.

Precautions and Contraindications

Before taking naproxen sodium, it is important to talk to your doctor if you have any underlying medical conditions, such as heart disease, liver disease, or kidney disease. Naproxen sodium may not be suitable for people who are taking certain medications, such as blood thinners or steroids. It is also important to avoid alcohol while taking naproxen sodium, as it can increase the risk of stomach ulcers and bleeding.

Choosing the Right Dosage

The appropriate dosage of naproxen sodium will vary depending on the severity of your symptoms and your individual medical history. It is important to follow your doctor's instructions and to take the medication exactly as prescribed. Overdose can be dangerous and can cause serious side effects, so it is important to never take more than the recommended dosage.

Conclusion

Naproxen sodium can be an effective medication for relieving pain and inflammation, but it is important to choose the right dosage and to use it safely. If you have any concerns about taking naproxen sodium, talk to your doctor before starting the medication.

Frequently Asked Questions (FAQs)

1. What is naproxen sodium used for?

Naproxen sodium is used to reduce fever and relieve mild pain from various sources, including headaches, muscle aches, arthritis, menstrual periods, the common cold, toothaches, and backaches. It belongs to a class of medications called NSAIDs (nonsteroidal anti-inflammatory drugs).

2. Is naproxen stronger than ibuprofen?

Naproxen (Aleve) and ibuprofen (Advil or Motrin) are both effective NSAIDs for pain relief. While ibuprofen often provides faster pain relief, naproxen is longer-lasting. Both medications have their benefits and can be used depending on the individual's needs and the type of pain they are experiencing.

3. Is naproxen sodium a strong painkiller?

Naproxen sodium is a powerful anti-inflammatory painkiller that is commonly used to relieve pain and inflammation associated with various health conditions such as arthritis, gout, or menstrual pain. It is effective in providing pain relief and reducing inflammation.

4. What should I avoid when taking naproxen?

When taking naproxen, it is advisable to avoid other anti-inflammatory medicines like aspirin or ibuprofen. Additionally, medications that help prevent blood clots (such as warfarin or rivaroxaban), steroids (such as prednisolone), and diuretics that increase urination (such as furosemide) should be avoided.

5. Is naproxen 500 mg a narcotic?

No, naproxen is not a narcotic pain medication. However, it is commonly used for relieving minor pains, body aches, and headaches. Many people find naproxen to be an effective over-the-counter medication for mild to moderate aches and pains.

6. What's stronger ibuprofen 800 or naproxen 500?

Both naproxen 500 mg and ibuprofen 800 mg are generally equally effective in relieving pain since they work in the same way. However, the duration of pain relief may differ. Naproxen (Aleve) typically lasts 8-12 hours, while ibuprofen (Advil) lasts 4-6 hours. The choice between the two may depend on the type of pain and individual preferences.

7. Which is better for inflammation, Tylenol or naproxen?

NSAIDs like aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve, Anaprox) may be more effective than acetaminophen (Tylenol) for certain conditions because they not only relieve pain but also reduce inflammation. If you are specifically looking for relief from inflammation, naproxen may be a better choice.

Editor's Notes

During our naproxen sodium research, we found 26 naproxen sodium products and shortlisted 10 quality products. We collected and analyzed 464,767 customer reviews through our big data system to write the naproxen sodium list. We found that most customers choose naproxen sodium with an average price of $17.79.

The naproxen sodium are available for purchase. We have researched hundreds of brands and picked the top brands of naproxen sodium, including Aleve, GoodSense. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.

Naproxen Sodium Comparison Table

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Brand Amazon Basic Care Amazon Basic Care Aleve Aleve Aleve Aleve Aleve Aleve Aleve GoodSense
Item dimensions L x W x H 2 x 4.25 x 2.03 inches 2.2 x 2.2 x 4.5 inches 3.07 x 3.07 x 5.75 inches 3 x 2.63 x 4.88 inches 2.63 x 2.63 x 4.88 inches 2.5 x 2.06 x 3.97 inches 2.5 x 2.06 x 4.38 inches 3 x 2.63 x 4.88 inches 5.13 x 3.31 x 5.88 inches -
Product Benefits Muscle Therapy Fever Control Fever Control, Headaches, Muscle Therapy, Pain Relief Back Pain Relief Arthritis Control Body Pain Relief Pain Relief Pain Relief Pain Relief -
Specific Uses For Product Fever Arthritis arthritis, backache, headache, muscular aches, menstrual cramps, toothaches Arthritis, Backache, Fever, Headache, Muscle Pain Pain Relief Arthritis, Backache, Headache Pain Relief Temporarily relieves minor aches and pains due to: minor pain of arthritis, backache, headache, muscular aches, menstrual cramps, toothaches Temporarily relieves minor aches and pains due to: minor pain of arthritis, backache, headache, muscular aches, menstrual cramps & toothaches -
Item Weight 0.2 Pounds 0.24 Pounds - 4.51 ounces 0.5 Pounds 1.4 Ounces - 0.29 Pounds - -
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.4
ftb score rating icon 9.3
ftb score rating icon 9.2
ftb score rating icon 9.1
ftb score rating icon 9.0
ftb score rating icon 9.0
ftb score rating icon 8.9
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